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Pharmacogenomics and the Yin/Yang actions of ginseng
In Chinese medicine, ginseng (Panax ginseng C.A. Meyer) has long been used as a general tonic or an adaptogen to promote longevity and enhance bodily functions. It has also been claimed to be effective in combating stress...
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A novel deep intronic variant strongly associates with Alkaptonuria.
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
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A novel deep intronic variant strongly associates with Alkaptonuria.
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
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Balancing the yin and yang
S Tang, S Nadkarni, L-Q WEI, SX Zhang
Oct 15, 2020
This paper offers a novel theoretical account of why and when top management team (TMT) gender diversity lends strategic advantage. Building on social role theory, we develop a moderated-mediation model showing: a) TMT...
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Designed beta-hairpins inhibit LDH5 oligomerization and enzymatic activity
Lactate dehydrogenase 5 (LDH5) is overexpressed in aggressive and metastatic tumors and is an attractive target for anticancer therapy. Small molecule drugs have been developed to target the substrate and/or the cofactor sites...
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Designed beta-hairpins inhibit LDH5 oligomerization and enzymatic activity
Lactate dehydrogenase 5 (LDH5) is overexpressed in aggressive and metastatic tumors and is an attractive target for anticancer therapy. Small molecule drugs have been developed to target the substrate and/or the cofactor sites...
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Development of a sensitive multiplexed open circuit potential system for the detection of prostate cancer biomarkers

We report the development of a sensitive label-free, cost-effective detection system with simultaneous multi-channel measurement of open circuit potential (OCP) variations for the detection of prostate specific antigen (PSA)....

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Development of a sensitive multiplexed open circuit potential system for the detection of prostate cancer biomarkers

We report the development of a sensitive label-free, cost-effective detection system with simultaneous multi-channel measurement of open circuit potential (OCP) variations for the detection of prostate specific antigen (PSA)....

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Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care
Abstract: Bladder and kidney cancer are the 10th and 7th most common cancers in the United Kingdom (UK). They present with symptoms that are typically investigated via the same diagnostic pathway. However, diagnosing these...
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Multimodal electrochemical and nanoplasmonic biosensors using ferrocene crowned nanoparticles for kinase drug discovery applications
The use of on-chip multimodal sensing approaches is very promising towards integrated biosensing systems, which measure different parameters involved in biomolecular interactions and provide automated validation of true...
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Multimodal electrochemical and nanoplasmonic biosensors using ferrocene crowned nanoparticles for kinase drug discovery applications
The use of on-chip multimodal sensing approaches is very promising towards integrated biosensing systems, which measure different parameters involved in biomolecular interactions and provide automated validation of true...
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Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's...
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Making Waves

The presence of SARS-CoV-2 RNA in wastewater was first reported in March 2020. Over the subsequent months, the potential for wastewater surveillance to contribute to COVID-19 mitigation programmes has been the focus of...

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Emerging Auditory Selectivity in the Caudomedial Neostriatum of the Zebra Finch Songbird
Caroline Wan-Yin Ang
Jan 01, 0001
The ability to identify and interpret auditory stimuli from the environmental milieu is of particular importance in species that communicate using learned vocalizations. By chronically recording multiunit neuronal responses in...
Published by: Rockefeller University

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