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Results: 133
GH safety workshop position paper
DB Allen, P Backeljauw, M Bidlingmaier, BMK Biller, M Boguszewski, P Burman, G Butler, K Chihara, J Christiansen, S Cianfarani, P Clayton, D Clemmons, P Cohen, F Darendeliler, C Deal, D Dunger, EM Erfurth, JS Fuqua, A Grimberg, M Haymond, C Higham, K Ho, AR Hoffman, A Hokken-Koelega, G Johannsson, A Juul, J Kopchick, P Lee, M Pollak, S Radovick, L Robison, R Rosenfeld, RJ Ross, L Savendahl, P Saenger, HT Sorensen, K Stochholm, C Strasburger, A Swerdlow, M Thorner
Dec 08, 2017
Recombinant human GH (rhGH) has been in use for 30 years, and over that time its safety and efficacy in children and adults has been subject to considerable scrutiny. In 2001, a statement from the GH Research Society (GRS)...
Optimizing Patient Management and Adherence for Children Receiving Growth Hormone.
Poor adherence with growth hormone (GH) therapy has been associated with worse clinical outcomes, which in children relates specifically to their linear growth and loss of quality of life. The "360° GH in Europe" meeting, held...
Time for a general approval of growth hormone treatment in adults with Prader-Willi syndrome.
Charlotte Höybye, Anthony J Holland, Daniel J Driscoll, Clinical and Scientific Advisory Board of The International Prader-Willi Syndrome Organisation
Feb 15, 2021
Prader-Willi syndrome (PWS) is a complex, multi-system, neurodevelopmental disorder characterised by neonatal muscular hypotonia, short stature, high risk of obesity, hypogonadism, intellectual disabilities, distinct...
Diagnosis of bladder cancer by immunocytochemical detection of minichromosome maintenance protein-2 in cells retrieved from urine.
K Saeb-Parsy, A Wilson, C Scarpini, M Corcoran, S Chilcott, M McKean, B Thottakam, B Rai, G Nabi, D Rana, M Perera, K Stewart, RA Laskey, DE Neal, N Coleman
Aug 19, 2020
BACKGROUND: We tested the accuracy of immunocytochemistry (ICC) for minichromosome maintenance protein-2 (MCM-2) in diagnosing bladder cancer, using cells retrieved from urine. METHODS: Adequate samples were obtained from 497...
Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA.
Mathilde Gersel Wegmann, Rikke Beck Jensen, Ajay Thankamony, Jan Frystyk, Edna Roche, Hilary Hoey, Jeremy Kirk, Guftar Shaikh, Sten-A Ivarsson, Olle Söder, David B Dunger, Anders Juul
Nov 19, 2019
BACKGROUND: Some children born small for gestational age (SGA) experience supra-physiological insulin-like growth factor-I (IGF-I) concentrations during GH treatment. However, measurements of total IGF-I concentrations may not...
Characterisation of myocardial structure and function in adult-onset growth hormone deficiency using cardiac magnetic resonance.
Julia DJ Thomas, Abhishek Dattani, Filip Zemrak, Thomas Burchell, Scott A Akker, Mark Gurnell, Ashley B Grossman, L Ceri Davies, Márta Korbonits
Nov 13, 2018
Growth hormone (GH) can profoundly influence cardiac function. While GH excess causes well-defined cardiac pathology, fewer data are available regarding the more subtle cardiac changes seen in GH deficiency (GHD). This...
Farmers’ perceptions of the effectiveness of the Cocoa Disease and Pest Control Programme (CODEPEC) in Ghana and its effects on poverty reduction
The study examined the contribution of the Cocoa Disease and Pest Control Programme (CODAPEC), which is a cocoa production-enhancing government policy, to reducing poverty and raising the living standards of cocoa farmers in...
Point process simulation of generalised inverse Gaussian processes and estimation of the Jaeger integral
In this paper novel simulation methods are provided for the generalised inverse Gaussian (GIG) L\'{e}vy process. Such processes are intractable for simulation except in certain special edge cases, since the L\'{e}vy density...
Farmers’ perceptions of the effectiveness of the Cocoa Disease and Pest Control Programme (CODEPEC) in Ghana and its effects on poverty reduction
The study examined the contribution of the Cocoa Disease and Pest Control Programme (CODAPEC), which is a cocoa production-enhancing government policy, to reducing poverty and raising the living standards of cocoa farmers in...
Piezoelectric Performance and Hydrostatic Parameters of Novel 2–2-Type Composites
This paper provides a detailed study of the structure - piezoelectric property relationships and the hydrostatic response of 2–2-type composites based on relaxor-ferroelectric...
acoustics crystals dielectrics Electronic Mail Ferroelectric Materials Ferroelectric Properties frequency control Indexes Piezoelectric and Ferroelectric Transducer Materials Polymers /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation /dk/atira/pure/subjectarea/asjc/3100/3102 name=Acoustics and Ultrasonics /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Piezoelectric Performance and Hydrostatic Parameters of Novel 2–2-Type Composites
This paper provides a detailed study of the structure - piezoelectric property relationships and the hydrostatic response of 2–2-type composites based on relaxor-ferroelectric...
acoustics crystals dielectrics Electronic Mail Ferroelectric Materials Ferroelectric Properties frequency control Indexes Piezoelectric and Ferroelectric Transducer Materials Polymers /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation /dk/atira/pure/subjectarea/asjc/3100/3102 name=Acoustics and Ultrasonics /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
New orientation effect in piezo-active 1-3-type composites
This paper demonstrates the influence of the mutual orientation of the poling direction of single-crystal and ceramic components on the properties of 1-0-3 composites containing two ferroelectric components and a...
A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Alan Cartmell, Jose Muñoz-Muñoz, Jonathon A Briggs, Didier A Ndeh, Elisabeth C Lowe, Arnaud Baslé, Nicolas Terrapon, Katherine Stott, Tiaan Heunis, Joe Gray, Li Yu, Paul Dupree, Pearl Z Fernandes, Sayali Shah, Spencer J Williams, Aurore Labourel, Matthias Trost, Bernard Henrissat, Harry J Gilbert
Apr 03, 2019
Glycans are major nutrients for the human gut microbiota (HGM). Arabinogalactan proteins (AGPs) comprise a heterogenous group of plant glycans in which a β1,3-galactan backbone and β1,6-galactan side chains are conserved....
High piezoelectric sensitivity and hydrostatic figures of merit in unidirectional porous ferroelectric ceramics fabricated by freeze casting
High performance lead zirconate titanate (PZT) ceramics with aligned porosity for sensing applications were fabricated by an ice-templating method. To demonstrate the enhanced properties of these materials and their potential...
New orientation effect in piezo-active 1-3-type composites
This paper demonstrates the influence of the mutual orientation of the poling direction of single-crystal and ceramic components on the properties of 1-0-3 composites containing two ferroelectric components and a...
High piezoelectric sensitivity and hydrostatic figures of merit in unidirectional porous ferroelectric ceramics fabricated by freeze casting
High performance lead zirconate titanate (PZT) ceramics with aligned porosity for sensing applications were fabricated by an ice-templating method. To demonstrate the enhanced properties of these materials and their potential...
Point process simulation of generalised inverse Gaussian processes and estimation of the Jaeger integral
Abstract In this paper novel simulation methods are provided for the generalised inverse Gaussian (GIG) Lévy process. Such processes are intractable for simulation except in certain special edge...
SONS
WS Holland, BC Matthews, GM Kennedy, JS Greaves, MC Wyatt, M Booth, P Bastien, G Bryden, H Butner, CH Chen, A Chrysostomou, CL Davies, WRF Dent, J Di Francesco, G Duchene, AG Gibb, P Friberg, RJ Ivison, T Jenness, J Kavelaars, S Lawler, J-F Lestrade, JP Marshall, A Moro-Martin, O Panic, N Phillips, S Serjeant, GH Schieven, B Sibthorpe, L Vican, D Ward-Thompson, P Van Der Werf, GJ White, D Wilner, B Zuckerman
Sep 15, 2017
Acromegaly and Cushing's syndrome caused by a neuroendocrine tumor arising within a sacrococcygeal teratoma.
Tarig Babiker, Efstathia Kyrodimou, Daniel M Berney, Mark Gurnell, William M Drake, Antonia Brooke
Nov 13, 2018
A 60-year-old man with a pre-existing stable sacrococcygeal teratoma developed acromegaly, ectopic Cushing's syndrome, and 5HIAA secretion. To our knowledge, this represents the first reported case of ACTH and serotonin...
Change in cardio-protective medication and health-related quality of life after diagnosis of screen-detected diabetes
Diabetes HRQoL Medication Adult Aged Cardiotonic Agents Cardiovascular Diseases Cohort Studies Diabetes mellitus Type 2 Diabetic Angiopathies Drug Prescriptions Female health status Humans Male Mass Screening Mental Health Middle Aged Practice Patterns Physicians' Quality of life Surveys and Questionnaires United Kingdom
Secular Trends on Birth Parameters, Growth, and Pubertal Timing in Girls with Turner Syndrome.
Joachim Woelfle, Anders Lindberg, Ferah Aydin, Ken K Ong, Cecilia Camacho-Hubner, Bettina Gohlke
Apr 19, 2018
BACKGROUND: Whether children with chromosomal disorders of growth and puberty are affected by secular trends (STs) as observed in the general population remains unanswered, but this question has relevance for expectations of...
Combinatorial Conflicting Homozygosity (CCH) analysis enables the rapid identification of shared genomic regions in the presence of multiple phenocopies.
The ability to identify regions of the genome inherited with a dominant trait in one or more families has become increasingly valuable with the wide availability of high throughput sequencing technology. While a number of...
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