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Opportunities and Limitations of Mobile Neuroimaging Technologies in Educational Neuroscience.
Protecting Neurons From Damage Using an Antioxidant Derived From Green Tea
Elana Roadcloud
Jan 01, 0001
This research explores the protective effect on neurons of the antioxidant, catechin, following exposure to external stresses, such as thermal stress and oxidative stress in Caenorhabditis elegans. There are different ways to...
Catechin antioxidants green tea neurodegeneration C. elegans Biology Life Sciences Medical Neurobiology Neuroscience and Neurobiology
Published by: Ursinus College
Community Service and Celebration Highlight MLK Day at Winthrop
Winthrop University
Jan 01, 0001
The Inspiration of Life celebration will kick off 5 p.m. in Tillman Hall with performances by Skin Deep, the Vision of Zion dance team, Association of Ebonites Gospel Choir and Vision of Prayze. Greet students participating in...
Published by: Winthrop University
AI-Assisted CT as a Clinical and Research Tool for COVID-19.
Zion Tsz Ho Tse, Sierra Hovet, Hongliang Ren, Tristan Barrett, Sheng Xu, Baris Turkbey, Bradford J Wood
Sep 08, 2021
There is compelling support for widening the role of computed tomography (CT) for COVID-19 in clinical and research scenarios. Reverse transcription polymerase chain reaction (RT-PCR) testing, the gold standard for COVID-19...
Published by: Frontiers in artificial intelligence
The Grizzly, September 19, 2019
Kevin Leon, Samuel Chiche, Rosalia Murphy, Kim Corona, Colleen Murphy, Jenni Berrios, Daniel Walker, Elana Goldman, Gabriela Howell, Lauren Viola
Jan 01, 0001
Two Decades of Ursinus Fringe Festival Professor Walvoord Wins First-Year Advising Award Men's Golf Competes at Spartan Invitational Shammah Bermudez Will Depart from Ursinus Res Life Launches "It's On Me" Campaign Wismer...
Ursinus College Collegeville Pennsylvania newspaper fringe festival Ryan Walvoord golf Shammah Bermudez disability services Residence Life Wismer on Wheels Football field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Visualization of sympathetic neural innervation in human white adipose tissue.
Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M Keogh, I Sadaf Farooqi
Jan 05, 2023
AI-Assisted CT as a Clinical and Research Tool for COVID-19.
Zion Tsz Ho Tse, Sierra Hovet, Hongliang Ren, Tristan Barrett, Sheng Xu, Baris Turkbey, Bradford J Wood
Oct 13, 2021
There is compelling support for widening the role of computed tomography (CT) for COVID-19 in clinical and research scenarios. Reverse transcription polymerase chain reaction (RT-PCR) testing, the gold standard for COVID-19...
Visualization of sympathetic neural innervation in human white adipose tissue.
Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M Keogh, I Sadaf Farooqi
Apr 19, 2022
Olfactory sniffing signals consciousness in unresponsive patients with brain injuries.
Anat Arzi, Liron Rozenkrantz, Lior Gorodisky, Danit Rozenkrantz, Yael Holtzman, Aharon Ravia, Tristan A Bekinschtein, Tatyana Galperin, Ben-Zion Krimchansky, Gal Cohen, Anna Oksamitni, Elena Aidinoff, Yaron Sacher, Noam Sobel
May 06, 2020
After severe brain injury, it can be difficult to determine the state of consciousness of a patient, to determine whether the patient is unresponsive or perhaps minimally conscious1, and to predict whether they will recover....
Visualization of sympathetic neural innervation in human white adipose tissue
Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M. Keogh, I. Sadaf Farooqi
Oct 24, 2022
Methods and techniques obesity Human Adipose Tissue Sympathetic Innervation Whole Tissue Immunolabelling Three-dimensional Microscopy
Published by: The Royal Society
Visualization of sympathetic neural innervation in human white adipose tissue.
Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M Keogh, Ismaa Farooqi
Mar 17, 2022
Divergent effects of central melanocortin signalling on fat and sucrose preference in humans.
Agatha A van der Klaauw, Julia M Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M Trowse, Naresh Subramanian, Stephen O'Rahilly, Paul C Fletcher, I Sadaf Farooqi
Oct 03, 2016
Neural correlates of fat preference in frontotemporal dementia
Rebekah M Ahmed, Nga Yan Tse, Yu Chen, Elana Henning, John R Hodges, Matthew C Kiernan, Muireann Irish, I Sadaf Farooqi, Olivier Piguet
May 11, 2021
Dopamine modulates the neural representation of subjective value of food in hungry subjects.
Nenad Medic, Hisham Ziauddeen, Martin D Vestergaard, Elana Henning, Wolfram Schultz, I Sadaf Farooqi, Paul C Fletcher
Aug 14, 2014
Assessment of Eating Behavior Disturbance and Associated Neural Networks in Frontotemporal Dementia.
Rebekah M Ahmed, Muireann Irish, Elana Henning, Nadene Dermody, Lauren Bartley, Matthew C Kiernan, Olivier Piguet, Sadaf Farooqi, John R Hodges
Sep 27, 2016
Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with delayed gastric emptying.
Eleonora Seelig, Elana Henning, Julia M Keogh, Daniel Gillett, Evelyn Shin, John Buscombe, Agatha A van der Klaauw, I Sadaf Farooqi
Oct 25, 2021
OBJECTIVE: People who are severely obese due to melanocortin-4 receptor (MC4R) deficiency experience hyperphagia and impaired fullness after a meal (satiety). Meal-induced satiety is influenced by hormones, such as peptide-YY...
A rare human variant that disrupts GPR10 signalling causes weight gain in mice.
Fleur Talbot, Claire H Feetham, Jacek Mokrosiński, Katherine Lawler, Julia M Keogh, Elana Henning, Edson Mendes de Oliveira, Vikram Ayinampudi, Sadia Saeed, Amélie Bonnefond, Mohammed Arslan, Giles SH Yeo, Philippe Froguel, David A Bechtold, Antony Adamson, Neil Humphreys, Inês Barroso, Simon M Luckman, I Sadaf Farooqi
Mar 15, 2023
Obesity-associated melanocortin-4 receptor mutations are associated with changes in the brain response to food cues.
Agatha A van der Klaauw, Elisabeth AH von dem Hagen, Julia M Keogh, Elana Henning, Stephen O'Rahilly, Andrew D Lawrence, Andrew J Calder, I Sadaf Farooqi
Aug 19, 2014
Leptin-Mediated Changes in the Human Metabolome.
Katherine Lawler, Isabel Huang-Doran, Takuhiro Sonoyama, Tinh-Hai Collet, Julia M Keogh, Elana Henning, Stephen O'Rahilly, Leonardo Bottolo, I Sadaf Farooqi
May 15, 2020
CONTEXT: While severe obesity due to congenital leptin deficiency is rare, studies in patients before and after treatment with leptin can provide unique insights into the role that leptin plays in metabolic and endocrine...
bile acids Leptin Lipids Metabolomics obesity Adolescent Child Child Preschool Chromatography Liquid Energy Intake Energy Metabolism Female Hormone Replacement Therapy Humans Leptin Lipolysis Loss of Function Mutation Male Metabolome Metabolomics obesity Recombinant Proteins Severity of Illness Index Tandem Mass Spectrometry Treatment Outcome
Energy expenditure in frontotemporal dementia
Rebekah M Ahmed, Ramon Landin-Romero, Tinh-Hai Collet, Agatha A van der Klaauw, Emma Devenney, Elana Henning, Matthew C Kiernan, Olivier Piguet, I Sadaf Farooqi, John R Hodges
Oct 26, 2016
Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities
Takuhiro Sonoyama, Lukas K. J. Stadler, Mingyan Zhu, Julia M. Keogh, Elana Henning, Fuki Hisama, Peter Kirwan, Magdalena Jura, Beata K. Blaszczyk, David C. DeWitt, Bas Brouwers, Marko Hyvönen, Inês Barroso, Florian T. Merkle, Suzanne M. Appleyard, Gary A. Wayman, I. Sadaf Farooqi
Jun 04, 2021
Abstract: Brain-derived neurotrophic factor (BDNF) signals through its high affinity receptor Tropomyosin receptor kinase-B (TrkB) to regulate neuronal development, synapse formation and plasticity. In rodents, genetic...
The Sleep/Wake Cycle is Directly Modulated by Changes in Energy Balance.
Tinh-Hai Collet, Agatha A van der Klaauw, Elana Henning, Julia M Keogh, Diane Suddaby, Sekesai V Dachi, Síle Dunbar, Sarah Kelway, Suzanne L Dickson, I Sadaf Farooqi, Sebastian M Schmid
Oct 07, 2016
Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities.
Takuhiro Sonoyama, Lukas KJ Stadler, Mingyan Zhu, Julia M Keogh, Elana Henning, Fuki Hisama, Peter Kirwan, Magdalena Jura, Beata K Blaszczyk, David C DeWitt, Bas Brouwers, Marko Hyvönen, Inês Barroso, Florian T Merkle, Suzanne M Appleyard, Gary A Wayman, I Sadaf Farooqi
Jul 16, 2020
Brain-derived neurotrophic factor (BDNF) signals through its high affinity receptor Tropomyosin receptor kinase-B (TrkB) to regulate neuronal development, synapse formation and plasticity. In rodents, genetic disruption of Bdnf...
Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation.
Bas Brouwers, Edson Mendes de Oliveira, Maria Marti-Solano, Fabiola BF Monteiro, Suli-Anne Laurin, Julia M Keogh, Elana Henning, Rebecca Bounds, Carole A Daly, Shane Houston, Vikram Ayinampudi, Natalia Wasiluk, David Clarke, Bianca Plouffe, Michel Bouvier, M Madan Babu, I Sadaf Farooqi, Jacek Mokrosiński
Apr 14, 2021
The Melanocortin-4 Receptor (MC4R) plays a pivotal role in energy homeostasis. We used human MC4R mutations associated with an increased or decreased risk of obesity to dissect mechanisms that regulate MC4R function. Most...
GPCRs Gα(s) MC4R MSH melanocortin obesity Therapy Weight Loss β-Arrestin Animals Body Weight COS Cells Cell Membrane Chlorocebus aethiops Cyclic AMP Endocytosis Extracellular Signal-Regulated MAP Kinases GTP-Binding Protein alpha Subunits Gs genetic variation HEK293 Cells Humans Models Biological Mutant Proteins Mutation Phosphorylation Protein Multimerization Receptor Melanocortin Type 4 Signal Transduction beta-Arrestins
Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people.
Joost Overduin, Tinh-Hai Collet, Nenad Medic, Elana Henning, Julia M Keogh, Faye Forsyth, Cheryl Stephenson, Marja W Kanning, Rianne MAJ Ruijschop, I Sadaf Farooqi, Agatha A van der Klaauw
Oct 28, 2016
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