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Results: 280
Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System
The peripheral nervous system (PNS) has a remarkable regenerative capacity in comparison to the central nervous system (CNS), a phenomenon that is impaired during ageing. The ability of PNS axons to regenerate after...
Jose A Gomez-Sanchez, Nikiben Patel, Fernanda Martirena, Shaline V Fazal, Clara Mutschler, Hugo Cabedo
Mar 11, 2022
Hyperosmotic stress induces cell-dependent aggregation of α-synuclein.
Alexandra MC Fragniere, Simon RW Stott, Shaline V Fazal, Maria Andreasen, Kirsten Scott, Roger A Barker
Jan 17, 2019
Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System
Jose Antonio Gomez-Sanchez, Nikiben Patel, Fernanda Martirena, Shaline V Fazal, Clara Mutschler, Hugo Cabedo
Apr 24, 2022
Perceptions of Top Management Officials Regarding Operative Factors of TQM at Public Sector Universities of Pakistan
This study sought to explore the perceptions of vice-chancellors, registrars, and deans regarding the operative factors of total quality management at public sector universities of Pakistan. All the top management officials of...
Total quality management Vision and Mission Curriculum Design and Delivery Monitoring and Performances Education
Published by: Department of History, University of Karachi
Entrepreneurial Traits, Competency, Performance, and Sustainability of Micro-Enterprises in Kelantan, Malaysia
This study examined the effects of locus of control, tolerance of ambiguity, vision, persistence, and resilience on entrepreneurial competency, performance, and sustainability among micro-enterprises in Kelantan, Malaysia....
Published by: IGI Global Scientific Publishing
Design and development of a nozzle-free electrospinning device for the high-throughput production of biomaterial nanofibers
Muhammad Waqas, Antonios Keirouz, Maria Kana Sanira Putri, Faraz Fazal, Francisco Javier Diaz Sanchez, Dipa Ray, Vasileios Koutsos, Norbert Radacsi
Jun 30, 2021
This technical note provides a step-by-step guide for the design and construction of a temperature-controlled nozzle-free electrospinning device. The equipment uses a rotating mandrel partially immersed within a polymer...
Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease
Danish Saleheen, Philip C Haycock, Wei Zhao, Asif Rasheed, Adam Taleb, Atif Imran, Shahid Abbas, Faisal Majeed, Saba Akhtar, Nadeem Qamar, Khan Shah Zaman, Zia Yaqoob, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Nadeem Hayyat Mallick, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-Ur-Rehman Memon, Khalid Mahmood, Naveeduddin Ahmed, Philippe Frossard, Sotirios Tsimikas, Joseph L Witztum, Santica Marcovina, Manjinder Sandhu, Daniel J Rader, John Danesh
Nov 15, 2017
BACKGROUND: The lipoprotein(a) pathway is a causal factor in coronary heart disease. We used a genetic approach to distinguish the relevance of two distinct components of this pathway, apolipoprotein(a) isoform size and...
Whole-Genome Sequences of Five Strains of Kocuria rosea, NCTC2676, NCTC7514, NCTC7512, NCTC7528, and NCTC7511.
Jake D Turnbull, Julie E Russell, Mohammed-Abbas Fazal, Nicholas E Grayson, Ana Deheer-Graham, Karen Oliver, Nancy Holroyd, Julian Parkhill, Sarah Alexander
Nov 13, 2019
Kocuria rosea is a Gram-positive coccus found in the environment and within normal human skin microbiota, and more recently, it has been potentially implicated as an opportunistic pathogen. Here, we describe the genome sequences...
Complete Whole-Genome Sequences of Two Raoultella terrigena Strains, NCTC 13097 and NCTC 13098, Isolated from Human Cases.
Mohammed-Abbas Fazal, Sarah Alexander, Nicholas E Grayson, Ana Deheer-Graham, Karen Oliver, Nancy Holroyd, Julian Parkhill, Julie E Russell
Aug 20, 2019
Raoultella terrigena is a bacterial species associated with soil and aquatic environments; however, sporadic cases of opportunistic disease in humans have been reported. Here, we report the first two complete genome sequences...
Complete Whole-Genome Sequence of Salmonella enterica subsp. enterica Serovar Java NCTC5706.
Mohammed-Abbas Fazal, Sarah Alexander, Edward Burnett, Ana Deheer-Graham, Karen Oliver, Nancy Holroyd, Julian Parkhill, Julie E Russell
Sep 06, 2019
Salmonellae are a significant cause of morbidity and mortality globally. Here, we report the first complete genome sequence for Salmonella enterica subsp. enterica serovar Java strain NCTC5706. This strain is of historical...
Complete Whole-Genome Sequence of Haemophilus haemolyticus NCTC 10839.
Mohammed-Abbas Fazal, Sarah Alexander, Nicholas E Grayson, Ana Deheer-Graham, Karen Oliver, Nancy Holroyd, Julian Parkhill, Julie E Russell
Jul 25, 2019
Haemophilus haemolyticus is a Gram-negative bacterium that is a commensal of the respiratory tract in humans. Here, we report the complete genome sequence available for Haemophilus haemolyticus strain NCTC 10839, which was...
Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain
Wei‐Li Kuan, Maha Alfaidi, Catherine B Horne, Benjamin Vallin, Sarah Fox, Shaline V Fazal, Caroline H Williams‐Gray, Roger A Barker
Nov 02, 2022
Selective loss of discrete neuronal populations is a prominent feature of many neurodegenerative conditions, but the molecular basis of this is poorly understood. A central role of α‐synuclein in the selective neurodegeneration...
Design and development of a nozzle-free electrospinning device for the high-throughput production of biomaterial nanofibers
Muhammad Waqas, Antonios Keirouz, Maria Kana Sanira Putri, Faraz Fazal, Francisco Javier Diaz Sanchez, Dipa Ray, Vasileios Koutsos, Norbert Radacsi
Jun 30, 2021
This technical note provides a step-by-step guide for the design and construction of a temperature-controlled nozzle-free electrospinning device. The equipment uses a rotating mandrel partially immersed within a polymer...
Contribution of Abdul Sattar Khan Niazi for Originating the Punjab Muslim Student Federation and its manifesto of "Pakistan Khilaphat Scheme"
During the movement for Pakistan, the students played a crucial role. Particularly the efforts of students of Punjab contributed to turn the politics of Punjab, which was totally in the hand of Unionist Party and its landlords...
Published by: Department of History, University of Karachi
Quest for an Islamic Welfare State and Endeavors of Small Religious Parties
After 9/11, there is a heated debate on the political and economic aspects of Islam. It is believed that Islamic socio economic order, being an effective part of Islamic code of life, finds solution to everyday problems which a...
Published by: Department of History, University of Karachi
Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
Eric L Harshfield, Eric B Fauman, David Stacey, Dirk S Paul, Daniel Ziemek, Rachel M Y Ong, John Danesh, Adam S Butterworth, Asif Rasheed, Taniya Sattar, Zameer-ul-Asar, Imran Saleem, Zoubia Hina, Unzila Ishtiaq, Nadeem Qamar, Nadeem Hayat Mallick, Zia Yaqub, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-Ur-Rehman Memon, Anjum Jalal, Shahid Abbas, Philippe Frossard, Danish Saleheen, Angela M Wood, Julian L Griffin, Albert Koulman
Oct 13, 2021
Published by: BMC medicine
Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci
Eric L. Harshfield, Eric B. Fauman, David Stacey, Dirk S. Paul, Daniel Ziemek, Rachel M. Y. Ong, John Danesh, Adam S. Butterworth, Asif Rasheed, Taniya Sattar, Zameer-ul-Asar, Imran Saleem, Zoubia Hina, Unzila Ishtiaq, Nadeem Qamar, Nadeem Hayat Mallick, Zia Yaqub, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-Ur-Rehman Memon, Anjum Jalal, Shahid Abbas, Philippe Frossard, Danish Saleheen, Angela M. Wood, Julian L. Griffin, Albert Koulman
Sep 10, 2021
Addressing Noise and Class Imbalance Problems in Heterogeneous Cross-Project Defect Prediction
When a software project either lacks adequate historical data to build a defect prediction (DP) model or is in the initial phases of development, the DP model based on related source project's defect data might be used. This...
Published by: IGI Global Scientific Publishing
Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
Eric L Harshfield, Eric B Fauman, David Stacey, Dirk S Paul, Daniel Ziemek, Rachel MY Ong, John Danesh, Adam S Butterworth, Asif Rasheed, Taniya Sattar, Zameer-ul-Asar, Imran Saleem, Zoubia Hina, Unzila Ishtiaq, Nadeem Qamar, Nadeem Hayat Mallick, Zia Yaqub, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-Ur-Rehman Memon, Anjum Jalal, Shahid Abbas, Philippe Frossard, Danish Saleheen, Angela M Wood, Julian L Griffin, Albert Koulman
Sep 02, 2021
BACKGROUND: Genetic, lifestyle, and environmental factors can lead to perturbations in circulating lipid levels and increase the risk of cardiovascular and metabolic diseases. However, how changes in individual lipid species...
An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.
Eric L Harshfield, Albert Koulman, Daniel Ziemek, Luke Marney, Eric B Fauman, Dirk S Paul, David Stacey, Asif Rasheed, Jung-Jin Lee, Nabi Shah, Sehrish Jabeen, Atif Imran, Shahid Abbas, Zoubia Hina, Nadeem Qamar, Nadeem Hayyat Mallick, Zia Yaqoob, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Syed Zahed Rasheed, Fazal-Ur-Rehman Memon, Irshad Hussain Qureshi, Muhammad Ishaq, Philippe Frossard, John Danesh, Danish Saleheen, Adam S Butterworth, Angela M Wood, Julian L Griffin
Mar 28, 2019
Direct infusion high-resolution mass spectrometry (DIHRMS) is a novel, high-throughput approach to rapidly and accurately profile hundreds of lipids in human serum without prior chromatography, facilitating in-depth lipid...
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