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The progression of disorder-specific brain pattern expression in schizophrenia over 9 years.
Johannes Lieslehto, Erika Jääskeläinen, Vesa Kiviniemi, Marianne Haapea, Peter B Jones, Graham K Murray, Juha Veijola, Udo Dannlowski, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Anne Ruef, Matti Isohanni, Peter Falkai, Jouko Miettunen, Dominic B Dwyer, Nikolaos Koutsouleris
Jul 21, 2021
Age plays a crucial role in the performance of schizophrenia vs. controls (SZ-HC) neuroimaging-based machine learning (ML) models as the accuracy of identifying first-episode psychosis from controls is poor compared to chronic...
The progression of disorder-specific brain pattern expression in schizophrenia over 9 years
Johannes Lieslehto, Erika Jääskeläinen, Vesa Kiviniemi, Marianne Haapea, Peter B. Jones, Graham K. Murray, Juha Veijola, Udo Dannlowski, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Anne Ruef, Matti Isohanni, Peter Falkai, Jouko Miettunen, Dominic B. Dwyer, Nikolaos Koutsouleris
Jun 14, 2021
Abstract: Age plays a crucial role in the performance of schizophrenia vs. controls (SZ-HC) neuroimaging-based machine learning (ML) models as the accuracy of identifying first-episode psychosis from controls is poor compared to...
The progression of disorder-specific brain pattern expression in schizophrenia over 9 years.
Johannes Lieslehto, Erika Jääskeläinen, Vesa Kiviniemi, Marianne Haapea, Peter B Jones, Graham K Murray, Juha Veijola, Udo Dannlowski, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Anne Ruef, Matti Isohanni, Peter Falkai, Jouko Miettunen, Dominic B Dwyer, Nikolaos Koutsouleris
Jul 28, 2021
Age plays a crucial role in the performance of schizophrenia vs. controls (SZ-HC) neuroimaging-based machine learning (ML) models as the accuracy of identifying first-episode psychosis from controls is poor compared to chronic...
Published by: NPJ schizophrenia
Imperfect integration
Decision-making on the basis of multiple information sources is common. However, to what extent such decisions differ from those with a single source remains unclear. We combined cognitive modelling and neural-mass modelling to...
Experimental Investigation of Ion Formation for Auto-Ignition Combustion in a High-Temperature and High-Pressure Combustion Vessel
One of the main challenges in internal combustion engine design is the simultaneous reduction of all engine pollutants like carbon monoxide (CO), total unburned hydrocarbons (THC), nitrogen oxides (NOx), and soot....
Understanding Cryptocurrency
This exploratory applied study examines the nature and dimensions of cryptocurrency, namely bitcoin, a peer-to-peer network for facilitating digital barter. As the most widely used cryptocurrency, bitcoin has carved itself a...
Published by: IGI Global Scientific Publishing
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Dominik Trzupek, Melanie Dunstan, Antony J. Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B. Rainbow, Dominik Aschenbrenner, Joanne L. Jones, Holm H. Uhlig, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira
Jun 24, 2021
Abstract: Background: Traditionally, the transcriptomic and proteomic characterisation of CD4+ T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing...
Experimental Investigation of Ion Formation for Auto-Ignition Combustion in a High-Temperature and High-Pressure Combustion Vessel
One of the main challenges in internal combustion engine design is the simultaneous reduction of all engine pollutants like carbon monoxide (CO), total unburned hydrocarbons (THC), nitrogen oxides (NOx), and soot....
The feet in human--computer interaction
Foot-operated computer interfaces have been studied since the inception of human--computer interaction. Thanks to the miniaturisation and decreasing cost of sensing technology, there is an increasing interest exploring this...
Helicase Subunit Cdc45 Targets the Checkpoint Kinase Rad53 to Both Replication Initiation and Elongation Complexes after Fork Stalling.
Across eukaryotes, disruption of DNA replication causes an S phase checkpoint response, which regulates multiple processes, including inhibition of replication initiation and fork stabilization. How these events are coordinated...
Cdc45 DNA Damage DNA Replication Rad53 budding yeast checkpoint replisome Cell Cycle Proteins Checkpoint Kinase 2 Congenital Microtia DNA Damage DNA Repair DNA Replication DNA Fungal DNA-Binding Proteins Growth Disorders Humans Micrognathism Mutation Nuclear Proteins Patella Phosphorylation Protein Binding S Phase Cell Cycle Checkpoints Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis.
Dominik Trzupek, Melanie Dunstan, Antony J Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B Rainbow, Dominik Aschenbrenner, Joanne L Jones, Holm H Uhlig, Linda S Wicker, John A Todd, Ricardo C Ferreira
Sep 09, 2020
BACKGROUND: Traditionally, the transcriptomic and proteomic characterisation of CD4+ T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing (scRNA-seq) and...
AbSeq C-C chemokine receptor type 9 (CCR9) CD4+ T cells CD80 CD86 Immunophenotyping multi-omics regulatory T cells (tregs) Single-cell RNA sequencing (scRNA-seq) Adolescent Adult B7-1 Antigen B7-2 Antigen Female Forkhead Transcription Factors Humans Male Proteome RNA RNA-seq Single-Cell Analysis T-Lymphocytes Regulatory Transcriptome
Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation.
There is evidence to suggest that increasing the level of saturation (that is, the number of sp3-hybridized carbon atoms) of small molecules can increase their likelihood of success in the drug discovery pipeline1. Owing to...
Two decades of tuberculosis surveillance reveal disease spread, high levels of exposure and mortality and marked variation in disease progression in wild meerkats.
Nadine Müller-Klein, Alice Risely, Dominik W Schmid, Marta Manser, Tim Clutton-Brock, Simone Sommer
Sep 02, 2022
3D-CFD RANS Methodology to Predict Engine-Out Emissions with Gasoline-Like Fuel and Methanol for a DISI Engine
Stefania Esposito, Ali Chaychizadeh, Dominik Golc, Raik Hesse, Joachim Beeckmann, Heinz Pitsch
Sep 16, 2022
Renewable fuels, such as bio- and e-fuels, are of great interest for the defossilization of the transport sector. Among these fuels, methanol represents a promising candidate for emission reduction and efficiency increase due...
/dk/atira/pure/subjectarea/asjc/2200/2203 name=Automotive Engineering /dk/atira/pure/subjectarea/asjc/2200/2213 name=Safety, Risk, Reliability and Quality /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Anomalous sequence of quantum hall liquids revealing a tunable Lifshitz transition in bilayer graphene
Anastasia Varlet, Dominik Bischoff, Pauline Simonet, Kenji Watanabe, Takashi Taniguchi, Thomas Ihn, Klaus Ensslin, Marcin Mucha-Kruczynski, Vladimir I. Fal’ko
Sep 12, 2014
Bilayer graphene is a unique system where both the Fermi energy and the low-energy electron dispersion can be tuned. This is brought about by an interplay between trigonal warping and the band gap opened by a transverse electric...
The feet in human--computer interaction
Foot-operated computer interfaces have been studied since the inception of human--computer interaction. Thanks to the miniaturisation and decreasing cost of sensing technology, there is an increasing interest exploring this...
3D-CFD RANS Methodology to Predict Engine-Out Emissions with Gasoline-Like Fuel and Methanol for a DISI Engine
Stefania Esposito, Ali Chaychizadeh, Dominik Golc, Raik Hesse, Joachim Beeckmann, Heinz Pitsch
Sep 16, 2022
Renewable fuels, such as bio- and e-fuels, are of great interest for the defossilization of the transport sector. Among these fuels, methanol represents a promising candidate for emission reduction and efficiency increase due...
/dk/atira/pure/subjectarea/asjc/2200/2203 name=Automotive Engineering /dk/atira/pure/subjectarea/asjc/2200/2213 name=Safety, Risk, Reliability and Quality /dk/atira/pure/subjectarea/asjc/2300/2310 name=Pollution /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Local Structure and Dynamics in Methylammonium, Formamidinium, and Cesium Tin(II) Mixed-Halide Perovskites from 119Sn Solid-State NMR.
Dominik J Kubicki, Daniel Prochowicz, Elodie Salager, Aydar Rakhmatullin, Clare P Grey, Lyndon Emsley, Samuel D Stranks
Apr 06, 2020
Organic-inorganic tin(II) halide perovskites have emerged as promising alternatives to lead halide perovskites in optoelectronic applications. While they suffer from considerably poorer performance and stability in comparison to...
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Dominik Trzupek, Melanie Dunstan, Antony J. Cutler, Mercede Lee, Leila Godfrey, Lorna Jarvis, Daniel B. Rainbow, Dominik Aschenbrenner, Joanne L. Jones, Holm H. Uhlig, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira
Jun 25, 2020
Abstract: Background: Traditionally, the transcriptomic and proteomic characterisation of CD4+ T cells at the single-cell level has been performed by two largely exclusive types of technologies: single-cell RNA sequencing...
Inflammatory Proteins HMGA2 and PRTN3 as Drivers of Vulvar Squamous Cell Carcinoma Progression.
Agnieszka Fatalska, Natalia Rusetska, Elwira Bakuła-Zalewska, Artur Kowalik, Sebastian Zięba, Agnieszka Wroblewska, Kamil Zalewski, Krzysztof Goryca, Dominik Domański, Magdalena Kowalewska
Mar 08, 2021
Current knowledge on the biology of squamous cell vulvar carcinoma (VSCC) is limited. We aimed to identify protein markers of VSCC tumors that would permit to stratify patients by progression risk. Early-stage tumors from...
Tuning the Mechanical Response of Metal−Organic Frameworks by Defect Engineering
Stefano Dissegna, Pia Vervoorts, Claire Hobday, Tina Duren, Dominik Daisenberger, Andrew Smith, Roland A Fischer, Gregor Kieslich
Sep 19, 2018
The incorporation of defects into crystalline materials provides an important tool to fine-tune properties throughout various fields of materials science. We performed high-pressure powder X-ray diffraction experiments...
Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue.
Joachim Pfister, Dominik Summer, Christine Rangger, Milos Petrik, Elisabeth von Guggenberg, Paolo Minazzi, Giovanni B Giovenzana, Luigi Aloj, Clemens Decristoforo
Dec 18, 2018
BACKGROUND: 6-[Bis(carboxymethyl)amino]-1,4-bis(carboxymethyl)-6-methyl-1,4-diazepane (AAZTA ) is a promising chelator with potential advantages over 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) for...
Anomalous sequence of quantum hall liquids revealing a tunable Lifshitz transition in bilayer graphene
Anastasia Varlet, Dominik Bischoff, Pauline Simonet, Kenji Watanabe, Takashi Taniguchi, Thomas Ihn, Klaus Ensslin, Marcin Mucha-Kruczynski, Vladimir I. Fal’ko
Sep 12, 2014
Bilayer graphene is a unique system where both the Fermi energy and the low-energy electron dispersion can be tuned. This is brought about by an interplay between trigonal warping and the band gap opened by a transverse electric...
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