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Results: 699
Neutrophil GM-CSF receptor dynamics in acute lung injury.
Silvia De Alessandris, G John Ferguson, Alison J Dodd, Jatinder K Juss, Abhinandan Devaprasad, Siân Piper, Owen Wyatt, Helen Killick, Dominic J Corkill, E Suzanne Cohen, Aridaman Pandit, Timothy RDJ Radstake, Rosalind Simmonds, Alison M Condliffe, Matthew A Sleeman, Andrew S Cowburn, Donna K Finch, Edwin R Chilvers
May 07, 2019
GM-CSF is important in regulating acute, persistent neutrophilic inflammation in certain settings, including lung injury. Ligand binding induces rapid internalization of the GM-CSF receptor (GM-CSFRα) complex, a process...
LPS Alveolar Apoptosis Inflammation signaling Acute Lung Injury Adult Animals Cell Line Tumor Cytokine Receptor Common beta Subunit Disease Models Animal Female Gene Expression Regulation Humans Lipopolysaccharides Male Mice Mice Inbred BALB C Mice Transgenic Neutrophils Pulmonary Alveoli Receptors Granulocyte-Macrophage Colony-Stimulating Factor Time Factors
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Tomas Castro-Dopico, Aaron Fleming, Thomas W Dennison, John R Ferdinand, Katherine Harcourt, Benjamin J Stewart, Zaeem Cader, Zewen K Tuong, Chenzhi Jing, Laurence SC Lok, Rebeccah J Mathews, Anaïs Portet, Arthur Kaser, Simon Clare, Menna R Clatworthy
Jun 16, 2020
Macrophages play a central role in intestinal immunity, but inappropriate macrophage activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-macrophage colony stimulating factor (GM-CSF) as...
GM-CSF anti-microbial defense Crosstalk inflammatory bowel disease innate lymphoid cells MACROPHAGES Wound Healing Animals Cell Polarity Citrobacter rodentium Colitis Enterobacteriaceae Infections Granulocyte-Macrophage Colony-Stimulating Factor Humans Immunity Innate Inflammation Intestines Lymphocytes Macrophage Activation MACROPHAGES Mice Inbred C57BL Phenotype Wound Healing
The Grizzly, September 20, 2007
Matt Flyntz, Lane Taylor, Caitlin Dalik, Ashley McComeskey, Ashley Higgins, Salia Zouande, Zach Shamberg, Zakary Arnhold, Daniel Sergeant, Laurel Salvo, Alex Ernst, Jason Davis, Ashley Drogalis, Daniel Price
Jan 01, 0001
Berman Unveils Fiber Art Exhibit by Peri Organs Sound for Recital Kickoff "Ashley Treatment" Sparks Debate SAO Reveals New Events for Fall Popping the Pill Scudera's Gilgamesh UC Unplugged Fringe Festivities Begin This...
Ursinus College Collegeville Pennsylvania newspaper Eve Peri Berman Art Museum Alan Morrison Student Activities Office Domenick Scudera CIE energy conservation fringe festival field hockey Football cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Ashley Ridge High School Takes Top Honors at Model UN
Winthrop University
Jan 01, 0001
Quick Facts
Held March 21-23, the Model UN program involved hundreds of students representing nearly 30 Carolina high schools. The overall award -- the Winthrop Cup -- went to Ashley Ridge High students who represented Egypt...
Published by: Winthrop University
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.
Jan Felix, Eaazhisai Kandiah, Steven De Munck, Yehudi Bloch, Gydo CP van Zundert, Kris Pauwels, Ann Dansercoer, Katka Novanska, Randy J Read, Alexandre MJJ Bonvin, Bjorn Vergauwen, Kenneth Verstraete, Irina Gutsche, Savvas N Savvides
Jul 06, 2020
Subversion of the host immune system by viruses is often mediated by molecular decoys that sequester host proteins pivotal to mounting effective immune responses. The widespread mammalian pathogen parapox Orf virus deploys GIF...
Bandwidth Estimation and Optimized Bitrate Selection for Dynamic Adaptive Streaming Over HTTP Using RSI-GM and ISSO
Dynamic Adaptive Streaming over HTTP (DASH) is an emerging solution that aims to standardize existing proprietary streaming systems. DASH specification defines the media presentation description (MPD), which describes a list of...
Computer Vision & Image Processing Computer Science and Information Technology Computer Vision and Machine Perception
Published by: IGI Global Scientific Publishing
A randomised trial of anti-GM-CSF otilimab in severe COVID-19 pneumonia (OSCAR).
Jatin Patel, Damon Bass, Albertus Beishuizen, Xavier Bocca Ruiz, Hatem Boughanmi, Anthony Cahn, Hugo Colombo, Gerard J Criner, Katherine Davy, Javier de-Miguel-Díez, Pablo A Doreski, Sofia Fernandes, Bruno François, Anubha Gupta, Kate Hanrott, Timothy Hatlen, Dave Inman, John D Isaacs, Emily Jarvis, Natalia Kostina, Tatiana Kropotina, Jean-Claude Lacherade, Divya Lakshminarayanan, Pedro Martinez-Ayala, Charlene McEvoy, Ferhat Meziani, Mehran Monchi, Sumanta Mukherjee, Rosana Muñoz-Bermúdez, Jessica Neisen, Ciara O'Shea, Gaëtan Plantefeve, Lorrie Schifano, Lee E Schwab, Zainab Shahid, Michinori Shirano, Julia E Smith, Eduardo Sprinz, Charlotte Summers, Nicolas Terzi, Mark A Tidswell, Yuliya Trefilova, Russell Williamson, Duncan Wyncoll, Mark Layton
Nov 16, 2022
BACKGROUND: Granulocyte-macrophage colony-stimulating factor (GM-CSF) and dysregulated myeloid cell responses are implicated in the pathophysiology and severity of COVID-19. METHODS: In this randomised, sequential, multicentre...
Welcome Week Activities Includes Entertainment for New Students
Winthrop University
Jan 01, 0001
The entertainment portion of Welcome Week will be coordinated by the Dinkins Student Union Programming Board. The new DSU president is Ashley Camille Hunter and vice president is Lindsay Sherria Johnson.
Published by: Winthrop University
Student Life Recognizes Achievements by Students, Greek Life, Clubs and Staff
Winthrop University
Jan 01, 0001
Ashley Causey took the Mary Mildred Sullivan Award, while Victor Volious won the Algernon Sydney Sullivan Award. The prestigious American Legion Awards were given to Akeria "Keri" Massey-Shands of Spartanburg, South Carolina...
Published by: Winthrop University
Higher midlife CAIDE score is associated with increased brain atrophy in a cohort of cognitively healthy middle-aged individuals
Xulin Liu, Maria-Eleni Dounavi, Karen Ritchie, Katie Wells, Craig W. Ritchie, Li Su, Graciela Muniz-Terrera, John T. O’Brien
Apr 24, 2021
Abstract: Background: Structural brain changes associated with Alzheimer’s disease (AD) can occur decades before the onset of symptoms. The Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) score has been suggested to be...
Higher midlife CAIDE score is associated with increased brain atrophy in a cohort of cognitively healthy middle-aged individuals.
Xulin Liu, Maria-Eleni Dounavi, Karen Ritchie, Katie Wells, Craig W Ritchie, Li Su, Graciela Muniz-Terrera, John T O'Brien
Dec 23, 2020
BACKGROUND: Structural brain changes associated with Alzheimer's disease (AD) can occur decades before the onset of symptoms. The Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) score has been suggested to be associated...
New Gift Establishes Social Work Scholarship at Winthrop
Winthrop University
Jan 01, 0001
The Linda M. Ashley Endowed Scholarship for Social Work will support non-traditional students seeking undergraduate or graduate degrees in social work.
Published by: Winthrop University
Design Students Match Up Against Peers in State Competition
Winthrop University
Jan 01, 0001
Faculty member Jesse Weser submitted to a professional design organization show class projects by student Ashley Cook of Greenwood, South Carolina, Savannah Ray of Rock Hill and Wesley Fry of Greenville, South Carolina. The...
Published by: Winthrop University
The Ursinus Weekly, October 8, 1970
Alan Gold, Bob Swarr, Candy Silver, Marc Hauser, Charles Chambers, Cris Crane, Peter von Sothen
Jan 01, 0001
Pettit inauguration scheduled; Appointments still undetermined Ursinus institutes security measures to protect students Obituaries: Dr. Paul R. Wagner; Nora Shuler Helfferich Ashley Montagu appears in first Forum program ...
Ursinus College Collegeville Pennsylvania newspaper William Schuyler Pettit Donald L. Helfferich security Miley Detective Agency identification cards Paul R. Wagner Nora Shuler Helfferich Ashley Montagu Art Severance field hockey Football cross country Bruce Albert cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils.
Andrew S Cowburn, Charlotte Summers, Benjamin J Dunmore, Neda Farahi, Richard P Hayhoe, Cristin G Print, Simon J Cook, Edwin R Chilvers
Jun 19, 2018
Neutrophil apoptosis is essential for the resolution of inflammation but is delayed by several inflammatory mediators. In such terminally differentiated cells it has been uncertain whether these agents can inhibit apoptosis...
Apoptosis Apoptosis Regulatory Proteins Bcl-2-Like Protein 11 Caspase 9 Cell Survival Gene Expression Regulation Granulocyte Colony-Stimulating Factor Granulocyte-Macrophage Colony-Stimulating Factor Humans Inflammation Membrane Proteins Microscopy Confocal Models Biological Neutrophils Phenotype Pneumonia Proto-Oncogene Proteins Tumor Necrosis Factor-alpha
Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation
Puja Mehta, Joanna C Porter, Jessica J Manson, John D Isaacs, Peter JM Openshaw, Iain B McInnes, Charlotte Summers, Rachel C Chambers
Jun 11, 2020
The COVID-19 pandemic is a global public health crisis, with considerable mortality and morbidity exerting pressure on health-care resources, including critical care. An excessive host inflammatory response in a subgroup of...
China Internship Teaches New Grads Relationship-Building, Classroom Confidence
Winthrop University
Jan 01, 0001
Ashley Crossland is a special education major from West Columbia, South Carolina. Lauren Gabauer is a Spanish major from Fort Mill, South Carolina. Matthew Neal '13 is a secondary math major from Rock Hill.
Published by: Winthrop University
Winthrop Student Chosen for National Exchange Program
Winthrop University
Jan 01, 0001
Senior Brooke Ashley Barber was chosen to participate in a year-long scholarship program in Germany. A native of Rock Hill, Barber is a mass communication major/German minor.
Published by: Winthrop University
Impacts of cultural dynamics on conservation of Suakin, Sudan
Katherine Sarah Ashley, Mohamed Osmani, Stephen Emmitt, Michael Mallinson, Helen Mallinson
Dec 01, 2014
The aim of this work was to explore the impact of local cultural dynamics on the conservation of the built heritage of Suakin, an abandoned historic port on the Red Sea coast of Sudan, through a collaborative stakeholder...
Laboratory informatics capacity for effective antimicrobial resistance surveillance in resource-limited settings.
Paul Turner, Priscilla Rupali, Japheth A Opintan, Walter Jaoko, Nicholas A Feasey, Sharon J Peacock, Elizabeth A Ashley
Jan 08, 2021
Antimicrobial resistance (AMR) is a major threat to human health globally. Surveillance is a key activity to determine AMR burden, impacts, and trends and to monitor effects of interventions. Surveillance systems require...
The Ursinus Weekly, April 20, 1972
Candy Silver, Lesa Spacek, Geoffrey Higgins, Carol Barenblitt, John T. Fidler, James Stellar, Judy Freelin, Carol Seifrit, Ruthann Connell
Jan 01, 0001
Ashley Montagu named Commencement speaker Joint U.S.-Canadian move sought to construct Mackenzie pipeline Women exhibit at UC, sculpture & watercolors Poll shows Americans want clean environment CCC members selected;...
Ursinus College Collegeville Pennsylvania newspaper Ashley Montagu oil pipeline Elizabeth Calhoun Barbara Zucker Campus Coordinating Committee National Wildlife Federation pollution James P. Craft Roger Caras Richard Fidler Allman Band College Union Phi Beta Kappa lacrosse Helfferich Hall gymnasium William Elliott Pool cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells
Dimitra Aravani, Kirsty Foote, Nichola Figg, Alison Finigan, Anna Uryga, Murray Clarke, Martin Bennett
Sep 30, 2020
Abstract: Vascular smooth muscle cells (VSMCs) are the main structural cell of blood vessels, and VSMC apoptosis occurs in vascular disease, after injury, and in vessel remodeling during development. Although VSMC apoptosis is...
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