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Results: 106
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
David K Finlay, Ella Rosenzweig, Linda V Sinclair, Carmen Feijoo-Carnero, Jens L Hukelmann, Julia Rolf, Andrey A Panteleyev, Klaus Okkenhaug, Doreen A Cantrell
Jun 28, 2018
mTORC1 (mammalian target of rapamycin complex 1) controls transcriptional programs that determine CD8+ cytolytic T cell (CTL) fate. In some cell systems, mTORC1 couples phosphatidylinositol-3 kinase (PI3K) and Akt to the control...
3-Phosphoinositide-Dependent Protein Kinases Animals Aryl Hydrocarbon Receptor Nuclear Translocator CD8-Positive T-Lymphocytes Cell Differentiation Cell Movement Chemokines Gene Expression Regulation Glucose Glycolysis Hypoxia-Inducible Factor 1 Hypoxia-Inducible Factor 1 alpha Subunit Interleukin-2 Mechanistic Target of Rapamycin Complex 1 Mice Mice Inbred C57BL Mice Mutant Strains Mice Transgenic Multiprotein Complexes Phosphatidylinositol 3-Kinases Protein Serine-Threonine Kinases Proteins Proto-Oncogene Proteins c-akt Receptors Antigen T-Cell Receptors Chemokine TOR Serine-Threonine Kinases
Discovery and Optimization of a Family of Naturally Encoded Antibiotic Compounds that Evade Antibiotic
Adam Rosenzweig
Jan 01, 0001
Antibacterial resistant infections are an ongoing global health emergency. To combat this,novel potent antibiotics with unique modes of action are required. The classic arsenal of antibiotics used in clinical settings are...
Published by: Rockefeller University
Self-assembled monolayer molecule dynamics are perturbed by surface- and surrounding monolayer-derived geometrical confinement
Ella Matthews
Jan 01, 0001
The surface a thin-film is attached to and the surrounding monolayer causes geometrical confinement of a interrogated molecule; we look at the base case of a SC18H37 in a...
Honduras
Ella Adriana Chirinos
Sep 21, 2017
Dependency theorists focus on the economic history of developing economies and the scarce benefits they have received in comparison to developed economies. Although founded in truth, they fail and neglect to highlight the...
Dependency Theory Neoliberalism Developing Economies Dependency Theory Neoliberalism Foreign Direct Investment
Published by: Memorial University of Newfoundland
Colombia's Fork in the Road? President Santos' Treaty with The Revolutionary Armed Forces of Colombia (FARC)
Ella Adriana Chirinos
Aug 22, 2017
Colombia is considered Latin America’s most stable democracy; meanwhile, it is war-torn by the internal conflict with the guerrilla group, the Revolutionary Armed Forces of Colombia (FARC). The armed conflict with the FARC has...
Published by: Memorial University of Newfoundland
National Identity and Sports in Latin America
Ella Adriana Chirinos
Sep 11, 2018
“La Guerra de Fútbol,” Spanish for The Football War, erupted after a qualifying match in Mexico City between El Salvador and Honduras for the 1970 FIFA World Cup. Despite El Salvador winning the match, the state dissolved...
Published by: Memorial University of Newfoundland
The Tendency to Appraise Stressful Situations as More of a Threat is Associated with Poorer Health and Well-Being
It has been argued that habitually appraising stressful events as more of a threat (i.e., situational demands exceed personal coping resources) may increase one's risk of ill-health (e.g., depression). However, while first...
biopsychosocial model Challenge and threat states Cognitive appraisals immunology Mental Health /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Self-assembled monolayer molecule dynamics are perturbed by surface- and surrounding monolayer-derived geometrical confinement
Ella Matthews
Jan 01, 0001
The surface a thin-film is attached to and the surrounding monolayer causes geometrical confinement of a interrogated molecule; we look at the base case of a SC18H37 in a...
Honduras
Ella Adriana Chirinos
Sep 21, 2017
Dependency theorists focus on the economic history of developing economies and the scarce benefits they have received in comparison to developed economies. Although founded in truth, they fail and neglect to highlight the...
Dependency Theory;Neoliberalism Developing Economies, Dependency Theory, Neoliberalism, Foreign Direct Investment
Published by: Memorial University of Newfoundland
National Identity and Sports in Latin America
Ella Adriana Chirinos
Sep 11, 2018
“La Guerra de Fútbol,” Spanish for The Football War, erupted after a qualifying match in Mexico City between El Salvador and Honduras for the 1970 FIFA World Cup. Despite El Salvador winning the match, the state dissolved...
Published by: Memorial University of Newfoundland
Colombia's Fork in the Road? President Santos' Treaty with The Revolutionary Armed Forces of Colombia (FARC)
Ella Adriana Chirinos
Aug 22, 2017
Colombia is considered Latin America’s most stable democracy; meanwhile, it is war-torn by the internal conflict with the guerrilla group, the Revolutionary Armed Forces of Colombia (FARC). The armed conflict with the FARC has...
Published by: Memorial University of Newfoundland
Mental Imagery: The Cognitive Processing of Concrete and Abstract Words
People process concrete words, such as table, faster than abstract words, such as peace. The dual-coding theory posits that concrete words are stored in a verbal format (left hemisphere) and a pictorial format (right...
aphantasia autistic traits dual-coding theory functional near-infrared spectroscopy Mental imagery Psychology Social and Behavioral Sciences
Published by: Ursinus College
“When in France, do as the French do!”
Ella Adriana Chirinos
Sep 11, 2018
With the rise of the far-right in Europe, previously unpopular right-wing parties emerge from the shadows to rival the dominant parties of their state. One such political party which has benefited from the wave of far-right...
Published by: Memorial University of Newfoundland
“When in France, do as the French do!”
Ella Adriana Chirinos
Sep 11, 2018
With the rise of the far-right in Europe, previously unpopular right-wing parties emerge from the shadows to rival the dominant parties of their state. One such political party which has benefited from the wave of far-right...
Published by: Memorial University of Newfoundland
Growth and optical characterisation of multilayers of InGaN quantum dots
We report on the growth (using metal-organic vapour phase epitaxy) and optical
characterization of single and multiple layers of InGaN quantum dots (QDs), which were formed by
annealing InGaN epilayers at the growth temperature...
Letter from the Editors
Published by: Memorial University of Newfoundland
Letter from the Editors
Published by: Memorial University of Newfoundland
The Tendency to Appraise Stressful Situations as More of a Threat is Associated with Poorer Health and Well-Being
It has been argued that habitually appraising stressful events as more of a threat (i.e., situational demands exceed personal coping resources) may increase one's risk of ill-health (e.g., depression). However, while first...
biopsychosocial model Challenge and threat states Cognitive appraisals immunology Mental Health /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Polymers from Sugars and Cyclic Anhydrides
A d-xylose 3,5-anhydrosugar derivative has been used as an oxetane co-monomer in the ring-opening copolymerization (ROCOP) with cyclic anhydrides, to form a family of seven novel sugar-derived polyesters, with up to 100%...
The Ursinus Weekly, February 15, 1926
Valentine fete in Bomberger scene of merriment Debating teams to see action again this week Dr. Beury's address features Founders' Day exercises Negative debating team loses to Bucknell Rev. McKeehan conducts prayer week...
Ursinus College Collegeville Pennsylvania newspaper Charles E. Buery Hobart D. McKeehan Basketball May Day pageant debate team George Koch cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Polymers from Sugars and Cyclic Anhydrides
A d-xylose 3,5-anhydrosugar derivative has been used as an oxetane co-monomer in the ring-opening copolymerization (ROCOP) with cyclic anhydrides, to form a family of seven novel sugar-derived polyesters, with up to 100%...
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