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Pattern and Rate of Cognitive Decline in Cerebral Small Vessel Disease
Andrew J Lawrence, Rebecca L Brookes, Eva A Zeestraten, Thomas R Barrick, Robin G Morris, Hugh S Markus
Jul 28, 2015
Longitudinal decline in structural networks predicts dementia in cerebral small vessel disease.
Andrew J Lawrence, Eva A Zeestraten, Philip Benjamin, Christian P Lambert, Robin G Morris, Thomas R Barrick, Hugh S Markus
May 23, 2018
OBJECTIVE: To determine whether longitudinal change in white matter structural network integrity predicts dementia and future cognitive decline in cerebral small vessel disease (SVD). To investigate whether network disruption...
Predicting Dementia in Cerebral Small Vessel Disease Using an Automatic Diffusion Tensor Image Segmentation Technique.
Owen A Williams, Eva A Zeestraten, Philip Benjamin, Christian Lambert, Andrew J Lawrence, Andrew D MacKinnon, Robin G Morris, Hugh S Markus, Thomas R Barrick, Rebecca A Charlton
Oct 03, 2019
Background and Purpose- Cerebral small vessel disease (SVD) is the most common cause of vascular cognitive impairment, with a significant proportion of cases going on to develop dementia. We explore the extent to which diffusion...
Brain cerebral small vessel disease Cerebrum Cognition Cognitive Dysfunction Dementia Diffusion tensor imaging Adult Aged Aged 80 and over cerebral small vessel diseases Cognitive Dysfunction Dementia Diffusion tensor imaging Disease Progression Female Humans Image Interpretation Computer-Assisted Male Middle Aged
Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease.
Philip Benjamin, Sarah Trippier, Andrew J Lawrence, Christian Lambert, Eva Zeestraten, Owen A Williams, Bhavini Patel, Robin G Morris, Thomas R Barrick, Andrew D MacKinnon, Hugh S Markus
May 03, 2018
BACKGROUND AND PURPOSE: Cerebral small-vessel disease is a major cause of cognitive impairment. Perivascular spaces (PvS) occur in small-vessel disease, but their relationship to cognitive impairment remains uncertain. One...
Identifying preclinical vascular dementia in symptomatic small vessel disease using MRI.
Christian Lambert, Eva Zeestraten, Owen Williams, Philip Benjamin, Andrew J Lawrence, Robin G Morris, Andrew D MacKinnon, Thomas R Barrick, Hugh S Markus
Oct 18, 2018
Sporadic cerebral small vessel disease is an important cause of vascular dementia, a syndrome of cognitive impairment together with vascular brain damage. At post-mortem pure vascular dementia is rare, with evidence of...
cerebral small vessel disease Preclinical dementia Structural MRI Vascular dementia voxel-based morphometry Aged Aged 80 and over Brain cerebral small vessel diseases Dementia Vascular Early Diagnosis Female Humans Magnetic Resonance Imaging Male Middle Aged Neuroimaging Neuropsychological Tests white matter
Linking axon transport to regeneration using in vitro laser axotomy.
Spinal cord injury has devastating consequences because adult
central nervous system (CNS) neurons do not regenerate their
axons after injury. Two key reasons for axon regeneration failure
are extrinsic inhibitory factors and a...
Texture Analysis of T1 weighted and fluid attenuated inversion recovery images detects abnormalities which correlate with disease progression in small vessel disease
Background and Purpose
MRI techniques may be useful to assess disease severity in cerebral small vessel disease (SVD), identify those individuals who are most likely to progress to dementia, monitor disease progression and act...
Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury
Investigating the molecular mechanisms governing developmental axon growth has been a useful approach for identifying new strategies for boosting axon regeneration after injury, with the goal of treating debilitating conditions...
The Grizzly, April 21, 2022
Layla Halterman, Chase Portaro, Marie Sykes, Jenna Smith, Erin Corcoran, Cici Chagnon, Steven Weissman, Vaughn DiBattista
Jan 01, 0001
A Look Into Ursinus's "Quest" for an Inclusive Campus Contact Without a Trace! Get to Know Dr. Carol Dole Meet Eva Wright! Opinions: Club Sports Should Have Athletic Trainers Trophy Brophy The Get-Back: Ursinus Softball
Ursinus College Collegeville Pennsylvania newspaper Diversity equity inclusion CIE covid-19 coronavirus Carol Dole Wismer dining hall Eva Wright Mike Brophy softball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Accelerated vascular aging
Carole H Sudre, Stefano Moriconi, Rafael Rehwald, Lorna Smith, Therese Tillin, Josephine Barnes, David Atkinson, Sébastien Ourselin, Nish Chaturvedi, Alun D Hughes, H Rolf Jäger, M Jorge Cardoso
Sep 15, 2022
BACKGROUND AND AIMS: Risk of stroke and dementia is markedly higher in people of South Asian and African Caribbean descent than white Europeans in the UK. This is unexplained by cardiovascular risk factors (CVRF). We...
Promoting axon regeneration in the central nervous system by increasing PI3-kinase signaling.
Much research has focused on the PI3-kinase and PTEN signaling pathway with the aim to stimulate repair of the injured central nervous system. Axons in the central nervous system fail to regenerate, meaning that injuries or...
ARF6 and Rab11 as intrinsic regulators of axon regeneration.
Adult central nervous system (CNS) axons do not regenerate after injury because of extrinsic inhibitory factors, and a low intrinsic capacity for axon growth. Developing CNS neurons have a better regenerative ability, but lose...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Engaging Users for Participating in a European Data Collection Campaign with Smartphones
Researchers worldwide require valuable data to confirm and validate their models or theories. Obtaining such data, especially concerning people's behaviour, is very difficult. Although ICT technologies can facilitate the data...
Published by: IGI Global Scientific Publishing
Accelerated vascular aging
Carole H Sudre, Stefano Moriconi, Rafael Rehwald, Lorna Smith, Therese Tillin, Josephine Barnes, David Atkinson, Sébastien Ourselin, Nish Chaturvedi, Alun D Hughes, H Rolf Jäger, M Jorge Cardoso
Aug 11, 2022
Background and aims: Risk of stroke and dementia is markedly higher in people of South Asian and African Caribbean descent than white Europeans in the UK. This is unexplained by cardiovascular risk factors (CVRF). We...
Regional Regulation of Purkinje Cell Dendritic Spines by Integrins and Eph/Ephrins.
Climbing fibres and parallel fibres compete for dendritic space on Purkinje cells in the cerebellum. Normally, climbing fibres populate the proximal dendrites, where they suppress the multiple small spines typical of parallel...
Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury.
Investigating the molecular mechanisms governing developmental axon growth has been a useful approach for identifying new strategies for boosting axon regeneration after injury, with the goal of treating debilitating conditions...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
IP3 3-kinase opposes NGF driven neurite outgrowth.
Richard Eva, Dalila Bouyoucef-Cherchalli, Kalpana Patel, Peter J Cullen, George Banting
Jun 29, 2018
The inositol (1,4,5) trisphosphate 3-kinases comprise a family of enzymes (A, B, and C) that phosphorylate the calcium mobilising molecule inositol (1,4,5) trisphosphate (IP(3)) to generate inositol (1,3,4,5) tetrakisphosphate....
Actins Animals Catalysis Cell Differentiation Cell Separation Extracellular Signal-Regulated MAP Kinases Flow Cytometry Green Fluorescent Proteins Hippocampus Models Biological Nerve Growth Factor Neurites Neurons PC12 Cells Phenotype Phosphotransferases (Alcohol Group Acceptor) Rats Signal Transduction
Stock Return Determinants In Stock Market Movements
The purpose of this study was to examine the effect of Economic Value Added (EVA), Market Value Added (MVA), Residual Income (RI), Earnings Per Share (EPS) and Operating Cash Flow (OCF) on Stock Returns. Samples used in the...
economic value added Market Value Added Residual Income Earnings Per Share Operating Cash Flow Stock Return No
Published by: Indonesia Strategic Sustainability
Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS.
Elske HP Franssen, Rong-Rong Zhao, Hiroaki Koseki, Venkateswarlu Kanamarlapudi, Casper C Hoogenraad, Richard Eva, James W Fawcett
May 21, 2015
Dr. Herman L. Frick Attends Teacher Education Clinic
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Published by: Winthrop University
A Hearing Screening Protocol for Stroke Patients
Nehzat Koohi, Deborah A Vickers, Nattawan Utoomprurkporn, David J Werring, Doris-Eva Bamiou
Jul 02, 2020
Background: Auditory impairment post stroke is common and may be due to both peripheral hearing loss and or central auditory processing disorder (CAPD). When auditory impairment remains untreated, it may impact on patient...
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
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