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Results: 570
Evaluating Stiffness of Fibreglass and Thermoplastic Splint Materials and Inter-fragmentary Motion in a Canine Tibial Fracture Model.
OBJECTIVES:  Various materials are used to construct splints for mid-diaphyseal tibial fracture stabilization. The objective of this study was to compare construct stiffness and inter-fragmentary bone motion when fibreglass (FG)...
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Structure and Organization of Nuclear Pore Proteins
Claire Atkinson
Jan 01, 0001
The nuclear pore complex (NPC) is a large macromolecular assembly that controls the flow of molecules between the nucleus and the cytoplasm. Elucidating the structure and organization of this complex will be crucial to...
Published by: Rockefeller University
Stiffness and strength of stabilized organic soils—part i/ii
This paper presents the experimental database and corresponding statistical analysis (Part I), which serves as a basis to perform the corresponding parametric analysis and machine learning modelling (Part II) of a...
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
Anubha Mahajan, Xueling Sim, Hui Jin Ng, Alisa Manning, Manuel A Rivas, Heather M Highland, Adam E Locke, Niels Grarup, Hae Kyung Im, Pablo Cingolani, Jason Flannick, Pierre Fontanillas, Christian Fuchsberger, Kyle J Gaulton, Tanya M Teslovich, N William Rayner, Neil R Robertson, Nicola L Beer, Jana K Rundle, Jette Bork-Jensen, Claes Ladenvall, Christine Blancher, David Buck, Gemma Buck, Noël P Burtt, Stacey Gabriel, Anette P Gjesing, Christopher J Groves, Mette Hollensted, Jeroen R Huyghe, Anne U Jackson, Goo Jun, Johanne Marie Justesen, Massimo Mangino, Jacquelyn Murphy, Matt Neville, Robert Onofrio, Kerrin S Small, Heather M Stringham, Ann-Christine Syvänen, Joseph Trakalo, Goncalo Abecasis, Graeme I Bell, John Blangero, Nancy J Cox, Ravindranath Duggirala, Craig L Hanis, Mark Seielstad, James G Wilson, Cramer Christensen, Ivan Brandslund, Rainer Rauramaa, Gabriela L Surdulescu, Alex SF Doney, Lars Lannfelt, Allan Linneberg, Bo Isomaa, Tiinamaija Tuomi, Marit E Jørgensen, Torben Jørgensen, Johanna Kuusisto, Matti Uusitupa, Veikko Salomaa, Timothy D Spector, Andrew D Morris, Colin NA Palmer, Francis S Collins, Karen L Mohlke, Richard N Bergman, Erik Ingelsson, Lars Lind, Jaakko Tuomilehto, Torben Hansen, Richard M Watanabe, Inga Prokopenko, Josee Dupuis, Fredrik Karpe, Leif Groop, Markku Laakso, Oluf Pedersen, Jose C Florez, Andrew P Morris, David Altshuler, James B Meigs, Michael Boehnke, Mark I McCarthy, Cecilia M Lindgren, Anna L Gloyn, T2D-GENES consortium and GoT2D consortium
Sep 09, 2016
Genome wide association studies (GWAS) for fasting glucose (FG) and insulin (FI) have identified common variant signals which explain 4.8% and 1.2% of trait variance, respectively. It is hypothesized that low-frequency and rare...
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Review of Bruno Latour, Facing Gaia: Eight Lectures on the New Climate Regime. Cambridge
Shannon O'Rourke
Jan 07, 2020
Facing Gaia: Eight Lectures on the New Climate Regime (FG, 2017) in significant ways represents an ecological application of Latour’s lifelong development of an anthropology of the moderns. Latour tells us in 2008, in an...
Biophysical Characterization of Structure and Dynamics of Nuclear Pore Complex Components
Martin Kampmann
Jan 01, 0001
The Nuclear Pore Complex (NPC) mediates nucleo-cytoplasmic transport in all eukaryotes and is among the largest cellular assemblies of proteins, called nucleoporins (nups). The details of NPC architecture, dynamics, and...
Published by: Rockefeller University
Biochemical Analysis of the Protein-Protein Interactions Involved in Karyopherin-Mediated Transport Across the Nuclear Pore Complex
Nucleocytoplasmic transport occurs through the nuclear pore complex (NPC), which in yeast is a highly symmetric ~50 MDa complex consisting of approximately 30 different proteins. Small molecules can freely exchange through the...
Published by: Rockefeller University
Review of Bruno Latour, Facing Gaia: Eight Lectures on the New Climate Regime. Cambridge
Shannon O'Rourke
Jan 07, 2020
Facing Gaia: Eight Lectures on the New Climate Regime (FG, 2017) in significant ways represents an ecological application of Latour’s lifelong development of an anthropology of the moderns. Latour tells us in 2008, in an...
Detection of <em>Candida albicans</em> DNA from blood samples using a novel electrochemical assay
The genus Candida contains a number of yeast species which are opportunistic pathogens and are associated with life-threatening infections in immunocompromised individuals. Provision of appropriate therapy relies on the rapid...
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Detection of <em>Candida albicans</em> DNA from blood samples using a novel electrochemical assay
The genus Candida contains a number of yeast species which are opportunistic pathogens and are associated with life-threatening infections in immunocompromised individuals. Provision of appropriate therapy relies on the rapid...
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How Literal is the 1972 Translation Into English of J.L. Borges' Historia Universal de la Infamia?
Marcelo Sánchez
Jan 01, 2023
This article analyzes A Universal History of Infamy, the 1972 translation into English of Historia Universal de la Infamia (hereinafter, HUI). While assessing this translation's degree of literality, the authors also...
The Making of “La Gran Familia Mexicana”
R Sánchez‐Rivera
Jun 14, 2021
This article examines the impact of Mexican eugenics on different programs relating to the familythroughout the postRevolutionary period. It deals with how Mexican elites thought about thefamily and how these discussions...
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Deciphering Master Gene Regulators and Associated Networks of Human Mesenchymal Stromal Cells
Mesenchymal Stromal Cells (MSC) are multipotent cells characterized by self-renewal, multilineage differentiation, and immunomodulatory properties. To obtain a gene regulatory profile of human MSCs, we generated a compendium of...
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Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.
Smoking is a potentially causal behavioral risk factor for type 2 diabetes (T2D), but not all smokers develop T2D. It is unknown whether genetic factors partially explain this variation. We performed genome-environment-wide...
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