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Results: 39
Immune Cell Associations with Cancer Risk.
Luis Palomero, Ivan Galván-Femenía, Rafael de Cid, Roderic Espín, Daniel R Barnes, CIMBA, Eline Blommaert, Miguel Gil-Gil, Catalina Falo, Agostina Stradella, Dan Ouchi, Albert Roso-Llorach, Concepció Violan, María Peña-Chilet, Joaquín Dopazo, Ana Isabel Extremera, Mar García-Valero, Carmen Herranz, Francesca Mateo, Elisabetta Mereu, Jonathan Beesley, Georgia Chenevix-Trench, Cecilia Roux, Tak Mak, Joan Brunet, Razq Hakem, Chiara Gorrini, Antonis C Antoniou, Conxi Lázaro, Miquel Angel Pujana
Aug 19, 2020
Proper immune system function hinders cancer development, but little is known about whether genetic variants linked to cancer risk alter immune cells. Here, we report 57 cancer risk loci associated with differences in immune...
Sustainable Protein Transformation in China
In a world defined by climate change and biodiversity loss, declining food security, and malnutrition, it is undeniable that the global food system has reached an inflection point. As such, the need to transform the way we...
Sustainable Protein Transformation in China
In a world defined by climate change and biodiversity loss, declining food security, and malnutrition, it is undeniable that the global food system has reached an inflection point. As such, the need to transform the way we...
At, with and beyond risk
Biomedical research aimed at the development of therapies for chronic and late-onset conditions increasingly concentrates on the early treatment of symptom-less disease. This broad trend is evidenced in prominent shifts in...
Charge Carriers Are Not Affected by the Relatively Slow-Rotating Methylammonium Cations in Lead Halide Perovskite Thin Films.
Valentina M Caselli, Mathias Fischer, Daniele Meggiolaro, Edoardo Mosconi, Filippo De Angelis, Samuel D Stranks, Andreas Baumann, Vladimir Dyakonov, Eline M Hutter, Tom J Savenije
Aug 22, 2019
Recently, several studies have investigated dielectric properties as a possible origin of the exceptional optoelectronic properties of metal halide perovskites (MHPs). In this study we investigated the temperature-dependent...
Perspectives on Communicating Biomarker-Based Assessments of Alzheimer's Disease to Cognitively Healthy Individuals.
Richard Milne, Eline Bunnik, Ana Diaz, Edo Richard, Shirlene Badger, Dianne Gove, Jean Georges, Karine Fauria, Jose-Luis Molinuevo, Katie Wells, Craig Ritchie, Carol Brayne
Mar 02, 2018
In clinical trials which target pathophysiological mechanisms associated with Alzheimer's disease, research participants who are recruited based on biomarker test results should be informed about their increased risk of...
Age-related loss of axonal regeneration is reflected by the level of local translation.
Susan van Erp, Annemiek A van Berkel, Eline M Feenstra, Pabitra K Sahoo, Laura J Wagstaff, Jeffery L Twiss, James W Fawcett, Richard Eva, Charles ffrench-Constant
Feb 18, 2021
Regeneration capacity is reduced as CNS axons mature. Using laser-mediated axotomy, proteomics and puromycin-based tagging of newly-synthesized proteins in a human embryonic stem cell-derived neuron culture system that allows...
Vapour-Deposited Cesium Lead Iodide Perovskites
Eline M Hutter, Rebecca J Sutton, Sanjana Chandrashekar, Mojtaba Abdi-Jalebi, Samuel D Stranks, Henry J Snaith, Tom J Savenije
Nov 01, 2018
Metal halide perovskites such as methylammonium lead iodide (MAPbI3) are highly promising materials for photovoltaics. However, the relationship between the organic nature of the cation and the optoelectronic quality remains...
β-Hydroxybutyrate Oxidation in Exercise Is Impaired by Low-Carbohydrate and High-Fat Availability.
David J Dearlove, David Holdsworth, Tom Kirk, Leanne Hodson, Evelina Charidemou, Eline Kvalheim, Brianna Stubbs, Andrew Beevers, Julian L Griffin, Rhys Evans, Jeremy Robertson, Kieran Clarke, Pete J Cox
Jan 04, 2022
Purpose: In this study, we determined ketone oxidation rates in athletes under metabolic conditions of high and low carbohydrate (CHO) and fat availability. Methods: Six healthy male athletes completed 1 h of bicycle ergometer...
The Impact of Phase Retention on the Structural and Optoelectronic Properties of Metal Halide Perovskites.
Anna Osherov, Eline M Hutter, Krzysztof Galkowski, Roberto Brenes, Duncan K Maude, Robin J Nicholas, Paulina Plochocka, Vladimir Bulović, Tom J Savenije, Samuel D Stranks
Aug 16, 2017
The extent to which the soft structural properties of metal halide perovskites affect their optoelectronic properties is unclear. X-ray diffraction and micro-photoluminescence measurements are used to show that there is a...
Is there evidence for bacterial transfer via the placenta and any role in the colonization of the infant gut? - a systematic review.
Angel Gil, Ricardo Rueda, Susan E Ozanne, Eline M van der Beek, Carolien van Loo-Bouwman, Marieke Schoemaker, Vittoria Marinello, Koen Venema, Catherine Stanton, Bettina Schelkle, Matthieu Flourakis, Christine A Edwards
Sep 28, 2020
With the important role of the gut microbiome in health and disease, it is crucial to understand key factors that establish the microbial community, including gut colonization during infancy. It has been suggested that the first...
Estimating HIV Incidence, Time to Diagnosis, and the Undiagnosed HIV Epidemic Using Routine Surveillance Data.
Ard van Sighem, Fumiyo Nakagawa, Daniela De Angelis, Chantal Quinten, Daniela Bezemer, Eline Op de Coul, Matthias Egger, Frank de Wolf, Christophe Fraser, Andrew Phillips
Aug 16, 2018
BACKGROUND: Estimates of the size of the undiagnosed HIV-infected population are important to understand the HIV epidemic and to plan interventions, including "test-and-treat" strategies. METHODS: We developed a multi-state...
Reduced Barrier for Ion Migration in Mixed-Halide Perovskites.
Lucie McGovern, Gianluca Grimaldi, Moritz H Futscher, Eline M Hutter, Loreta A Muscarella, Moritz C Schmidt, Bruno Ehrler
Feb 02, 2022
Halide alloying in metal halide perovskites is a useful tool for optoelectronic applications requiring a specific bandgap. However, mixed-halide perovskites show ion migration in the perovskite layer, leading to phase...
Postnatal growth in preterm infants and later health outcomes
Ken K Ong, Kathy Kennedy, Eurídice Castañeda-Gutiérrez, Stewart Forsyth, Keith M Godfrey, Berthold Koletzko, Marie E Latulippe, Susan E Ozanne, Ricardo Rueda, Marieke H Schoemaker, Eline M van der Beek, Stef van Buuren, Mary Fewtrell
Aug 09, 2017
Postnatal growth in preterm infants and later health outcomes
Kenneth Ong, Kathy Kennedy, Eurídice Castañeda-Gutiérrez, Stewart Forsyth, Keith M Godfrey, Berthold Koletzko, Marie E Latulippe, Susan Ozanne, Ricardo Rueda, Marieke H Schoemaker, Eline M van der Beek, Stef van Buuren, Mary Fewtrell
Nov 04, 2015
In preterm infants, poor postnatal growth is associated with adverse neurocognitive outcomes; conversely, rapid postnatal growth is supposedly harmful for future development of metabolic diseases. CONCLUSION: In this systematic...
Inference of natural selection from ancient DNA.
Marianne Dehasque, María C Ávila-Arcos, David Díez-Del-Molino, Matteo Fumagalli, Katerina Guschanski, Eline D Lorenzen, Anna-Sapfo Malaspinas, Tomas Marques-Bonet, Michael D Martin, Gemma GR Murray, Alexander ST Papadopulos, Nina Overgaard Therkildsen, Daniel Wegmann, Love Dalén, Andrew D Foote
May 22, 2020
Evolutionary processes, including selection, can be indirectly inferred based on patterns of genomic variation among contemporary populations or species. However, this often requires unrealistic assumptions of ancestral...
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Alessandra Stangherlin, Joseph L Watson, David CS Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D Beale, Edward A Hayter, Alina Guna, Alison J Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M Voorhees, David A Bechtold, Emmanuel Derivery, Rachel S Edgar, Peter Newham, John O'Neill
Nov 24, 2021
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic...
Metabolomics Analytics Workflow for Epidemiological Research
Mary C Playdon, Amit D Joshi, Fred K Tabung, Susan Cheng, Mir Henglin, Andy Kim, Tengda Lin, Eline H van Roekel, Jiaqi Huang, Jan Krumsiek, Ying Wang, Ewy Mathé, Marinella Temprosa, Steven Moore, Bo Chawes, A Heather Eliassen, Andrea Gsur, Marc J Gunter, Sei Harada, Claudia Langenberg, Matej Oresic, Wei Perng, Wei Jie Seow, Oana A Zeleznik
Jul 10, 2019
The Pristine Survey – VI. The first three years of medium-resolution follow-up spectroscopy of Pristine EMP star candidates★
David S Aguado, Kris Youakim, Jonay I González Hernández, Carlos Allende Prieto, Else Starkenburg, Nicolas Martin, Piercarlo Bonifacio, Anke Arentsen, Elisabetta Caffau, Luis Peralta de Arriba, Federico Sestito, Rafael Garcia-Diaz, Nicholas Fantin, Vanessa Hill, Pascale Jablonca, Farbod Jahandar, Collin Kielty, Nicolas Longeard, Romain Lucchesi, Rubén Sánchez-Janssen, Yeisson Osorio, Pedro A Palicio, Eline Tolstoy, Thomas G Wilson, Patrick Côté, Georges Kordopatis, Carmela Lardo, Julio F Navarro, Guillaume F Thomas, Kim Venn
Sep 27, 2019
We present the results of a 3-year long, medium-resolution spectroscopic campaign aimed at identifying very metal-poor stars from candidates selected with the CaHK, metallicity-sensitive Pristine survey. The catalogue consists...
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Oct 18, 2021
Abstract: Between 6–20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation...
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Alessandra Stangherlin, Joseph L Watson, David CS Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D Beale, Edward A Hayter, Alina Guna, Alison J Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M Voorhees, David A Bechtold, Emmanuel Derivery, Rachel S Edgar, Peter Newham, John S O'Neill
Dec 15, 2021
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic...
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Alessandra Stangherlin, Joseph L Watson, David C S Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D Beale, Edward A Hayter, Alina Guna, Alison J Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M Voorhees, David A Bechtold, Emmanuel Derivery, Rachel S Edgar, Peter Newham, John S O'Neill
Nov 22, 2021
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic...
Published by: Nature Communications
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