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International Law and Democracy Revisited
Jan Klabbers, Doreen Lustig, Andre Nollkaemper, Sarah Nouwen, Michal Saliternik, Joseph HH Weiler
May 20, 2021
The European Journal of International Law was founded in 1989, coinciding with the fall of the Berlin Wall and the attendant excitement encapsulated by that well-known optimistic/hubristic End of History phraseology. Many...
Identification of a novel cell type in peripheral lymphoid organs of mice: III. Functional properties in vivo
[No abstract available]
Published by: Rockefeller University
Program for the Stage Production An Evening of One Acts
ProTheatre Club
Jan 01, 0001
This four-page program details the ProTheatre of Ursinus College's production of "An Evening of One Acts", held November 14 and November 15, 1975 in the Bearpit theater. It includes information regarding the three productions...
Ubu Roi Doreen Not Enough Rope ProTheatre theater program Ursinus College Theatre and Performance Studies Theatre History
Published by: Ursinus College
Clinical Translation of Neutrophil Imaging and Its Role in Cancer.
Neutrophils are the first line of defense against pathogens and abnormal cells. They regulate many biological processes such as infections and inflammation. Increasing evidence demonstrated a role for neutrophils in cancer...
In Vivo Cell Tracking Using PET
Cell therapy is a rapidly evolving field involving a wide spectrum of therapeutic cells for personalised medicine in cancer. In vivo imaging and tracking of cells can provide useful information for improving the accuracy...
MexAB-OprM Efflux Pump Interaction with the Peptidoglycan of Escherichia coli and Pseudomonas aeruginosa
Miao Ma, Margaux Lustig, Michèle Salem, Dominique Mengin-Lecreulx, Gilles Phan, Isabelle Broutin
May 21, 2021
One of the major families of membrane proteins found in prokaryote genome corresponds to the transporters. Among them, the resistance-nodulation-cell division (RND) transporters are highly studied, as being responsible for one...
In Vivo Cell Tracking Using PET
Cell therapy is a rapidly evolving field involving a wide spectrum of therapeutic cells for personalised medicine in cancer. In vivo imaging and tracking of cells can provide useful information for improving the accuracy...
Immunotherapy Cell therapy PET/CT reporter genes Cell Tracking Pet/mri Immuno-PET direct cell labelling
Published by: Cancers
MexAB-OprM Efflux Pump Interaction with the Peptidoglycan of Escherichia coli and Pseudomonas aeruginosa.
Miao Ma, Margaux Lustig, Michèle Salem, Dominique Mengin-Lecreulx, Gilles Phan, Isabelle Broutin
Jul 07, 2021
One of the major families of membrane proteins found in prokaryote genome corresponds to the transporters. Among them, the resistance-nodulation-cell division (RND) transporters are highly studied, as being responsible for one...
Pseudomonas efflux pump assembly membrane Peptidoglycan resistance Bacterial Outer Membrane Proteins Cell Wall Drug Resistance Bacterial Escherichia coli Membrane Transport Proteins Models Molecular Peptidoglycan Protein Interaction Domains and Motifs Protein Stability Protein Structure Quaternary Pseudomonas aeruginosa
In Vivo Cell Tracking Using PET
Cell therapy is a rapidly evolving field involving a wide spectrum of therapeutic cells for personalised medicine in cancer. In vivo imaging and tracking of cells can provide useful information for improving the accuracy...
Clinical Translation of Neutrophil Imaging and Its Role in Cancer.
Neutrophils are the first line of defense against pathogens and abnormal cells. They regulate many biological processes such as infections and inflammation. Increasing evidence demonstrated a role for neutrophils in cancer...
A Multiscale Model for Solute Diffusion in Hydrogels.
Eneko Axpe, Doreen Chan, Giovanni S Offeddu, Yin Chang, David Merida, Hector Lopez Hernandez, Eric A Appel
Apr 20, 2020
The number of biomedical applications of hydrogels is increasing rapidly on account of their unique physical, structural, and mechanical properties. The utility of hydrogels as drug delivery systems or tissue engineering...
The Ursinus Weekly, April 12, 1973
John T. Fidler, David Ochocki, Richard Whaley, Nancy Shislar, Judith James, John Kraus, Larry Neustadter, Robert Vietri, Gary Griffith, Ruthann Connell
Jan 01, 0001
Board of Control meets, elects John Fidler editor; New staff chosen for Fall J-Board plans complete; Meat boycott discussed Alpha Phi Omega plans Ecological concern cites collection days IR Club to go to NY Meistersingers...
Ursinus College Collegeville Pennsylvania newspaper student government Judiciary Board meat boycott Alpha Phi Omega Meistersingers International Relations Club Committee for Ecological Concern recycling F. Scott Pierce J.C. Noman Miller Wismer dining hall Poseidon adventure Bob Sing track tennis baseball lacrosse gymnastics cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
David K Finlay, Ella Rosenzweig, Linda V Sinclair, Carmen Feijoo-Carnero, Jens L Hukelmann, Julia Rolf, Andrey A Panteleyev, Klaus Okkenhaug, Doreen A Cantrell
Jun 28, 2018
mTORC1 (mammalian target of rapamycin complex 1) controls transcriptional programs that determine CD8+ cytolytic T cell (CTL) fate. In some cell systems, mTORC1 couples phosphatidylinositol-3 kinase (PI3K) and Akt to the control...
3-Phosphoinositide-Dependent Protein Kinases Animals Aryl Hydrocarbon Receptor Nuclear Translocator CD8-Positive T-Lymphocytes Cell Differentiation Cell Movement Chemokines Gene Expression Regulation Glucose Glycolysis Hypoxia-Inducible Factor 1 Hypoxia-Inducible Factor 1 alpha Subunit Interleukin-2 Mechanistic Target of Rapamycin Complex 1 Mice Mice Inbred C57BL Mice Mutant Strains Mice Transgenic Multiprotein Complexes Phosphatidylinositol 3-Kinases Protein Serine-Threonine Kinases Proteins Proto-Oncogene Proteins c-akt Receptors Antigen T-Cell Receptors Chemokine TOR Serine-Threonine Kinases
Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma
Doreen Lau, Mary A McLean, Andrew N Priest, Andrew B Gill, Francis Scott, Ilse Patterson, Bruno Carmo, Frank Riemer, Joshua D Kaggie, Amy Frary, Doreen Milne, Catherine Booth, Arthur Lewis, Michal Sulikowski, Lee Brown, Jean-Martin Lapointe, Luigi Aloj, Martin J Graves, Kevin M Brindle, Pippa G Corrie, Ferdia A Gallagher
Oct 01, 2021
Background: Immune checkpoint inhibitors are now standard of care treatment for many cancers. Treatment failure in metastatic melanoma is often due to tumor heterogeneity, which is not easily captured by conventional CT or tumor...
Introducing an algal carbon-concentrating mechanism into higher plants
Nicky Atkinson, Doreen Feike, Luke CM Mackinder, Moritz T Meyer, Howard Griffiths, Martin C Jonikas, Alison M Smith, Alistair J McCormick
Feb 01, 2019
Many eukaryotic green algae possess biophysical carbon-concentrating mechanisms (CCMs) that enhance photosynthetic efficiency and thus permit high growth rates at low CO2 concentrations. They are thus an attractive option for...
Arabidopsis thaliana Chlamydomonas reinhardtii bicarbonate transporter Carbon-concentrating mechanism photosynthesis improvement Tobacco Algal Proteins Arabidopsis Carbon Carbon Dioxide Carbonic Anhydrases Chlamydomonas reinhardtii Chloroplasts Gene Expression Regulation Plant Genes Reporter Mutation Photosynthesis Plants Genetically Modified Recombinant Fusion Proteins Tobacco Transgenes
Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model.
Doreen Lau, Fabien Garçon, Anita Chandra, Laura M Lechermann, Luigi Aloj, Edwin R Chilvers, Pippa G Corrie, Klaus Okkenhaug, Ferdia A Gallagher
Jun 12, 2020
adoptive T-cell therapy Immune Checkpoint Inhibitors immunocompetent intravital imaging Melanoma Adoptive Transfer Animals Antigens Neoplasm Cell Line Tumor Cell Movement Combined Modality Therapy Disease Models Animal Fluorescent Antibody Technique Image Processing Computer-Assisted Immune Checkpoint Inhibitors Immunotherapy Adoptive Lymphocyte Activation Melanoma Experimental Mice Molecular Imaging T-Cell Antigen Receptor Specificity T-Lymphocytes
Correlating Radiomic Features of Heterogeneity on CT with Circulating Tumor DNA in Metastatic Melanoma.
Andrew B Gill, Leonardo Rundo, Jonathan CM Wan, Doreen Lau, Jeries P Zawaideh, Ramona Woitek, Fulvio Zaccagna, Lucian Beer, Davina Gale, Evis Sala, Dominique-Laurent Couturier, Pippa G Corrie, Nitzan Rosenfeld, Ferdia A Gallagher
Nov 18, 2020
Clinical imaging methods, such as computed tomography (CT), are used for routine tumor response monitoring. Imaging can also reveal intratumoral, intermetastatic, and interpatient heterogeneity, which can be quantified using...
Super-killer CTLs are generated by single gene deletion of Bach2.
Philippa R Barton, Alexander J Davenport, Jens Hukelmann, Doreen A Cantrell, Jane C Stinchcombe, Arianne C Richard, Gillian M Griffiths
Sep 26, 2022
Bach2 codes for a transcriptional regulator exerting major influences on T cell-mediated immune regulation. Effector CTLs derived from in vitro activation of murine CD8+ T cells showed increased proliferative and cytolytic...
Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model
Doreen Lau, Fabien Garçon, Anita Chandra, Laura M. Lechermann, Luigi Aloj, Edwin R. Chilvers, Pippa G. Corrie, Klaus Okkenhaug, Ferdia A. Gallagher
Aug 05, 2020
Efficient T-cell targeting, infiltration and activation within tumors is crucial for successful adoptive T-cell therapy. Intravital microscopy is a powerful tool for the visualization of T-cell behavior within tumors, as well as...
Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma.
Doreen Lau, Mary A McLean, Andrew N Priest, Andrew B Gill, Francis Scott, Ilse Patterson, Bruno Carmo, Frank Riemer, Joshua D Kaggie, Amy Frary, Doreen Milne, Catherine Booth, Arthur Lewis, Michal Sulikowski, Lee Brown, Jean-Martin Lapointe, Luigi Aloj, Martin J Graves, Kevin M Brindle, Pippa G Corrie, Ferdia A Gallagher
Aug 09, 2021
BACKGROUND: Immune checkpoint inhibitors are now standard of care treatment for many cancers. Treatment failure in metastatic melanoma is often due to tumor heterogeneity, which is not easily captured by conventional CT or tumor...
The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy.
Luigi Aloj, Bala Attili, Doreen Lau, Corradina Caraco, Laura M Lechermann, Iosif A Mendichovszky, Ines Harper, Heok Cheow, Ruth T Casey, Evis Sala, Fiona J Gilbert, Ferdia A Gallagher
Jun 15, 2020
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