Search
Results: 59
Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells.
John R Ferdinand, Arianne C Richard, Françoise Meylan, Aymen Al-Shamkhani, Richard M Siegel
Jun 22, 2018
Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease.
Arianne C Richard, James E Peters, Natalia Savinykh, James C Lee, Eric T Hawley, Françoise Meylan, Richard M Siegel, Paul A Lyons, Kenneth GC Smith
Sep 05, 2018
Chronic inflammation in inflammatory bowel disease (IBD) results from a breakdown of intestinal immune homeostasis and compromise of the intestinal barrier. Genome-wide association studies have identified over 200 genetic loci...
On the Wiener-Hopf solution of water-wave interaction with a submerged elastic or poroelastic plate.
A solution to the problem of water-wave scattering by a semi-infinite submerged thin elastic plate, which is either porous or non-porous, is presented using the Wiener-Hopf technique. The derivation of the Wiener-Hopf equation...
La Grammaire au Service de la Galanterie? Analyse de Les « Vous » et les « Tu » de Voltaire
Françoise Paulet Dubois
Sep 30, 2014
In his epistle Les "Vous" et les "Tu", Voltaire calls his sweetheart "tu" and"valls" alternately. He could use the familiar address when she was youngand unambitious, but now that she has become a rich and distant lady...
Published by: Atlantic Provinces Linguistic Association
La Grammaire au Service de la Galanterie? Analyse de Les « Vous » et les « Tu » de Voltaire
Françoise Paulet Dubois
Sep 30, 2014
In his epistle Les "Vous" et les "Tu", Voltaire calls his sweetheart "tu" and"valls" alternately. He could use the familiar address when she was youngand unambitious, but now that she has become a rich and distant lady...
Published by: Atlantic Provinces Linguistic Association
Star formation efficiency along the radio jet in Centaurus A
Centaurus A is the most nearby powerful AGN, widely studied at all wavelengths. Molecular gas has been found in the halo at a distance of ~20 kpc from the galaxy centre, associated with HI shells. The molecular gas lies inside...
Performance of early warning signals for disease re-emergence
Developing measures for rapid and early detection of disease re-emergence is important to perform science-based risk assessment of epidemic threats. In the past few years, several early warning signals (EWS) from complex systems...
Star formation efficiency along the radio jet in Centaurus A
Centaurus A is the most nearby powerful AGN, widely studied at all wavelengths. Molecular gas has been found in the halo at a distance of ~20 kpc from the galaxy centre, associated with HI shells. The molecular gas lies inside...
Atomic-to-molecular gas phase transition triggered by the radio jet in Centaurus A
NGC 5128 (Centaurus A) is one of the best example to study AGN-feedback in the local Universe. At 13.5 kpc from the galaxy, optical filaments with recent star formation are lying along the radio-jet direction. We used the...
Atomic-to-molecular gas phase transition triggered by the radio jet in Centaurus A
NGC 5128 (Centaurus A) is one of the best example to study AGN-feedback in the local Universe. At 13.5 kpc from the galaxy, optical filaments with recent star formation are lying along the radio-jet direction. We used the...
Inefficient jet-induced star formation in Centaurus A
Quentin Salomé, Philippe Salomé, Marc-Antoine Miville-Deschênes, Françoise Combes, Stephen Hamer
Dec 01, 2017
NGC 5128 is one of the best targets to study AGN-feedback in the local Universe. At 13.5 kpc from the galaxy, optical filaments with recent star formation lie along the radio-jet direction. It is a testbed region for positive...
Performance of early warning signals for disease re-emergence
Developing measures for rapid and early detection of disease re-emergence is important to perform science-based risk assessment of epidemic threats. In the past few years, several early warning signals (EWS) from complex systems...
Inefficient jet-induced star formation in Centaurus A
Quentin Salomé, Philippe Salomé, Marc-Antoine Miville-Deschênes, Françoise Combes, Stephen Hamer
Dec 01, 2017
NGC 5128 is one of the best targets to study AGN-feedback in the local Universe. At 13.5 kpc from the galaxy, optical filaments with recent star formation lie along the radio-jet direction. It is a testbed region for positive...
Dynamical SPQEIR model assesses the effectiveness of non-pharmaceutical interventions against COVID-19 epidemic outbreaks.
Daniele Proverbio, Françoise Kemp, Stefano Magni, Andreas Husch, Atte Aalto, Laurent Mombaerts, Alexander Skupin, Jorge Gonçalves, Jose Ameijeiras-Alonso, Christophe Ley
Jul 30, 2021
Against the current COVID-19 pandemic, governments worldwide have devised a variety of non-pharmaceutical interventions to mitigate it. However, it is generally difficult to estimate the joint impact of different control...
Modelling COVID-19 dynamics and potential for herd immunity by vaccination in Austria, Luxembourg and Sweden.
Françoise Kemp, Daniele Proverbio, Atte Aalto, Laurent Mombaerts, Aymeric Fouquier d'Hérouël, Andreas Husch, Christophe Ley, Jorge Gonçalves, Alexander Skupin, Stefano Magni
Sep 02, 2021
Against the COVID-19 pandemic, non-pharmaceutical interventions have been widely applied and vaccinations have taken off. The upcoming question is how the interplay between vaccinations and social measures will shape infections...
Model-based assessment of COVID-19 epidemic dynamics by wastewater analysis.
Daniele Proverbio, Françoise Kemp, Stefano Magni, Leslie Ogorzaly, Henry-Michel Cauchie, Jorge Gonçalves, Alexander Skupin, Atte Aalto
Apr 04, 2022
Continuous surveillance of COVID-19 diffusion remains crucial to control its diffusion and to anticipate infection waves. Detecting viral RNA load in wastewater samples has been suggested as an effective approach for epidemic...
Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus.
Matthias Richard, Ana Victoria Gutiérrez, Albertus Viljoen, Daniela Rodriguez-Rincon, Françoise Roquet-Baneres, Mickael Blaise, Isobel Everall, Julian Parkhill, R Andres Floto, Laurent Kremer
May 16, 2019
New therapeutic approaches are needed against Mycobacterium abscessus, a respiratory mycobacterial pathogen that evades efforts to successfully treat infected patients. Clofazimine and bedaquiline, two drugs used for the...
EMSA MmpL Mycobacterium abscessus TetR regulator bedaquiline clofazimine drug resistance mechanisms efflux pumps Antitubercular Agents Clofazimine Diarylquinolines Drug Resistance Multiple Bacterial Genome Bacterial Humans Membrane Transport Proteins Microbial Sensitivity Tests Mycobacterium abscessus Tetracycline Resistance Trans-Activators Tuberculosis Multidrug-Resistant whole genome sequencing
TCR Sequencing Reveals the Distinct Development of Fetal and Adult Human Vγ9Vδ2 T Cells.
Maria Papadopoulou, Paola Tieppo, Naomi McGovern, Françoise Gosselin, Jerry KY Chan, Glenn Goetgeluk, Nicolas Dauby, Alexandra Cogan, Catherine Donner, Florent Ginhoux, Bart Vandekerckhove, David Vermijlen
Oct 28, 2019
Phosphoantigen-reactive Vγ9Vδ2 T cells represent the main innate human γδ T cell subset and dominate the fetal and adult peripheral blood γδ T cell repertoire. It has been hypothesized that adult blood Vγ9Vδ2 T cells find their...
Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice.
Tania Capeloa, Justine A Van de Velde, Donatienne d'Hose, Sara G Lipari, Françoise Derouane, Loïc Hamelin, Marie Bedin, Thibaut Vazeille, François P Duhoux, Michael P Murphy, Paolo E Porporato, Bernard Gallez, Pierre Sonveaux
Nov 16, 2022
At diagnosis, about 35% of pancreatic cancers are at the locally invasive yet premetastatic stage. Surgical resection is not a treatment option, leaving patients with a largely incurable disease that often evolves to the...
MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice.
Tania Capeloa, Joanna Krzystyniak, Amanda Canas Rodriguez, Valéry L Payen, Luca X Zampieri, Erica Pranzini, Françoise Derouane, Thibaut Vazeille, Caroline Bouzin, François P Duhoux, Michael P Murphy, Paolo E Porporato, Pierre Sonveaux
Jun 07, 2022
In oncology, the occurrence of distant metastases often marks the transition from curative to palliative care. Such outcome is highly predictable for breast cancer patients, even if tumors are detected early, and there is no...
MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice.
Tania Capeloa, Joanna Krzystyniak, Amanda Canas Rodriguez, Valéry L Payen, Luca X Zampieri, Erica Pranzini, Françoise Derouane, Thibaut Vazeille, Caroline Bouzin, François P Duhoux, Mike Murphy, Paolo E Porporato, Pierre Sonveaux
Apr 24, 2022
In oncology, the occurrence of distant metastases often marks the transition from curative to palliative care. Such outcome is highly predictable for breast cancer patients, even if tumors are detected early, and there is no...
A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos.
Fabrice Demeter, Clément Zanolli, Kira E Westaway, Renaud Joannes-Boyau, Philippe Duringer, Mike W Morley, Frido Welker, Patrick L Rüther, Matthew M Skinner, Hugh McColl, Charleen Gaunitz, Lasse Vinner, Tyler E Dunn, Jesper V Olsen, Martin Sikora, Jean-Luc Ponche, Eric Suzzoni, Sébastien Frangeul, Quentin Boesch, Pierre-Olivier Antoine, Lei Pan, Song Xing, Jian-Xin Zhao, Richard M Bailey, Souliphane Boualaphane, Phonephanh Sichanthongtip, Daovee Sihanam, Elise Patole-Edoumba, Françoise Aubaile, Françoise Crozier, Nicolas Bourgon, Alexandra Zachwieja, Thonglith Luangkhoth, Viengkeo Souksavatdy, Thongsa Sayavongkhamdy, Enrico Cappellini, Anne-Marie Bacon, Jean-Jacques Hublin, Eske Willerslev, Laura Shackelford
May 18, 2022
The Pleistocene presence of the genus Homo in continental Southeast Asia is primarily evidenced by a sparse stone tool record and rare human remains. Here we report a Middle Pleistocene hominin specimen from Laos, with the...
A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Sylvie Bannwarth, Samira Ait-El-Mkadem, Annabelle Chaussenot, Emmanuelle C Genin, Sandra Lacas-Gervais, Konstantina Fragaki, Laetitia Berg-Alonso, Yusuke Kageyama, Valérie Serre, David G Moore, Annie Verschueren, Cécile Rouzier, Isabelle Le Ber, Gaëlle Augé, Charlotte Cochaud, Françoise Lespinasse, Karine N'Guyen, Anne de Septenville, Alexis Brice, Patrick Yu-Wai-Man, Hiromi Sesaki, Jean Pouget, Véronique Paquis-Flucklinger
Mar 18, 2019
Mitochondrial DNA instability disorders are responsible for a large clinical spectrum, among which amyotrophic lateral sclerosis-like symptoms and frontotemporal dementia are extremely rare. We report a large family with a...
CHCHD10 FTD-ALS mitochondrial DNA instability mitochondrial disorder Age of Onset Aged Alleles Amyotrophic Lateral Sclerosis DNA Mitochondrial Exome Female frontotemporal dementia HeLa Cells Humans Male Middle Aged Mitochondria Mitochondrial Diseases Mitochondrial Proteins Mutation Missense Pedigree Phenotype
Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice.
Tania Capeloa, Justine A Van de Velde, Donatienne d'Hose, Sara G Lipari, Françoise Derouane, Loïc Hamelin, Marie Bedin, Thibaut Vazeille, François P Duhoux, Michael P Murphy, Paolo E Porporato, Bernard Gallez, Pierre Sonveaux
Nov 15, 2022
|
|< |
< |
1 |