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The Public Sector Cloud Service Procurement in Sweden
This paper investigates the use of cloud services in the public sector and management of information security challenges in the procurement of such services. The findings are based on an exploratory approach that included a...
Published by: IGI Global Scientific Publishing
High-throughput total RNA sequencing in single cells using VASA-seq.
Fredrik Salmen, Joachim De Jonghe, Tomasz S Kaminski, Anna Alemany, Guillermo E Parada, Joe Verity-Legg, Ayaka Yanagida, Timo N Kohler, Nicholas Battich, Floris van den Brekel, Anna L Ellermann, Alfonso Martinez Arias, Jennifer Nichols, Martin Hemberg, Florian Hollfelder, Alexander van Oudenaarden
Dec 15, 2022
Most methods for single-cell transcriptome sequencing amplify the termini of polyadenylated transcripts, capturing only a small fraction of the total cellular transcriptome. This precludes the detection of many long non-coding...
Competing models of organizational form
Mutual and stock insurers have coexisted and competed against each other in insurance markets for centuries. In this article, we examine the risk management strategies and underwriting profitability of the different...
Accuracy in local staging of prostate cancer by adding a three-dimensional T2-weighted sequence with radial reconstructions in magnetic resonance imaging.
Fredrik Jäderling, Tommy Nyberg, Michael Öberg, Stefan Carlsson, Mikael Skorpil, Lennart Blomqvist
Jun 08, 2018
BACKGROUND: The evidence supporting the use of magnetic resonance imaging (MRI) in prostate cancer detection has been established, but its accuracy in local staging is questioned. PURPOSE: To investigate the additional value of...
A millennium-long reconstruction of damaging hydrological events across Italy
Abstract: Damaging hydrological events are extreme phenomena with potentially severe impacts on human societies. Here, we present the hitherto longest reconstruction of damaging hydrological events for Italy, and for the whole...
Computational Chemistry on a Budget
An increasing number of new drugs have their origin in small biotech or academia. In contrast to big pharma, these environments are often more limited in terms of resources, and this necessitates different approaches to the drug...
A millennium-long reconstruction of damaging hydrological events across Italy.
Damaging hydrological events are extreme phenomena with potentially severe impacts on human societies. Here, we present the hitherto longest reconstruction of damaging hydrological events for Italy, and for the whole...
Fragment-Based Drug Discovery of Phosphodiesterase Inhibitors.
Phosphodiesterases are proving to be fruitful targets for drug discovery. At the same time fragment-based drug discovery has matured into a powerful and widely applied technique. In this communication we review the application...
Firm size and growth in Sweden's life insurance market between 1855 and 1947
Using data for the period from 1855 to 1947 and the two sub-periods, 1855-1902 and 1903-47, the article examines whether the organic growth rates of 38 Swedish life insurance firms are independent of size, as predicted by...
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's...
Competing models of organizational form
Mutual and stock insurers have coexisted and competed against each other in insurance markets for centuries. In this article, we examine the risk management strategies and underwriting profitability of the different...
Firm size and growth in Sweden's life insurance market between 1855 and 1947
Using data for the period from 1855 to 1947 and the two sub-periods, 1855-1902 and 1903-47, the article examines whether the organic growth rates of 38 Swedish life insurance firms are independent of size, as predicted by...
Exchange Bias in Magnetic Topological Insulator Superlattices.
Jieyi Liu, Angadjit Singh, Yu Yang Fredrik Liu, Adrian Ionescu, Balati Kuerbanjiang, Crispin HW Barnes, Thorsten Hesjedal
Sep 27, 2021
Magnetic doping and proximity coupling can open a band gap in a topological insulator (TI) and give rise to dissipationless quantum conduction phenomena. Here, by combining these two approaches, we demonstrate a novel TI...
Managing policy lapse risk in Sweden's life insurance market between 1915 and 1947
Michael Adams, Lars Fredrik Andersson, Liselotte Eriksson, Magnus Lindmark, Elena Veprauskaite
Feb 17, 2020
We examine the challenges that Swedish life insurers faced in managing the lapse risk of policies written on the lives of the industrial urban working-class between 1915 and 1947. We observe that with the threat of State...
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient’s...
Managing policy lapse risk in Sweden's life insurance market between 1915 and 1947
Michael Adams, Lars Fredrik Andersson, Liselotte Eriksson, Magnus Lindmark, Elena Veprauskaite
Feb 17, 2020
We examine the challenges that Swedish life insurers faced in managing the lapse risk of policies written on the lives of the industrial urban working-class between 1915 and 1947. We observe that with the threat of State...
Association between blood pressure and BMI with bladder cancer risk and mortality in 340,000 men in three Swedish cohorts.
Stanley Teleka, Sylvia HJ Jochems, Christel Häggström, Angela M Wood, Bengt Järvholm, Marju Orho-Melander, Fredrik Liedberg, Tanja Stocks
Mar 09, 2021
BACKGROUND: The relation between obesity, blood pressure (BP) and bladder cancer (BC) risk and mortality remains unclear, partially due to potential confounding by smoking, the strongest risk factor for BC, and not accounting...
Probabilistic identification of cerebellar cortical neurones across species.
Gert Van Dijck, Marc M Van Hulle, Shane A Heiney, Pablo M Blazquez, Hui Meng, Dora E Angelaki, Alexander Arenz, Troy W Margrie, Abteen Mostofi, Steve Edgley, Fredrik Bengtsson, Carl-Fredrik Ekerot, Henrik Jörntell, Jeffrey W Dalley, Tahl Holtzman
Jan 11, 2021
Despite our fine-grain anatomical knowledge of the cerebellar cortex, electrophysiological studies of circuit information processing over the last fifty years have been hampered by the difficulty of reliably assigning signals to...
Systematic Analysis of Protein Targets Associated with Adverse Events of Drugs from Clinical Trials and Postmarketing Reports.
Ines A Smit, Avid M Afzal, Chad HG Allen, Fredrik Svensson, Thierry Hanser, Andreas Bender
Jan 14, 2021
Adverse drug reactions (ADRs) are undesired effects of medicines that can harm patients and are a significant source of attrition in drug development. ADRs are anticipated by routinely screening drugs against secondary...
Microbial regulation of the L cell transcriptome.
Tulika Arora, Rozita Akrami, Ramona Pais, Linda Bergqvist, Bengt R Johansson, Thue W Schwartz, Frank Reimann, Fiona M Gribble, Fredrik Bäckhed
Apr 26, 2018
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
Wood Formation Modeling - A Research Review and Future Perspectives.
Annemarie H Eckes-Shephard, Fredrik Charpentier Ljungqvist, David M Drew, Cyrille BK Rathgeber, Andrew D Friend
Apr 06, 2022
Wood formation has received considerable attention across various research fields as a key process to model. Historical and contemporary models of wood formation from various disciplines have encapsulated hypotheses such as the...
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