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Results: 233
Information recovery from low coverage whole-genome bisulfite sequencing.
Emanuele Libertini, Simon C Heath, Rifat A Hamoudi, Marta Gut, Michael J Ziller, Agata Czyz, Victor Ruotti, Hendrik G Stunnenberg, Mattia Frontini, Willem H Ouwehand, Alexander Meissner, Ivo G Gut, Stephan Beck
Sep 08, 2018
The cost of whole-genome bisulfite sequencing (WGBS) remains a bottleneck for many studies and it is therefore imperative to extract as much information as possible from a given dataset. This is particularly important because...
Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.
Goran Lakisic, Alice Lebreton, Renaud Pourpre, Olivia Wendling, Emanuele Libertini, Elizabeth J Radford, Morwenna Le Guillou, Marie-France Champy, Marie Wattenhofer-Donzé, Guillaume Soubigou, Slimane Ait-Si-Ali, Jean Feunteun, Tania Sorg, Jean-Yves Coppée, Anne C Ferguson-Smith, Pascale Cossart, Hélène Bierne
Dec 02, 2020
BAHD1 is a vertebrate protein that promotes heterochromatin formation and gene repression in association with several epigenetic regulators. However, its physiological roles remain unknown. Here, we demonstrate that ablation of...
Elucidating the Cognitive Mechanisms Underpinning Behavioural Activation.
Depression represents a pervasive and devastating psychological difficulty. It affects over 21% of the population at some point in their lives and can have an unimaginable impact on both individuals and society. Behavioural...
Cell-Free Scaffolds as a Monotherapy for Focal Chondral Knee Defects.
Chondral knee defects have a limited ability to be repaired. Current surgical interventions have been unable to regenerate articular cartilage with the mechanical properties of native hyaline cartilage. The use of a...
Mid- and Long-Term Health Risks in Living Kidney Donors.
BACKGROUND:
Long-term health risks for adults who donate kidneys are unclear.
PURPOSE:
To summarize evidence about mid- and long-term health risks associated with living kidney donation in adults.
DATA SOURCES:
PubMed, Embase...
Tendon healing is adversely affected by low-grade inflammation.
BACKGROUND: Tendinopathy is common, presents with pain and activity limitation, and is associated with a high risk of recurrence of the injury. Tendinopathy usually occurs as a results of a disrupted healing response to a...
Single top production in PDF fits
Abstract: We study the impact of recent LHC t-channel single top-quark and top-antiquark measurements at centre-of-mass energies of 7, 8 and 13 TeV on the parton distribution functions (PDFs) of the proton. We consider, namely...
Regularising experimental correlations in LHC data
Abstract We show how an inaccurate determination of experimental uncertainty correlations in high-precision LHC measurements may undermine the reliability of the associated...
Single top production in PDF fits
Abstract: We study the impact of recent LHC t-channel single top-quark and top-antiquark measurements at centre-of-mass energies of 7, 8 and 13 TeV on the parton distribution functions (PDFs) of the proton. We consider, namely...
Regularising experimental correlations in LHC data
We show how an inaccurate determination of experimental uncertainty correlations in high-precision LHC measurements may undermine the reliability of the associated χ2. We formulate the problem rigorously, and devise a...
Published by: Springer Berlin Heidelberg
The role of the immune system in tendon healing
INTRODUCTION: The role of the immune system in tendon healing relies on polymorphonucleocytes, mast cells, macrophages and lymphocytes, the 'immune cells' and their cytokine production. This systematic review reports how the...
Cell-Free Scaffolds as a Monotherapy for Focal Chondral Knee Defects
Chondral knee defects have a limited ability to be repaired. Current surgical interventions have been unable to regenerate articular cartilage with the mechanical properties of native hyaline cartilage. The use of a...
Single top production in PDF fits
Abstract: We study the impact of recent LHC t-channel single top-quark and top-antiquark measurements at centre-of-mass energies of 7, 8 and 13 TeV on the parton distribution functions (PDFs) of the proton. We consider, namely...
Effectiveness and safety of tranexamic acid in total joint arthroplasty.
Total joint arthroplasty is associated with significant blood loss, that could result in the need of blood transfusions. Several techniques are being utilised to limit the volume of blood loss, in order to avoid...
Dynamics of cumulative innovation in complex social systems (DCICSS)
Graham Room, Alastair Spence, Evangelos Evangelou, Paolo Zeppini, Emanuele Pugliese, Lorenzo Napolitano
Jan 01, 0001
Dynamic network analysis Cumulative causation in social processes From Auto-Catalytic Networks to Auto-Catalytic Societies Technology ecosystem of patents data
Published by: University of Bath
Genetically Predicted Type 2 Diabetes Mellitus Liability, Glycated Hemoglobin and Cardiovascular Diseases
Bowen Liu, Amy M Mason, Luanluan Sun, Emanuele Di Angelantonio, Dipender Gill, Stephen Burgess
Oct 21, 2021
average blood glucose Cardiovascular Diseases hemoglobin A1c Mendelian randomization type 2 diabetes mellitus aortic valve stenosis Cardiovascular Diseases Coronary Artery Disease Diabetes mellitus Type 2 Female Genetic Association Studies Genetic Predisposition to Disease genetic variation Glycated Hemoglobin Heart Failure Humans ischemic stroke Male Mendelian Randomization Analysis Middle Aged peripheral vascular diseases stroke
Proof of concept for a smart composite orbital debris detector
Mario Emanuele De Simone, Christos Andreades, Amin Mohamad Hilmi, Michele Meo, Francesco Ciampa
Jul 01, 2019
Space debris particles with dimensions smaller than tens of millimetres are not trackable with existing monitoring systems and have sufficient energy to harm orbiting Earth satellites during impact events. This paper presents...
Management of von Willebrand disease in patients undergoing total hip and knee arthroplasty.
Von Willebrand disease is the commonest bleeding disorder encountered in the medical and surgical field. As a result of the repetitive bleeding into the joints many patients suffer from arthropathy that can cause a...
The strangest proton?
Abstract: We present an improved determination of the strange quark and antiquark parton distribution functions of the proton by means of a global QCD analysis that takes into account a comprehensive set of strangeness-sensitive...
The strangest proton?
Abstract: We present an improved determination of the strange quark and antiquark parton distribution functions of the proton by means of a global QCD analysis that takes into account a comprehensive set of strangeness-sensitive...
Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems.
Emanuele Mauri, Alessandro Sacchetti, Nunzio Vicario, Luca Peruzzotti-Jametti, Filippo Rossi, Stefano Pluchino
May 21, 2018
The use of neural stem cells (NSCs) in cell therapy has become a powerful tool used for the treatment of central nervous system diseases, including traumatic brain and spinal cord injuries. However, a significant drawback is...
Proof of concept for a smart composite orbital debris detector
Mario Emanuele De Simone, Christos Andreades, Amin Mohamad Hilmi, Michele Meo, Francesco Ciampa
Jul 01, 2019
Space debris particles with dimensions smaller than tens of millimetres are not trackable with existing monitoring systems and have sufficient energy to harm orbiting Earth satellites during impact events. This paper presents...
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