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Creating and Sharing Interorganizational Knowledge Through a Supply Chain 4.0 Project
Digitalization in the supply chain involves important transformations in the relationships between supply chain partners. Studies investigating these transformations underline the need to create and share new knowledge processes...
Published by: IGI Global Scientific Publishing
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice
Delta-like ligand 4 (Dll4)-Notch signaling is essential for T cell development and alternative thymic lineage decisions. How Dll4-Notch signaling affects pro-T cell fate and thymic dendritic cell (tDC) development is unknown. We...
Autoimmunity Cell Differentiation dendritic cell pancreas islet cell insulin dependent diabetes mellitus Pancreas Western blotting Thymus Gland
Published by: Rockefeller University
Uncovering the Number and Clonal Dynamics of Mesp1 Progenitors during Heart Morphogenesis.
Samira Chabab, Fabienne Lescroart, Steffen Rulands, Navrita Mathiah, Benjamin D Simons, Cédric Blanpain
Dec 04, 2015
Epilepsy and Ecstatic Experiences
Ecstatic epilepsy is a rare form of focal epilepsy in which the aura (beginning of the seizures) consists of a blissful state of mental clarity/feeling of certainty. Such a state has also been described as a "religious" or...
Epilepsy and Ecstatic Experiences
Ecstatic epilepsy is a rare form of focal epilepsy in which the aura (beginning of the seizures) consists of a blissful state of mental clarity/feeling of certainty. Such a state has also been described as a "religious" or...
Linking Diversity and Mental Health
Niklas Schulte, Friedrich M Götz, Fabienne Partsch, Tim Goldmann, Lea Smidt, Bertolt Meyer
Jul 14, 2020
Diversity and psychological health issues at the workplace are pressing issues in today's organizations. However, research linking two fields is scant. To bridge this gap, drawing from team faultline research, social...
Common variation in EMSY and risk of breast and ovarian cancer
Patrick R Benusiglio, Fabienne Lesueur, Craig Luccarini, Joan McIntosh, Robert N Luben, Paula Smith, Alison Dunning, Douglas F Easton, Bruce AJ Ponder, Paul D Pharoah
Jun 16, 2011
BACKGROUND: EMSY could be involved in low-level susceptibility to breast and ovarian cancer. Gene amplification is seen in a proportion of breast and ovarian tumours and correlates with poor prognosis in breast cancer patients....
Adolescent Adult Aged Alleles Breast Neoplasms Case-Control Studies Chromatography High Pressure Liquid Female Genetic Predisposition to Disease genetic variation Genotype Haplotypes Homozygote Humans Linkage Disequilibrium Middle Aged Models Genetic Models Statistical Neoplasm Proteins Nuclear Proteins Ovarian Neoplasms Polymorphism Genetic Polymorphism Single Nucleotide Prognosis Repressor Proteins risk Transcriptional Activation
Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells.
Camille Martin-Gallausiaux, Pierre Larraufie, Anne Jarry, Fabienne Béguet-Crespel, Ludovica Marinelli, Florence Ledue, Frank Reimann, Hervé M Blottière, Nicolas Lapaque
Dec 20, 2018
Commensal bacteria are crucial for the development and maintenance of a healthy immune system therefore contributing to the global well-being of their host. A wide variety of metabolites produced by commensal bacteria are...
IDO-1 butyrate Gut microbiota immune gene regulation intestinal epithelial cells Bacteria Butyric Acid Caco-2 Cells Down-Regulation Epithelial Cells Female Gastrointestinal Microbiome Gene Expression Regulation Developmental Humans Indoleamine-Pyrrole 2 3 -Dioxygenase Interferon-gamma Intestinal Mucosa Male Middle Aged Receptors G-Protein-Coupled Transcription Factors
Electrical output of bryophyte microbial fuel cell systems is sufficient to power a radio or an environmental sensor.
CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.
Sharon E Miller, Signe Mathiasen, Nicholas A Bright, Fabienne Pierre, Bernard T Kelly, Nikolay Kladt, Astrid Schauss, Christien J Merrifield, Dimitrios Stamou, Stefan Höning, David J Owen
Jun 25, 2015
Cell Line Tumor Cell Membrane Cell Shape Clathrin-Coated Vesicles Coated Pits Cell-Membrane Endocytosis Epidermal Growth Factor Fatty Acid-Binding Proteins HeLa Cells Humans Liposomes Monomeric Clathrin Assembly Proteins Protein Structure Tertiary R-SNARE Proteins RNA Interference RNA Small Interfering Transferrin
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.
Sakari Vanharanta, Weiping Shu, Fabienne Brenet, A Ari Hakimi, Adriana Heguy, Agnes Viale, Victor E Reuter, James J-D Hsieh, Joseph M Scandura, Joan Massagué
Feb 13, 2020
Inactivation of the von Hippel-Lindau tumor suppressor gene, VHL, is an archetypical tumor-initiating event in clear cell renal carcinoma (ccRCC) that leads to the activation of hypoxia-inducible transcription factors (HIFs)....
Animals Base Sequence Carcinoma Renal Cell Cell Line Tumor DNA Methylation Gene Expression Regulation Neoplastic Histones Humans Hypoxia-Inducible Factor 1 Kidney Neoplasms Mice Mice Inbred NOD Mice SCID Neoplasm Metastasis Polycomb Repressive Complex 2 Receptors CXCR4 Sequence Analysis DNA Transcription Factors Von Hippel-Lindau Tumor Suppressor Protein
Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq.
Fabienne Lescroart, Xiaonan Wang, Xionghui Lin, Benjamin Swedlund, Souhir Gargouri, Adriana Sànchez-Dànes, Victoria Moignard, Christine Dubois, Catherine Paulissen, Sarah Kinston, Berthold Göttgens, Cédric Blanpain
Mar 20, 2018
Mouse heart development arises from Mesp1-expressing cardiovascular progenitors (CPs) that are specified during gastrulation. The molecular processes that control early regional and lineage segregation of CPs have been unclear....
Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development.
Fabienne Lescroart, Samira Chabab, Xionghui Lin, Steffen Rulands, Catherine Paulissen, Annie Rodolosse, Herbert Auer, Younes Achouri, Christine Dubois, Antoine Bondue, Benjamin D Simons, Cédric Blanpain
Sep 30, 2014
Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS)
Finbar J K O'Callaghan, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin R. Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew A. Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity, John P. Osborne
Jan 01, 2017
Background: Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We aimed to assess...
Azulene-Derived Fluorescent Probe for Bioimaging
Lloyd C. Murfin, Maria Weber, Sang Jun Park, Won Tae Kim, Carlos M. Lopez-Alled, Claire L. McMullin, Fabienne Pradaux-Caggiano, Catherine L. Lyall, Gabriele Kociok-Köhn, Jannis Wenk, Steven D. Bull, Juyoung Yoon, Hwan Myung Kim, Tony D. James, Simon E. Lewis
Dec 11, 2019
Two-photon fluorescence microscopy has become an indispensable technique for cellular imaging. Whereas most two-photon fluorescent probes rely on well-known fluorophores, here we report a new fluorophore for bioimaging...
The underlying etiology of infantile spasms (West syndrome)
John P. Osborne, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin R. Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity, Finbar J. K. O'Callaghan, on behalf of the participating investigators
Sep 07, 2019
Objective
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
Methods
Identification of the underlying etiology and...
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
Methods
Identification of the underlying etiology and...
Common ERBB2 polymorphisms and risk of breast cancer in a white British population
Patrick R Benusiglio, Fabienne Lesueur, Craig Luccarini, Donald M Conroy, Mitul Shah, Douglas F Easton, Nick E Day, Alison M Dunning, Paul D Pharoah, Bruce AJ Ponder
Jun 17, 2011
INTRODUCTION: About two-thirds of the excess familial risk associated with breast cancer is still unaccounted for and may be explained by multiple weakly predisposing alleles. A gene thought to be involved in low-level...
Encephalopathy induced by Alzheimer brain inoculation in a non-human primate.
Charlotte Gary, Suzanne Lam, Anne-Sophie Hérard, James E Koch, Fanny Petit, Pauline Gipchtein, Stephen J Sawiak, Raphaëlle Caillierez, Sabiha Eddarkaoui, Morvane Colin, Fabienne Aujard, Jean-Philippe Deslys, French Neuropathology Network, Emmanuel Brouillet, Luc Buée, Emmanuel E Comoy, Fabien Pifferi, Jean-Luc Picq, Marc Dhenain
Sep 03, 2020
Alzheimer's disease is characterized by cognitive alterations, cerebral atrophy and neuropathological lesions including neuronal loss, accumulation of misfolded and aggregated β-amyloid peptides (Aβ) and tau proteins. Iatrogenic...
Alzheimer’s disease Cerebral atrophy COGNITIVE IMPAIRMENT Microcebus murinus MOUSE Neurodegenerative disease Neuronal function Prion tau pathology β-Amyloid pathology Alzheimer Disease Animals Brain Brain Diseases Cheirogaleidae Electroencephalography Female Humans Magnetic Resonance Imaging Male Mice Mice Transgenic Primates Species Specificity
A rapidly-reversible absorptive and emissive vapochromic Pt(II) pincer based chemical sensor
Mathew Bryant, Jonathan Skelton, Lauren Hatcher, Clare Stubbs, Elena Madrid, Anuradha R. Pallipurath, Lynne Thomas, Christopher Woodall, Jeppe Christensen, Sara Fuertes, Thomas Robinson, Christine M. Beavers, Simon J Teat, Mark R Warren, Fabienne Pradaux-Caggiano, Aron Walsh, Frank Marken, David Carbery, Stephen Parker, Neil B. Mckeown, Richard Malpass-Evans, Mariolino Carta, Paul Raithby
Nov 27, 2017
Selective, robust and cost-effective chemical sensors for detecting small volatile-organic compounds (VOCs) have widespread applications in industry, healthcare and environmental monitoring. Here we design a Pt(II) pincer-type...
A dataset of non-pharmaceutical interventions on SARS-CoV-2 in Europe.
George Altman, Janvi Ahuja, Joshua Teperowski Monrad, Gurpreet Dhaliwal, Charlie Rogers-Smith, Gavin Leech, Benedict Snodin, Jonas B Sandbrink, Lukas Finnveden, Alexander John Norman, Sebastian B Oehm, Julia Fabienne Sandkühler, Jan Kulveit, Seth Flaxman, Yarin Gal, Swapnil Mishra, Samir Bhatt, Mrinank Sharma, Sören Mindermann, Jan Markus Brauner
May 09, 2022
During the second half of 2020, many European governments responded to the resurging transmission of SARS-CoV-2 with wide-ranging non-pharmaceutical interventions (NPIs). These efforts were often highly targeted at the regional...
A dataset of non-pharmaceutical interventions on SARS-CoV-2 in Europe.
George Altman, Janvi Ahuja, Joshua Teperowski Monrad, Gurpreet Dhaliwal, Charlie Rogers-Smith, Gavin Leech, Benedict Snodin, Jonas B Sandbrink, Lukas Finnveden, Alexander John Norman, Sebastian B Oehm, Julia Fabienne Sandkühler, Jan Kulveit, Seth Flaxman, Yarin Gal, Swapnil Mishra, Samir Bhatt, Mrinank Sharma, Sören Mindermann, Jan Markus Brauner
Apr 01, 2022
During the second half of 2020, many European governments responded to the resurging transmission of SARS-CoV-2 with wide-ranging non-pharmaceutical interventions (NPIs). These efforts were often highly targeted at the regional...
A survey by the European Society of Breast Imaging on the implementation of breast diffusion-weighted imaging in clinical practice.
Roberto Lo Gullo, Varadan Sevilimedu, Pascal Baltzer, Denis Le Bihan, Julia Camps-Herrero, Paola Clauser, Fiona J Gilbert, Mami Iima, Ritse M Mann, Savannah C Partridge, Andrew Patterson, Eric E Sigmund, Sunitha Thakur, Fabienne E Thibault, Laura Martincich, Katja Pinker, EUSOBI International Breast Diffusion-Weighted Imaging working group
Jun 07, 2022
OBJECTIVES: To perform a survey among all European Society of Breast Imaging (EUSOBI) radiologist members to gather representative data regarding the clinical use of breast DWI. METHODS: An online questionnaire was developed by...
The underlying etiology of infantile spasms (West syndrome)
John P. Osborne, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin R. Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity, Finbar J. K. O'Callaghan, on behalf of the participating investigators
Sep 07, 2019
Objective
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
Methods
Identification of the underlying etiology and...
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
Methods
Identification of the underlying etiology and...
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