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COVID-19, the first pandemic in the post-genomic era.
The scale of the international efforts to sequence SARS-CoV-2 genomes is unprecedented. Early availability of genomes allowed rapid characterisation of the virus, thus kickstarting many highly successful vaccine development...
Published by: Current opinion in virology
A Go/No-Go Decision-Making Model Based on Risk and Multi-Criteria Techniques for Project Selection
The realization of infrastructures and the deployment of processes can follow project formalism. Generally, a project goes through a design and a realization phase. Between these two phases, there is a crucial milestone...
Published by: IGI Global Scientific Publishing
Does Addictive Pleasure at Work and Building a Personal IS on One's Smartphone Lead to Problematic Smartphone Dependency?
Using a sample of 848 workers in France, this article aims to explain problematic smartphone dependency, a behavior considered to have negative consequences for sufferers in the context of work. It examines whether and how...
Published by: IGI Global Scientific Publishing
The Implications of Schelling’s Metaphysics of Contingency for Phenomenology
Kyla Bruff
Aug 29, 2018
In Ecstasy of Reason, Jean-François Courtine states that F.W.J. Schelling’s late, “positive philosophy” is “not a sublime ground of being as a whole, but the contrary itself of a ground, the attempt of a phenomenology of … the...
Published by: Memorial University Libraries
Rates of vaccine evolution show strong effects of latency
Lucy A Weinert, Daniel P Depledge, Samit Kundu, Anne A Gershon, Richard A Nichols, Francois Balloux, John J Welch, Judith Breuer
May 22, 2015
Computer simulations reveal motor properties generating stable antiparallel microtubule interactions.
François Nédélec
Jul 30, 2020
An aster of microtubules is a set of flexible polar filaments with dynamic plus ends that irradiate from a common location at which the minus ends of the filaments are found. Processive soluble oligomeric motor complexes can...
The Implications of Schelling’s Metaphysics of Contingency for Phenomenology
Kyla Bruff
Aug 29, 2018
In Ecstasy of Reason, Jean-François Courtine states that F.W.J. Schelling’s late, “positive philosophy” is “not a sublime ground of being as a whole, but the contrary itself of a ground, the attempt of a phenomenology of … the...
Published by: Memorial University Libraries
Anthropogenic stressors impact fish sensory development and survival via thyroid disruption.
Marc Besson, William E Feeney, Isadora Moniz, Loïc François, Rohan M Brooker, Guillaume Holzer, Marc Metian, Natacha Roux, Vincent Laudet, David Lecchini
Jul 28, 2021
What Lessons Can Be Learned for the Agroecological Transition From the Use of Social Media in Preventive Medicine?
In agriculture, web-based social media are increasingly used to share knowledge concerning best practices. One goal of agroecology is to reduce the use of synthetic chemical inputs. Agroecology represents a contrast with...
Published by: IGI Global Scientific Publishing
FTT:Power
Jean-François Mercure
Aug 25, 2011
Makerspaces
The emergence of the makerspace movement offers tremendous potential to transform learning. Learning by making, while ancient in practice, has evolved due to the development and confluence of developments in computing...
Educational Technologies Education Educational Technologies Computer Science and Information Technology Media and Communications
Published by: IGI Global Scientific Publishing
Membrane Mechanics of Endocytosis in Cells with Turgor.
Endocytosis is an essential process by which cells internalize a piece of plasma membrane and material from the outside. In cells with turgor, pressure opposes membrane deformations, and increases the amount of force that has to...
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
Adjuvants are critical for the success of vaccines. Agonists of microbial pattern recognition receptors (PRRs) are promising new adjuvant candidates. A mechanism through which adjuvants enhance immune responses is to stimulate...
carboxymethylcellulose sod nium Gene Expression Cytokines interferon Signal Transduction virus vaccine
Published by: Rockefeller University
The Cambridge Experiment
Since the latter part of 19th century photography has played a central role in the development of architecture for its persuasive visual impact. But, despite this clear interaction, there is still reluctance from scholars in...
Suffering and Ipseity in Michel Henry
Jean-François Lavigne
Dec 19, 2016
The double expansion that Husserl’s phenomenology imposed on subjectiveexperience posed, among other difficulties, a new and particularly difficultproblem for Husserl; that of the trans-temporal identity of the...
Published by: Memorial University of Newfoundland
Amplification of actin polymerization forces.
The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple...
Suffering and Ipseity in Michel Henry
Jean-François Lavigne
Dec 19, 2016
The double expansion that Husserl’s phenomenology imposed on subjectiveexperience posed, among other difficulties, a new and particularly difficultproblem for Husserl; that of the trans-temporal identity of the...
Published by: Memorial University of Newfoundland
Force- and length-dependent catastrophe activities explain interphase microtubule organization in fission yeast.
The cytoskeleton is essential for the maintenance of cell morphology in eukaryotes. In fission yeast, for example, polarized growth sites are organized by actin, whereas microtubules (MTs) acting upstream control where growth...
Parameterised branching processes
Let (Zn,n≥0) be a supercritical Galton–Watson process whose offspring distribution μ has mean λ>1 and is such that ∫xlog+(x)dμ(x)<+∞. According to the famous Kesten & Stigum theorem...
Mechanism of nuclear movements in a multinucleated cell.
Multinucleated cells are important in many organisms, but the mechanisms governing the movements of nuclei sharing a common cytoplasm are not understood. In the hyphae of the plant pathogenic fungus Ashbya gossypii, nuclei move...
Visualizing the functional architecture of the endocytic machinery.
Clathrin-mediated endocytosis is an essential process that forms vesicles from the plasma membrane. Although most of the protein components of the endocytic protein machinery have been thoroughly characterized, their...
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