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HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome.
Cell Line Tumor Chromatin Chromatin Assembly and Disassembly Cyclin-Dependent Kinase 9 Epigenesis Genetic Female Gene Expression Regulation Neoplastic Gene Expression Regulation Viral Genome Viral Human papillomavirus 16 Humans Oncogene Proteins Viral Papillomavirus E7 Proteins Repressor Proteins Uterine Cervical Neoplasms Virus Integration
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
Duuamene Nyimanu, Fiona A Chapman, Peter J Gallacher, Rhoda E Kuc, Thomas L Williams, David E Newby, Janet J Maguire, Anthony P Davenport, Neeraj Dhaun
Jul 20, 2022
AIMS: Chronic kidney disease (CKD) is common and cardiovascular disease (CVD) is its commonest complication. The apelin system is a potential therapeutic target for CVD but data relating to apelin in CKD are limited. We examined...
The Use of Chest Voice in African-American Religious Singing
Robert T. Townsend
Nov 19, 2013
Chest resonance is used during singing events in most African-American churches. Actually, it is the way of singing for most folk singing. I remember the presentation by a Russian professor demonstrating the folk singing of his...
Published by: Faculty of Education
The Use of Chest Voice in African-American Religious Singing
Robert T. Townsend
Nov 19, 2013
Chest resonance is used during singing events in most African-American churches. Actually, it is the way of singing for most folk singing. I remember the presentation by a Russian professor demonstrating the folk singing of his...
Published by: Faculty of Education
The Relationship between the Firing Rate of a Single Neuron and the Level of Activity in a Population of Neurons : Experimental Evidence for Resonant Enhancement in the Population Response
Bruce Knight
Jan 01, 0001
A quantitative comparison is made between experiment and the theoretically predicted dynamics of a neuron population. The experiment confirms the theoretical prediction that under appropriate conditions an enlarged resonant...
Published by: The Rockefeller University Press
Canonical Field Theory -- A Prototype Example
Bruce Knight
Jan 01, 0001
The equations of a field may be put into a standard "Lagrangian" form from which several conservation laws follow directly. As an illustrative example, a string free to vibrate in two directions is investigated; this example...
Published by: American Association of Physics Teachers
Dynamics of Encoding in Neuron Populations: Some General Mathematical Features
Bruce Knight
Jan 01, 0001
The use of a population dynamics approach promises efficient simulation of large assemblages of neurons. Depending on the issues addressed and the degree of realism incorporated in the simulated neurons, a wide range of...
common structure frequency response Stability interacting subpopulations orientation hypercolumn Life Sciences
Published by: MIT Press
Reactors of Uniform Power, Fuel Loading, and Flux
Bruce Knight
Jan 01, 0001
flat-flux nuclear reactor Tungsten nuclear reactor experimental results Tungsten nuclear rocket reactor Molybdenum nuclear rocket reactor Dumbo nuclear reactor Los Alamos nuclear reactor Life Sciences
Published by: American Nuclear Society
Visual Myths
G. Knight
Jan 01, 2023
Is visual communication primarily contingent upon physical elements to be seen with the eye, or does visuality also extend into the imagination? Despite the progress of modernity since the Enlightenment, a different form of...
Published by: IGI Global Scientific Publishing
How do the prevalence and relative risk of non-suicidal self-injury and suicidal thoughts vary across the population distribution of common mental distress (the p factor)? Observational analyses replicated in two independent UK cohorts of young people.
Ela Polek, Sharon AS Neufeld, Paul Wilkinson, Ian Goodyer, Michelle St Clair, Gita Prabhu, Ray Dolan, Edward T Bullmore, Peter Fonagy, Jan Stochl, Peter B Jones
Apr 03, 2020
child & adolescent psychiatry EPIDEMIOLOGY Public Health suicide & self-harm Adolescent Cohort Studies Female Health Surveys Humans Logistic Models Male Patient Dropouts prevalence psychological distress Reproducibility of Results risk Self-Injurious Behavior Suicidal Ideation United Kingdom Young Adult Suicide Prevention
Spectral attenuation limits of silica hollow core negative curvature fiber
In this paper we discuss the limits of attenuation of silica hollow core negative curvature fibers in the wavelength range from 800 nm up to 4.5 μm. Both numerical and experimental results are presented and show good agreement....
Doctors have an ethical obligation to ask patients about food insecurity
Inadequate diet is the leading risk factor for morbidity and mortality worldwide. However, approaches to identifying inadequate diets in clinical practice remain inconsistent, and dietary interventions (on both individual and...
Spectral attenuation limits of silica hollow core negative curvature fiber
In this paper we discuss the limits of attenuation of silica hollow core negative curvature fibers in the wavelength range from 800 nm up to 4.5 μm. Both numerical and experimental results are presented and show good agreement....
Discussion as part of "Should we sample more frequently?
Discussion as part of Nason, G. P., Powell, B., Elliott, D. and Smith, P. A. (2017), Should we sample a time series more frequently?: decision support via multirate spectrum estimation. J. R. Stat. Soc. A, 180: 353–407....
Effect of core boundary curvature on the confinement losses of hollow antiresonant fibers
We use numerical simulations to investigate how the curvature of the fiber core boundary influences the attenuation of hollow antiresonant fibers. We show the importance of a "negative" curvature core boundary in reducing...
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