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The Amyloid-β Pathway in Alzheimer's Disease.
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular mechanisms of the pathway and the spatial-temporal dynamics...
Purification and Characterization of OTF-l, A Transcription Factor Regulating Cell Cycle Expression of a Human Histone H2b Gene: Demonstration of its Functional Identity with NF-III, a Factor Required for Efficient Initiation of Adenovirus DNA Replication
Colin F Fletcher
Jan 01, 0001
An octamer-binding transcription factor, OTF-l, which stimulates transcription of a human histone H2b gene, has been purified from HeLa nuclear extracts. This purification was achieved through the use of DNA affinity...
Published by: Rockefeller University
The amyloid-β pathway in Alzheimer's disease
WHAT IS THIS SUMMARY ABOUT?: This plain language summary of an article published in Molecular Psychiatry, reviews the evidence supporting the role of the amyloid-β (Aβ) pathway and its dysregulation in Alzheimer's disease (AD)...
Research on the Influential Factors of Bilingual Teaching Based on Colin Baker Model Case Study of Macroeconomics
Wen-Jing Fan, Pan Xian
Dec 23, 2022
Bilingual teaching is the manifestation of the internationalization of high education and the key index of undergraduate teaching evaluation. Based on the modified Colin Baker model and the questionnaire of two universities in...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3 249; LDAB 573), published by Lobel in 1956, is so far the only papyrus fragment among those extant in Boeotian dialect1 whose authorship can be securely ascribed to Corinna thanks to the overlap...
Floer Simple Manifolds and L-Space Intervals
J Rasmussen, SD Rasmussen
Feb 26, 2018
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Frank L. Horsfall, Jr., 1952
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections. Lecture delivered November 20, 1952 Posted with permission
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Experimental analysis of the V-Charge variable drive supercharger system on a 1.0 L GTDI engine

A compound charging system that pairs a turbocharger with a supercharger seems to be a potential trend for future passenger car gasoline engines, as the strength of both could be enhanced and the deficiencies of each could be...

Hunger Drives Hysterical Action in Newest Shakespeare Carolina Production
Winthrop University
Jan 01, 0001
Show times are 8 p.m. July 16-18 and July 22-25. Truffaldino is hungry. That's the driving force behind Carlo Goldoni's "The Servant of Two Masters," translated and adapted by Jeffery Hatcher and Paolo Landi. Shakespeare...
Published by: Winthrop University
Dr. Herman L. Frick Promotion
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Published by: Winthrop University
Experimental analysis of the V-Charge variable drive supercharger system on a 1.0 L GTDI engine

A compound charging system that pairs a turbocharger with a supercharger seems to be a potential trend for future passenger car gasoline engines, as the strength of both could be enhanced and the deficiencies of each could be...

The r -Hunter–Saxton equation, smooth and singular solutions and their approximation
Abstract: In this work we introduce the r-Hunter–Saxton equation, a generalisation of the Hunter–Saxton equation arising as extremals of an action principle posed in L r . We characterise solutions to the Cauchy problem...

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