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Remembering Ewan MacColl
Owen Holland
May 05, 2013
In this article Owen Holland examines Ewan MacColl's early work in agit-prop theatre and his later activity as a songwriter, performer, and collector in the second British folk revival. He argues that his experience in the...
Theatre Workshop agit-prop theatre performance aesthetics second folk revival politically committed cultural production
Published by: New Theatre Quarterly Journal (published by CUP)
Decoupling a tandem-repeat protein
The simple topology and modular architecture of tandem-repeat proteins such as tetratricopeptide repeats (TPRs) and ankyrin repeats makes them straightforward to dissect and redesign. Repeat-protein stability can be manipulated...
Rates of glycaemic deterioration in a real-world population with type 2 diabetes
Louise A. Donnelly, Kaixin Zhou, Alex S.F. Doney, Chris Jennison, Paul W. Franks, Ewan R. Pearson
Mar 01, 2018
Aims/hypothesis: There is considerable variability in how diabetes progresses after diagnosis. Progression modelling has largely focused on ‘time to failure’ methods, yet determining a ‘coefficient of failure’ has many...
A web-based design for occupational safety and health capability maturity indicator
Anush Poghosyan Hopes, Patrick Manu, Abdul Majeed Mahamadu, Olugbenga O. Akinade, Lamine Mahdjoubi, Alistair G.F. Gibb, Michael Behm
Feb 01, 2020
It has been established that design contributes to the occurrence of occupational injuries and illnesses in the construction sector. This has resulted in the need for designers to implement design for occupational safety and...
Decoupling a tandem-repeat protein
Abstract: The simple topology and modular architecture of tandem-repeat proteins such as tetratricopeptide repeats (TPRs) and ankyrin repeats makes them straightforward to dissect and redesign. Repeat-protein stability can be...
Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner.
Sampurna Chakrabarti, Luke A Pattison, Kaajal Singhal, James RF Hockley, Gerard Callejo, Ewan St John Smith
Nov 17, 2018
Digging behavior dorsal root ganglion neurons Inflammation Joint pain sensitization TRPV1 Animals Anti-Inflammatory Agents Non-Steroidal Arthralgia Capsaicin Cells Cultured Disease Models Animal Female Freund's Adjuvant Ganglia Spinal Hindlimb Inflammation Isoquinolines Mice Inbred C57BL Motor Activity Receptor trkA Sensory Receptor Cells TRPV Cation Channels Urea gamma-Aminobutyric Acid
Activity-dependent regulation of NMDA receptors in substantia nigra dopaminergic neurones.
N-Methyl-d-aspartate receptors (NMDARs) are Ca(2+)-permeable glutamate receptors that play a critical role in synaptic plasticity and promoting cell survival. However, overactive NMDARs can trigger cell death signalling pathways...
Rates of glycaemic deterioration in a real-world population with type 2 diabetes
Louise A. Donnelly, Kaixin Zhou, Alex S.F. Doney, Chris Jennison, Paul W. Franks, Ewan R. Pearson
Mar 01, 2018
Aims/hypothesis: There is considerable variability in how diabetes progresses after diagnosis. Progression modelling has largely focused on ‘time to failure’ methods, yet determining a ‘coefficient of failure’ has many...
Thermodynamic Rhythm
Ewan Jones
Sep 11, 2018
This essay argues that the cultural reception of thermodynamics in the late nineteenth century reformulated the concept of rhythm, in an attempt to manage, mitigate or acknowledge the problem of waste. Having demonstrated an...
Advances in understanding nociception and neuropathic pain.
Ewan St John Smith
Nov 28, 2018
Pain results from the activation of a subset of sensory neurones termed nociceptors and has evolved as a "detect and protect" mechanism. However, lesion or disease in the sensory system can result in neuropathic pain, which...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
A Combined Phenotypic-Genotypic Predictive Algorithm for In Vitro Detection of Bicarbonate
Selvi C. Ersoy, Warren E. Rose, Robin Patel, Richard A. Proctor, Henry F. Chambers, Ewan M. Harrison, Youngju Pak, Arnold S. Bayer
Sep 12, 2021
Antimicrobial susceptibility testing (AST) is routinely used to establish predictive antibiotic resistance metrics to guide the treatment of bacterial pathogens. Recently, a novel phenotype termed “bicarbonate...
A Combined Phenotypic-Genotypic Predictive Algorithm for In Vitro Detection of Bicarbonate
Selvi C Ersoy, Warren E Rose, Robin Patel, Richard A Proctor, Henry F Chambers, Ewan M Harrison, Youngju Pak, Arnold S Bayer
Oct 29, 2021
Antimicrobial susceptibility testing (AST) is routinely used to establish predictive antibiotic resistance metrics to guide the treatment of bacterial pathogens. Recently, a novel phenotype termed "bicarbonate...
Optimized design and assessment of whole genome tiling arrays.
Stefan Gräf, Fiona GG Nielsen, Stefan Kurtz, Martijn A Huynen, Ewan Birney, Henk Stunnenberg, Paul Flicek
Sep 23, 2019
MOTIVATION: Recent advances in microarray technologies have made it feasible to interrogate whole genomes with tiling arrays and this technique is rapidly becoming one of the most important high-throughput functional genomics...
Context-Dependent Energetics of Loop Extensions in a Family of Tandem-Repeat Proteins.
Consensus-designed tetratricopeptide repeat proteins are highly stable, modular proteins that are strikingly amenable to rational engineering. They therefore have tremendous potential as building blocks for biomaterials and...
A web-based design for occupational safety and health capability maturity indicator
Anush Poghosyan Hopes, Patrick Manu, Abdul Majeed Mahamadu, Olugbenga O. Akinade, Lamine Mahdjoubi, Alistair G.F. Gibb, Michael Behm
Feb 01, 2020
It has been established that design contributes to the occurrence of occupational injuries and illnesses in the construction sector. This has resulted in the need for designers to implement design for occupational safety and...
The composition and functional protein subsystems of the human nasal microbiome in granulomatosis with polyangiitis
Josef Wagner, Ewan M. Harrison, Marcos Martinez Del Pero, Beth Blane, Gert Mayer, Johannes Leierer, Seerapani Gopaluni, Mark A. Holmes, Julian Parkhill, Sharon J. Peacock, David R. W. Jayne, Andreas Kronbichler
Oct 21, 2020
Abstract: Background: Ear, nose and throat involvement in granulomatosis with polyangiitis (GPA) is frequently the initial disease manifestation. Previous investigations have observed a higher prevalence of Staphylococcus aureus...
The Evolutionary Genomics of Host Specificity in Staphylococcus aureus.
Staphylococcus aureus is an important human bacterial pathogen that has a cosmopolitan host range, including livestock, companion and wild animal species. Genomic and epidemiological studies show that S. aureus has jumped...
Bacteria Emerging Infectious Diseases host adaptation host switch mobile genetic element whole-genome sequencing Animals Bacteria evolution Molecular Genomics Host Adaptation Host Specificity Humans Interspersed Repetitive Sequences Livestock Staphylococcal Infections Staphylococcus aureus whole genome sequencing
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect the patient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and if found...
Published by: IJHS Medical Association
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
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