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Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation.
David Howett, Andrea Castegnaro, Katarzyna Krzywicka, Johanna Hagman, Deepti Marchment, Richard Henson, Miguel Rio, John A King, Neil Burgess, Dennis Chan
Jun 17, 2019
The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's disease, and as such identification of entorhinal cortex dysfunction may aid detection of the disease in its earliest stages....
Alzheimer’s disease Entorhinal Cortex mild cognitive impairment path integration virtual reality Aged Aged 80 and over Alzheimer Disease Amyloid beta-Peptides Biomarkers Cognitive Dysfunction Diagnosis Differential Early Diagnosis Entorhinal Cortex Female Humans Magnetic Resonance Imaging Male Middle Aged Neuropsychological Tests Sensitivity and Specificity virtual reality
Resource-Efficient VM Placement in the Cloud Environment Using Improved Particle Swarm Optimization
Fundamentally, a strategy considering the effective utilization of resources results in the better energy efficiency of the system. The aroused interest of users in cloud computing has led to an increased power consumption...
Published by: IGI Global Scientific Publishing
Evolution of Artificial Intelligence in Bone Fracture Detection
The objective of the paper is to present the techniques of Artificial Intelligence based on deep learning that can be applied to detect fractures in bones on X-rays. The paper comprises of discussions of various entities....
Published by: IGI Global Scientific Publishing
Significance of Non-Academic Parameters for Predicting Student Performance Using Ensemble Learning Techniques
The academic institutions are focusing more on improving the performance of students using various data mining techniques. Prediction models are designed to predict the performance of students at a very early stage so that...
Published by: IGI Global Scientific Publishing
Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England
Objectives: To assess the potential impacts of successive lockdown-easing measures in England, at a point in the COVID-19 pandemic when community transmission levels were relatively high. Design: We developed a Bayesian model to...
Effect of high blood lead levels on Serum calcium and phosphorus in patients exposed to lead
CM Bindu and Deepti Gupta
Jan 03, 2015
Lead (Pb2+) intoxication is a serious occupational disease that constitutes a major public health problem. In the present work we studied the effect of lead on calcium and phosphorus on two groups namely Cases and Control. Blood...
Published by: IJHS Medical Association
Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England.
OBJECTIVES: To assess the potential impacts of successive lockdown-easing measures in England, at a point in the COVID-19 pandemic when community transmission levels were relatively high. DESIGN: We developed a Bayesian model to...
Preferential Selection of Software Quality Models Based on a Multi-Criteria Decision-Making Approach
Software engineering mainly aims to produce software of good quality that is delivered on time and on budget. Software quality becomes an important concern for quantifying the performance of software attributes. The seminal...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
Optimal dimensionality reduction of Markov chains using graph transformation.
Markov chains can accurately model the state-to-state dynamics of a wide range of complex systems, but the underlying transition matrix is ill-conditioned when the dynamics feature a separation of timescales. Graph...
Effect of high blood lead levels on Serum calcium and phosphorus in patients exposed to lead
CM Bindu and Deepti Gupta
Jan 03, 2015
Lead (Pb2+) intoxication is a serious occupational disease that constitutes a major public health problem. In the present work we studied the effect of lead on calcium and phosphorus on two groups namely Cases and Control. Blood...
Published by: IJHS Medical Association
Voice Engagement Leading to Business Intelligence
There are multiple studies establishing the importance of Business Intelligence (BI), in the Big Data Analytics context. Voice is yet to be seen as a contributing channel. Voice enabled assistants are at the forefront of...
Published by: IGI Global Scientific Publishing
Covid-19 in the UK
Deepti Gurdasani, Christina Pagel, Martin McKee, Susan Michie, Trisha Greenhalgh, Kit Yates, Gabriel Scally, Hisham Ziauddeen
Aug 31, 2022
Key messages
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
Rare events and first passage time statistics from the energy landscape.
We analyze the probability distribution of rare first passage times corresponding to transitions between product and reactant states in a kinetic transition network. The mean first passage times and the corresponding rate...
An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid.
Marc de la Roche, Trevor J Rutherford, Deepti Gupta, Dmitry B Veprintsev, Barbara Saxty, Stefan M Freund, Mariann Bienz
Apr 03, 2019
Wnt/β-catenin signalling controls development and tissue homeostasis. Moreover, activated β-catenin can be oncogenic and, notably, drives colorectal cancer. Inhibiting oncogenic β-catenin has proven a formidable challenge. Here...
Abietanes Binding Sites Cell Line Tumor Colorectal Neoplasms Crystallography X-Ray HEK293 Cells HeLa Cells Humans Neoplasm Proteins Nuclear Magnetic Resonance Biomolecular Plant Extracts Proteasome Endopeptidase Complex Protein Stability Rosmarinus Signal Transduction Transcription Factors Wnt Proteins beta Catenin
High-Level fermentative production of Lactic acid from bread waste under Non-sterile conditions with a circular biorefining approach and zero waste discharge
Rylan Cox, Vivek Narisetty, Sanjay Nagarajan, Deepti Agrawal, Vivek V. Ranade, Konstantinos Salonitis, Joachim Venus, Vinod Kumar
Apr 01, 2022
Bread waste (BW) is a severe solid waste management problem in Europe. The current study demonstrates an environment-friendly solution by valorising BW into lactic acid (LA) and the corresponding solid residues generated during...
Acidic/Enzymatic hydrolysis Bacillus coagulans Biochemical methanation potential Bread waste Lactic Acid Non-sterile conditions /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1605 name=Organic Chemistry /dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_production name=SDG 12 - Responsible Consumption and Production
Long reads
Martin O Pollard, Deepti Gurdasani, Alexander J Mentzer, Tarryn Porter, Manjinder S Sandhu
Apr 10, 2019
In recent years long-read technologies have moved from being a niche and specialist field to a point of relative maturity likely to feature frequently in the genomic landscape. Analogous to next generation sequencing, the cost...
High-Level fermentative production of Lactic acid from bread waste under Non-sterile conditions with a circular biorefining approach and zero waste discharge
Rylan Cox, Vivek Narisetty, Sanjay Nagarajan, Deepti Agrawal, Vivek V. Ranade, Konstantinos Salonitis, Joachim Venus, Vinod Kumar
Apr 01, 2022
Bread waste (BW) is a severe solid waste management problem in Europe. The current study demonstrates an environment-friendly solution by valorising BW into lactic acid (LA) and the corresponding solid residues generated during...
Acidic/Enzymatic hydrolysis Bacillus coagulans Biochemical methanation potential Bread waste Lactic Acid Non-sterile conditions /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1605 name=Organic Chemistry /dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_production name=SDG 12 - Responsible Consumption and Production
A Secure IoT-Based Mutual Authentication for Healthcare Applications in Wireless Sensor Networks Using ECC
The role of wireless medical sensor networks (WMSNs) is very significant in healthcare applications of IoT. Online report generation and sharing the reports reduce the time and make the treatment of patients very fast. Here, the...
Published by: IGI Global Scientific Publishing
Individual Characteristics Associated with Active Travel in Low and High Income Groups in the UK.
Active travel (AT) has gained increasing attention as a way of addressing low levels of physical activity. However, little is known regarding the relationship between income and AT. The aim of this study was to investigate...
Covid-19 in the UK
Deepti Gurdasani, Christina Pagel, Martin McKee, Susan Michie, Trisha Greenhalgh, Kit Yates, Gabriel Scally, Hisham Ziauddeen
Aug 31, 2022
Key messages
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
Pandemic policy on children and schools reflected UK based scientific narratives that did not align with global scientific consensus
Government relied on evidence that downplayed the seriousness of covid-19...
The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors.
Lucy Thorne, Angela Nalwoga, Alexander J Mentzer, Alexis de Rougemont, Myra Hosmillo, Emily Webb, Margaret Nampiija, Allan Muhwezi, Tommy Carstensen, Deepti Gurdasani, Adrian V Hill, Manj S Sandhu, Alison Elliott, Ian Goodfellow
Jul 25, 2018
BACKGROUND: Human noroviruses (HuNoVs) are a prominent cause of gastroenteritis, yet fundamental questions remain regarding epidemiology, diversity, and immunity in sub-Saharan African children. We investigated HuNoV...
Antibodies Viral Blood Group Antigens Caliciviridae Infections Child Preschool Cross-Sectional Studies Demography Disease Susceptibility Enzyme-Linked Immunosorbent Assay Female Fucosyltransferases Gastroenteritis genetic variation Genotype Humans Infant Infant Newborn Longitudinal Studies Male Norovirus Polymorphism Single Nucleotide Pregnancy Risk Factors Seroepidemiologic Studies Socioeconomic Factors Uganda
Thrombolytic Enzymes of Microbial Origin
Deepti Diwan, Zeba Usmani, Minaxi Sharma, James W. Nelson, Vijay Kumar Thakur, Graham Christie, Gustavo Molina, Vijai Kumar Gupta
Oct 01, 2021
Enzyme therapies are attracting significant attention as thrombolytic drugs during the current scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various sources, the application of...
Mass infection is not an option
Deepti Gurdasani, John Drury, Trisha Greenhalgh, Stephen Griffin, Zubaida Haque, Zoë Hyde, Aris Katzourakis, Martin McKee, Susan Michie, Christina Pagel, Stephen D. Reicher, Alice Roberts, Robert West, Kit Yates, Hisham Ziauddeen
Jul 24, 2021
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