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Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation.
Mitochondrial complex I powers ATP synthesis by oxidative phosphorylation, exploiting the energy from ubiquinone reduction by NADH to drive protons across the energy-transducing inner membrane. Recent cryo-EM analyses of...
Dr. Daniel F. Mahony Selected as President of Winthrop University
Winthrop University
Jan 01, 0001
Mahony will begin his duties on July 1, 2015. The President's House will be home to Mahony, his wife Laura and their two children, Gavin, 15, and Elena, 12. Dr. Daniel F. Mahony, dean of the College of Education, Health and...
Published by: Winthrop University
A conserved arginine residue is critical for stabilizing the N2 FeS cluster in mitochondrial complex I.
Mikhail A Hameedi, Daniel N Grba, Katherine H Richardson, Andrew JY Jones, Wei Song, Maxie M Roessler, John J Wright, Judy Hirst
May 17, 2021
Respiratory complex I (NADH:ubiquinone oxidoreductase), the first enzyme of the electron-transport chain, captures the free energy released by NADH oxidation and ubiquinone reduction to translocate protons across an...
Structural basis for a complex I mutation that blocks pathological ROS production.
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R Bridges, Hiran A Prag, Daniel N Grba, Carlo Viscomi, Andrew M James, Amin Mottahedin, Thomas Krieg, Michael P Murphy, Judy Hirst
Feb 17, 2021
Mitochondrial complex I is central to the pathological reactive oxygen species (ROS) production that underlies cardiac ischemia-reperfusion (IR) injury. ND6-P25L mice are homoplasmic for a disease-causing mtDNA point mutation...
Amino Acid Substitution Animals Cryoelectron Microscopy DNA Mitochondrial Disease Models Animal Disease Resistance Electron Transport Electron Transport Complex I Humans Isolated Heart Preparation Leucine Male Mice Mice Transgenic Mitochondria Mitochondrial Membranes Myocardial Reperfusion Injury NAD NADH Dehydrogenase Oxidation-Reduction Point Mutation Proline Reactive Oxygen Species
McShane on the Transformation of Botany
Daniel Mayer
Mar 16, 2022
Daniel Mayer, leadership educator and researcher into the epistemology of biology, has long reflected on the nature of organization, both of organisms and of organizations. This is the topic of his recently completed PhD...
Published by: Memorial University of Newfoundland
Structural basis for a complex I mutation that blocks pathological ROS production
A Comparative Analysis of Deep Learning Approaches for Network Intrusion Detection Systems (N-IDSs)
Recently, due to the advance and impressive results of deep learning techniques in the fields of image recognition, natural language processing and speech recognition for various long-standing artificial intelligence (AI) tasks...
Published by: IGI Global Scientific Publishing
N-terminomics reveals control of Arabidopsis seed storage proteins and proteases by the Arg/N-end rule pathway.
Hongtao Zhang, Lucy Gannon, Kirsty L Hassall, Michael J Deery, Daniel J Gibbs, Michael J Holdsworth, Renier AL van der Hoorn, Kathryn S Lilley, Frederica L Theodoulou
Nov 05, 2018
The N-end rule pathway of targeted protein degradation is an important regulator of diverse processes in plants but detailed knowledge regarding its influence on the proteome is lacking. To investigate the impact of the...
Arabidopsis thaliana TAILS N-end rule N-terminomics cruciferin Protease quantitative proteomics tandem mass tag (TMT) Amino Acid Sequence Arabidopsis Arabidopsis Proteins Arginine Endopeptidases Endosperm Gene Expression Regulation Plant Mutation Peptides Proteolysis Proteomics RNA Messenger Seed Storage Proteins Seedlings
Daring to Stretch toward the Ultimate Consummation
Daniel Helminiak
Mar 16, 2022
Daniel A. Helminiak is Emeritus Professor of Psychology, University of West Georgia. He holds PhDs in theology and psychology and has published widely in these fields and their applications to spirituality and sexuality. Among...
Published by: Memorial University of Newfoundland
McShane on the Transformation of Botany
Daniel Mayer
Mar 16, 2022
Daniel Mayer, leadership educator and researcher into the epistemology of biology, has long reflected on the nature of organization, both of organisms and of organizations. This is the topic of his recently completed PhD...
Published by: Memorial University of Newfoundland
Daring to Stretch toward the Ultimate Consummation
Daniel Helminiak
Mar 16, 2022
Daniel A. Helminiak is Emeritus Professor of Psychology, University of West Georgia. He holds PhDs in theology and psychology and has published widely in these fields and their applications to spirituality and sexuality. Among...
Published by: Memorial University of Newfoundland
Being Native American in Business
Daniel Daniel Stewart, Amy K. Verbos, Carolyn Birmingham, Stephanie L. Black, Joseph Gladstone
Jan 01, 2017
Tribally-owned American Indian enterprises provide a unique cross-cultural setting for emerging Native American business leaders. This paper examines the manner in which American Indian leaders negotiate the boundaries between...
Native American leadership authentic leadership collective identity American Indian culture international business leadership Business Administration management and Operations Indigenous Studies
Published by: Digital Commons @ Texas A&M University-San Antonio
Factorisation of 3d N = 4 twisted indices and the geometry of vortex moduli space
Abstract: We study the twisted indices of N = 4 supersymmetric gauge theories in three dimensions on spatial S2 with an angular momentum refinement. We demonstrate factorisation of the index into holomorphic blocks for the...
The neural basis of hot and cold cognition in depressed patients, unaffected relatives, and low-risk healthy controls
BACKGROUND: Modern cognitive neuropsychological models of depression posit that negatively biased emotional ("hot") processing confers risk for depression, while preserved executive function ("cold") cognition promotes...
The Merry Wives of Windsor
Daniel Gordon
Jan 01, 0001
The Merry Wives of Windsor A story of LUST, GREED, and DIRTY LAUNDRYBy William Shakespeare, adapted by Daniel Gordon.
Shakespeare's The Merry Wives of Windsor uses more prose than any of his other plays, for indeed, these...
William Shakespeare Shakespeare Carolina Acting Dramatic Literature, Criticism and Theory Literature in English, British Isles Performance Studies
Published by: Winthrop University
Review of Daniel P. Scheid, The Cosmic Common Good. Oxford University Press, 2016. 248 pages
Jared Call
Jan 07, 2019
Earth was moderately cooler last year, but not by much. 2017, additionally, was a year of record-breaking disasters for the United States. These disasters included devastating California wildfires, a trio of hurricanes, hail...
Published by: Memorial University of Newfoundland
Review of Daniel P. Scheid, The Cosmic Common Good. Oxford University Press, 2016. 248 pages
Jared Call
Jan 07, 2019
Earth was moderately cooler last year, but not by much. 2017, additionally, was a year of record-breaking disasters for the United States. These disasters included devastating California wildfires, a trio of hurricanes, hail...
Published by: Memorial University of Newfoundland
Being Native American in Business
Daniel Daniel Stewart, Amy K. Verbos, Carolyn Birmingham, Stephanie L. Black, Joseph Gladstone
Jan 01, 2017
Tribally-owned American Indian enterprises provide a unique cross-cultural setting for emerging Native American business leaders. This paper examines the manner in which American Indian leaders negotiate the boundaries between...
Native American leadership authentic leadership collective identity American Indian culture international business leadership Business Administration, Management, and Operations Indigenous Studies
Published by: Digital Commons @ Texas A&M University-San Antonio
Factorisation of 3d N = 4 twisted indices and the geometry of vortex moduli space
Abstract: We study the twisted indices of N = 4 supersymmetric gauge theories in three dimensions on spatial S2 with an angular momentum refinement. We demonstrate factorisation of the index into holomorphic blocks for the...
Non-Lorentzian SU(1, n) Spacetime Symmetry In Various Dimensions
We discuss non-Lorentzian Lagrangian field theories in $2n-1$ dimensions that
admit an $SU(1,n)$ spacetime symmetry which includes a scaling transformation.
These can be obtained by a conformal compactification of a...
Polar (In,Ga)N/GaN Quantum Wells
We present a detailed theoretical analysis of the electronic and optical properties of c-plane InGaN/GaN quantum-well structures with In contents ranging from 5% to 25%. Special attention is paid to the relevance of...
Exact properties of an integrated correlator in N = 4 SU( N ) SYM
Abstract: We present a novel expression for an integrated correlation function of four superconformal primaries in SU(N) N = 4 supersymmetric Yang-Mills (N = 4 SYM) theory. This integrated correlator, which is based on...
Being Native American in Business
Daniel Daniel Stewart, Amy K. Verbos, Carolyn Birmingham, Stephanie L. Black, Joseph Gladstone
Jan 01, 2017
Tribally-owned American Indian enterprises provide a unique cross-cultural setting for emerging Native American business leaders. This paper examines the manner in which American Indian leaders negotiate the boundaries between...
Native American leadership authentic leadership collective identity American Indian culture international business leadership Business Administration management and Operations Indigenous Studies
Published by: Digital Commons @ Texas A&M University-San Antonio
Factorisation of 3d N = 4 twisted indices and the geometry of vortex moduli space
We study the twisted indices of $\mathcal{N}=4$ supersymmetric gauge theories
in three dimensions on spatial $S^{2}$ with an angular momentum refinement. We
demonstrate factorisation of the index into holomorphic blocks for...
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