Search
Results: 78915
Research on the Influential Factors of Bilingual Teaching Based on Colin Baker Model Case Study of Macroeconomics
Bilingual teaching is the manifestation of the internationalization of high education and the key index of undergraduate teaching evaluation. Based on the modified Colin Baker model and the questionnaire of two universities in...
Published by: IGI Global Scientific Publishing
The Grizzly, September 26, 1995
Marc Ellman, Mark Leiser, Melissa Forbes, Janine Soper, Erin Callahan, Denelle Godek, Vidya Setty, Tarik Qasim, Brandy McLachlan, Christy Kenny, Todd Brenneman, Geoffrey Mills, Colin Tucker, Amy K. Davenport, Kim Ryan, Jeff Lehrman, Christina Dappollone, Joel Schofer, Charlie Weingroff
Jan 01, 0001
Ursinus Improves in National Rankings Racism in Everywhere The Dawn of a New S.T.A.R. Royersford Teachers Strike Restaurant Night is Back! Stories from Abroad Help, I'm an E-mail Addict! Political Parties, Presidents, and...
Ursinus College Collegeville Pennsylvania newspaper Volleyball Football Soccer field hockey cross country energy conservation campus security student government Diversity Hillel Wismer dining hall Steve Tobin Lisa Manderach homophobia study abroad Charles Blockson college rankings cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Facilitating Programme-Level Assessment Working Teams to Develop Shared Rubrics Across a UG and PG Programme Portfolio in Business Education
This chapter is a reflective study reporting on a College-wide common rubrics initiative in a Technological University (TU) in Ireland. Assessment and feedback are enduring issues for the higher education sector both in Ireland...
classroom management Education Learning Assessment and Measurement Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
A Software Design Model for Integrating LMS and MOOCs
Instructors often experience difficulties in selecting and sequencing relevant content for deployment into learning management systems. Human error and subjectivity is apparent. This study focuses on integrating learning...
Published by: IGI Global Scientific Publishing
Ultrahigh-Throughput Directed Evolution of a Metal-Free α/β-Hydrolase with a Cys-His-Asp Triad into an Efficient Phosphotriesterase.
J David Schnettler, Oskar James Klein, Tomasz S Kaminski, Pierre-Yves Colin, Florian Hollfelder
Jan 19, 2023
Finding new mechanistic solutions for biocatalytic challenges is key in the evolutionary adaptation of enzymes, as well as in devising new catalysts. The recent release of man-made substances into the environment provides a...
A scoping review of the potential for chart stimulated recall as a clinical research method.
BACKGROUND: Chart-stimulated recall (CSR) is a case-based interviewing technique, which is used in the assessment of clinical decision-making in medical education and professional certification. Increasingly, clinical...
Chart stimulated recall Decision Making General Practice qualitative research SCOPING REVIEW Clinical Competence Clinical Decision-Making Female Guideline Adherence Humans Interviews as Topic Male Medical Records Mental Recall Primary Health Care qualitative research Reproducibility of Results Research Design
A scoping review of the potential for chart stimulated recall as a clinical research method.
Humans Medical Records Reproducibility of Results Mental Recall qualitative research Research Design Clinical Competence Primary Health Care Guideline Adherence Female Male Interviews as Topic Clinical Decision-Making
Published by: BMC health services research
One in a million
Anastasia Zinchenko, Sean RA Devenish, Balint Kintses, Pierre-Yves Colin, Martin Fischlechner, Florian Hollfelder
Jan 22, 2021
Directed evolution relies on iterative cycles of randomization and selection. The outcome of an artificial evolution experiment is crucially dependent on (i) the numbers of variants that can be screened and (ii) the quality of...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Bioinspired genotype-phenotype linkages
The idea of compartmentalization of genotype and phenotype in cells is key for enabling Darwinian evolution. This contribution describes bioinspired systems that use in vitro compartments-water-in-oil droplets and gel-shell...
Identification and Characterisation of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2 : C48R
N Ramanathan, M Ahmed, E Raffan, CL Stewart, S O'Rahilly, RK Semple, H Raef, JJ Rochford
Feb 05, 2020
Loss-of-function mutations in AGPAT2, encoding 1-acylglycerol-3-phosphate-O-acyltransferase 2 (AGPAT2), produce congenital generalised lipodystrophy (CGL). We screened the AGPAT2 gene in two siblings who presented with...
Cardiac Energetics Before, During, and After Anthracycline-Based Chemotherapy in Breast Cancer Patients Using 31P Magnetic Resonance Spectroscopy
Human pluripotent stem cell-based models suggest preadipocyte senescence as a possible cause of metabolic complications of Werner and Bloom Syndromes.
Werner Syndrome (WS) and Bloom Syndrome (BS) are disorders of DNA damage repair caused by biallelic disruption of the WRN or BLM DNA helicases respectively. Both are commonly associated with insulin resistant diabetes, usually...
Factors to Consider When Designing Multimedia CBL Tools in Health Professional Programs
Multimedia case studies are effective constructivist instructional tools that can help to design contextually authentic scenarios while also scaffolding instruction to help students move beyond their current skill and knowledge...
Published by: IGI Global Scientific Publishing
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Winthrop Staff and Student Take Leadership Role in SCIRSA
Winthrop University
Jan 01, 0001
Quick Facts
Cameron Edwards will serve as the S.C. representative for a two-year term on the National Intramural-Recreational Sports Association (the NIRSA) Region II Leadership Team. One of his duties involves working with the...
Published by: Winthrop University
Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy.
Gemma V Brierley, Hannah Webber, Eerika Rasijeff, Sarah Grocott, Kenneth Siddle, Robert K Semple
Sep 04, 2020
Loss-of-function mutations in both alleles of the human insulin receptor gene (INSR) cause extreme insulin resistance (IR) and usually death in childhood, with few effective therapeutic options. Bivalent antireceptor antibodies...
Evidence of a Causal Association Between Insulinemia and Endometrial Cancer
Kevin T Nead, Stephen J Sharp, Deborah J Thompson, Jodie N Painter, David B Savage, Robert K Semple, Adam Barker, Australian National Endometrial Cancer Study Group (ANECS), John RB Perry, John Attia, Alison M Dunning, Douglas F Easton, Elizabeth Holliday, Luca A Lotta, Tracy O'Mara, Mark McEvoy, Paul DP Pharoah, Rodney J Scott, Amanda B Spurdle, Claudia Langenberg, Nicholas J Wareham, Robert A Scott
Jun 19, 2015
Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models.
AIMS/HYPOTHESIS: Bi-allelic loss-of-function mutations in the INSR gene (encoding the insulin receptor [INSR]) commonly cause extreme insulin resistance and early mortality. Therapeutic options are limited, but anti-INSR...
Diabetes Donohue Syndrome Insulin receptor Insulin Resistance Insulin signalling Monoclonal antibodies Rabson–Mendenhall syndrome 3T3-L1 Cells Adipocytes Animals Antibodies Antigens CD CHO Cells Cricetulus Glucose Humans Hypoglycemic Agents Insulin Insulin Resistance Mice Mutation Phosphorylation Receptor Insulin Signal Transduction
Clinical experience with the AKT1 inhibitor miransertib in two children with PIK3CA-related overgrowth syndrome.
Karina Forde, Nicoletta Resta, Carlotta Ranieri, David Rea, Olga Kubassova, Mark Hinton, Katrina A Andrews, Robert Semple, Alan D Irvine, Veronika Dvorakova
Feb 27, 2021
BACKGROUND: PIK3CA-related overgrowth spectrum (PROS) refers to a group of rare disorders, caused by somatic activating mutations in PIK3CA, resulting in abnormal PI3K-AKT-mTOR pathway signalling. Significant associated...
Nephroblastomatosis or Wilms tumor in a fourth patient with a somatic PIK3CA mutation.
Karen W Gripp, Laura Baker, Vinay Kandula, Katrina Conard, Mena Scavina, Joseph A Napoli, Gregory C Griffin, Mihir Thacker, Rachel G Knox, Graeme R Clark, Victoria ER Parker, Robert Semple, Ghayda Mirzaa, Kim M Keppler-Noreuil
Jun 07, 2016
CLOVES PIK3CA-related overgrowth Wilms tumor hemihyperplasia hemihypertrophy lipoma nephroblastomatosis Somatic mutation Alleles Amino Acid Substitution Child Child Preschool Class I Phosphatidylinositol 3-Kinases Female Genetic Association Studies Genetic Testing Heterozygote Humans Infant Magnetic Resonance Imaging Male Mutation Phenotype Tomography X-Ray Computed Ultrasonography Wilms Tumor
|
|< |
< |
1 |