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Results: 49
Determining the burden of fungal infections in Zimbabwe.
Zimbabwe currently faces several healthcare challenges, most notably HIV and associated infections including tuberculosis (TB), malaria and recently outbreaks of cholera, typhoid fever and COVID-19. Fungal infections, which are...
Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection.
Anna M Hoy, Rachel J Lundie, Alasdair Ivens, Juan F Quintana, Norman Nausch, Thorsten Forster, Frances Jones, Narcis B Kabatereine, David W Dunne, Francisca Mutapi, Andrew S MacDonald, Amy H Buck
May 20, 2021
BACKGROUND: MicroRNAs (miRNAs) are a class of short non-coding RNA that play important roles in disease processes in animals and are present in a highly stable cell-free form in body fluids. Here, we examine the capacity of host...
Revisiting Musings on Co-Designing Identity-Aware Realities in Virtual Learning
Francisca Yonekura
Jun 14, 2019
Previously, musings on co-designing identity-aware realities in the virtual space focused on the individual self during a learning experience. While preserving the individual self of the learner for a comprehensive outlook, the...
Virtual Learning Environments Education Educational Technologies Computer Science and Information Technology
Published by: IGI Global Scientific Publishing
Musings on Co-designing Identity Aware Realities in Virtual Learning
Francisca Yonekura
Jan 05, 2017
Virtual learning in the third dimension presents many opportunities for meaningful learning to occur. Learning in which the learner's self and the collective self immerse in the co-creation of authentic experiences. The virtues...
Web-Based Teaching & Learning Education Educational Technologies Social Sciences and Humanities Computer Science and Information Technology
Published by: IGI Global Scientific Publishing
Strain rate and temperature dependence of short/unidirectional carbon fibre PEEK hybrid composites
James James Pheysey, Francesco De Cola, Antonio Pellegrino, Francisca Martinez-Hergueta
Jan 01, 2024
Short fibre and hybrid carbon fibre PEEK composite materials were tested in tension and compression under quasi-static and high strain rate conditions to observe the strain rate dependence. Multiple temperatures including room...
Revisiting Musings on Co-Designing Identity-Aware Realities in Virtual Learning
Francisca Yonekura
Dec 19, 2022
Previously, musings on co-designing identity-aware realities in the virtual space focused on the individual self during a learning experience. While preserving the individual self of the learner for a comprehensive outlook, the...
Virtual Communities & Virtual Reality Computer Science and Information Technology Human-Computer Interaction Media and Communications Social Sciences and Humanities
Published by: IGI Global Scientific Publishing
Neural Population Dynamics Underlying Encoding of Time in the Cortico-Striatal Circuit
Francisca Martínez Traub
Jan 01, 0001
Interval timing, the ability to accurately measure elapsed time between events, is critical for generating appropriate behavioral responses. Research conducted over the past decades has implicated the cortico-striatal-thalamic...
Published by: Rockefeller University
Strain rate and temperature dependence of short/unidirectional carbon fibre PEEK hybrid composites
James James Pheysey, Francesco De Cola, Antonio Pellegrino, Francisca Martinez-Hergueta
Jan 01, 2024
Short fibre and hybrid carbon fibre PEEK composite materials were tested in tension and compression under quasi-static and high strain rate conditions to observe the strain rate dependence. Multiple temperatures including room...
Electrophysiological evidence of sustained spatial attention effects over anterior cortex
Marika Berchicci, Antonia Francisca Ten Brink, Federico Quinzi, Rinaldo Livio Perri, Donatella Spinelli, Francesco Di Russo
Jul 01, 2019
Spatial attention can improve performance in terms of speed and accuracy; this advantage may be mediated by brain processes at both poststimulus (reactive) and prestimulus (proactive) stages. Here, we studied how visuospatial...
Electrophysiological evidence of sustained spatial attention effects over anterior cortex
Marika Berchicci, Antonia Francisca Ten Brink, Federico Quinzi, Rinaldo Livio Perri, Donatella Spinelli, Francesco Di Russo
Jul 01, 2019
Spatial attention can improve performance in terms of speed and accuracy; this advantage may be mediated by brain processes at both poststimulus (reactive) and prestimulus (proactive) stages. Here, we studied how visuospatial...
Accurate Dust Temperature and Star Formation Rate in the Most Luminous z > 6 Quasar in the Hyperluminous Quasars at the Epoch of Reionization (HYPERION) Sample
Roberta Tripodi, Chiara Feruglio, Francisca Kemper, Francesca Civano, Tiago Costa, Martin Elvis, Manuela Bischetti, Stefano Carniani, Fabio Di Mascia, Valentina D’Odorico, Fabrizio Fiore, Simona Gallerani, Michele Ginolfi, Roberto Maiolino, Enrico Piconcelli, Rosa Valiante, Luca Zappacosta
Apr 05, 2023
Proactive breast cancer risk assessment in primary care
Personalised Risk Prediction in Hereditary Breast and Ovarian Cancer
Stephanie Archer, Nichola Fennell, Ellen Colvin, Rozelle Laquindanum, Meredith Mills, Romy Dennis, Francisca Stutzin Donoso, Rochelle Gold, Alice Fan, Kate Downes, James Ford, Antonis C Antoniou, Allison W Kurian, D Gareth Evans, Marc Tischkowitz
Jul 10, 2022
Women who test positive for an inherited pathogenic/likely pathogenic gene variant in BRCA1, BRCA2, PALB2, CHEK2 and ATM are at an increased risk of developing certain types of cancer-specifically breast (all) and epithelial...
The message on the bottle
Stephen D. Burrows, Francisca Ribeiro, Stacey O'Brien, Elvis Okoffo, Tania Toapanta, Nathan Charlton, Sarit Kaserzon, Chun Yin Lin, Cheng Tang, Cassandra Rauert, Xianyu Wang, Katja Shimko, Jake O'Brien, Piers A. Townsend, Matthew N. Grayson, Tamara Galloway, Kevin V. Thomas
Jun 01, 2022
Plastic pollution continues to worsen globally in volume and complexity. The complexity in plastic production, use and disposal is significant, highlighting the importance of clear communication to consumers. Yet despite...
ERIC-PCR Analysis of the Clinical and Environmental strains of V. cholerae during 2013 Epidemic in Nigeria
Smith Stella, Nwaokorie Francisca, Awoderu Oluwatoyin, Bamidele Tajudeen, Akinsinde Kehinde, Ochoga Michael, Oladele David, Bamidele Moses, Fesobi Toun, Afocha Eberechukwu, Amoo Samuel, Ajayi Morakinyo, Atat Prince, Ogbonna Francisca, Nduaga Samuel, Idika Nneoma, Oparaugo Chinedu, Musa Adesola, Adeneye Adeniyi, Ijeh Margaret, Ujah Innocent
Nov 21, 2015
Background: Molecular markers are important tools in the monitoring of toxigenic strains of Vibrio cholerae in environmental and clinical samples.
Objectives: The study was aimed at determining the clinical and environmental...
Published by: IJHS Medical Association
Legal and ethical framework for global health information and biospecimen exchange - an international perspective.
Lara Bernasconi, Selçuk Şen, Luca Angerame, Apolo P Balyegisawa, Damien Hong Yew Hui, Maximilian Hotter, Chung Y Hsu, Tatsuya Ito, Francisca Jörger, Wolfgang Krassnitzer, Adam T Phillips, Rui Li, Louise Stockley, Fabian Tay, Charlotte von Heijne Widlund, Ming Wan, Creany Wong, Henry Yau, Thomas F Hiemstra, Yagiz Uresin, Gabriela Senti
Jan 20, 2021
BACKGROUND: The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to...
ERIC-PCR Analysis of the Clinical and Environmental strains of V. cholerae during 2013 Epidemic in Nigeria
Smith Stella, Nwaokorie Francisca, Awoderu Oluwatoyin, Bamidele Tajudeen, Akinsinde Kehinde, Ochoga Michael, Oladele David, Bamidele Moses, Fesobi Toun, Afocha Eberechukwu, Amoo Samuel, Ajayi Morakinyo, Atat Prince, Ogbonna Francisca, Nduaga Samuel, Idika Nneoma, Oparaugo Chinedu, Musa Adesola, Adeneye Adeniyi, Ijeh Margaret, Ujah Innocent
Nov 21, 2015
Background: Molecular markers are important tools in the monitoring of toxigenic strains of Vibrio cholerae in environmental and clinical samples.
Objectives: The study was aimed at determining the clinical and environmental...
Published by: IJHS Medical Association
A versatile drug delivery system targeting senescent cells.
Daniel Muñoz-Espín, Miguel Rovira, Irene Galiana, Cristina Giménez, Beatriz Lozano-Torres, Marta Paez-Ribes, Susana Llanos, Selim Chaib, Maribel Muñoz-Martín, Alvaro C Ucero, Guillermo Garaulet, Francisca Mulero, Stephen G Dann, Todd VanArsdale, David J Shields, Andrea Bernardos, José Ramón Murguía, Ramón Martínez-Máñez, Manuel Serrano
Sep 20, 2018
Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β-galactosidase activity of...
Chemotherapy Fibrosis nanomedicine palbociclib Senescence Animals Cell Survival Cellular Senescence Cytotoxins Disease Models Animal Drug Compounding Drug Delivery Systems Fluorescent Dyes Galactose Heterografts Lysosomes Mice Neoplasm Transplantation Neoplasms Oligosaccharides Piperazines Pyridines Staining and Labeling beta-Galactosidase
Legal and ethical framework for global health information and biospecimen exchange - an international perspective
Lara Bernasconi, Selçuk Şen, Luca Angerame, Apolo P. Balyegisawa, Damien Hong Yew Hui, Maximilian Hotter, Chung Y. Hsu, Tatsuya Ito, Francisca Jörger, Wolfgang Krassnitzer, Adam T. Phillips, Rui Li, Louise Stockley, Fabian Tay, Charlotte von Heijne Widlund, Ming Wan, Creany Wong, Henry Yau, Thomas F. Hiemstra, Yagiz Uresin, Gabriela Senti
Jun 06, 2020
Abstract: Background: The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential...
The message on the bottle
Stephen D. Burrows, Francisca Ribeiro, Stacey O'Brien, Elvis Okoffo, Tania Toapanta, Nathan Charlton, Sarit Kaserzon, Chun Yin Lin, Cheng Tang, Cassandra Rauert, Xianyu Wang, Katja Shimko, Jake O'Brien, Piers A. Townsend, Matthew N. Grayson, Tamara Galloway, Kevin V. Thomas
Jun 01, 2022
Plastic pollution continues to worsen globally in volume and complexity. The complexity in plastic production, use and disposal is significant, highlighting the importance of clear communication to consumers. Yet despite...
Legal and ethical framework for global health information and biospecimen exchange - an international perspective.
Lara Bernasconi, Selçuk Şen, Luca Angerame, Apolo P Balyegisawa, Damien Hong Yew Hui, Maximilian Hotter, Chung Y Hsu, Tatsuya Ito, Francisca Jörger, Wolfgang Krassnitzer, Adam T Phillips, Rui Li, Louise Stockley, Fabian Tay, Charlotte von Heijne Widlund, Ming Wan, Creany Wong, Henry Yau, Thomas F Hiemstra, Yagiz Uresin, Gabriela Senti
Feb 22, 2020
BACKGROUND:The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to...
Published by: BMC medical ethics
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.
Joshua M Dempster, Clare Pacini, Sasha Pantel, Fiona M Behan, Thomas Green, John Krill-Burger, Charlotte M Beaver, Scott T Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G Doench, Kosuke Yusa, Francisca Vazquez, Leopold Parts, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Feb 24, 2020
Genome-scale CRISPR-Cas9 viability screens performed in cancer cell lines provide a systematic approach to identify cancer dependencies and new therapeutic targets. As multiple large-scale screens become available, a formal...
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Lourdes Ortiz-Fernández, Francisco David Carmona, Raquel López-Mejías, Maria Francisca González-Escribano, Paul A Lyons, Ann W Morgan, Amr H Sawalha, Peter A Merkel, Kenneth GC Smith, Miguel A González-Gay, Javier Martín, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group Spanish GCA Study Group
Apr 18, 2018
OBJETIVE: Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we...
Autoantibodies outcomes research systemic sclerosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Case-Control Studies Epigenesis Genetic Female Genetic Loci Genetic Predisposition to Disease Giant Cell Arteritis HLA-DQ Antigens HLA-DQ beta-Chains Humans Jumonji Domain-Containing Histone Demethylases Linkage Disequilibrium Male Phenotype Polymorphism Single Nucleotide Protein Array Analysis Systemic Vasculitis Takayasu arteritis
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
David T Burns, Sandra Donkervoort, Juliane S Müller, Ellen Knierim, Diana Bharucha-Goebel, Eissa Ali Faqeih, Stephanie K Bell, Abdullah Y AlFaifi, Dorota Monies, Francisca Millan, Kyle Retterer, Sarah Dyack, Sara MacKay, Susanne Morales-Gonzalez, Michele Giunta, Benjamin Munro, Gavin Hudson, Mena Scavina, Laura Baker, Tara C Massini, Monkol Lek, Ying Hu, Daniel Ezzo, Fowzan S Alkuraya, Peter B Kang, Helen Griffin, A Reghan Foley, Markus Schuelke, Rita Horvath, Carsten G Bönnemann
Mar 07, 2019
The exosome is a conserved multi-protein complex that is essential for correct RNA processing. Recessive variants in exosome components EXOSC3, EXOSC8, and RBM7 cause various constellations of pontocerebellar hypoplasia (PCH)...
RNA metabolism cerebellar atrophy Exosome Neurodegenerative Diseases Spinal Muscular Atrophy Amino Acid Sequence Animals Atrophy Base Sequence cerebellum Child Preschool Exosome Multienzyme Ribonuclease Complex Exosomes Female FIBROBLASTS Gene Knockdown Techniques genetic variation Haplotypes Humans Infant Male Motor Neurons Muscle Skeletal Pedigree RNA-Binding Proteins Spinal Cord Zebrafish
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