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Results: 10656
Interview with Edward "Ed" Harris, Brenda Dow, and Sylvester King - OH 296
In May of 2013 Mr. Edward Harris sat down and discussed his brother, Herman K. Harris, who was a part of the freedom riders. Mr. Harris also discusses his military service and his tour of duty in Vietnam. This interview was...
Sharecropper African American education Southern Family Heath Springs South Carolina Segregation Freedom Riders KKK Vietnam PTSD Oral History
Published by: Winthrop University
Interview with Edward Bynum - OH 322
This collection includes an interview of Edward Bynum (1933-2012) concerning his work with the Dr. James R. Clark Memorial Sickle Cell Anemia Foundation. Bynum discusses his education, his service in the Korean War on a hospital...
Sickle cell anemia and trait Thalassemia James R. Clark Memorial Sickle Cell Foundation CDC (Centers for Disease Control and Prevention) DHEC (Department of Health and Environmental Control) Hematology Dr. James R. Clark Oral History
Published by: Winthrop University
Digital Game-Based Learning in an Introductory Accounting Course
This study aimed to develop and evaluate a digital instructional game application for learning the basic concepts of the accounting principles in an introductory accounting course. The game was designed using the Unity engine...
Published by: IGI Global Scientific Publishing
de Sitter Microstates from $T\bar T+Λ_2$ and the Hawking-Page
Transition
Evan Coleman, Edward A Mazenc, Vasudev Shyam, Eva Silverstein, Ronak Soni, Gonzalo Torroba, Sungyeon Yang
Jul 28, 2022
We obtain microstates accounting for the Gibbons-Hawking entropy in $dS_3$,
along with a subleading logarithmic correction, from the solvable $T\bar
T+\Lambda_2$ deformation of a seed CFT with sparse light spectrum....
Published by: Springer Berlin Heidelberg
Cultural Differences in Digital Game Experiences
The literature proposes that East Asians have a holistic view focusing on both salient objects and their backgrounds, whereas Westerners maintain an analytic view paying attention to focal objects and their attributes. Moreover...
Published by: IGI Global Scientific Publishing
Coordinating pricing and inventory decisions in a multi-level supply chain
This paper concerns coordination of enterprise decisions such as suppliers and components selection, pricing and inventory in a multi-level supply chain composed of multiple suppliers, a single manufacturer and multiple...
Coordinating pricing and inventory decisions in a multi-level supply chain
This paper concerns coordination of enterprise decisions such as suppliers and components selection, pricing and inventory in a multi-level supply chain composed of multiple suppliers, a single manufacturer and multiple...
B-hadron production in NNLO QCD
We calculate, for the first time, the NNLO QCD corrections to identified
heavy hadron production at hadron colliders. The calculation is based on a
flexible numeric framework which allows the calculation of any distribution of
a...
Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells.
Meryem Aloulou, Edward J Carr, Mylène Gador, Alexandre Bignon, Roland S Liblau, Nicolas Fazilleau, Michelle A Linterman
Jun 24, 2019
T follicular regulatory (Tfr) cells are a subset of Foxp3(+) regulatory T (Treg) cells that form in response to immunization or infection, which localize to the germinal centre where they control the magnitude of the response....
Restriction endonuclease TseI cleaves A:A and T
Long Ma, Kai Chen, David J Clarke, Christopher P Nortcliffe, Geoffrey G Wilson, J Michael Edwardson, A Jennifer Morton, Anita C Jones, David TF Dryden
Feb 13, 2020
The type II restriction endonuclease TseI recognizes the DNA target sequence 5'-G^CWGC-3' (where W = A or T) and cleaves after the first G to produce fragments with three-base 5'-overhangs. We have determined that it is a...
Board Game Pedagogy
Annotated game rules for a film history board game as well as all cards designed for the project.
film History Education Board Games pedagogy communication Educational Methods game design Higher Education Other Film and Media Studies Other History of Art, Architecture, and Archaeology
Published by: Ursinus College
Interview with Booker T. Brown - OH 689
This interview was conducted by Dr. George Garrison with Booker T. Brown with a focus on the History of Emmett Scott High School. Emmett Scott was the segregated high school for African-Americans, which was named after Emmett...
Published by: Winthrop University
The innovation game
Purpose: This paper seeks to present a teaching tool (the Innovation Game) which aims to demonstrate the challenges of developing an effective innovation strategy in the context of new product development. The goal of the game...
Game or Simulation Implementation
Brian Grey
Jan 01, 0001
Student will design/will have previously designed a video game or simulation, including any necessary modeling and mechanics. They will then implement the game using their preferred language (although Unity or Python will be...
Published by: Harrisburg University of Science and Technology
Functional proteomic atlas of HIV infection in primary human CD4+ T cells.
Adi Naamati, James C Williamson, Edward JD Greenwood, Sara Marelli, Paul J Lehner, Nicholas J Matheson
Mar 28, 2019
Viruses manipulate host cells to enhance their replication, and the identification of cellular factors targeted by viruses has led to key insights into both viral pathogenesis and cell biology. In this study, we develop an HIV...
HIV human immunology infectious disease Inflammation magnetic cell selection microbiology primary human CD4+ T cell Proteomics Virus CD4-Positive T-Lymphocytes Cell Separation Cluster Analysis DNA-Binding Proteins Fragile X Mental Retardation Protein Gene Expression Regulation Green Fluorescent Proteins HIV Infections HIV-1 Humans Hydrogen-Ion Concentration Lentivirus Lymphocyte Activation Magnetics Methyltransferases Protein Binding Protein Tyrosine Phosphatase Non-Receptor Type 22 Proteome Proteomics Streptavidin Virus Replication vif Gene Products Human Immunodeficiency Virus
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4 + T Cells
Daisy H. Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T. Hawkins, Len R. Stephens, Simon T. Barry, Klaus Okkenhaug
Mar 22, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells.
Daisy H Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T Hawkins, Len R Stephens, Simon T Barry, Klaus Okkenhaug
Feb 03, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
CD4-Positive T-Lymphocytes Animals Mice Inbred C57BL Mice Multiprotein Complexes Receptors Antigen T-Cell Interleukin-2 Lymphocyte Activation Specific Pathogen-Free Organisms Signal Transduction Cell Differentiation Gene Knockout Techniques Class I Phosphatidylinositol 3-Kinases CRISPR-Cas Systems Gene Editing
Antigen discrimination by T cells relies on size-constrained microvillar contact.
Edward Jenkins, Markus Körbel, Caitlin O'Brien-Ball, James McColl, Kevin Y Chen, Mateusz Kotowski, Jane Humphrey, Anna H Lippert, Heather Brouwer, Ana Mafalda Santos, Steven F Lee, Simon J Davis, David Klenerman
Apr 17, 2023
T cells use finger-like protrusions called 'microvilli' to interrogate their targets, but why they do so is unknown. To form contacts, T cells must overcome the highly charged, barrier-like layer of large molecules forming a...
T-Lymphocytes microvilli Receptors Antigen T-Cell Antigens Lymphocyte Activation Signal Transduction
Published by: Nature Communications
Extracellular Lactate
James T Grist, Lorna B Jarvis, Zoya Georgieva, Sara Thompson, Harpreet Kaur Sandhu, Keith Burling, Ashley Clarke, Sarah Jackson, Mark Wills, Ferdia A Gallagher, Joanne L Jones
Feb 23, 2018
Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic...
T Lymphocytes in Histiocytic Sarcomas of Flat-Coated Retriever Dogs.
Flat-Coated Retriever dogs are predisposed to the development of histiocytic sarcoma (HS), a poorly differentiated, highly malignant neoplasm. The authors have previously documented a significant lymphocytic infiltrate in such...
INFIDELS IN ENGLISH LEGAL THOUGHT
English common law reports are dense with ideas. Yet they remain mostly untapped by intellectual historians. This article reveals how intellectual history can engage with law and jurisprudence by following the notion...
EDWARD CAVANAGH
Sep 08, 2018
The innovation game
Purpose: This paper seeks to present a teaching tool (the Innovation Game) which aims to demonstrate the challenges of developing an effective innovation strategy in the context of new product development. The goal of the game...
Blame Game Theory
Research on organizational misconduct has examined how audiences generate discourses to make sense of behaviour that may transgress the line between right and wrong. However, when organizations are accused of misconduct, the...
Cross-discipline evidence principles for sustainability policy.
Edward T Game, Heather Tallis, Lydia Olander, Steven M Alexander, Jonah Busch, Nancy Cartwright, Elizabeth L Kalies, Yuta J Masuda, Anne-Christine Mupepele, Jiangxiao Qiu, Andrew Rooney, Erin Sills, William J Sutherland
Nov 22, 2018
Evidence-based approaches to sustainability challenges must draw on knowledge from the environment, development and health communities. To be practicable, this requires an approach to evidence that is broader and less...
Game-Based Learning for Supply Chain Management
Ghada Deghedi
Jan 01, 2023
Game-based learning has proven to be an effective teaching method in a variety of fields, including supply chain management (SCM). This paper discusses the use of simulation-based business games for training and education in SCM...
Published by: IGI Global Scientific Publishing
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