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Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer.
Rachael E Clifford, Naren Govindarajah, David Bowden, Paul Sutton, Mark Glenn, Mahnaz Darvish-Damavandi, Simon Buczacki, Ultan McDermott, Zdzislaw Szulc, Besim Ogretmen, Jason L Parsons, Dale Vimalachandran
Jan 05, 2021
Previous work utilizing proteomic and immunohistochemical analyses has identified that high levels of acid ceramidase (AC) expression confers a poorer response to neoadjuvant treatment in locally advanced rectal cancer. We aimed...
Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer
Rachael E. Clifford, Naren Govindarajah, David Bowden, Paul Sutton, Mark Glenn, Mahnaz Darvish-Damavandi, Simon Buczacki, Ultan McDermott, Zdzislaw Szulc, Besim Ogretmen, Jason L. Parsons, Dale Vimalachandran
Dec 22, 2020
Previous work utilizing proteomic and immunohistochemical analyses has identified that high levels of acid ceramidase (AC) expression confers a poorer response to neoadjuvant treatment in locally advanced rectal cancer. We aimed...
Alumna's Scholarship Supports Women Pursuing Degrees in Math, Sciences
Winthrop University
Jan 01, 0001
Sadie Livingston Boyer '58 and her husband, Dale, have established the Sadie Livingston Boyer - Dale Boyer Endowed Scholarship Fund to encourage young women pursuing careers in math and science. Boyer, herself a former...
Published by: Winthrop University
Review of Dale M. Schlitt, German Idealism’s Trinitarian Legacy. Albany, NY
Sean J. McGrath
Jan 08, 2019
In this follow up to several detailed studies of Hegel’s philosophy of religion, Dale Schlitt takes a decidedly Schellingian turn. German Idealism’s Trinitarian Legacies is as much about the Trinitarian thought of the late...
Published by: Memorial University of Newfoundland
Review of Dale M. Schlitt, German Idealism’s Trinitarian Legacy. Albany, NY
Sean J. McGrath
Jan 08, 2019
In this follow up to several detailed studies of Hegel’s philosophy of religion, Dale Schlitt takes a decidedly Schellingian turn. German Idealism’s Trinitarian Legacies is as much about the Trinitarian thought of the late...
Published by: Memorial University of Newfoundland
Donor Sadie Boyer '58 Connects with Late Professor's Family, Makes New Gifts to Fund
Winthrop University
Jan 01, 0001
Reconnecting with her late professor's family encouraged Boyer to give two new gifts totaling $26K to the Sadie Livingston Boyer - Dale Boyer Endowed Scholarship Fund. Boyer, a math major, had a successful 32-year career with...
Published by: Winthrop University
The Forgotten Wanderer
Dale Bridges
Jan 01, 0001
Artwork
Magazine Literary Magazine Arts Magazine art poetry prose Creative Nonfiction Photography Creative Writing Art and Design Photography
Published by: Winthrop University
Speculative Geology
Dale E. Snow
Dec 20, 2020
We are not at peace with nature now. Whether it is the record-setting rain on the east coast or the raging wildfires in the west, distant news of melting permafrost or bleaching coral reefs, or the unexpected eruption of Mount...
Published by: Memorial University Libraries
Speculative Geology
Dale E. Snow
Dec 20, 2020
We are not at peace with nature now. Whether it is the record-setting rain on the east coast or the raging wildfires in the west, distant news of melting permafrost or bleaching coral reefs, or the unexpected eruption of Mount...
Published by: Memorial University Libraries
Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells.
Intracellular Ca2+ and cAMP typically cause opposing effects on airway smooth muscle contraction. Receptors that stimulate these pathways are therapeutic targets in asthma and chronic obstructive pulmonary disease. However, the...
Airway smooth muscle Ca(2+) signaling Cyclic AMP Histamine Protein kinase A Spatial organization Adult Bronchi Calcium Signaling Cell Compartmentation Child Child Preschool Cyclic AMP Cyclic AMP-Dependent Protein Kinases Dinoprostone Histamine Humans Inositol 1 4 5-Trisphosphate Receptors Isoproterenol Myocytes Smooth Muscle Pertussis Toxin Receptors Prostaglandin E EP2 Subtype Receptors Prostaglandin E EP4 Subtype Type C Phospholipases
Analysis of Cellular Factors Involved in Adeno-Associated Virus Type 2 Entry
Cameron Dale Bess
Jan 01, 0001
The study of virus-host interactions has not only produced insights relevant to both preventative drug design and the emerging field of gene therapy, but it has also served as a valuable tool to the field of cell biology. The...
gene therapy virus-host interactions adeno-associated virus type 2 heparan sulfate proteoglycan Life Sciences
Published by: Rockefeller University
Pulse electroanalysis at gold-gold micro-trench electrodes
Bipotentiostatic control of micro-and nano-trench sensor systems provides new opportunities for enhancing signals (employing feedback currents) and for improved selectivity (by "chemical filtering"). In this study both phenomena...
Pulse electroanalysis at gold-gold micro-trench electrodes
Bipotentiostatic control of micro-and nano-trench sensor systems provides new opportunities for enhancing signals (employing feedback currents) and for improved selectivity (by "chemical filtering"). In this study both phenomena...
Shape-controlled electrodeposition of tin crystals from Sn(II)-fluoroborate solutions
The shape evolution of mesoscopic tin crystals electrodeposited on boron-doped diamond (BDD) substrates is described as a function of the ion concentration and deposition potential. Concentrations of 5-100 mM Sn(II) in 1 M...
Shape-controlled electrodeposition of tin crystals from Sn(II)-fluoroborate solutions
The shape evolution of mesoscopic tin crystals electrodeposited on boron-doped diamond (BDD) substrates is described as a function of the ion concentration and deposition potential. Concentrations of 5-100 mM Sn(II) in 1 M...
The role of pre-incident information and responder communication in effective management of casualties, including members of vulnerable groups, during a decontamination field exercise
Amelia Dennis, Dale Weston, Richard Amlôt, Andreas Arnold, Danielle Carbon, Holly Carter
Aug 31, 2023
During a CBRNe incident, it is essential that those affected are decontaminated as quickly as possible. Factors which may enhance the speed with which decontamination can be carried out include the provision of pre-incident...
Magnetization measurements and Ginzburg-Landau simulations of micron-size β-tin samples
We describe investigations of the largely unexplored field of mesoscopic type-I superconductors. Micromagnetometry and 3D Ginzburg-Landau simulations of our single crystal β-tin samples in this regime reveal size- and...
Magnetization measurements and Ginzburg-Landau simulations of micron-size β-tin samples
We describe investigations of the largely unexplored field of mesoscopic type-I superconductors. Micromagnetometry and 3D Ginzburg-Landau simulations of our single crystal β-tin samples in this regime reveal size- and...
The Ursinus Weekly, October 26, 1931
Grizzlies win over Muhlenberg 7-0: Miller scores in fifth straight victory; Charlie Soeder kicks another placement Senior class repeats "Children of the Moon" Mrs. Pinchot will relate South Sea adventures Ursinus hill-dale...
Ursinus College Collegeville Pennsylvania newspaper debate team YMCA YWCA Soccer field hockey Football cross country Gifford Pinchot cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Event-related potential response to auditory social stimuli, parent-reported social communicative deficits and autism risk in school-aged children with congenital visual impairment.
Communication with visual signals, like facial expression, is important in early social development, but the question if these signals are necessary for typical social development remains to be addressed. The potential impact on...
The Ursinus Weekly, December 13, 1973
John T. Fidler, David Ochocki, Jeanne Crandall, Richard Whaley, Judith James, Edmond Knowles, Alan Stetler, George Geist
Jan 01, 0001
J. Board reactivates; Tries first case in three years Service project going well as U.C. students aid area children Special correspondent tells tale of wonder and awe Mr. Xaras says art is necessary Nine Ursinus students...
Ursinus College Collegeville Pennsylvania newspaper Judiciary Board student government Ken-Crest Center Theodore A. Xaras W. McNeil Lowry Foundation for the Humanities and the Arts Thanksgiving women's hours open dorms ProTheatre Second shepherd's play Charles T. Sullivan Astrology Watergate Richard Nixon Basketball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The role of pre-incident information and responder communication in effective management of casualties, including members of vulnerable groups, during a decontamination field exercise
Amelia Dennis, Dale Weston, Richard Amlôt, Andreas Arnold, Danielle Carbon, Holly Carter
Aug 31, 2023
During a CBRNe incident, it is essential that those affected are decontaminated as quickly as possible. Factors which may enhance the speed with which decontamination can be carried out include the provision of pre-incident...
Rectal cancer management during the COVID-19 pandemic (ReCaP)
RE Clifford, D Harji, L Poynter, R Jackson, R Adams, NS Fearnhead, D Vimalachandran, ReCaP Steering Committee and Collaborators
Jun 07, 2021
Concerns over unacceptable high mortality in patients with rectal cancer undergoing surgery or systemic therapy who contract COVID-19 have led to widespread adoption of alternative treatment strategies.The ReCaP study aimed to...
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