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The evolving view of the hematopoietic stem cell niche.
Hematopoietic stem cells (HSCs) reside in specialized microenvironments known as niches. The niche is essential to support HSC function and to maintain a correct balance between self-renewal and differentiation. Recent advances...
Distal Pancreatectomy with Celiac Axis Resection
Giuseppe Nigri, Niccolò Petrucciani, Elena Belloni, Alessio Lucarini, Paolo Aurello, Francesco D'Angelo, Salomone Di Saverio, Alessandro Fancellu, Giovanni Ramacciato
Apr 21, 2021
BACKGROUND: Major vascular invasion represents one of the most frequent reasons to consider pancreatic adenocarcinomas unresectable, although in the last decades, demolitive surgeries such as distal pancreatectomy with celiac...
Island-Matrix Inhomogeneous Deformation Behavior, Formation of Deformation Band, and BUT Forming of DP Steel
Islands-Matrix-Dual-phase (I-M-DP) steel is received a great deal attention for better concern with the emissivity, fuel consumption and passengers safety. A number of deformation plasticity issues are yet to be fully...
Published by: IGI Global Scientific Publishing
Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.
Sasha R Howard, Leonardo Guasti, Ariel Poliandri, Alessia David, Claudia P Cabrera, Michael R Barnes, Karoliina Wehkalampi, Stephen O'Rahilly, Catherine E Aiken, Anthony P Coll, Marcella Ma, Debra Rimmington, Giles SH Yeo, Leo Dunkel
Feb 05, 2018
CONTEXT: Self-limited delayed puberty (DP) is often associated with a delay in physical maturation, but although highly heritable the causal genetic factors remain elusive. Genome-wide association studies of the timing of...
Methodology for the analysis and comparison of protocols for glycaemic control in intensive care.
Rocío Fernández-Méndez, Sancho Rodríguez-Villar, Pablo F Méndez, Richard Windle, Gary George Adams
Feb 18, 2019
RATIONALE, AIMS, AND OBJECTIVES: The practice of glycaemic control of critically ill patients admitted to intensive care units (ICUs) is guided by clinical management protocols, designed locally by the ICUs. These protocols...
Relationship between fiducial points on the peripheral and central blood pressure waveforms
Ye Li, Antoine Guilcher, Peter H Charlton, Samuel Vennin, Jordi Alastruey, Phil Chowienczyk
Mar 01, 2021
Central systolic blood pressure (cSBP, the peak of the central waveform) is usually regarded as the determinant of peripheral systolic blood pressure with amplification of peripheral systolic blood pressure (pSBP) measured with...
central pressure left ventricular contractility peripheral pressure Adult Aged Arterial Pressure arteries Blood Pressure Determination Case-Control Studies Computer Simulation Female Humans Hypertension Male Middle Aged Models Cardiovascular Numerical analysis Computer-Assisted Predictive Value of Tests Systole Time Factors Ventricular Function Left
Addressing Noise and Class Imbalance Problems in Heterogeneous Cross-Project Defect Prediction
When a software project either lacks adequate historical data to build a defect prediction (DP) model or is in the initial phases of development, the DP model based on related source project's defect data might be used. This...
Published by: IGI Global Scientific Publishing
The Standard Model quiver in de Sitter string compactifications
We argue that the Standard Model quiver can be embedded into compact
Calabi-Yau geometries through orientifolded D3-branes at del Pezzo
singularities $\mathrm{dP}_n$ with $n\geq 5$ in a framework including moduli
stabilisation....
HSCs revive their niche after transplantation.
Simón Méndez-Ferrer
Dec 11, 2020
Golan K, Singh AK et al.1 describe how mitochondrial transfer from hematopoietic stem cells (HSCs) to bone marrow (BM) mesenchymal stem cells (MSCs) helps to regenerate the stroma and its capacity to sustain hematopoietic...
Production of fermentable species by microwave-assisted hydrothermal treatment of biomass carbohydrates
This work addresses and compares the production of fermentable species by microwave-assisted hydrothermal treatment of cellulose and hemicellulose (from lignocellulose) and alginic acid (from macroalgae). A reliable...
Production of fermentable species by microwave-assisted hydrothermal treatment of biomass carbohydrates
This work addresses and compares the production of fermentable species by microwave-assisted hydrothermal treatment of cellulose and hemicellulose (from lignocellulose) and alginic acid (from macroalgae). A reliable...
Fast Nonparametric Clustering of Structured Time-Series.
In this publication, we combine two Bayesian nonparametric models: the Gaussian Process (GP) and the Dirichlet Process (DP). Our innovation in the GP model is to introduce a variation on the GP prior which enables us to model...
Molecular interactome between HSCs and their niches.
Simón Méndez-Ferrer
Nov 18, 2019
Because hematopoietic stem cells (HSCs) were found to require a bone marrow (BM) habitat for long-term function, many studies have attempted to dissect key cellular and molecular interactions between HSCs and their BM...
Nuclearity of Hankel operators for ultradifferentiable control systems
Mark Opmeer
Nov 01, 2008
Nuclearity of the Hankel operator is a known sufficient condition for convergence of Lyapunov-balanced truncations. We show how a previous result on nuclearity of Hankel operators of systems with an analytic semigroup can be...
Cellular Heterogeneity of Mesenchymal Stem/Stromal Cells in the Bone Marrow
Mesenchymal stem/stromal cells (MSCs) are present in various body tissues and help in maintaining homeostasis. The stemness of MSCs has been evaluated in vitro. In addition, analyses of cell surface antigens and gene expression...
Neuronal regulation of bone marrow stem cell niches.
The bone marrow (BM) is the primary site of postnatal hematopoiesis and hematopoietic stem cell (HSC) maintenance. The BM HSC niche is an essential microenvironment which evolves and responds to the physiological demands of...
Human and mouse leukocytes
Simón Méndez-Ferrer
Mar 19, 2018
In this issue of Blood, Zhao et al use a humanized mouse model to investigate the mechanisms driving daily oscillations in circulating human and murine leukocytes.1 In the same mice, they find human and murine circulating...
Nuclearity of Hankel operators for ultradifferentiable control systems
Mark Opmeer
Nov 01, 2008
Nuclearity of the Hankel operator is a known sufficient condition for convergence of Lyapunov-balanced truncations. We show how a previous result on nuclearity of Hankel operators of systems with an analytic semigroup can be...
Cardioprotection by 6-gingerol in diabetic rats
Hany M. El-Bassossy, Ahmed A. Elberry, Salah A. Ghareib, Ahmad Azhar, Zainey Mohammed Banjar, Malcolm L Watson
Sep 02, 2016
The current study was conducted to evaluate the effect of 6-gingerol (6G) on cardiac complications in streptozotocin (STZ)-induced diabetic (DM) rats. STZ-induced DM rats (single 50 mg/kg i.p. injection, 15 days prior to drug...
Cardioprotection by 6-gingerol in diabetic rats
Hany M. El-Bassossy, Ahmed A. Elberry, Salah A. Ghareib, Ahmad Azhar, Zainey Mohammed Banjar, Malcolm L Watson
Sep 02, 2016
The current study was conducted to evaluate the effect of 6-gingerol (6G) on cardiac complications in streptozotocin (STZ)-induced diabetic (DM) rats. STZ-induced DM rats (single 50 mg/kg i.p. injection, 15 days prior to drug...
Microenvironmental contributions to hematopoietic stem cell aging.
Hematopoietic stem cell (HSC) aging was originally thought to be essentially an HSC-autonomous process, which is the focus of another review in the same issue of Haematologica However, studies on the microenvironment that...
Cellular Heterogeneity of Mesenchymal Stem/Stromal Cells in the Bone Marrow.
Mesenchymal stem/stromal cells (MSCs) are present in various body tissues and help in maintaining homeostasis. The stemness of MSCs has been evaluated in vitro. In addition, analyses of cell surface antigens and gene expression...
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