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DJ-1
Federica De Lazzari, Hiran A Prag, Anja V Gruszczyk, Alexander J Whitworth, Marco Bisaglia
Apr 16, 2021
DJ-1 is a multifaceted protein with pleiotropic functions that has been implicated in multiple diseases, ranging from neurodegeneration to cancer and ischemia-reperfusion injury. Ischemia is a complex pathological state arising...
The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration.
Mariaelena Repici, Mahdieh Hassanjani, Daniel C Maddison, Pedro Garção, Sara Cimini, Bhavini Patel, Éva M Szegö, Kornelis R Straatman, Kathryn S Lilley, Tiziana Borsello, Tiago F Outeiro, Lia Panman, Flaviano Giorgini
Mar 25, 2019
Mutations in the gene encoding DJ-1 are associated with autosomal recessive forms of Parkinson's disease (PD). DJ-1 plays a role in protection from oxidative stress, but how it functions as an "upstream" oxidative stress sensor...
DJ-1 and SOD1 Act Independently in the Protection against Anoxia in Drosophila melanogaster.
Federica De Lazzari, Francesco Agostini, Davide Doni, Sandro Malacrida, Mauro A Zordan, Paola Costantini, Luigi Bubacco, Federica Sandrelli, Marco Bisaglia
Sep 25, 2022
Redox homeostasis is a vital process the maintenance of which is assured by the presence of numerous antioxidant small molecules and enzymes and the alteration of which is involved in many pathologies, including several...
Effort and Moral Worth
Kelly Sorensen
Jan 01, 0001
One of the factors that contributes to an agent's praiseworthiness and blameworthiness -- his or her moral worth -- is effort. On the one hand, agents who act effortlessly seem to have high moral worth. On the other hand, agents...
Published by: Ursinus College
DJ-1 and SOD1 Act Independently in the Protection against Anoxia in Drosophila melanogaster.
Federica De Lazzari, Francesco Agostini, Davide Doni, Sandro Malacrida, Mauro A Zordan, Paola Costantini, Luigi Bubacco, Federica Sandrelli, Marco Bisaglia
Aug 06, 2022
Redox homeostasis is a vital process the maintenance of which is assured by the presence of numerous antioxidant small molecules and enzymes and the alteration of which is involved in many pathologies, including several...
The Net Worth Trap
This paper investigates investment and output dynamics in a simple continuous time setting, showing that financing constraints substantially alter the relationship between net worth and the decisions of an optimizing firm. In...
Moral Worth and Moral Knowledge
Paulina Sliwa
Aug 05, 2019
To have moral worth an action not only needs to conform to the correct normative theory (whatever it is); it also needs to be motivated in the right way. I argue that morally worthy actions are motivated by the rightness of the...
Parental conditional regard and the development of perfectionism in adolescent athletes
Thomas Curran
Aug 01, 2018
Despite evidence highlighting the debilitating nature of perfectionism in sport, few studies have examined how it develops. In explaining the development of perfectionism, theorists emphasize controlling parental practices in...
Parental conditional regard and the development of perfectionism in adolescent athletes
Thomas Curran
Aug 01, 2018
Despite evidence highlighting the debilitating nature of perfectionism in sport, few studies have examined how it develops. In explaining the development of perfectionism, theorists emphasize controlling parental practices in...
Taming the Lion
Contrary to conventional wisdom, there is little empirical evidence that elevated power, by default, fuels conflict and aggression. Instead, previous studies have shown that extraneous factors that decrease powerholders'...
Campus Mourns Death of Long-time Employee Sir Lawrence Darby
Winthrop University
Jan 01, 0001
Sir Lawrence Darby, a custodian who worked at the Winthrop Coliseum, passed away on Sunday, Oct. 23, from injuries sustained in a car accident. Darby was very active with the Samaritan's Feet project involving Winthrop's...
Published by: Winthrop University
The Grizzly, February 10, 1984
Perry Romer, Barbara A. Mathers, Richard P. Richter, Brad James, Kurt Richter, Andrea Butler, Timothy Lyden, Michael Walsh, Mark Krauss, John Callahan, Brian E. Kelley
Jan 01, 0001
Guards Receive Training Internships for Credit Alcoholism: Prime Health Problem Businessman to Share Experiences Fish Find a Home China in the 20th Century Television Forum Presented DJ Spotlight on...Ed Johns Two...
Ursinus College Collegeville Pennsylvania newspaper campus security Internships Gerard Fitzpatrick Alcoholism Kenneth H. Williams Warren V. Musser Ed Johns Eugene Miller Charles Gibson Beatles wrestling Basketball gymnastics cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Maturational timing, physical self-perceptions and physical activity in UK adolescent females
Sean Cumming, Deirdre M Harrington, Melanie Davies, Charlotte Edwardson, Trish Gorely, Kamlesh Khunti, Alex V Rowlands, Thomas Yates, Lauren Sherar
Dec 31, 2020
Background Advanced (early) biological maturation may be a risk factor for inactivity among adolescent girls. Aim To test the mediational effects of body attractiveness and physical self-worth on the relationship between...
Service supply chain resilience
Purpose: Considering the last-mile delivery service supply chain as a social-ecological system rather than just a firm-based service system, this research exploit the COVID-19 pandemic disruption to investigate how the supply...
Last-mile delivery Service supply chain resilience Social-ecological perspective /dk/atira/pure/subjectarea/asjc/1800/1800 name=General Decision Sciences /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Counterfactual Situations and Moral Worth
Kelly Sorensen
Jan 01, 0001
What is the relevance to praiseworthiness and blameworthiness of what one would have done in other, counterfactual circumstances? I defend a moderate form of actualism: what one would have done is important, but less so than...
Published by: Ursinus College
Service supply chain resilience
Purpose: Considering the last-mile delivery service supply chain as a social-ecological system rather than just a firm-based service system, this research exploit the COVID-19 pandemic disruption to investigate how the supply...
Last-mile delivery Service supply chain resilience Social-ecological perspective /dk/atira/pure/subjectarea/asjc/1800/1800 name=General Decision Sciences /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Maturational timing, physical self-perceptions and physical activity in UK adolescent females
Sean Cumming, Deirdre M Harrington, Melanie Davies, Charlotte Edwardson, Trish Gorely, Kamlesh Khunti, Alex V Rowlands, Thomas Yates, Lauren Sherar
Dec 31, 2020
Background Advanced (early) biological maturation may be a risk factor for inactivity among adolescent girls. Aim To test the mediational effects of body attractiveness and physical self-worth on the relationship between...
The visual and semantic features that predict object memory
Mariam Hovhannisyan, Alex Clarke, Benjamin R. Geib, Rosalie Cicchinelli, Zachary Monge, Tory Worth, Amanda Szymanski, Roberto Cabeza, Simon W. Davis
Aug 02, 2021
Abstract: Humans have a remarkable fidelity for visual long-term memory, and yet the composition of these memories is a longstanding debate in cognitive psychology. While much of the work on long-term memory has focused on...
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the most common of which is the non-synonymous single...
STRUCTURE HOMOLOGY RECOGNITION PREDICTION AMINO-ACID SUBSTITUTION BINDING SURFACES DATABASE LARGE-SCALE NON-SYNONYMOUS SNPS PROTEIN STABILITY CHANGES SINGLE NUCLEOTIDE POLYMORPHISMS SUPPORT VECTOR MACHINES
Published by: BMC BIOINFORMATICS
An Emoji Is Worth a Thousand Words
Face emojis are regularly used in reviews on online shopping sites to add richness and/or levity to the text. However, few researchers have investigated the use of face emojis in consumer reviews. This paper examined the effects...
Published by: IGI Global Scientific Publishing
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