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Results: 41
Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A.
Elena V Pavlova, Dorit Lev, Marina Michelson, Keren Yosovich, Hila Gur Michaeli, Nicholas A Bright, Paul T Manna, Veronica Kane Dickson, Karen L Tylee, Heather J Church, J Paul Luzio, Timothy M Cox
Oct 10, 2022
Whose (Greek passage) ? Aaron’s enigmatic response to Moses in Lev 10
Abstract
Aaron’s enigmatic response to Moses’ accusation of cultic malpractice in the disposal of the remains of the ḥaṭṭāt (Lev 10:19) has puzzled...
N MacDonald
Oct 01, 2020
Contextualizing genetic risk score for disease screening and rare variant discovery.
Dan Zhou, Dongmei Yu, Jeremiah M Scharf, Carol A Mathews, Lauren McGrath, Edwin Cook, S Hong Lee, Lea K Davis, Eric R Gamazon
Aug 26, 2021
Studies of the genetic basis of complex traits have demonstrated a substantial role for common, small-effect variant polygenic burden (PB) as well as large-effect variants (LEV, primarily rare). We identify sufficient conditions...
Photosynthetically Controlled Spirulina, but Not Solar Spirulina, Inhibits TNF-α Secretion
Abstract: An array of infections, including the novel coronavirus (SARS-CoV-2), trigger macrophage activation syndrome (MAS) and subsequently hypercytokinemia, commonly referred to as a cytokine storm (CS). It is postulated that...
Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer.
Lipid-transfer proteins (LTPs) were initially discovered as cytosolic factors that facilitate lipid transport between membrane bilayers in vitro. Since then, many LTPs have been isolated from bacteria, plants, yeast, and...
Compounding Transient Airfoil Motions and the Effectiveness of Linear Superposition
This paper investigates, for the first time, the effects of compounding transient airfoil motions and the predictive capability of the linear superposition principle in vortex dominated flows. Significant increases in the...
Unsteady Lift and Moment of a Periodically Plunging Airfoil
To simulate the effects of gusts and maneuvers, lift, moment, and flow measurements are presented for a periodically plunging airfoil at a Reynolds number of 20,000 over a wide range of reduced frequency (k≤1.1), amplitude...
Investigation of mechanisms of high lift for a flat-plate airfoil undergoing small-amplitude plunging oscillations
Two high-lift mechanisms, namely, convected leading-edge vortices and stable deflected jets, have previously been identified for an airfoil undergoing small-amplitude plunging oscillations. In this paper the effect of geometry...
Unsteady Lift and Moment of a Periodically Plunging Airfoil
To simulate the effects of gusts and maneuvers, lift, moment, and flow measurements are presented for a periodically plunging airfoil at a Reynolds number of 20,000 over a wide range of reduced frequency (k≤1.1), amplitude...
Science and islands in Indo-Pacific worlds.
This Introduction offers a conceptualization of the Indo-Pacific, its islands and their place within the history of science. We argue that Indo-Pacific islands present a remarkable combination of social, political and spatial...
Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer
Lipid-transfer proteins (LTPs) were initially discovered as cytosolic factors that facilitate lipid transport between membrane bilayers in vitro. Since then, many LTPs have been isolated from bacteria, plants, yeast, and...
Lift enhancement through flexibility of plunging wings at low Reynolds numbers
In this paper the combined effect of two mechanisms for lift enhancement at low Reynolds numbers are considered, wing oscillations and wing flexibility. The force, deformation and flow fields of rigid and flexible low aspect...
Compounding Transient Airfoil Motions and the Effectiveness of Linear Superposition
This paper investigates, for the first time, the effects of compounding transient airfoil motions and the predictive capability of the linear superposition principle in vortex dominated flows. Significant increases in the...
Lift enhancement through flexibility of plunging wings at low Reynolds numbers
In this paper the combined effect of two mechanisms for lift enhancement at low Reynolds numbers are considered, wing oscillations and wing flexibility. The force, deformation and flow fields of rigid and flexible low aspect...
Investigation of mechanisms of high lift for a flat-plate airfoil undergoing small-amplitude plunging oscillations
Two high-lift mechanisms, namely, convected leading-edge vortices and stable deflected jets, have previously been identified for an airfoil undergoing small-amplitude plunging oscillations. In this paper the effect of geometry...
A Multi-resolution Gaussian process model for the analysis of large spatial data sets
A multi-resolution model is developed to predict two-dimensional spatial fields based on irregularly spaced observations. The radial basis functions at each level of resolution are constructed using a Wendland compactly...
A Multi-resolution Gaussian process model for the analysis of large spatial data sets
A multi-resolution model is developed to predict two-dimensional spatial fields based on irregularly spaced observations. The radial basis functions at each level of resolution are constructed using a Wendland compactly...
Photosynthetically Controlled Spirulina, but Not Solar Spirulina, Inhibits TNF-α Secretion
An array of infections, including the novel coronavirus (SARS-CoV-2), trigger macrophage activation syndrome (MAS) and subsequently hypercytokinemia, commonly referred to as a cytokine storm (CS). It is postulated that CS is...
A fate-map for cranial sensory ganglia in the sea lamprey.
Melinda S Modrell, Dorit Hockman, Benjamin Uy, David Buckley, Tatjana Sauka-Spengler, Marianne E Bronner, Clare VH Baker
Dec 18, 2015
The impact of war on the environment and health
Francesca Racioppi, Harry Rutter, Dorit Nitzan, Anja Borojevic, Zhanat Carr, Tanya Jean Grygaski, Dorota Jarosińska, Sinaia Netanyahu, Oliver Schmoll, Karien Stuetzle, Amber Van Den Akker, Hans Henri P Kluge
Sep 17, 2022
/dk/atira/pure/sustainabledevelopmentgoals/no_poverty name=SDG 1 - No Poverty /dk/atira/pure/sustainabledevelopmentgoals/zero_hunger name=SDG 2 - Zero Hunger /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being /dk/atira/pure/sustainabledevelopmentgoals/gender_equality name=SDG 5 - Gender Equality /dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitation name=SDG 6 - Clean Water and Sanitation /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/industry_innovation_and_infrastructure name=SDG 9 - Industry, Innovation, and Infrastructure /dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalities name=SDG 10 - Reduced Inequalities /dk/atira/pure/sustainabledevelopmentgoals/sustainable_cities_and_communities name=SDG 11 - Sustainable Cities and Communities /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water /dk/atira/pure/sustainabledevelopmentgoals/life_on_land name=SDG 15 - Life on Land /dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions name=SDG 16 - Peace, Justice and Strong Institutions
Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity.
Lindsay E Wu, Dorit Samocha-Bonet, P Tess Whitworth, Daniel J Fazakerley, Nigel Turner, Trevor J Biden, David E James, James Cantley
Aug 28, 2020
A critical feature of obesity is enhanced insulin secretion from pancreatic β-cells, enabling the majority of individuals to maintain glycaemic control despite adiposity and insulin resistance. Surprisingly, the factors...
adipocyte adipokine BMI body mass index Beta-cell ELISA enzyme-linked immunosorbant assay FABP4 GSIS glucose-stimulated insulin secretion IBMX 3-Isobutyl-1-methylxanthine Insulin Secretion NEFA non-esterified fatty acid obesity SILAC stable-isotope labelling by amino acids in cell culture T2D type 2 diabetes cAMP cyclic-AMP
Situating pedagogy
Harry Daniels
Jan 01, 2010
In this paper, I discuss a development within the cultural historical tradition in social science that makes a contribution to our understanding of pedagogy and thus to research in education. This departure involves the...
Situating pedagogy
Harry Daniels
Jan 01, 2010
In this paper, I discuss a development within the cultural historical tradition in social science that makes a contribution to our understanding of pedagogy and thus to research in education. This departure involves the...
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