A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre
Matteo A. Molè,
Tim H. H. Coorens,
Marta N. Shahbazi,
Antonia Weberling,
Bailey A. T. Weatherbee,
Carlos W. Gantner,
Carmen Sancho-Serra,
Lucy Richardson,
Abbie Drinkwater,
Najma Syed,
Stephanie Engley,
Philip Snell,
Leila Christie,
Kay Elder,
Alison Campbell,
Simon Fishel,
Sam Behjati,
Roser Vento-Tormo,
Magdalena Zernicka-Goetz
Jun 17, 2021
Abstract: Following implantation, the human embryo undergoes major morphogenetic transformations that establish the future body plan. While the molecular events underpinning this process are established in mice, they remain...