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Results: 43
Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease
Uma V Mahajan, Vijay R Varma, Michael E Griswold, Chad T Blackshear, Yang An, Anup M Oommen, Sudhir Varma, Juan C Troncoso, Olga Pletnikova, Richard O'Brien, Timothy J Hohman, Cristina Legido-Quigley, Madhav Thambisetty
Jan 24, 2020
BACKGROUND: There is growing evidence that Alzheimer disease (AD) is a pervasive metabolic disorder with dysregulation in multiple biochemical pathways underlying its pathogenesis. Understanding how perturbations in metabolism...
Mobile Edge Computing Architecture Challenges, Applications, and Future Directions
In the current era of technology, the utilization of tablets and smart phones plays a major role in every situation. As the numbers of mobile users increase, the quality of service (QoS) and quality of experience (QoE) are...
Grid & High Performance Computing Computer Science and Information Technology High Performance Computing
Published by: IGI Global Scientific Publishing
Recalling visual serial order for verbal sequences.
We report three experiments in which participants performed written serial recall of visually presented verbal sequences with items varying in visual similarity. In Experiments 1 and 2 native speakers of Japanese recalled...
Global analysis of cytosine and adenine DNA modifications across the tree of life.
Sreejith Jayasree Varma, Enrica Calvani, Nana-Maria Grüning, Christoph B Messner, Nicholas Grayson, Floriana Capuano, Michael Mülleder, Markus Ralser
Jul 28, 2022
Interpreting the function and metabolism of enzymatic DNA modifications requires both position-specific and global quantities. Sequencing-based techniques that deliver the former have become broadly accessible, but analytical...
Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure.
Gabriel Piedrafita, Sreejith J Varma, Cecilia Castro, Christoph B Messner, Lukasz Szyrwiel, Julian L Griffin, Markus Ralser
Jan 05, 2022
The structure of the metabolic network is highly conserved, but we know little about its evolutionary origins. Key for explaining the early evolution of metabolism is solving a chicken-egg dilemma, which describes that enzymes...
Using conditional kernel density estimation for wind power density forecasting
Of the various renewable energy resources, wind power is widely recognized as one of the most promising. The management of wind farms and electricity systems can benefit greatly from the availability of estimates of the...
Using conditional kernel density estimation for wind power density forecasting
Of the various renewable energy resources, wind power is widely recognized as one of the most promising. The management of wind farms and electricity systems can benefit greatly from the availability of estimates of the...
Effect of RNA silencing suppression activity of chrysanthemum virus B p12 protein on small RNA species.
Ramesh R Vetukuri, Pruthvi B Kalyandurg, Ganapathi Varma Saripella, Diya Sen, Jose Fernando Gil, Nina I Lukhovitskaya, Laura J Grenville-Briggs, Eugene I Savenkov
Oct 26, 2020
Chrysanthemum virus B encodes a multifunctional p12 protein that acts as a transcriptional activator in the nucleus and as a suppressor of RNA silencing in the cytoplasm. Here, we investigated the impact of p12 on accumulation...
SOX2 Regulates P63 and Stem/Progenitor Cell State in the Corneal Epithelium.
Swarnabh Bhattacharya, Laura Serror, Eshkar Nir, Dalbir Dhiraj, Anna Altshuler, Maroun Khreish, Beatrice Tiosano, Peleg Hasson, Lia Panman, Chen Luxenburg, Daniel Aberdam, Ruby Shalom-Feuerstein
Mar 21, 2019
Mutations in key transcription factors SOX2 and P63 were linked with developmental defects and postnatal abnormalities such as corneal opacification, neovascularization, and blindness. The latter phenotypes suggest that SOX2 and...
DIFFERENTIATION Ectoderm Limbal epithelial cells Limbal stem cell microRNA Stem Cells Alkaloids Animals Cell Differentiation Cell Proliferation Epithelium Corneal Mice NIH 3T3 Cells Piperidines SOXB1 Transcription Factors Signal Transduction Stem Cells Trans-Activators Transcription Factors Tumor Suppressor Proteins
A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia
Pierre-Emmanuel Morange, Franck Peiretti, Lenaick Gourhant, Carole Proust, Omar Soukarieh, Anne-Sophie Pulcrano-Nicolas, Ganapathi-Varma Saripella, Luca Stefanucci, Romaric Lacroix, Manal Ibrahim-Kosta, Catherine A Lemarié, Mattia Frontini, Marie-Christine Alessi, David-Alexandre Trégouët, Francis Couturaud
Jan 29, 2021
Rare variants outside the classical coagulation cascade might cause inherited thrombosis. We aimed to identify the variant(s) causing venous thromboembolism (VTE) in a family with multiple relatives affected with unprovoked VTE...
Adult Endothelial Cells Female Genetic Predisposition to Disease HEK293 Cells Humans Lipoproteins Male Microtubule-Associated Proteins Middle Aged Mutation Pedigree Plasminogen Activator Inhibitor 1 Protein Serine-Threonine Kinases Risk Factors Thrombophilia venous thromboembolism venous thrombosis Exome Sequencing
Nolz1 expression is required in dopaminergic axon guidance and striatal innervation
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana SH Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre, Sinéad C Corr, Gavin McManus, Dylan Ryan, Howard T Jacobs, Marten Szibor, Ramnik J Xavier, Thomas Braun, Christian Frezza, Michael P Murphy, Luke A O'Neill
Nov 22, 2017
Activated macrophages undergo metabolic reprogramming, which drives their pro-inflammatory phenotype, but the mechanistic basis for this remains obscure. Here, we demonstrate that upon lipopolysaccharide (LPS) stimulation...
immunometabolism innate immunity macrophage reverse electron transport Succinate Succinate Dehydrogenase Toll-Like Receptors Adenosine Triphosphate Animals Carbonyl Cyanide m-Chlorophenyl Hydrazone Citric Acid Cycle Glycolysis Hypoxia-Inducible Factor 1 alpha Subunit Inflammation Interleukin-10 Lipopolysaccharides Macrophage Activation MACROPHAGES Malonates Membrane potential Mitochondrial Mice Mice Inbred C57BL Mitochondria Mitochondrial Proteins Oxidation-Reduction Oxidative Phosphorylation Oxidoreductases Plant Proteins Reactive Oxygen Species Sequence Analysis RNA Succinate Dehydrogenase Succinic Acid Transcriptome
Nolz1 expression is required in dopaminergic axon guidance and striatal innervation.
Clement Soleilhavoup, Marco Travaglio, Kieran Patrick, Pedro Garção, Elangovan Boobalan, Youri Adolfs, Ruth V Spriggs, Emma Moles-Garcia, Dalbir Dhiraj, Tony Oosterveen, Sarah L Ferri, Ted Abel, Edward S Brodkin, R Jeroen Pasterkamp, Brian P Brooks, Lia Panman
Jun 19, 2021
Animals Axon guidance Axons Carbocyanines Corpus Striatum Dopaminergic Neurons Embryo Mammalian Female Fluorescent Dyes Intracellular Signaling Peptides and Proteins Intravital Microscopy Mice Knockout Microfluidic Analytical Techniques Microinjections Microscopy Confocal Nerve Net Nerve Tissue Proteins Tissue Culture Techniques
eLife's new model and its impact on science communication.
Lara Urban, Mariana De Niz, Florencia Fernández-Chiappe, Hedyeh Ebrahimi, Laura K M Han, Devang Mehta, Regina Mencia, Divyansh Mittal, Elizabeth Ochola, Carolina Paz Quezada, Facundo Romani, Lana Sinapayen, Andy Tay, Aalok Varma, Lamis Yahia Mohamed Elkheir
Jan 07, 2023
The eLife Early-Career Advisory Group discusses eLife's new peer review and publishing model, and how the whole process of scientific communication could be improved for the benefit of early-career researchers and the entire...
Peer review scientific publishing None Point of View Research Assessment Early-career Researchers Preprints communication
Published by: eLife
World Society for Virology first international conference
Maria Söderlund-Venermo, Anupam Varma, Deyin Guo, Douglas P Gladue, Emma Poole, Flor H Pujol, Hanu Pappu, Jesús L Romalde, Laura Kramer, Mariana Baz, Marietjie Venter, Matthew D Moore, Michael M Nevels, Sayeh Ezzikouri, Vikram N Vakharia, William C Wilson, Yashpal S Malik, Zhengli Shi, Ahmed S Abdel-Moneim
Jan 28, 2022
The ProtecT trial
Richard J Bryant, Jon Oxley, Grace J Young, Janet A Lane, Chris Metcalfe, Michael Davis, Emma L Turner, Richard M Martin, John R Goepel, Murali Varma, David F Griffiths, Ken Grigor, Nick Mayer, Anne Y Warren, Selina Bhattarai, John Dormer, Malcolm Mason, John Staffurth, Eleanor Walsh, Derek J Rosario, James WF Catto, David E Neal, Jenny L Donovan, Freddie C Hamdy, ProtecT study group
May 19, 2020
OBJECTIVE: To test the hypothesis that the baseline clinico-pathological features of the men with localized prostate cancer (PCa) included in the ProtecT (Prostate Testing for Cancer and Treatment) trial who progressed (n = 198)...
Development and validation of a universal blood donor genotyping platform
Nicholas S Gleadall, Barbera Veldhuisen, Jeremy Gollub, Adam S Butterworth, John Ord, Christopher J Penkett, Tiffany C Timmer, Carolin M Sauer, Nieke van der Bolt, Colin Brown, Kim Brugger, Alexander T Dilthey, Daniel Duarte, Shane Grimsley, Katja van den Hurk, John M Jongerius, Jessie Luken, Karyn Megy, Gail Miflin, Christopher S Nelson, Femmeke J Prinsze, Jennifer Sambrook, Ilenia Simeoni, Michael Sweeting, Nicole Thornton, Sara Trompeter, Salih Tuna, Ram Varma, Matthew R Walker, NIHR BioResource, John Danesh, David J Roberts, Willem H Ouwehand, Kathleen E Stirrups, Augusto Rendon, Connie M Westhoff, Emanuele Di Angelantonio, C Ellen van der Schoot, William J Astle, Nicholas A Watkins, William J Lane
Jun 17, 2020
The Lantern, 2015-2016
Blaise Laramee, Sarah Gow, Mara Koren, Adam Anderson, Madison Bradley, Sophia Gamber, Linden Hicks, Joshua Hoffman, Giselle Horrell, Alexander Kramer, Chi-e Low, Alexzandria Luben, Kevin Moore, Brian Thomas, Mayuko Todaka, Kara Travis, Solana Warner, Henry Willshire, Alyse Brewer, Kristen Costello, Rae Hodenfield, Jason Varma, Allison Arinaga, Brandon Carey, Faith Carson, Kevin Choice, Julia Crozier-Christy, Courtney Duchene, Ryan Ferguson, Lauren Geiger, Jada A Grice, Albert Hahn, Alexandra Hemp, Michael Heimbaugh, Darrah Hewlett, Jordan Hodess, Sean Kenny, Dana Kluchinski, Brian Leipold, Juan Lopez, Mary-Kate McGrath, Johnathan Myers, Temi Olafunmiloye, Valerie Osborne, Serena Schaefer, Nicolas Shandera, Emily Shue, Amanda Sierzega, Samantha Straughn, Paige Szmodis, Collin Takita, Kathryn Bormann, Sarah Defelice, Mario Heitman, '18, Mary A Holmcrans, Chukyi Kyaping, Morgan Larese, Andrew Tran
Jan 01, 0001
Ghosts Going to China 98% Guaranteed Constellation/Boulevard Prayer The Little One Burning The Amber Macaroon Becoming Requiem Construction Site Thirteen Ways of Looking at a Dragon Charlie No Sleep A...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Visual arts Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Linked electronic health records for research on a nationwide cohort of more than 54 million people in England
Angela Wood, Rachel Denholm, Sam Hollings, Jennifer Cooper, Samantha Ip, Venexia Walker, Spiros Denaxas, Ashley Akbari, Amitava Banerjee, William Whiteley, Alvina Lai, Jonathan Sterne, Cathie Sudlow, CVD-COVID-UK Consortium, Abdel Douiri, Abdul Qadr Akinoso-Imran, Adrian Jonas, Ajay Shah, Alex Handy, Alun Davies, Amanj Kurdi, Anna Hansell, Annemarie Docherty, Arun Pherwani, Ashkan Dashtban, Ben Bray, Ben Cairns, Ben Goldacre, Ben Humberstone, Bilal Mateen, Brett Doble, Brian Roberts, Carole Morris, Caroline Dale, Caroline Rogers, Charles Wolfe, Christopher Tomlinson, Claire Lawson, Clea du Toit, Colin Berry, Craig Smith, Dan O’Connell, Daniel Harris, David Brind, David Cromwell, David Hughes, David Moreno Martos, Debbie Ringham, Deborah Lawler, Deborah Lowe, Elena Nikiphorou, Eloise Withnell, Emanuele Di Angelantonio, Eva Morris, Ewan Birney, Fabian Falck, Fatemeh Torabi, Felix Greaves, Florian Falter, Francesco Zaccardi, Frank Kee, Gareth Davies, George Nicholson, Gwenetta Curry, Haoting Zhang, Harry Hemingway, Harry Wilde, Hoda Abbasizanjani, Honghan Wu, Howard Tang, Huan Wang, Ify Mordi, Jackie MacArthur, Jane Lyons, Jennifer Beveridge, Jessica Barrett, Jianhua Wu, Johan Thygesen, John Danesh, John Dennis, Jon Boyle, Julian Halcox, Kamlesh Khunti, Kate Cheema, Katherine Brown, Ken Li, Kim Kavanagh, Laura North, Laura Pasea, Libby Ellins, Livia Pierotti, Lucy Wright, Lydia Martin, Lynn Morrice, Mamas Mamas, Marion Bennie, Mark Barber, Mary Joan Macleod, Massimo Caputo, Maya Buch, Mehrdad Mizani, Michalis Katsoulis, Mike Gravenor, Mike Inouye, Mirek Skrypak, Moritz Gerstung, Munir Pirmohamed, Myer Glickman, Naomi Herz, Neil Davies, Nick Hall, Nilesh Samani, Olena Seminog, Paula Lorgelly, Pedro Machado, Qiuju Li, Raph Goldacre, Raymond Carragher, Reecha Sofat, Rohan Takhar, Ronan Lyons, Rouven Priedon, Rowena Griffiths, Rupert Payne, Ruwanthi Kolamunnage-Dona, Safa Salim, Sandosh Padmanabhan, Sarah Onida, Seamus Kent, Seb Bacon, Sinduja Manohar, Sonya Babu-Narayan, Spencer Keene, Susheel Varma, Thomas Lawrence, Tianxiao Wang, Tim Wilkinson, Tom Norris, Tom Palmer, Vahé Nafilyan
Apr 08, 2021
Abstract: Objective: To describe a novel England-wide electronic health record (EHR) resource enabling whole population research on covid-19 and cardiovascular disease while ensuring data security and privacy and maintaining...
Linked electronic health records for research on a nationwide cohort of more than 54 million people in England
Angela Wood, Rachel Denholm, Sam Hollings, Jennifer Cooper, Samantha Ip, Venexia Walker, Spiros Denaxas, Ashley Akbari, Amitava Banerjee, William Whiteley, Alvina Lai, Jonathan Sterne, Cathie Sudlow, CVD-COVID-UK Consortium, Abdel Douiri, Abdul Qadr Akinoso-Imran, Adrian Jonas, Ajay Shah, Alex Handy, Alun Davies, Amanj Kurdi, Anna Hansell, Annemarie Docherty, Arun Pherwani, Ashkan Dashtban, Ben Bray, Ben Cairns, Ben Goldacre, Ben Humberstone, Bilal Mateen, Brett Doble, Brian Roberts, Carole Morris, Caroline Dale, Caroline Rogers, Charles Wolfe, Christopher Tomlinson, Claire Lawson, Clea du Toit, Colin Berry, Craig Smith, Dan O’Connell, Daniel Harris, David Brind, David Cromwell, David Hughes, David Moreno Martos, Debbie Ringham, Deborah Lawler, Deborah Lowe, Elena Nikiphorou, Eloise Withnell, Emanuele Di Angelantonio, Eva Morris, Ewan Birney, Fabian Falck, Fatemeh Torabi, Felix Greaves, Florian Falter, Francesco Zaccardi, Frank Kee, Gareth Davies, George Nicholson, Gwenetta Curry, Haoting Zhang, Harry Hemingway, Harry Wilde, Hoda Abbasizanjani, Honghan Wu, Howard Tang, Huan Wang, Ify Mordi, Jackie MacArthur, Jane Lyons, Jennifer Beveridge, Jessica Barrett, Jianhua Wu, Johan Thygesen, John Danesh, John Dennis, Jon Boyle, Julian Halcox, Kamlesh Khunti, Kate Cheema, Katherine Brown, Ken Li, Kim Kavanagh, Laura North, Laura Pasea, Libby Ellins, Livia Pierotti, Lucy Wright, Lydia Martin, Lynn Morrice, Mamas Mamas, Marion Bennie, Mark Barber, Mary Joan Macleod, Massimo Caputo, Maya Buch, Mehrdad Mizani, Michalis Katsoulis, Mike Gravenor, Mike Inouye, Mirek Skrypak, Moritz Gerstung, Munir Pirmohamed, Myer Glickman, Naomi Herz, Neil Davies, Nick Hall, Nilesh Samani, Olena Seminog, Paula Lorgelly, Pedro Machado, Qiuju Li, Raph Goldacre, Raymond Carragher, Reecha Sofat, Rohan Takhar, Ronan Lyons, Rouven Priedon, Rowena Griffiths, Rupert Payne, Ruwanthi Kolamunnage-Dona, Safa Salim, Sandosh Padmanabhan, Sarah Onida, Seamus Kent, Seb Bacon, Sinduja Manohar, Sonya Babu-Narayan, Spencer Keene, Susheel Varma, Thomas Lawrence, Tianxiao Wang, Tim Wilkinson, Tom Norris, Tom Palmer, Vahé Nafilyan
Apr 09, 2021
Abstract: Objective: To describe a novel England-wide electronic health record (EHR) resource enabling whole population research on covid-19 and cardiovascular disease while ensuring data security and privacy and maintaining...
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Jennifer Wessel, Audrey Y Chu, Sara M Willems, Shuai Wang, Hanieh Yaghootkar, Jennifer A Brody, Marco Dauriz, Marie-France Hivert, Sridharan Raghavan, Leonard Lipovich, Bertha Hidalgo, Keolu Fox, Jennifer E Huffman, Ping An, Yingchang Lu, Laura J Rasmussen-Torvik, Niels Grarup, Margaret G Ehm, Li Li, Abigail S Baldridge, Alena Stančáková, Ravinder Abrol, Céline Besse, Anne Boland, Jette Bork-Jensen, Myriam Fornage, Daniel F Freitag, Melissa E Garcia, Xiuqing Guo, Kazuo Hara, Aaron Isaacs, Johanna Jakobsdottir, Leslie A Lange, Jill C Layton, Man Li, Jing Hua Zhao, Karina Meidtner, Alanna C Morrison, Mike A Nalls, Marjolein J Peters, Maria Sabater-Lleal, Claudia Schurmann, Angela Silveira, Albert V Smith, Lorraine Southam, Marcus H Stoiber, Rona J Strawbridge, Kent D Taylor, Tibor V Varga, Kristine H Allin, Najaf Amin, Jennifer L Aponte, Tin Aung, Caterina Barbieri, Nathan A Bihlmeyer, Michael Boehnke, Cristina Bombieri, Donald W Bowden, Sean M Burns, Yuning Chen, Yii-DerI Chen, Ching-Yu Cheng, Adolfo Correa, Jacek Czajkowski, Abbas Dehghan, Georg B Ehret, Gudny Eiriksdottir, Stefan A Escher, Aliki-Eleni Farmaki, Mattias Frånberg, Giovanni Gambaro, Franco Giulianini, William A Goddard, Anuj Goel, Omri Gottesman, Megan L Grove, Stefan Gustafsson, Yang Hai, Göran Hallmans, Jiyoung Heo, Per Hoffmann, Mohammad K Ikram, Richard A Jensen, Marit E Jørgensen, Torben Jørgensen, Maria Karaleftheri, Chiea C Khor, Andrea Kirkpatrick, Aldi T Kraja, Johanna Kuusisto, Ethan M Lange, IT Lee, Wen-Jane Lee, Aaron Leong, Jiemin Liao, Chunyu Liu, Yongmei Liu, Cecilia M Lindgren, Allan Linneberg, Giovanni Malerba, Vasiliki Mamakou, Eirini Marouli, Nisa M Maruthur, Angela Matchan, Roberta McKean-Cowdin, Olga McLeod, Ginger A Metcalf, Karen L Mohlke, Donna M Muzny, Ioanna Ntalla, Nicholette D Palmer, Dorota Pasko, Andreas Peter, Nigel W Rayner, Frida Renström, Ken Rice, Cinzia F Sala, Bengt Sennblad, Ioannis Serafetinidis, Jennifer A Smith, Nicole Soranzo, Elizabeth K Speliotes, Eli A Stahl, Kathleen Stirrups, Nikos Tentolouris, Anastasia Thanopoulou, Mina Torres, Michela Traglia, Emmanouil Tsafantakis, Sundas Javad, Lisa R Yanek, Eleni Zengini, Diane M Becker, Joshua C Bis, James B Brown, L Adrienne Cupples, Torben Hansen, Erik Ingelsson, Andrew J Karter, Carlos Lorenzo, Rasika A Mathias, Jill M Norris, Gina M Peloso, Wayne H-H Sheu, Daniela Toniolo, Dhananjay Vaidya, Rohit Varma, Lynne E Wagenknecht, Heiner Boeing, Erwin P Bottinger, George Dedoussis, Panos Deloukas, Ele Ferrannini, Oscar H Franco, Paul W Franks, Richard A Gibbs, Vilmundur Gudnason, Anders Hamsten, Tamara B Harris, Andrew T Hattersley, Caroline Hayward, Albert Hofman, Jan-Håkan Jansson, Claudia Langenberg, Lenore J Launer, Daniel Levy, Ben A Oostra, Christopher J O'Donnell, Stephen O'Rahilly, Sandosh Padmanabhan, James S Pankow, Ozren Polasek, Michael A Province, Stephen S Rich, Paul M Ridker, Igor Rudan, Matthias B Schulze, Blair H Smith, André G Uitterlinden, Mark Walker, Hugh Watkins, Tien Y Wong, Eleftheria Zeggini, EPIC-InterAct Consortium, Markku Laakso, Ingrid B Borecki, Daniel I Chasman, Oluf Pedersen, Bruce M Psaty, E Shyong Tai, Cornelia M van Duijn, Nicholas J Wareham, Dawn M Waterworth, Eric Boerwinkle, WH Linda Kao, Jose C Florez, Ruth JF Loos, James G Wilson, Timothy M Frayling, David S Siscovick, Josée Dupuis, Jerome I Rotter, James B Meigs, Robert A Scott, Mark O Goodarzi
Mar 24, 2015
Black People Blood Glucose Diabetes mellitus Type 2 Exome Fasting Genetic Association Studies Genetic Loci Genetic Predisposition to Disease genetic variation Glucagon-Like Peptide-1 Receptor Glucose-6-Phosphatase Humans Insulin Mutation Rate Oligonucleotide Array Sequence Analysis Polymorphism Single Nucleotide White People
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
David V Conti, Burcu F Darst, Lilit C Moss, Edward J Saunders, Xin Sheng, Alisha Chou, Fredrick R Schumacher, Ali Amin Al Olama, Sara Benlloch, Tokhir Dadaev, Mark N Brook, Ali Sahimi, Thomas J Hoffmann, Atushi Takahashi, Koichi Matsuda, Yukihide Momozawa, Masashi Fujita, Kenneth Muir, Artitaya Lophatananon, Peggy Wan, Loic Le Marchand, Lynne R Wilkens, Victoria L Stevens, Susan M Gapstur, Brian D Carter, Johanna Schleutker, Teuvo LJ Tammela, Csilla Sipeky, Anssi Auvinen, Graham G Giles, Melissa C Southey, Robert J Macinnis, Cezary Cybulski, Dominika Wokołorczyk, Jan Lubiński, David E Neal, Jenny L Donovan, Freddie C Hamdy, Richard M Martin, Børge G Nordestgaard, Sune F Nielsen, Maren Weischer, Stig E Bojesen, Martin Andreas Røder, Peter Iversen, Jyotsna Batra, Suzanne Chambers, Leire Moya, Lisa Horvath, Judith A Clements, Wayne Tilley, Gail P Risbridger, Henrik Gronberg, Markus Aly, Robert Szulkin, Martin Eklund, Tobias Nordström, Nora Pashayan, Alison M Dunning, Maya Ghoussaini, Ruth C Travis, Tim J Key, Elio Riboli, Jong Y Park, Thomas A Sellers, Hui-Yi Lin, Demetrius Albanes, Stephanie J Weinstein, Lorelei A Mucci, Edward Giovannucci, Sara Lindstrom, Peter Kraft, David J Hunter, Kathryn L Penney, Constance Turman, Catherine M Tangen, Phyllis J Goodman, Ian M Thompson, Robert J Hamilton, Neil E Fleshner, Antonio Finelli, Marie-Élise Parent, Janet L Stanford, Elaine A Ostrander, Milan S Geybels, Stella Koutros, Laura E Beane Freeman, Meir Stampfer, Alicja Wolk, Niclas Håkansson, Gerald L Andriole, Robert N Hoover, Mitchell J Machiela, Karina Dalsgaard Sørensen, Michael Borre, William J Blot, Wei Zheng, Edward D Yeboah, James E Mensah, Yong-Jie Lu, Hong-Wei Zhang, Ninghan Feng, Xueying Mao, Yudong Wu, Shan-Chao Zhao, Zan Sun, Stephen N Thibodeau, Shannon K McDonnell, Daniel J Schaid, Catharine ML West, Neil Burnet, Gill Barnett, Christiane Maier, Thomas Schnoeller, Manuel Luedeke, Adam S Kibel, Bettina F Drake, Olivier Cussenot, Géraldine Cancel-Tassin, Florence Menegaux, Thérèse Truong, Yves Akoli Koudou, Esther M John, Eli Marie Grindedal, Lovise Mæhle, Kay-Tee Khaw, Sue A Ingles, Mariana C Stern, Ana Vega, Antonio Gómez-Caamaño, Laura Fachal, Barry S Rosenstein, Sarah L Kerns, Harry Ostrer, Manuel R Teixeira, Paula Paulo, Andreia Brandão, Stephen Watya, Alexander Lubwama, Jeannette T Bensen, Elizabeth TH Fontham, James Mohler, Jack A Taylor, Manolis Kogevinas, Javier Llorca, Gemma Castaño-Vinyals, Lisa Cannon-Albright, Craig C Teerlink, Chad D Huff, Sara S Strom, Luc Multigner, Pascal Blanchet, Laurent Brureau, Radka Kaneva, Chavdar Slavov, Vanio Mitev, Robin J Leach, Brandi Weaver, Hermann Brenner, Katarina Cuk, Bernd Holleczek, Kai-Uwe Saum, Eric A Klein, Ann W Hsing, Rick A Kittles, Adam B Murphy, Christopher J Logothetis, Jeri Kim, Susan L Neuhausen, Linda Steele, Yuan Chun Ding, William B Isaacs, Barbara Nemesure, Anselm Jm Hennis, John Carpten, Hardev Pandha, Agnieszka Michael, Kim De Ruyck, Gert De Meerleer, Piet Ost, Jianfeng Xu, Azad Razack, Jasmine Lim, Soo-Hwang Teo, Lisa F Newcomb, Daniel W Lin, Jay H Fowke, Christine Neslund-Dudas, Benjamin A Rybicki, Marija Gamulin, Davor Lessel, Tomislav Kulis, Nawaid Usmani, Sandeep Singhal, Matthew Parliament, Frank Claessens, Steven Joniau, Thomas Van den Broeck, Manuela Gago-Dominguez, Jose Esteban Castelao, Maria Elena Martinez, Samantha Larkin, Paul A Townsend, Claire Aukim-Hastie, William S Bush, Melinda C Aldrich, Dana C Crawford, Shiv Srivastava, Jennifer C Cullen, Gyorgy Petrovics, Graham Casey, Monique J Roobol, Guido Jenster, Ron HN van Schaik, Jennifer J Hu, Maureen Sanderson, Rohit Varma, Roberta McKean-Cowdin, Mina Torres, Nicholas Mancuso, Sonja I Berndt, Stephen K Van Den Eeden, Douglas F Easton, Stephen J Chanock, Michael B Cook, Fredrik Wiklund, Hidewaki Nakagawa, John S Witte, Rosalind A Eeles, Zsofia Kote-Jarai, Christopher A Haiman
Dec 01, 2020
Prostate cancer is a highly heritable disease with large disparities in incidence rates across ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 cases...
A genome-wide association search for type 2 diabetes genes in African Americans.
Nicholette D Palmer, Caitrin W McDonough, Pamela J Hicks, Bong H Roh, Maria R Wing, S Sandy An, Jessica M Hester, Jessica N Cooke, Meredith A Bostrom, Megan E Rudock, Matthew E Talbert, Joshua P Lewis, DIAGRAM Consortium, MAGIC Investigators, Assiamira Ferrara, Lingyi Lu, Julie T Ziegler, Michele M Sale, Jasmin Divers, Daniel Shriner, Adebowale Adeyemo, Charles N Rotimi, Maggie CY Ng, Carl D Langefeld, Barry I Freedman, Donald W Bowden, Benjamin F Voight, Laura J Scott, Valgerdur Steinthorsdottir, Andrew P Morris, Christian Dina, Ryan P Welch, Eleftheria Zeggini, Cornelia Huth, Yurii S Aulchenko, Gudmar Thorleifsson, Laura J McCulloch, Teresa Ferreira, Harald Grallert, Najaf Amin, Guanming Wu, Cristen J Willer, Soumya Raychaudhuri, Steve A McCarroll, Claudia Langenberg, Oliver M Hofmann, Josée Dupuis, Lu Qi, Ayellet V Segrè, Mandy van Hoek, Pau Navarro, Kristin Ardlie, Beverley Balkau, Rafn Benediktsson, Amanda J Bennett, Roza Blagieva, Eric Boerwinkle, Lori L Bonnycastle, Kristina Bengtsson Boström, Bert Bravenboer, Suzannah Bumpstead, Noël P Burtt, Guillaume Charpentier, Peter S Chines, Marilyn Cornelis, David J Couper, Gabe Crawford, Alex SF Doney, Katherine S Elliott, Amanda L Elliott, Michael R Erdos, Caroline S Fox, Christopher S Franklin, Martha Ganser, Christian Gieger, Niels Grarup, Todd Green, Simon Griffin, Christopher J Groves, Candace Guiducci, Samy Hadjadj, Neelam Hassanali, Christian Herder, Bo Isomaa, Anne U Jackson, Paul RV Johnson, Torben Jørgensen, Wen HL Kao, Norman Klopp, Augustine Kong, Peter Kraft, Johanna Kuusisto, Torsten Lauritzen, Man Li, Aloysius Lieverse, Cecilia M Lindgren, Valeriya Lyssenko, Michel Marre, Thomas Meitinger, Kristian Midthjell, Mario A Morken, Narisu Narisu, Peter Nilsson, Katharine R Owen, Felicity Payne, John RB Perry, Ann-Kristin Petersen, Carl Platou, Christine Proença, Inga Prokopenko, Wolfgang Rathmann, N William Rayner, Neil R Robertson, Ghislain Rocheleau, Michael Roden, Michael J Sampson, Richa Saxena, Beverley M Shields, Peter Shrader, Gunnar Sigurdsson, Thomas Sparsø, Klaus Strassburger, Heather M Stringham, Qi Sun, Amy J Swift, Barbara Thorand, Jean Tichet, Tiinamaija Tuomi, Rob M van Dam, Timon W van Haeften, Thijs van Herpt, Jana V van Vliet-Ostaptchouk, G Bragi Walters, Michael N Weedon, Cisca Wijmenga, Jacqueline Witteman, Richard N Bergman, Stephane Cauchi, Francis S Collins, Anna L Gloyn, Ulf Gyllensten, Torben Hansen, Winston A Hide, Graham A Hitman, Albert Hofman, David J Hunter, Kristian Hveem, Markku Laakso, Karen L Mohlke, Andrew D Morris, Colin NA Palmer, Peter P Pramstaller, Igor Rudan, Eric Sijbrands, Lincoln D Stein, Jaakko Tuomilehto, Andre Uitterlinden, Mark Walker, Nicholas J Wareham, Richard M Watanabe, Goncalo R Abecasis, Bernhard O Boehm, Harry Campbell, Mark J Daly, Andrew T Hattersley, Frank B Hu, James B Meigs, James S Pankow, Oluf Pedersen, H-Erich Wichmann, Inês Barroso, Jose C Florez, Timothy M Frayling, Leif Groop, Rob Sladek, Unnur Thorsteinsdottir, James F Wilson, Thomas Illig, Philippe Froguel, Cornelia M van Duijn, Kari Stefansson, David Altshuler, Michael Boehnke, Mark I McCarthy, Nicole Soranzo, Eleanor Wheeler, Nicole L Glazer, Nabila Bouatia-Naji, Reedik Mägi, Joshua Randall, Toby Johnson, Paul Elliott, Denis Rybin, Peter Henneman, Abbas Dehghan, Jouke Jan Hottenga, Kijoung Song, Anuj Goel, Josephine M Egan, Taina Lajunen, Alex Doney, Stavroula Kanoni, Christine Cavalcanti-Proença, Meena Kumari, Nicholas J Timpson, Carina Zabena, Erik Ingelsson, Ping An, Jeffrey O'Connell, Jian'an Luan, Amanda Elliott, Steven A McCarroll, Rosa Maria Roccasecca, François Pattou, Praveen Sethupathy, Yavuz Ariyurek, Philip Barter, John P Beilby, Yoav Ben-Shlomo, Sven Bergmann, Murielle Bochud, Amélie Bonnefond, Knut Borch-Johnsen, Yvonne Böttcher, Eric Brunner, Suzannah J Bumpstead, Yii-Der Ida Chen, Peter Chines, Robert Clarke, Lachlan JM Coin, Matthew N Cooper, Laura Crisponi, Ian NM Day, Eco JC de Geus, Jerome Delplanque, Annette C Fedson, Antje Fischer-Rosinsky, Nita G Forouhi, Rune Frants, Maria Grazia Franzosi, Pilar Galan, Mark O Goodarzi, Jürgen Graessler, Scott Grundy, Rhian Gwilliam, Göran Hallmans, Naomi Hammond, Xijing Han, Anna-Liisa Hartikainen, Caroline Hayward, Simon C Heath, Serge Hercberg, Andrew A Hicks, David R Hillman, Aroon D Hingorani, Jennie Hui, Joe Hung, Antti Jula, Marika Kaakinen, Jaakko Kaprio, Y Antero Kesaniemi, Mika Kivimaki, Beatrice Knight, Seppo Koskinen, Peter Kovacs, Kirsten Ohm Kyvik, G Mark Lathrop, Debbie A Lawlor, Olivier Le Bacquer, Cécile Lecoeur, Yun Li, Robert Mahley, Massimo Mangino, Alisa K Manning, María Teresa Martínez-Larrad, Jarred B McAteer, Ruth McPherson, Christa Meisinger, David Melzer, David Meyre, Braxton D Mitchell, Sutapa Mukherjee, Silvia Naitza, Matthew J Neville, Ben A Oostra, Marco Orrù, Ruth Pakyz, Giuseppe Paolisso, Cristian Pattaro, Daniel Pearson, John F Peden, Nancy L Pedersen, Markus Perola, Andreas FH Pfeiffer, Irene Pichler, Ozren Polasek, Danielle Posthuma, Simon C Potter, Anneli Pouta, Michael A Province, Bruce M Psaty, Nigel W Rayner, Kenneth Rice, Samuli Ripatti, Fernando Rivadeneira, Olov Rolandsson, Annelli Sandbæk, Manjinder Sandhu, Serena Sanna, Avan Aihie Sayer, Paul Scheet, Udo Seedorf, Stephen J Sharp, Beverley Shields, Eric JG Sijbrands, Angela Silveira, Laila Simpson, Andrew Singleton, Nicholas L Smith, Ulla Sovio, Amy Swift, Holly Syddall, Ann-Christine Syvänen, Toshiko Tanaka, Anke Tönjes, André G Uitterlinden, Ko Willems van Dijk, Dhiraj Varma, Sophie Visvikis-Siest, Veronique Vitart, Nicole Vogelzangs, Gérard Waeber, Peter J Wagner, Andrew Walley, Kim L Ward, Hugh Watkins, Sarah H Wild, Gonneke Willemsen, Jaqueline CM Witteman, John WG Yarnell, Diana Zelenika, Björn Zethelius, Guangju Zhai, Jing Hua Zhao, M Carola Zillikens, Ingrid B Borecki, Ruth JF Loos, Pierre Meneton, Patrik KE Magnusson, David M Nathan, Gordon H Williams, Kaisa Silander, Veikko Salomaa, George Davey Smith, Stefan R Bornstein, Peter Schwarz, Joachim Spranger, Fredrik Karpe, Alan R Shuldiner, Cyrus Cooper, George V Dedoussis, Manuel Serrano-Ríos, Lars Lind, Lyle J Palmer, Paul W Franks, Shah Ebrahim, Michael Marmot, WH Linda Kao, Peter Paul Pramstaller, Alan F Wright, Michael Stumvoll, Anders Hamsten, Thomas A Buchanan, Timo T Valle, Jerome I Rotter, David S Siscovick, Brenda WJH Penninx, Dorret I Boomsma, Panos Deloukas, Timothy D Spector, Luigi Ferrucci, Antonio Cao, Angelo Scuteri, David Schlessinger, Manuela Uda, Aimo Ruokonen, Marjo-Riitta Jarvelin, Dawn M Waterworth, Peter Vollenweider, Leena Peltonen, Vincent Mooser, Robert Sladek
Jun 11, 2018
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to identify genes associated...
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