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Traumatic brain injury (TBI) triggers multiple pathobiological responses with differing onsets, magnitudes, and durations. Identifying the therapeutic window of individual pathologies is critical for successful pharmacological...
Influence of Blood-Brain Barrier Integrity on Brain Protein Biomarker Clearance in Severe Traumatic Brain Injury
Caroline Lindblad, David W Nelson, Frederick A Zeiler, Ari Ercole, Per Hamid Ghatan, Henrik von Horn, Mårten Risling, Mikael Svensson, Denes V Agoston, Bo-Michael Bellander, Eric Peter Thelin
Jan 31, 2020
Brain protein biomarker clearance to blood in traumatic brain injury (TBI) is not fully understood. The aim of this study was to analyze the effect that a disrupted blood-brain barrier (BBB) had on biomarker clearance. Seventeen...
A Role for RAS in V-CRK Transformation
Heidi Greulich
Jan 01, 0001
The v-Crk oncogene product, while possessing no intrinsic tyrosine kinase activity, causes an elevation in levels of cellular phosphotyrosine as it transforms chicken embryo fibroblasts (CEF). Because of this similarity to v-Src...
Published by: Rockefeller University
LITTLE v IN INUKTITUT
Bettina Spreng
Jul 30, 2013
This paper provides an in-depth examination of the distribution of the Antipassive morpheme -si- in Mittimatalik, a dialect of !nuktitut spoken in North Baffin. It is demonstrated that the occurrence of the overt Antipassive...
Published by: Atlantic Provinces Linguistic Association
LITTLE v IN INUKTITUT
Bettina Spreng
Jul 30, 2013
This paper provides an in-depth examination of the distribution of the Antipassive morpheme -si- in Mittimatalik, a dialect of !nuktitut spoken in North Baffin. It is demonstrated that the occurrence of the overt Antipassive...
Published by: Atlantic Provinces Linguistic Association
Interplay of Structural Disorder and Short Binding Elements in the Cellular Chaperone Function of Plant Dehydrin ERD14
Nikoletta Murvai, Lajos Kalmar, Bianka Szalaine Agoston, Beata Szabo, Agnes Tantos, Gyorgy Csikos, András Micsonai, József Kardos, Didier Vertommen, Phuong N. Nguyen, Nevena Hristozova, Andras Lang, Denes Kovacs, Laszlo Buday, Kyou-Hoon Han, Andras Perczel, Peter Tompa
Aug 08, 2020
Details of the functional mechanisms of intrinsically disordered proteins (IDPs) in living cells is an area not frequently investigated. Here, we dissect the molecular mechanism of action of an IDP in cells by detailed...
Interplay of Structural Disorder and Short Binding Elements in the Cellular Chaperone Function of Plant Dehydrin ERD14.
Nikoletta Murvai, Lajos Kalmar, Bianka Szalaine Agoston, Beata Szabo, Agnes Tantos, Gyorgy Csikos, András Micsonai, József Kardos, Didier Vertommen, Phuong N Nguyen, Nevena Hristozova, Andras Lang, Denes Kovacs, Laszlo Buday, Kyou-Hoon Han, Andras Perczel, Peter Tompa
Sep 01, 2020
Details of the functional mechanisms of intrinsically disordered proteins (IDPs) in living cells is an area not frequently investigated. Here, we dissect the molecular mechanism of action of an IDP in cells by detailed...
cell protection chaperone client protein in-cell NMR intrinsic structural disorder pre-structured motif Arabidopsis Arabidopsis Proteins Escherichia coli Heat-Shock Response Intrinsically Disordered Proteins Microbial Viability Microorganisms Genetically-Modified Molecular Chaperones Protein Binding Protein Domains Proteome
Structure and metallicity of phase V of hydrogen
B Monserrat, Neil D Drummond, Philip Dalladay-Simpson, Ross T Howie, Pablo Lopez Rios, Eugene Gregoryanz, Chris J Pickard, Richard J Needs
Oct 08, 2018
A new phase V of hydrogen was recently claimed in experiments above 325 GPa and 300 K. Due to the extremely small sample size at such record pressures the measurements were limited to Raman spectroscopy. The experimental data on...
Patel v Mirza
G Virgo
Nov 17, 2016
The decision of the Supreme Court in Patel v Mirza is now the leading case on the application of the defence of illegality to private law claims, which has resolved a controversy among the Justices of the Supreme Court as to...
Novel rhenium(V) nitride complexes with dithiocarbimate ligands
Joanne Perils, Fernando Cortezon-Tamarit, Navaratnarajah Kuganathan, Gabriele Kociok-Köhn, Jonathan R Dilworth, Sofia I. Pascu
Apr 24, 2018
The application of rhenium complexes as therapeutic agents in nuclear medicine has propelled research into the chemistry of these compounds. In our effort to develop and investigate new therapeutic radiopharmaceuticals based...
Amphoteric Colloids. V. The Influence of the Valency of Anions Upon the Physical Properties of Gelatin
Jacques Loeb
Jan 01, 0001
Jacques Loeb. Amphoteric colloids. V. The influence of the valency of anions upon the physical properties of gelatin
Reprinted from J. Gen.Physiol., 1919, 1(5):559-580
Published by: Rockefeller University
Professor Steven V Ley CBE FRS FMedSci
Steven V Ley
Sep 10, 2018
Professor Steven Ley is currently Professor of Chemistry and Director of Research at at the University of Cambridge. He is also a Fellow of Trinity College and was BP 1702 Professor of Chemistry for 21 years. Steve obtained his...
Novel rhenium(V) nitride complexes with dithiocarbimate ligands
Joanne Perils, Fernando Cortezon-Tamarit, Navaratnarajah Kuganathan, Gabriele Kociok-Köhn, Jonathan R Dilworth, Sofia I. Pascu
Apr 24, 2018
The application of rhenium complexes as therapeutic agents in nuclear medicine has propelled research into the chemistry of these compounds. In our effort to develop and investigate new therapeutic radiopharmaceuticals based...
The Abbreviated Science Anxiety Scale
Science anxiety refers to students' negative emotions about learning science. Across two studies, we investigated the psychometric properties of the newly developed Abbreviated Science Anxiety Scale (ASAS), which was adapted...
Common magnitude representation of fractions and decimals is task dependent.
Although several studies have compared the representation of fractions and decimals, no study has investigated whether fractions and decimals, as two types of rational numbers, share a common representation of magnitude. The...
No evidence for a core deficit in developmental dyscalculia or mathematical learning disabilities.
BACKGROUND: Two hypotheses were tested regarding the characteristics of children with mathematical learning disabilities (MLD): (a) that children with MLD would have a 'core deficit' in basic number processing skills; and (b)...
ERIC-PCR Analysis of the Clinical and Environmental strains of V. cholerae during 2013 Epidemic in Nigeria
Smith Stella, Nwaokorie Francisca, Awoderu Oluwatoyin, Bamidele Tajudeen, Akinsinde Kehinde, Ochoga Michael, Oladele David, Bamidele Moses, Fesobi Toun, Afocha Eberechukwu, Amoo Samuel, Ajayi Morakinyo, Atat Prince, Ogbonna Francisca, Nduaga Samuel, Idika Nneoma, Oparaugo Chinedu, Musa Adesola, Adeneye Adeniyi, Ijeh Margaret, Ujah Innocent
Nov 21, 2015
Background: Molecular markers are important tools in the monitoring of toxigenic strains of Vibrio cholerae in environmental and clinical samples.
Objectives: The study was aimed at determining the clinical and environmental...
Published by: IJHS Medical Association
Experimental analysis of the V-Charge variable drive supercharger system on a 1.0 L GTDI engine
Bo Hu, Sam Akehurst, Andrew G.J. Lewis, Pengfei Lu, Darren Millwood, Colin Copeland, Edward Chappell, Andrew De Freitas, James Shawe, Dave Burtt
Mar 01, 2018
A compound charging system that pairs a turbocharger with a supercharger seems to be a potential trend for future passenger car gasoline engines, as the strength of both could be enhanced and the deficiencies of each could be...
Delimiting the Continental Shelf Beyond 200 Nautical Miles at the International Court of Justice
M Lando
Aug 21, 2017
In both $\textit{Nicaragua v. Colombia}$ cases, the International Court of Justice upheld that international tribunals may delimit the continental shelf beyond 200 nautical miles prior to the establishment of the continental...
Polymorphism in M(H2PO2)3 (M = V, Al, Ga) compounds with the perovskite-related ReO3 structure.
Hayden A Evans, Zeyu Deng, Ines E Collings, Yue Wu, Jessica L Andrews, Kartik Pilar, Joshua M Tuffnell, Guang Wu, John Wang, Siân E Dutton, Paul D Bristowe, Ram Seshadri, Anthony K Cheetham
Feb 18, 2019
Trivalent metal hypophosphites with the general formula M(H2PO2)3 (M = V, Al, Ga) adopt the ReO3 structure, with each compound displaying two structural polymorphs. High-pressure synchrotron X-ray studies reveal a...
On the convergence of a regularization scheme for approximating cavitation solutions with prescribed cavity volume size
Let $\Omega\in\mathbb{R}^n$, $n=2,3$, be the region occupied by a hyperelastic body in its reference configuration. Let $E(\cdot)$ be the stored energy functional, and let $x_0$ be a flaw point in $\Omega$ (i.e., a point of...
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