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Results: 5226
Development and External Validation of Prediction Models for 10-Year Survival of Invasive Breast Cancer. Comparison with PREDICT and CancerMath.
Purpose: To compare PREDICT and CancerMath, two widely used prognostic models for invasive breast cancer, taking into account their clinical utility. Furthermore, it is unclear whether these models could be improved.Experimental...
Interview with Paul Krassner
Paul Krassner
Jan 01, 0001
In his July 1992 interview with Ron Chepesiuk, Paul Krassner described his time as an anti-war activist during the 1960s and his current work. Krassner covered topics of satire, drugs, other activists, the Chicago Conspiracy...
satire The Realist (Krassner's magazine) acid Chicago Conspiracy Trial Jerry Rubin Abbie Hoffman The Winner of the Slow Bicycle Race FBI conspiracies and involvement Freedom of Information Act Harry Reasoner levitating the Pentagon counterculture LSD Groucho Marx Venice Beach Hustler (magazine) investigative satire America's Youth March on the Democratic Convention Horowitz and Collier journalism taboos Lenny Bruce Kennedy conspiracy Oral History
Published by: Winthrop University
Meta-analysis confirms BCL2 is an independent prognostic marker in breast cancer.
BACKGROUND: A number of protein markers have been investigated as prognostic adjuncts in breast cancer but their translation into clinical practice has been impeded by a lack of appropriate validation. Recently, we showed that...
Bare Nouns in the Typology of DPs
Ileana Paul
Aug 01, 2013
This paper investigates two types of bare nouns in Malagasy: bare nouns in possessor raising contexts and bare noun objects. It is argued that these two types are structurally distinct. In possessor raising, the bare noun is in...
Published by: Atlantic Provinces Linguistic Association
Evidence of a Causal Association Between Cancer and Alzheimer's Disease
Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer
IMPORTANCE: The age-based or "one-size-fits-all" breast screening approach does not take into account the individual variation in risk. Mammography screening reduces death from breast cancer at the cost of overdiagnosis....
The effect of rare variants on inflation of the test statistics in case-control analyses.
Paul Nurse, 1996
The Rockefeller University
Jan 01, 0001
Paul Nurse. The central role of a CDK in controlling the fission yeast cell cycle
Posted with permission
Published by: Wiley-Liss, Inc.
FAREWELL TO PAUL NURSE
The Rockefeller University
Jan 01, 0001
A campus-wide celebration to honor those individuals who have won major awards and to say farewell to Paul Nurse
Published by: The Rockefeller University
Bare Nouns in the Typology of DPs
Ileana Paul
Aug 01, 2013
This paper investigates two types of bare nouns in Malagasy: bare nouns in possessor raising contexts and bare noun objects. It is argued that these two types are structurally distinct. In possessor raising, the bare noun is in...
Published by: Atlantic Provinces Linguistic Association
Interview with Paul Van Buren Hatten - VHP 001
Paul Van Buren Hatten
Jan 01, 0001
In his January 19, 2004 interview with Lee Q. Miller, Paul Van Buren Hatten explains how he entered the service during WWII and became a ball gunner for the Air Force. Hatten recalls basic training, his first mission, and the...
Published by: Winthrop University
Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction.
Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable component. The different histotypes of invasive disease - high grade serous, clear cell, endometrioid and mucinous - are associated with different...
Paul Weiss, 1959
The Rockefeller University
Jan 01, 0001
Paul Weiss. The biological foundations of wound repair.
Lecture delivered October 15, 1959
Posted with permission
Published by: Academic Press
Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer
Marina Pavanello, Isaac HY Chan, Amir Ariff, Paul DP Pharoah, Simon A. Gayther, Susan J. Ramus
Oct 20, 2020
A family history of ovarian or breast cancer is the strongest risk factor for epithelial ovarian cancer (EOC). Germline deleterious variants in the BRCA1 and BRCA2 genes confer EOC risks by age 80, of 44% and 17% respectively....
Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer.
Marina Pavanello, Isaac HY Chan, Amir Ariff, Paul DP Pharoah, Simon A Gayther, Susan J Ramus
Jan 08, 2021
A family history of ovarian or breast cancer is the strongest risk factor for epithelial ovarian cancer (EOC). Germline deleterious variants in the BRCA1 and BRCA2 genes confer EOC risks by age 80, of 44% and 17% respectively....
Polygenic risk-tailored screening for prostate cancer
Tom Callender, Mark Emberton, Steve Morris, Ros Eeles, Zsofia Kote-Jarai, Paul DP Pharoah, Nora Pashayan
Feb 07, 2020
BACKGROUND: The United States Preventive Services Task Force supports individualised decision-making for prostate-specific antigen (PSA)-based screening in men aged 55-69. Knowing how the potential benefits and harms of...
Genomic risk prediction of coronary artery disease in women with breast cancer
Lathan Liou, Stephen Kaptoge, Joe Dennis, Mitul Shah, Jonathan Tyrer, Michael Inouye, Douglas F Easton, Paul DP Pharoah
Sep 05, 2021
BACKGROUND: Advancements in cancer therapeutics have resulted in increases in cancer-related survival; however, there is a growing clinical dilemma. The current balancing of survival benefits and future cardiotoxic harms of...
Breast Cancer cardiovascular disease Coronary Artery Disease coronary heart disease polygenic risk score SEARCH Breast Neoplasms Cancer Survivors Coronary Artery Disease Female Genome-Wide Association Study Genomics Genotype Humans Incidence Middle Aged Multifactorial Inheritance Proportional Hazards Models Prospective Studies Risk Factors United Kingdom
Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer.
Gordon C Wishart, Emad Rakha, Andrew Green, Ian Ellis, Hamid Raza Ali, Elena Provenzano, Fiona M Blows, Carlos Caldas, Paul DP Pharoah
Nov 19, 2014
‘Sins’ in Paul
SJ Gathercole
Aug 15, 2017
A familiar feature in Pauline scholarship is the view that Sin as a power, and the concomitant forces of the flesh and death, are the dominant elements in Paul's account of the human plight. The present article seeks not to deny...
Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
Siddhartha P Kar, Hermann Brenner, Graham G Giles, Dezheng Huo, Roger L Milne, Gad Rennert, Jacques Simard, Wei Zheng, Stephen Burgess, Paul DP Pharoah
Apr 15, 2019
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