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A trip down memory lane with Retrovirology.
Monsef Benkirane, Ben Berkhout, Persephone Borrow, Ariberto Fassati, Masahiro Fujii, J Victor Garcia-Martinez, D Margolis, Monique Nijhuis, Leslie Parent, Klaus Strebel, François Venter, Frank Kirchhoff, Andrew Lever, Susan Ross, Johnson Mak
Nov 20, 2019
Fifteen years ago, Retrovirology was amongst the first open-access journals to be established through Biomed Central, instigated by our late Founding Editor Dr. Kuan-Teh Jeang. Since then, in what seemed like a rather daring...
Parasite co-infection
Laboratory studies of pathogens aim to limit complexity in order to disentangle the important parameters contributing to an infection. However, pathogens rarely exist in isolation, and hosts may sustain co-infections with...
How to spare half a planet.
James Watson and Oscar Venter discuss the practicalities of conserving half of Earth's terrestrial ecosystems (Nature 550, 48-49; 2017). But could the non-conserved half be sufficient to support the growing food needs of the...
Parasite co-infection
Laboratory studies of pathogens aim to limit complexity in order to disentangle the important parameters contributing to an infection. However, pathogens rarely exist in isolation, and hosts may sustain co-infections with...
Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore.
Saeed Seyedmohammad, Natalia Alveal Fuentealba, Robert AJ Marriott, Tom A Goetze, J Michael Edwardson, Nelson P Barrera, Henrietta Venter
Mar 02, 2016
Parasite co-infection
Laboratory studies of pathogens aim to limit complexity in order to disentangle the important parameters contributing to an infection. However, pathogens rarely exist in isolation, and hosts may sustain co-infections with...
The Innerworkings of Digital Storytelling
Traditionally, storytelling was used for entertainment and the transfer of know-how. The advent of digital media gave rise to new possibilities for telling stories. When the context is, for example, to relay information about...
Published by: IGI Global Scientific Publishing
A Go/No-Go Decision-Making Model Based on Risk and Multi-Criteria Techniques for Project Selection
The realization of infrastructures and the deployment of processes can follow project formalism. Generally, a project goes through a design and a realization phase. Between these two phases, there is a crucial milestone...
Published by: IGI Global Scientific Publishing
The management of acute knee dislocations
PURPOSE: Great variety and controversies surround the management strategies of acute multiligament knee injuries (aMKLIs) and no established guidelines exist for resource-limited practices. The aim of this study was to compare...
Does Addictive Pleasure at Work and Building a Personal IS on One's Smartphone Lead to Problematic Smartphone Dependency?
Using a sample of 848 workers in France, this article aims to explain problematic smartphone dependency, a behavior considered to have negative consequences for sufferers in the context of work. It examines whether and how...
Published by: IGI Global Scientific Publishing
The Implications of Schelling’s Metaphysics of Contingency for Phenomenology
Kyla Bruff
Aug 29, 2018
In Ecstasy of Reason, Jean-François Courtine states that F.W.J. Schelling’s late, “positive philosophy” is “not a sublime ground of being as a whole, but the contrary itself of a ground, the attempt of a phenomenology of … the...
Published by: Memorial University Libraries
Computer simulations reveal motor properties generating stable antiparallel microtubule interactions.
François Nédélec
Jul 30, 2020
An aster of microtubules is a set of flexible polar filaments with dynamic plus ends that irradiate from a common location at which the minus ends of the filaments are found. Processive soluble oligomeric motor complexes can...
The Implications of Schelling’s Metaphysics of Contingency for Phenomenology
Kyla Bruff
Aug 29, 2018
In Ecstasy of Reason, Jean-François Courtine states that F.W.J. Schelling’s late, “positive philosophy” is “not a sublime ground of being as a whole, but the contrary itself of a ground, the attempt of a phenomenology of … the...
Published by: Memorial University Libraries
Anthropogenic stressors impact fish sensory development and survival via thyroid disruption.
Marc Besson, William E Feeney, Isadora Moniz, Loïc François, Rohan M Brooker, Guillaume Holzer, Marc Metian, Natacha Roux, Vincent Laudet, David Lecchini
Jul 28, 2021
What Lessons Can Be Learned for the Agroecological Transition From the Use of Social Media in Preventive Medicine?
In agriculture, web-based social media are increasingly used to share knowledge concerning best practices. One goal of agroecology is to reduce the use of synthetic chemical inputs. Agroecology represents a contrast with...
Published by: IGI Global Scientific Publishing
FTT:Power
Jean-François Mercure
Aug 25, 2011
Makerspaces
The emergence of the makerspace movement offers tremendous potential to transform learning. Learning by making, while ancient in practice, has evolved due to the development and confluence of developments in computing...
Educational Technologies Education Educational Technologies Computer Science and Information Technology Media and Communications
Published by: IGI Global Scientific Publishing
Membrane Mechanics of Endocytosis in Cells with Turgor.
Endocytosis is an essential process by which cells internalize a piece of plasma membrane and material from the outside. In cells with turgor, pressure opposes membrane deformations, and increases the amount of force that has to...
Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase
Mark J. Siedner, Michelle A. Moorhouse, Bryony Simmons, Tulio de Oliveira, Richard Lessells, Jennifer Giandhari, Stephen A. Kemp, Benjamin Chimukangara, Godspower Akpomiemie, Celicia M. Serenata, Willem D. F. Venter, Andrew Hill, Ravindra K. Gupta
Dec 02, 2020
Abstract: Little is known about the impact of pretreatment drug resistance (PDR) on the efficacy of second generation integrase inhibitors. We sequenced pretreatment plasma specimens from the ADVANCE trial (NCT03122262). Our...
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
Adjuvants are critical for the success of vaccines. Agonists of microbial pattern recognition receptors (PRRs) are promising new adjuvant candidates. A mechanism through which adjuvants enhance immune responses is to stimulate...
carboxymethylcellulose sod nium Gene Expression Cytokines interferon Signal Transduction virus vaccine
Published by: Rockefeller University
The Cambridge Experiment
Since the latter part of 19th century photography has played a central role in the development of architecture for its persuasive visual impact. But, despite this clear interaction, there is still reluctance from scholars in...
Suffering and Ipseity in Michel Henry
Jean-François Lavigne
Dec 19, 2016
The double expansion that Husserl’s phenomenology imposed on subjectiveexperience posed, among other difficulties, a new and particularly difficultproblem for Husserl; that of the trans-temporal identity of the...
Published by: Memorial University of Newfoundland
Amplification of actin polymerization forces.
The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple...
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