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Cancer associated fibroblast FAK regulates malignant cell metabolism
Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S. H. Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E. Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie Baker, Marina Roy-Luzarraga, Trevor A. Graham, Julie Foster, Yu Wang, James J. Campbell, Rajinder Singh, Penglie Zhang, Thomas J. Schall, Frances R. Balkwill, Jane Sosabowski, Pedro R. Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Mar 10, 2021
Abstract: Emerging evidence suggests that cancer cell metabolism can be regulated by cancer-associated fibroblasts (CAFs), but the mechanisms are poorly defined. Here we show that CAFs regulate malignant cell metabolism through...
Cancer associated fibroblast FAK regulates malignant cell metabolism.
Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S H Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie Baker, Marina Roy-Luzarraga, Trevor A Graham, Julie Foster, Yu Wang, James J Campbell, Rajinder Singh, Penglie Zhang, Thomas J Schall, Frances R Balkwill, Jane Sosabowski, Pedro R Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Apr 11, 2020
Emerging evidence suggests that cancer cell metabolism can be regulated by cancer-associated fibroblasts (CAFs), but the mechanisms are poorly defined. Here we show that CAFs regulate malignant cell metabolism through pathways...
Published by: Nature Communications
Cancer associated fibroblast FAK regulates malignant cell metabolism.
Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana SH Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie Baker, Marina Roy-Luzarraga, Trevor A Graham, Julie Foster, Yu Wang, James J Campbell, Rajinder Singh, Penglie Zhang, Thomas J Schall, Frances R Balkwill, Jane Sosabowski, Pedro R Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Mar 11, 2020
Emerging evidence suggests that cancer cell metabolism can be regulated by cancer-associated fibroblasts (CAFs), but the mechanisms are poorly defined. Here we show that CAFs regulate malignant cell metabolism through pathways...
Animals Breast Neoplasms Cancer-Associated Fibroblasts Cell Line Tumor Cell Proliferation Chemokines Female Focal Adhesion Protein-Tyrosine Kinases Glycolysis Humans Male Metabolic Networks and Pathways Mice Inbred C57BL Neoplasms Pancreatic Neoplasms Phosphoproteins Stromal Cells Survival Analysis Xenograft Model Antitumor Assays