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Metaphysics as a Fundamental Poise
Francisco Vicente Galán Vélez
Mar 16, 2022
Francisco Vicente Galán Vélez is a full-time professor in the philosophy department at the Universidad Iberoamericana in Mexico City. He oversaw the translation of Insight: Estudio sobre la comprensión humana, trad. Francisco...
Published by: Memorial University of Newfoundland
Metaphysics as a Fundamental Poise
Francisco Vicente Galán Vélez
Mar 16, 2022
Francisco Vicente Galán Vélez is a full-time professor in the philosophy department at the Universidad Iberoamericana in Mexico City. He oversaw the translation of Insight: Estudio sobre la comprensión humana, trad. Francisco...
Published by: Memorial University of Newfoundland
Decidualisation and placentation defects are a major cause of age-related reproductive decline.
Laura Woods, Vicente Perez-Garcia, Jens Kieckbusch, Xiaoqiu Wang, Francesco DeMayo, Francesco Colucci, Myriam Hemberger
Dec 17, 2018
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Jul 28, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
human Placenta trophoblast MOUSE trophoblast invasion developmental biology Stem Cells Epithelial-Mesenchymal Transition Regenerative Medicine stem cell self-renewal CRISPR gene editing
Published by: eLife
Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B
Abstract DNA methylation is a repressive epigenetic modification that is essential for development, exemplified by the embryonic and perinatal lethality observed in mice lacking de novo DNA...
Simon Andrews, Christel Krueger, Maravillas Mellado-Lopez, Myriam Hemberger, Wendy Dean, Vicente Perez-Garcia, Courtney W Hanna
Jan 23, 2023
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Jun 25, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells.
Stephanie Chrysanthou, Claire E Senner, Laura Woods, Elena Fineberg, Hanneke Okkenhaug, Sarah Burge, Vicente Perez-Garcia, Myriam Hemberger
Jun 20, 2019
The ten-eleven translocation (TET) proteins are well known for their role in maintaining naive pluripotency of embryonic stem cells. Here, we demonstrate that, jointly, TET1 and TET2 also safeguard the self-renewal potential of...
TET proteins Cell Cycle DIFFERENTIATION endoreduplication Mitosis self-renewal trophoblast giant cells trophoblast stem cells Animals Cell Cycle Cell Line Cell Nucleus Shape Centrosome Cyclin B1 endoreduplication Epithelial Cells Epithelial-Mesenchymal Transition Gene Expression Regulation Gene Knockout Techniques Humans Polyploidy Protein Stability Proto-Oncogene Proteins Stem Cells Trophoblasts
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Sep 05, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
CRISPR gene editing developmental biology Epithelial-Mesenchymal Transition human MOUSE Placenta Regenerative Medicine stem cell self-renewal Stem Cells trophoblast trophoblast invasion Animals Cell Differentiation Epithelial-Mesenchymal Transition Gene Expression Regulation Humans Mice Repressor Proteins Trophoblasts Tumor Suppressor Proteins Ubiquitin Thiolesterase
Exploring the perceptual inabilities of Eurasian jays (Garrulus glandarius) using magic effects.
In recent years, scientists have begun to use magic effects to investigate the blind spots in our attention and perception [G. Kuhn, Experiencing the Impossible: The Science of Magic (2019); S. Macknik, S. Martinez-Conde, S....
Differential Stability of Aurein 1.2 Pores in Model Membranes of Two Probiotic Strains
Aurein 1.2 is an antimicrobial peptide from the skin secretion of an Australian frog. In previous experimental work, we reported a differential action of aurein 1.2 on two probiotic strains Lactobacillus delbrueckii subsp....
International evaluation of an AI system for breast cancer screening.
Scott Mayer McKinney, Marcin Sieniek, Varun Godbole, Jonathan Godwin, Natasha Antropova, Hutan Ashrafian, Trevor Back, Mary Chesus, Greg S Corrado, Ara Darzi, Mozziyar Etemadi, Florencia Garcia-Vicente, Fiona J Gilbert, Mark Halling-Brown, Demis Hassabis, Sunny Jansen, Alan Karthikesalingam, Christopher J Kelly, Dominic King, Joseph R Ledsam, David Melnick, Hormuz Mostofi, Lily Peng, Joshua Jay Reicher, Bernardino Romera-Paredes, Richard Sidebottom, Mustafa Suleyman, Daniel Tse, Kenneth C Young, Jeffrey De Fauw, Shravya Shetty
Nov 22, 2019
Differential Stability of Aurein 1.2 Pores in Model Membranes of Two Probiotic Strains
Aurein 1.2 is an antimicrobial peptide from the skin secretion of an Australian frog. In previous experimental work, we reported a differential action of aurein 1.2 on two probiotic strains Lactobacillus delbrueckii subsp....
XVIIth Little Brain Big Brain
Little Brain Big Brain is a biannual meeting organized and attended by young investigators. Since its inception in 1989, this meeting has brought together promising junior researchers in neurogastroenterology. The XVIIth meeting...
Structural evidence of quercetin multi-target bioactivity
Diego Carvalho, Margot Paulino, Fabio Polticelli, Florencia Arredondo, Robert J Williams, Juan A. Abin-Carriquiry
Jun 19, 2017
The ubiquitous flavonoid quercetin is broadly recognized for showing diverse biological and health-promoting effects, such as anti-cancer, anti-inflammatory and cytoprotective activities. The therapeutic potential of quercetin...
Emergent analysis and dissemination within participatory research
Authentic participation involving jointly undertaken analysis of data and dissemination of findings is rarely evident in participatory research involving disabled people. This paper examines analysis and dissemination which...
A participatory approach to the evaluation of participatory museum research projects
In this paper we will describe, justify and critique a participatory approach that we have developed in order to evaluate the success of a participatory research project that was exploring ways of making museum learning...
Distribution of Trapped Magnetic Flux in Superconducting Stacks Magnetised by Angled Field
Abstract: Some novel energy applications require the use of complex shapes of stacks of superconducting tapes as trapped-flux magnets. A trapped-flux magnet magnetised in a superconducting motor may experience an angled...
Structural evidence of quercetin multi-target bioactivity
Diego Carvalho, Margot Paulino, Fabio Polticelli, Florencia Arredondo, Robert J Williams, Juan A. Abin-Carriquiry
Jun 19, 2017
The ubiquitous flavonoid quercetin is broadly recognized for showing diverse biological and health-promoting effects, such as anti-cancer, anti-inflammatory and cytoprotective activities. The therapeutic potential of quercetin...
Heat extraction from HTS tape stacks applied in a superconducting motor in different cooling conditions
Lukasz Tomkow, Nikolay Mineev, Anis Smara, Vicente Climente-Alarcon, Bartek A. Glowacki
Jun 19, 2020
Abstract: The heat is generated inside the stack of superconducting tapes mounted on the surface of the electrical machine rotor during its operation and magnetization. Cooling of such stack presents challenges because of the...
HPG pore
BACKGROUND: The use of nanopore technologies is expected to spread in the future because they are portable and can sequence long fragments of DNA molecules without prior amplification. The first nanopore sequencer available, the...
Emergent analysis and dissemination within participatory research
Authentic participation involving jointly undertaken analysis of data and dissemination of findings is rarely evident in participatory research involving disabled people. This paper examines analysis and dissemination which...
Brodie's Abscesses Can Stimulate the Growth Plate in Children.
Introduction: We present a series of children with lower limb Brodie's abscesses (subacute osteomyelitis) with subsequent deformities. Method: A retrospective examination of the paediatric bone and joint infection database from...
Mapping the expression of transient receptor potential channels across murine placental development
Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens
Jun 26, 2021
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