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Results: 9
A comparison of various aggregation functions in multi-criteria decision analysis for drug benefit-risk assessment.
Multi-criteria decision analysis is a quantitative approach to the drug benefit-risk assessment which allows for consistent comparisons by summarising all benefits and risks in a single score. The multi-criteria decision...
A computational model of the early stages of acentriolar meiotic spindle assembly.
Gaelle Letort, Isma Bennabi, Serge Dmitrieff, François Nedelec, Marie-Hélène Verlhac, Marie-Emilie Terret
Jul 30, 2020
The mitotic spindle is an ensemble of microtubules responsible for the repartition of the chromosomal content between the two daughter cells during division. In metazoans, spindle assembly is a gradual process involving dynamic...
Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study.
Heather Ward, Gaelle Chapelais, Gunter GC Kuhnle, Robert Luben, Kay-Tee Khaw, Sheila Bingham, European Prospective into Cancer-Norfolk cohort
Jun 17, 2011
'Fight the parasite'
Francesca Porcu, Cinzia Cantacessi, Giorgia Dessì, Maria Francesca Sini, Fahad Ahmed, Lia Cavallo, Francesca Nonnis, Katherine Gibson, Cecilia Varcasia, Gaelle Joanny, Antonio Scala, Claudia Tamponi, Antonio Varcasia
Dec 08, 2022
BACKGROUND: Cystic echinococcosis (CE) is a widespread zoonosis and a significant economic concern and cause of morbidity in humans. A scarcity of education on the sources of CE infection and containment measures is considered...
Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).
Natalie Burrows, Gaelle Cane, Mathew Robson, Edoardo Gaude, William J Howat, Peter W Szlosarek, R Barbara Pedley, Christian Frezza, Margaret Ashcroft, Patrick H Maxwell
Mar 01, 2016
Animals Arginine Argininosuccinate Synthase Basic Helix-Loop-Helix Transcription Factors Blotting Western Cell Hypoxia Cell Line Tumor HCT116 Cells Humans Hydrolases Hypoxia Hypoxia-Inducible Factor 1 alpha Subunit Mechanistic Target of Rapamycin Complex 1 Mice SCID Multiprotein Complexes Neoplasms Nitric oxide Nitric Oxide Synthase Type II Perfusion Polyethylene Glycols TOR Serine-Threonine Kinases Tumor Burden Unfolded Protein Response Vascular Endothelial Growth Factor A Xenograft Model Antitumor Assays
Clara Podmore, Karina Meidtner, Matthias B Schulze, Robert A Scott, Anna Ramond, Adam S Butterworth, Emanuele Di Angelantonio, John Danesh, Larraitz Arriola, Aurelio Barricarte, Heiner Boeing, Françoise Clavel-Chapelon, Amanda J Cross, Christina C Dahm, Guy Fagherazzi, Paul W Franks, Diana Gavrila, Sara Grioni, Marc J Gunter, Gaelle Gusto, Paula Jakszyn, Verena Katzke, Timothy J Key, Tilman Kühn, Amalia Mattiello, Peter M Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, J Ramón Quirós, Olov Rolandsson, Carlotta Sacerdote, Emilio Sánchez-Cantalejo, Nadia Slimani, Ivonne Sluijs, Annemieke MW Spijkerman, Anne Tjonneland, Rosario Tumino, Daphne L van der A, Yvonne T van der Schouw, Edith JM Feskens, Nita G Forouhi, Stephen J Sharp, Elio Riboli, Claudia Langenberg, Nicholas J Wareham
Jan 22, 2016
Adult Aged Aged 80 and over Alanine Transaminase Biomarkers C-Reactive Protein Case-Control Studies Diabetes mellitus Type 2 Female Ferritins Follow-Up Studies Humans Incidence Iron Male Middle Aged Multivariate Analysis Proportional Hazards Models Prospective Studies Risk Factors Transferrin Young Adult gamma-Glutamyltransferase
Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.
Marta N Shahbazi, Antonio Scialdone, Natalia Skorupska, Antonia Weberling, Gaelle Recher, Meng Zhu, Agnieszka Jedrusik, Liani G Devito, Laila Noli, Iain C Macaulay, Christa Buecker, Yakoub Khalaf, Dusko Ilic, Thierry Voet, John C Marioni, Magdalena Zernicka-Goetz
Jun 08, 2018
The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells. In response to extracellular matrix signalling, these cells undergo epithelialization and create an apical surface in contact with a...
Amnion Animals Body Patterning Collagen Drug Combinations Embryo Mammalian Female Gene Expression Regulation Developmental Germ Layers Glycosylation Human Embryonic Stem Cells Humans Laminin Male Mice Morphogenesis Mouse embryonic stem cells Octamer Transcription Factor-3 Pluripotent Stem Cells Proteoglycans Sialomucins Spheroids Cellular
Self-organization of the human embryo in the absence of maternal tissues.
Marta N Shahbazi, Agnieszka Jedrusik, Sanna Vuoristo, Gaelle Recher, Anna Hupalowska, Virginia Bolton, Norah NM Fogarty, Alison Campbell, Liani Devito, Dusko Ilic, Yakoub Khalaf, Kathy K Niakan, Simon Fishel, Magdalena Zernicka-Goetz
Apr 13, 2016
The global antigenic diversity of swine influenza A viruses.
Nicola S Lewis, Colin A Russell, Pinky Langat, Tavis K Anderson, Kathryn Berger, Filip Bielejec, David F Burke, Gytis Dudas, Judith M Fonville, Ron AM Fouchier, Paul Kellam, Bjorn F Koel, Philippe Lemey, Tung Nguyen, Bundit Nuansrichy, Js Malik Peiris, Takehiko Saito, Gaelle Simon, Eugene Skepner, Nobuhiro Takemae, ESNIP3 consortium, Richard J Webby, Kristien Van Reeth, Sharon M Brookes, Lars Larsen, Simon J Watson, Ian H Brown, Amy L Vincent
Apr 08, 2016