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Results: 53
Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England
Objectives: To assess the potential impacts of successive lockdown-easing measures in England, at a point in the COVID-19 pandemic when community transmission levels were relatively high. Design: We developed a Bayesian model to...
Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England.
OBJECTIVES: To assess the potential impacts of successive lockdown-easing measures in England, at a point in the COVID-19 pandemic when community transmission levels were relatively high. DESIGN: We developed a Bayesian model to...
Long reads
Martin O Pollard, Deepti Gurdasani, Alexander J Mentzer, Tarryn Porter, Manjinder S Sandhu
Apr 10, 2019
In recent years long-read technologies have moved from being a niche and specialist field to a point of relative maturity likely to feature frequently in the genomic landscape. Analogous to next generation sequencing, the cost...
Covid-19 in the UK
Deepti Gurdasani, Christina Pagel, Martin McKee, Susan Michie, Trisha Greenhalgh, Kit Yates, Gabriel Scally, Hisham Ziauddeen
Aug 31, 2022
Key messages
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors.
Lucy Thorne, Angela Nalwoga, Alexander J Mentzer, Alexis de Rougemont, Myra Hosmillo, Emily Webb, Margaret Nampiija, Allan Muhwezi, Tommy Carstensen, Deepti Gurdasani, Adrian V Hill, Manj S Sandhu, Alison Elliott, Ian Goodfellow
Jul 25, 2018
BACKGROUND: Human noroviruses (HuNoVs) are a prominent cause of gastroenteritis, yet fundamental questions remain regarding epidemiology, diversity, and immunity in sub-Saharan African children. We investigated HuNoV...
Antibodies Viral Blood Group Antigens Caliciviridae Infections Child Preschool Cross-Sectional Studies Demography Disease Susceptibility Enzyme-Linked Immunosorbent Assay Female Fucosyltransferases Gastroenteritis genetic variation Genotype Humans Infant Infant Newborn Longitudinal Studies Male Norovirus Polymorphism Single Nucleotide Pregnancy Risk Factors Seroepidemiologic Studies Socioeconomic Factors Uganda
Covid-19 in the UK
Deepti Gurdasani, Christina Pagel, Martin McKee, Susan Michie, Trisha Greenhalgh, Kit Yates, Gabriel Scally, Hisham Ziauddeen
Aug 31, 2022
Key messages
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
Vaccinating adolescents against SARS-CoV-2 in England
Deepti Gurdasani, Samir Bhatt, Anthony Costello, Spiros Denaxas, Seth Flaxman, Trisha Greenhalgh, Stephen Griffin, Zoë Hyde, Aris Katzourakis, Martin McKee, Susan Michie, Oliver Ratmann, Stephen Reicher, Gabriel Scally, Christopher Tomlinson, Christian Yates, Hisham Ziauddeen, Christina Pagel
Jan 06, 2022
OBJECTIVE: To offer a quantitative risk-benefit analysis of two doses of SARS-CoV-2 vaccination among adolescents in England. SETTING: England. DESIGN: Following the risk-benefit analysis methodology carried out by the US...
Clinical Evidence-Based Practice non-clinical Paediatrics Public Health vaccination programmes Adolescent Adolescent Health Age Factors covid-19 COVID-19 Vaccines Child child health England Female Hospitalization Humans Incidence Intensive Care Units Male myocarditis Public Health risk SARS-CoV-2 Severity of Illness Index Treatment Outcome Vaccination Post-Acute COVID-19 Syndrome
Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.
Karoline Kuchenbaecker, Arthur Gilly, Daniel Suveges, Lorraine Southam, Olga Giannakopoulou, Britt Kilian, Emmanouil Tsafantakis, Maria Karaleftheri, Aliki-Eleni Farmaki, Deepti Gurdasani, Kousik Kundu, Manjinder S Sandhu, John Danesh, Adam Butterworth, Inês Barroso, George Dedoussis, Eleftheria Zeggini
Sep 17, 2022
Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.
Karoline Kuchenbaecker, Arthur Gilly, Daniel Suveges, Lorraine Southam, Olga Giannakopoulou, Britt Kilian, Emmanouil Tsafantakis, Maria Karaleftheri, Aliki-Eleni Farmaki, Deepti Gurdasani, Kousik Kundu, Manjinder S Sandhu, John Danesh, Adam Butterworth, Inês Barroso, George Dedoussis, Eleftheria Zeggini
Jan 28, 2022
Distinct genetic architectures and environmental factors associate with host response to the γ 2-herpesvirus infections
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O. Pollard, Alexander T. Dilthey, Alexander J. Mentzer, Vickie Marshall, Elena M. Cornejo Castro, Cristina Pomilla, Elizabeth H. Young, Gershim Asiki, Martin L. Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso
Jul 31, 2020
Abstract: Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish life-long infections and are associated with malignancies. Striking geographic variation in incidence and the fact that virus alone...
The transferability of lipid loci across African, Asian and European cohorts.
Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley, Anatoli Kamali, Gershim Asiki, Iona Y Millwood, Michael Holmes, Huaidong Du, Yu Guo, Meena Kumari, George Dedoussis, Liming Li, Zhengming Chen, Manjinder S Sandhu, Eleftheria Zeggini, Understanding Society Scientific Group
Oct 29, 2019
Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood lipids, a major cardiovascular risk factor, are shared across populations. Genetic correlations...
Distinct genetic architectures and environmental factors associate with host response to the γ 2-herpesvirus infections
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O. Pollard, Alexander T. Dilthey, Alexander J. Mentzer, Vickie Marshall, Elena M. Cornejo Castro, Cristina Pomilla, Elizabeth H. Young, Gershim Asiki, Martin L. Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso
Aug 02, 2021
Abstract: Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish life-long infections and are associated with malignancies. Striking geographic variation in incidence and the fact that virus alone...
Resource-Efficient VM Placement in the Cloud Environment Using Improved Particle Swarm Optimization
Fundamentally, a strategy considering the effective utilization of resources results in the better energy efficiency of the system. The aroused interest of users in cloud computing has led to an increased power consumption...
Published by: IGI Global Scientific Publishing
Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O Pollard, Alexander T Dilthey, Alexander J Mentzer, Vickie Marshall, Elena M Cornejo Castro, Cristina Pomilla, Elizabeth H Young, Gershim Asiki, Martin L Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso
Oct 02, 2020
Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish life-long infections and are associated with malignancies. Striking geographic variation in incidence and the fact that virus alone is...
Adolescent Adult Antibodies Viral Antigens Viral Capsid Proteins Coinfection Disease Resistance Epstein-Barr Virus Infections Epstein-Barr Virus Nuclear Antigens Female Gene Expression Genome-Wide Association Study HIV HLA-DQ alpha-Chains Henipavirus Infections Herpesvirus 4 Human Herpesvirus 8 Human Host-Pathogen Interactions Humans Incidence Male Middle Aged Rural Population Sarcoma Kaposi Uganda Urban Population
Evolution of Artificial Intelligence in Bone Fracture Detection
The objective of the paper is to present the techniques of Artificial Intelligence based on deep learning that can be applied to detect fractures in bones on X-rays. The paper comprises of discussions of various entities....
Published by: IGI Global Scientific Publishing
Significance of Non-Academic Parameters for Predicting Student Performance Using Ensemble Learning Techniques
The academic institutions are focusing more on improving the performance of students using various data mining techniques. Prediction models are designed to predict the performance of students at a very early stage so that...
Published by: IGI Global Scientific Publishing
The UK needs a sustainable strategy for COVID-19
Deepti Gurdasani, Laura Bear, Debby Bogaert, Rochelle A. Burgess, Reinhard Busse, Roberto Cacciola, Yves Charpak, Tim Colbourn, John Drury, Karl Friston, Valentino Gallo, Lynn Goldman, Trish Greenhalgh, Zoe Hyde, Krutika Kuppalli, Maimuna Majumder, Jose M. Martin-Moreno, Martin McKee, Susan Michie, Elias Mossialos, Ali Nouri, Christina Pagel, Dominic Pimenta, Saskia Popescu, Viola Priesemann, Angela L. Rasmussen, Stephen Reicher, Walter Ricciardi, Ken Rice, Joshua Silver, Tara C. Smith, Clare Wenham, Robert West, Gavin Yarney, Kit Yates, Hisham Ziauddeen
Dec 05, 2020
The UK is well into the second wave of COVID-19, with 60 051 lives lost to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to date, according to provisional data from the Office for National Statistics....
Effect of high blood lead levels on Serum calcium and phosphorus in patients exposed to lead
CM Bindu and Deepti Gupta
Jan 03, 2015
Lead (Pb2+) intoxication is a serious occupational disease that constitutes a major public health problem. In the present work we studied the effect of lead on calcium and phosphorus on two groups namely Cases and Control. Blood...
Published by: IJHS Medical Association
Effect of high blood lead levels on Serum calcium and phosphorus in patients exposed to lead
CM Bindu and Deepti Gupta
Jan 03, 2015
Lead (Pb2+) intoxication is a serious occupational disease that constitutes a major public health problem. In the present work we studied the effect of lead on calcium and phosphorus on two groups namely Cases and Control. Blood...
Published by: IJHS Medical Association
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