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Predicting the Occurrence of Variants in RAG1 and RAG2.
While widespread genome sequencing ushers in a new era of preventive medicine, the tools for predictive genomics are still lacking. Time and resource limitations mean that human diseases remain uncharacterized because of an...
Predicting the Occurrence of Variants in RAG1 and RAG2
Abstract: While widespread genome sequencing ushers in a new era of preventive medicine, the tools for predictive genomics are still lacking. Time and resource limitations mean that human diseases remain uncharacterized because...
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies
Metlay, J.P., Witmer-Pack, M.D., Agger, R., Crowley, M.T., Lawless, D., and Steinman, R.M. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J. Exp. Med. 171...
Developing Written Argumentation Skills With an Educational Simulation Game (ESG)
In this chapter, the authors present the case of GlobalEd, a virtual educational simulation game (ESG) that focuses on the development of student written argumentation and socio-scientific literacy skills over the course of...
Enhancing Student Affect From Multi-Classroom Simulation Games via Teacher Professional Development
Educational simulations often require players to maintain a high degree of engagement for play in the simulation to continue. Student motivation and engagement is tied to affective factors, such as interest and self-efficacy. As...
Hybrid and Virtual Educational Simulation Games (vESGs) for the Remote Learning Era
Virtual educational simulation games (vESGs) promote unique combinations of learning interactions and affordances to create environments with which students can engage to effectively learn about complex phenomena and processes...
The Sage Page Fall 2017
Inside this issue: Welcome by Dr. Lyon Meet the Officers Letter from WUHA! President Photo Story: Awesome Honors Events Alumni Story 2017 Seniors How the Honors Program Helped me Earn Five Scholarships Being Honors and Greek...
Published by: Winthrop University
Defining and Designing Responsive Online Professional Development (ROPD)
Teacher professional development programs typically do not meet teachers' ongoing, long-term needs that arise. In this chapter, the authors forward a systematic framework called responsive online professional development (ROPD)...
Modeling Alzheimer's Disease Using CRISPR/CAS9 Gene Editing and Induced Pluripotent Stem Cells Reveals Conserved Cellular Mechanisms
Dylan Kwart
Jan 01, 0001
Alzheimer's disease (AD) is the most common cause of dementia worldwide and a leading cause of death in the United States. Rare cases of autosomal dominant familial AD (fAD) result from genetic mutations in three key genes...
Published by: Rockefeller University
Pleistocene Water Crossings and Adaptive Flexibility Within the Homo Genus
Dylan Gaffney
Apr 29, 2021
Abstract: Pleistocene water crossings, long thought to be an innovation of Homo sapiens, may extend beyond our species to encompass Middle and Early Pleistocene Homo. However, it remains unclear how water crossings differed...
Synthesis and Analysis of Small Fluorogenic Probes for Chlorite Detection
Dylan Ford
Jan 01, 0001
Chlorite is a common water contaminant that is most commonly introduced to drinking water sources through wastewater disinfection and textile bleaching. Consumption of elevated levels of chlorite have been shown to produce...
Published by: Ursinus College
The Regulation of Cathepsin L Activity by Estrogen and Bisphenols A & S: Relationship to Systemic Lupus Erythematosus
Dylan T Cuva
Jan 01, 0001
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that is linked to increased levels of estrogen. Bisphenol A (BPA) is an environmental estrogen that may also play a role in SLE. BPA is used in the production of...
Published by: Ursinus College
The understanding, acceptability, and relevance of personalised multidimensional physical activity feedback among urban adults
Background
Wearable technologies are being used to provide personalised feedback across multiple physical activity dimensions in countries such as the UK, but their feasibility has not been tested in South Asia, where...
Identification of the lz4 Suppressor of pam-1 and its Role in Polarity Establishment in Single-cell C. elegans Embryos
Dylan Stephens
Jan 01, 0001
In the nematode Caenorhabditis elegans, cell polarity in the single-cell embryo is indicative of anterior-posterior (AP) axis formation, which is essential for future functional potential. AP axis polarization is initiated by...
Published by: Ursinus College
Pleistocene Water Crossings and Adaptive Flexibility Within the Homo Genus
Dylan Gaffney
Sep 14, 2021
Abstract: Pleistocene water crossings, long thought to be an innovation of Homo sapiens, may extend beyond our species to encompass Middle and Early Pleistocene Homo. However, it remains unclear how water crossings differed...
Identification of the lz4 Suppressor of pam-1 and its Role in Polarity Establishment in One-Cell C. elegans Embryos
Dylan Stephens
Jan 01, 0001
In the nematode Caenorhabdatis elegans, anterior-posterior (AP) axis formation in the single-cell embryo is indicative of cell polarity, which is essential for the achievement of future functional potential. AP axis polarization...
Published by: Ursinus College
A Cellular and Molecular Characterization of the Microglial Cell Population in Ambystoma mexicanum
Dylan T Ammons
Jan 01, 0001
The central nervous system (CNS), which consists of the spinal cord and brain, is complex and needs to be better understood. To gain insight, a single cellular population, the microglial cells, are described in the healthy and...
Published by: Ursinus College

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