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LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
Julia Zinngrebe, Eva Rieser, Lucia Taraborrelli, Nieves Peltzer, Torsten Hartwig, Hongwei Ren, Ildikó Kovács, Cornelia Endres, Peter Draber, Maurice Darding, Silvia von Karstedt, Johannes Lemke, Balazs Dome, Michael Bergmann, Brian J Ferguson, Henning Walczak
Aug 16, 2017
Animals Cell Death Death Domain Receptor Signaling Adaptor Proteins Dermatitis Gene Silencing Host-Pathogen Interactions Humans Immunologic Deficiency Syndromes Inflammation Influenza A virus Keratinocytes Mice Nerve Tissue Proteins Poly I-C Signal Transduction Toll-Like Receptor 3 Transcription Factors Ubiquitin-Protein Ligases
Of Cell Shapes and Motion
Motile cells have developed a variety of migration modes relying on diverse traction-force-generation mechanisms. Before the behavior of intracellular components could be easily imaged, cell movements were mostly classified by...
Spatial variations in leaching of a low-grade, low-porosity chalcopyrite ore identified using X-ray μCT
© 2017 Elsevier LtdThis study presents an investigation, using 3D X-ray micro computed tomography (μCT), into the effect of sulfide mineral position within an ore particle on leaching efficiency. Three sections of an unsaturated...
Mobile Learning to Support Computational Thinking in Initial Teacher Education
Research on the role of mobile learning in computational thinking is limited, and even more so in its use in initial teacher education. Aligned to this there is a need to consider how to introduce and expose pre-service teachers...
Published by: IGI Global Scientific Publishing
Fishing for complementarities
Academics are increasingly encouraged to acquire external grants to finance their research, and often hold grants from multiple funders concurrently to ensure the continuity of their work. However, there are concerns that...
Nanostructure of the deep eutectic solvent/platinum electrode interface as a function of potential and water content
Oliver S. Hammond, Hua Li, Christian Westermann, Azhar Y. M. Al-murshedi, Frank Endres, Andrew P. Abbott, Gregory G. Warr, Karen J. Edler, Rob Atkin
Jan 01, 2019
The interfacial nanostructure of the three most widely-studied Deep Eutectic Solvents (DESs), choline chloride:urea (ChCl:Urea), choline chloride:ethylene glycol (ChCl:EG), and choline chloride:glycerol (ChCl:Gly) at a Pt(111)...
Nanostructure of the deep eutectic solvent/platinum electrode interface as a function of potential and water content
Oliver S. Hammond, Hua Li, Christian Westermann, Azhar Y. M. Al-murshedi, Frank Endres, Andrew P. Abbott, Gregory G. Warr, Karen J. Edler, Rob Atkin
Jan 01, 2019
The interfacial nanostructure of the three most widely-studied Deep Eutectic Solvents (DESs), choline chloride:urea (ChCl:Urea), choline chloride:ethylene glycol (ChCl:EG), and choline chloride:glycerol (ChCl:Gly) at a Pt(111)...
International research visits and careers
This paper investigates the effect of international research visits on promotion. Research visits may help to expand existing networks and promote knowledge transfer while at the same time ensuring career stability, identified...
Towards co-designing active ageing strategies
BACKGROUND: Physical activity levels decline in later life despite the known benefits for physical, cognitive and mental health. Older people find it difficult to meet activity targets; therefore, more realistic and meaningful...
International research visits and careers
This paper investigates the effect of international research visits on promotion. Research visits may help to expand existing networks and promote knowledge transfer while at the same time ensuring career stability, identified...
Fishing for complementarities
Academics are increasingly encouraged to acquire external grants to finance their research, and often hold grants from multiple funders concurrently to ensure the continuity of their work. However, there are concerns that...
The double-edged sword of industry collaboration
This paper studies the impact of university-industry collaboration on academic research output. We analyze the channels through which the degree of industry collaboration may be affecting research output. We exploit a unique...
Basic vs. applied research Industry-science links Research collaboration /dk/atira/pure/subjectarea/asjc/2200/2200 name=General Engineering /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research
Negotiating multisectoral evidence
Abstract
Background
For the prevention and control of chronic diseases, two strategies are frequently highlighted: that public health should be evidence based, and that it should...
The double-edged sword of industry collaboration
This paper studies the impact of university-industry collaboration on academic research output. We analyze the channels through which the degree of industry collaboration may be affecting research output. We exploit a unique...
Basic vs. applied research Industry-science links Research collaboration /dk/atira/pure/subjectarea/asjc/2200/2200 name=General Engineering /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research
Barriers and facilitators to physical activity amongst overweight and obese women in an Afro-Caribbean population
Imprints from idea origin on innovation and the development environment
This study builds on the evolutionary and organization literatures to explore how the nature of innovation outcomes was influenced by the innovation’s original idea and the environment in which it was developed. We use data from...
Effect of Solution pH on the Dual Role of Dissolved Organic Matter in Sensitized Pollutant Photooxidation
Dissolved organic matter (DOM) has a dual role in indirect phototransformations of aquatic contaminants by acting both as a photosensitizer and an inhibitor. Herein, the pH dependence of the inhibitory effect of DOM and the...
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