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DJ-1
Federica De Lazzari, Hiran A Prag, Anja V Gruszczyk, Alexander J Whitworth, Marco Bisaglia
Apr 16, 2021
DJ-1 is a multifaceted protein with pleiotropic functions that has been implicated in multiple diseases, ranging from neurodegeneration to cancer and ischemia-reperfusion injury. Ischemia is a complex pathological state arising...
The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration.
Mariaelena Repici, Mahdieh Hassanjani, Daniel C Maddison, Pedro Garção, Sara Cimini, Bhavini Patel, Éva M Szegö, Kornelis R Straatman, Kathryn S Lilley, Tiziana Borsello, Tiago F Outeiro, Lia Panman, Flaviano Giorgini
Mar 25, 2019
Mutations in the gene encoding DJ-1 are associated with autosomal recessive forms of Parkinson's disease (PD). DJ-1 plays a role in protection from oxidative stress, but how it functions as an "upstream" oxidative stress sensor...
DJ-1 and SOD1 Act Independently in the Protection against Anoxia in Drosophila melanogaster.
Federica De Lazzari, Francesco Agostini, Davide Doni, Sandro Malacrida, Mauro A Zordan, Paola Costantini, Luigi Bubacco, Federica Sandrelli, Marco Bisaglia
Sep 25, 2022
Redox homeostasis is a vital process the maintenance of which is assured by the presence of numerous antioxidant small molecules and enzymes and the alteration of which is involved in many pathologies, including several...
DJ-1 and SOD1 Act Independently in the Protection against Anoxia in Drosophila melanogaster.
Federica De Lazzari, Francesco Agostini, Davide Doni, Sandro Malacrida, Mauro A Zordan, Paola Costantini, Luigi Bubacco, Federica Sandrelli, Marco Bisaglia
Aug 06, 2022
Redox homeostasis is a vital process the maintenance of which is assured by the presence of numerous antioxidant small molecules and enzymes and the alteration of which is involved in many pathologies, including several...
Hydrocarbons Are Essential for Optimal Cell Size, Division, and Growth of Cyanobacteria.
DJ Lea-Smith, ML Ortiz-Suarez, T Lenn, DJ Nürnberg, LL Baers, MP Davey, L Parolini, RG Huber, CAR Cotton, G Mastroianni, P Bombelli, P Ungerer, TJ Stevens, AG Smith, PJ Bond, CW Mullineaux, CJ Howe
Dec 08, 2016
Campus Mourns Death of Long-time Employee Sir Lawrence Darby
Winthrop University
Jan 01, 0001
Sir Lawrence Darby, a custodian who worked at the Winthrop Coliseum, passed away on Sunday, Oct. 23, from injuries sustained in a car accident. Darby was very active with the Samaritan's Feet project involving Winthrop's...
Published by: Winthrop University
The Grizzly, February 10, 1984
Perry Romer, Barbara A. Mathers, Richard P. Richter, Brad James, Kurt Richter, Andrea Butler, Timothy Lyden, Michael Walsh, Mark Krauss, John Callahan, Brian E. Kelley
Jan 01, 0001
Guards Receive Training Internships for Credit Alcoholism: Prime Health Problem Businessman to Share Experiences Fish Find a Home China in the 20th Century Television Forum Presented DJ Spotlight on...Ed Johns Two...
Ursinus College Collegeville Pennsylvania newspaper campus security Internships Gerard Fitzpatrick Alcoholism Kenneth H. Williams Warren V. Musser Ed Johns Eugene Miller Charles Gibson Beatles wrestling Basketball gymnastics cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.
Neringa Jurkute, Costin Leu, Hans-Martin Pogoda, Gavin Arno, Anthony G Robson, Gudrun Nürnberg, Janine Altmüller, Holger Thiele, Susanne Motameny, Mohammad Reza Toliat, Kate Powell, Wolfgang Höhne, Michel Michaelides, Andrew R Webster, Anthony T Moore, Matthias Hammerschmidt, Peter Nürnberg, Patrick Yu-Wai-Man, Marcela Votruba
Jul 26, 2019
OBJECTIVE: Autosomal dominant optic atrophy (ADOA) starts in early childhood with loss of visual acuity and color vision deficits. OPA1 mutations are responsible for the majority of cases, but in a portion of patients with a...
Embracing Monogenic Parkinson's Disease
Eva-Juliane Vollstedt, Susen Schaake, Katja Lohmann, Shalini Padmanabhan, Alexis Brice, Suzanne Lesage, Christelle Tesson, Marie Vidailhet, Isabel Wurster, Faycel Hentati, Anat Mirelman, Nir Giladi, Karen Marder, Cheryl Waters, Stanley Fahn, Meike Kasten, Norbert Brüggemann, Max Borsche, Tatiana Foroud, Eduardo Tolosa, Alicia Garrido, Grazia Annesi, Monica Gagliardi, Maria Bozi, Leonidas Stefanis, Joaquim J Ferreira, Leonor Correia Guedes, Micol Avenali, Simona Petrucci, Lorraine Clark, Ekaterina Y Fedotova, Natalya Y Abramycheva, Victoria Alvarez, Manuel Menéndez-González, Silvia Jesús Maestre, Pilar Gómez-Garre, Pablo Mir, Andrea Carmine Belin, Caroline Ran, Chin-Hsien Lin, Ming-Che Kuo, David Crosiers, Zbigniew K Wszolek, Owen A Ross, Joseph Jankovic, Kenya Nishioka, Manabu Funayama, Jordi Clarimon, Caroline H Williams-Gray, Marta Camacho, Mario Cornejo-Olivas, Luis Torres-Ramirez, Yih-Ru Wu, Guey-Jen Lee-Chen, Ana Morgadinho, Teeratorn Pulkes, Pichet Termsarasab, Daniela Berg, Gregor Kuhlenbäumer, Andrea A Kühn, Friederike Borngräber, Giuseppe de Michele, Anna De Rosa, Alexander Zimprich, Andreas Puschmann, George D Mellick, Jolanta Dorszewska, Jonathan Carr, Rosangela Ferese, Stefano Gambardella, Bruce Chase, Katerina Markopoulou, Wataru Satake, Tatsushi Toda, Malco Rossi, Marcelo Merello, Timothy Lynch, Diana A Olszewska, Shen-Yang Lim, Azlina Ahmad-Annuar, Ai Huey Tan, Bashayer Al-Mubarak, Hasmet Hanagasi, Dariusz Koziorowski, Sibel Ertan, Gençer Genç, Patricia de Carvalho Aguiar, Melinda Barkhuizen, Marcia MG Pimentel, Rachel Saunders-Pullman, Bart van de Warrenburg, Susan Bressman, Mathias Toft, Silke Appel-Cresswell, Anthony E Lang, Matej Skorvanek, Agnita JW Boon, Rejko Krüger, Esther M Sammler, Vitor Tumas, Bao-Rong Zhang, Gaetan Garraux, Sun Ju Chung, Yun Joong Kim, Juliane Winkelmann, Carolyn M Sue, Eng-King Tan, Joana Damásio, Péter Klivényi, Vladimir S Kostic, David Arkadir, Mika Martikainen, Vanderci Borges, Jens Michael Hertz, Laura Brighina, Mariana Spitz, Oksana Suchowersky, Olaf Riess, Parimal Das, Brit Mollenhauer, Emilia M Gatto, Maria Skaalum Petersen, Nobutaka Hattori, Ruey-Meei Wu, Sergey N Illarioshkin, Enza Maria Valente, Jan O Aasly, Anna Aasly, Roy N Alcalay, Avner Thaler, Matthew J Farrer, Kathrin Brockmann, Jean-Christophe Corvol, Christine Klein, MJFF Global Genetic Parkinson's Disease Study Group
Jan 24, 2023
BACKGROUND: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the...
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Kathrin Pieper, Joshua Tan, Luca Piccoli, Mathilde Foglierini, Sonia Barbieri, Yiwei Chen, Chiara Silacci-Fregni, Tobias Wolf, David Jarrossay, Marica Anderle, Abdirahman Abdi, Francis M Ndungu, Ogobara K Doumbo, Boubacar Traore, Tuan M Tran, Said Jongo, Isabelle Zenklusen, Peter D Crompton, Claudia Daubenberger, Peter C Bull, Federica Sallusto, Antonio Lanzavecchia
Dec 13, 2017
In two previously described donors, the extracellular domain of LAIR1, a collagen-binding inhibitory receptor encoded on chromosome 19 (ref. 1), was inserted between the V and DJ segments of an antibody. This insertion...
Antibodies Protozoan Antigens Protozoan B-Lymphocytes Blood Donors Erythrocytes Europe Female Genes Immunoglobulin Heavy Chain Humans Immunoglobulin Heavy Chains Immunoglobulin Switch Region Immunologic Memory Introns Malaria Male Mutagenesis Insertional Plasmodium falciparum Protein Domains Receptors Immunologic Templates Genetic VDJ Exons
Milsom's Legal History
DJ Ibbetson
Jun 15, 2017
Toby Milsom was the most original English legal historian of the twentieth century. This paper gives a preliminary assessment of the importance of his work. charting the ways in which it has changed our thinking about the subject.
Atomic clusters with addressable complexity
DJ Wales
Mar 29, 2017
A general formulation for constructing addressable atomic clusters is introduced, based on one or more reference structures. By modifying the well depths in a given interatomic potential in favour of nearest-neighbour...
‘Standards of Scrutiny in Judicial Review of Deportation Decisions Involving Article 3, ECHR –X.X. v Minister for Justice and Equality’
DJ Coffey
Aug 11, 2017
On the 24th of June 2016 Humphreys J., sitting in the High Court, dismissed two judicial review applications that challenged a decision of the Minister for Justice and Equality to deport a Jordanian national. The Applicant –who...
Resonances in Coupled-Channel Scattering
DJ Wilson
Mar 08, 2017
Continuity and Change in the Luba Christian Movement, Katanga, Belgian Congo c.1915-50
DJ Maxwell
Mar 31, 2017
This article studies the Christian movement that occurred amongst the Luba of Katanga, Belgian Congo, from about 1915 to 1950, paying particular attention to how it was received by different social categories and mediated by...
Photoluminescence efficiency of zincblende InGaN/GaN quantum wells
SA Church, M Quinn, K Cooley-Greene, B Ding, A Gundimeda, MJ Kappers, M Frentrup, DJ Wallis, RA Oliver, DJ Binks
May 10, 2021
Growing green and amber emitting InGaN/GaN quantum wells in the zincblende, rather than the wurtzite, crystal phase has the potential to improve efficiency. However, optimization of the emission efficiency of these...
Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia.
Peter Huppke, Eike Wegener, Jonathan Gilley, Carlo Angeletti, Ingo Kurth, Joost PH Drenth, Christine Stadelmann, Alonso Barrantes-Freer, Wolfgang Brück, Holger Thiele, Peter Nürnberg, Jutta Gärtner, Giuseppe Orsomando, Michael P Coleman
May 20, 2019
We identified a homozygous missense mutation in the gene encoding NAD synthesizing enzyme NMNAT2 in two siblings with childhood onset polyneuropathy with erythromelalgia. No additional homozygotes for this rare allele, which...
Excited and exotic bottomonium spectroscopy from lattice QCD
We explore the spectrum of excited and exotic bottomonia using lattice QCD.
Highly excited states are identified with masses up to 11,000 MeV, many of
which can be grouped into supermultiplets matching those of the quark...
Exploiting Sequence-Dependent Rotamer Information in Global Optimization of Proteins.
Rotamers, namely amino acid side chain conformations common to many different peptides, can be compiled into libraries. These rotamer libraries are used in protein modeling, where the limited conformational space occupied by...
Energy Landscapes, Self-Assembly and Viruses
DJ Wales
Oct 03, 2017
Machine learning prediction for classification of outcomes in local minimisation
Machine learning schemes are employed to predict which local minimum will result from local energy minimisation of random starting configurations for a triatomic cluster. The input data consists of structural information at one...
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