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Results: 31
Polymorphism of the azobenzene dye compound methyl yellow
Dyanne L. Cruickshank, Christopher H. Hendon, Matthew J R Verbeek, Aron Walsh, Chick C. Wilson
May 21, 2016
The crystal structure and polymorphism of the well-known aminoazobenzene, N,N-dimethyl-4-aminoazobenzene (DAB) are studied; a second polymorph of DAB reported and the relationship between the two polymorphs studied using...
Polymorphism of the azobenzene dye compound methyl yellow
Dyanne L. Cruickshank, Christopher H. Hendon, Matthew J R Verbeek, Aron Walsh, Chick C. Wilson
May 21, 2016
The crystal structure and polymorphism of the well-known aminoazobenzene, N,N-dimethyl-4-aminoazobenzene (DAB) are studied; a second polymorph of DAB reported and the relationship between the two polymorphs studied using...
Crystallisation and physicochemical property characterisation of conformationally-locked co-crystals of fenamic acid derivatives
Kate Wittering, Lauren Agnew, Anneke R Klapwijk, Karen Robertson, Alexander Cousen, Dyanne Cruickshank, Chick Wilson
May 21, 2015
Polymorphism in drug compounds can cause significant problems for industrial-scale production and so a method for restricting the conformational freedom of the target compound whilst retaining desired chemical properties is...
Crystallisation and physicochemical property characterisation of conformationally-locked co-crystals of fenamic acid derivatives
Kate Wittering, Lauren Agnew, Anneke R Klapwijk, Karen Robertson, Alexander Cousen, Dyanne Cruickshank, Chick Wilson
May 21, 2015
Polymorphism in drug compounds can cause significant problems for industrial-scale production and so a method for restricting the conformational freedom of the target compound whilst retaining desired chemical properties is...
NICE guidance on the use of carmustine wafers in high grade gliomas
Transfer-function-free technique for the noninvasive determination of the human arterial pressure waveform.
Alessandro Giudici, Carlo Palombo, Carmela Morizzo, Michaela Kozakova, J Kennedy Cruickshank, Ian B Wilkinson, Ashraf W Khir
Sep 23, 2021
Online Adaptive Learning
Adaptive Learning (AL), a new web-based online learning environment, requires self-regulated learners who act autonomously. However, to date, there appears to be no existing model to conceptualize different aspects of SRL skills...
Published by: IGI Global Scientific Publishing
Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1)
Thomas M MacDonald, Bryan Williams, Mark Caulfield, J Kennedy Cruickshank, Gordon McInnes, Peter Sever, David J Webb, Isla S Mackenzie, Jackie Salsbury, Steve Morant, Ian Ford, Morris J Brown
Jun 25, 2015
CLINICAL PHARMACOLOGY Adolescent Adult Aged Antihypertensive Agents blood pressure Blood Pressure Monitoring Ambulatory Double-Blind Method Drug Therapy Combination Essential Hypertension Female Hemodynamics Humans Hydrochlorothiazide Hypertension Losartan Male Medication Adherence Middle Aged Prospective Studies Young Adult
A multi-centered trial investigating gestational treatment with ursodeoxycholic acid compared to metformin to reduce effects of diabetes mellitus (GUARD)
Holly Lovell, Alice Mitchell, Caroline Ovadia, Noelia Pitrelli, Annette Briley, Claire Singh, Hanns-Ulrich Marschall, Kennedy Cruickshank, Helen Murphy, Paul Seed, Catherine Williamson
Jul 19, 2022
BACKGROUND: Each year in the UK, approximately 35,000 women develop gestational diabetes mellitus (GDM). The condition increases the risk of obstetric and neonatal complications for mother and child, including preeclampsia...
A multi-centered trial investigating gestational treatment with ursodeoxycholic acid compared to metformin to reduce effects of diabetes mellitus (GUARD)
Holly Lovell, Alice Mitchell, Caroline Ovadia, Noelia Pitrelli, Annette Briley, Claire Singh, Hanns-Ulrich Marschall, Kennedy Cruickshank, Helen Murphy, Paul Seed, Catherine Williamson
Aug 19, 2022
BACKGROUND: Each year in the UK, approximately 35,000 women develop gestational diabetes mellitus (GDM). The condition increases the risk of obstetric and neonatal complications for mother and child, including preeclampsia...
Gestational diabetes mellitus Metformin Randomized clinical trial Treatment Ursodeoxycholic Acid Blood Glucose Diabetes mellitus Type 2 Diabetes Gestational Female Glucose Humans Infant Newborn Metformin Multicenter Studies as Topic Pregnancy premature birth Randomized Controlled Trials as Topic Ursodeoxycholic Acid
Comparison of single and combination diuretics on glucose tolerance (PATHWAY-3)
Morris J Brown, Bryan Williams, Thomas M MacDonald, Mark Caulfield, J Kennedy Cruickshank, Gordon McInnes, Peter Sever, David J Webb, Jackie Salsbury, Steve Morant, Ian Ford
Jun 25, 2015
CLINICAL PHARMACOLOGY Adolescent Adult Aged Amiloride Blood Glucose blood pressure Clinical Protocols Diuretics Double-Blind Method Drug Therapy Combination Essential Hypertension Female Glucose Intolerance Glucose Tolerance Test Humans Hydrochlorothiazide Hypertension Logistic Models Male Middle Aged Single-Blind Method Young Adult
Prevention And Treatment of Hypertension With Algorithm-based therapy (PATHWAY) number 2
Bryan Williams, Thomas M MacDonald, Mark Caulfield, J Kennedy Cruickshank, Gordon McInnes, Peter Sever, David J Webb, Jackie Salsbury, Steve Morant, Ian Ford, Morris J Brown
Sep 02, 2015
Drug Treatment Resistant hypertension Adolescent Adult Aged Algorithms Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Antihypertensive Agents Calcium Channel Blockers Clinical Protocols Cross-Over Studies Diuretics Double-Blind Method Drug Therapy Combination Humans Hypertension Male Middle Aged Spironolactone Young Adult
Morris J Brown, Bryan Williams, Steve V Morant, David J Webb, Mark J Caulfield, J Kennedy Cruickshank, Ian Ford, Gordon McInnes, Peter Sever, Jackie Salsbury, Isla S Mackenzie, Sandosh Padmanabhan, Thomas M MacDonald, British Hypertension Society's Prevention and Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group
Sep 24, 2015
Improving the Quality of Care in Care Homes Using the Quality Improvement Collaborative Approach
Reena Devi, Graham Martin, Jay Banerjee, Louise Butler, Tim Pattison, Lesley Cruickshank, Caroline Maries-Tillott, Tracie Wilson, Sarah Damery, Julienne Meyer, Antonius Poot, Peter Chamberlain, Debbie Harvey, Clarissa Giebel, Kathryn Hinsliff-Smith, Neil Chadborn, Adam Lee Gordon
Oct 20, 2020
The Breakthrough Series Quality Improvement Collaborative (QIC) initiative is a well-developed and widely used approach, but most of what we know about it has come from healthcare settings. In this article, those leading QICs to...
Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2)
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.
Matthew D Young, Thomas J Mitchell, Felipe A Vieira Braga, Maxine GB Tran, Benjamin J Stewart, John R Ferdinand, Grace Collord, Rachel A Botting, Dorin-Mirel Popescu, Kevin W Loudon, Roser Vento-Tormo, Emily Stephenson, Alex Cagan, Sarah J Farndon, Martin Del Castillo Velasco-Herrera, Charlotte Guzzo, Nathan Richoz, Lira Mamanova, Tevita Aho, James N Armitage, Antony CP Riddick, Imran Mushtaq, Stephen Farrell, Dyanne Rampling, James Nicholson, Andrew Filby, Johanna Burge, Steven Lisgo, Patrick H Maxwell, Susan Lindsay, Anne Y Warren, Grant D Stewart, Neil Sebire, Nicholas Coleman, Muzlifah Haniffa, Sarah A Teichmann, Menna Clatworthy, Sam Behjati
Nov 13, 2018
Messenger RNA encodes cellular function and phenotype. In the context of human cancer, it defines the identities of malignant cells and the diversity of tumor tissue. We studied 72,501 single-cell transcriptomes of human renal...
Single cell derived mRNA signals across human kidney tumors.
Matthew D Young, Thomas J Mitchell, Lars Custers, Thanasis Margaritis, Francisco Morales-Rodriguez, Kwasi Kwakwa, Eleonora Khabirova, Gerda Kildisiute, Thomas R W Oliver, Ronald R de Krijger, Marry M van den Heuvel-Eibrink, Federico Comitani, Alice Piapi, Eva Bugallo-Blanco, Christine Thevanesan, Christina Burke, Elena Prigmore, Kirsty Ambridge, Kenny Roberts, Felipe A Vieira Braga, Tim H H Coorens, Ignacio Del Valle, Anna Wilbrey-Clark, Lira Mamanova, Grant D Stewart, Vincent J Gnanapragasam, Dyanne Rampling, Neil Sebire, Nicholas Coleman, Liz Hook, Anne Warren, Muzlifah Haniffa, Marcel Kool, Stefan M Pfister, John C Achermann, Xiaoling He, Roger A Barker, Adam Shlien, Omer A Bayraktar, Sarah A Teichmann, Frank C Holstege, Kerstin B Meyer, Jarno Drost, Karin Straathof, Sam Behjati
Jul 28, 2021
Kidney Fetus Humans Kidney Neoplasms RNA Messenger Signal Transduction Gene Expression Regulation Developmental Algorithms Models Genetic Adult Child Single-Cell Analysis Transcriptome RNA-seq
Published by: Nature Communications
Validation of non-invasive central blood pressure devices
James E Sharman, Alberto P Avolio, Johannes Baulmann, Athanase Benetos, Jacques Blacher, C Leigh Blizzard, Pierre Boutouyrie, Chen-Huan Chen, Phil Chowienczyk, John R Cockcroft, J Kennedy Cruickshank, Isabel Ferreira, Lorenzo Ghiadoni, Alun Hughes, Piotr Jankowski, Stephane Laurent, Barry J McDonnell, Carmel McEniery, Sandrine C Millasseau, Theodoros G Papaioannou, Gianfranco Parati, Jeong Bae Park, Athanase D Protogerou, Mary J Roman, Giuseppe Schillaci, Patrick Segers, George S Stergiou, Hirofumi Tomiyama, Raymond R Townsend, Luc M Van Bortel, Jiguang Wang, Siegfried Wassertheurer, Thomas Weber, Ian B Wilkinson, Charalambos Vlachopoulos
Nov 21, 2018
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