Search
Results: 57
Multidirectional chromosome painting substantiates the occurrence of extensive genomic reshuffling within Accipitriformes.
Wenhui Nie, Patricia CM O'Brien, Beiyuan Fu, Jinghuan Wang, Weiting Su, Kai He, Bertrand Bed'hom, Vitaly Volobouev, Malcolm A Ferguson-Smith, Gauthier Dobigny, Fengtang Yang
Sep 29, 2016
BACKGROUND: Previous cross-species painting studies with probes from chicken (Gallus gallus) chromosomes 1-10 and a paint pool of nineteen microchromosomes have revealed that the drastic karyotypic reorganization in Accipitridae...
A transitional snake from the Late Cretaceous period of North America
Snakes are the most diverse group of lizards, but their origins and early evolution remain poorly understood owing to a lack of transitional forms. Several major issues remain outstanding, such as whether snakes originated in a...
The history of climate and society
Abstract
Recent decades have seen the rapid expansion of scholarship that identifies societal responses to past climatic fluctuations. This fast-changing scholarship, which was...
Dagomar Degroot, Kevin J Anchukaitis, Jessica E Tierney, Felix Riede, Andrea Manica, Emma Moesswilde, Nicolas Gauthier
Sep 21, 2022
A parametric model to identify hydrodynamic bearing wear at a single rotating speed
For dynamic systems, fault detection and diagnosis involve the observation of vibration signals. Faults associated with hydrodynamic bearings are one of the most common causes of forced shutdowns in rotating machinery. If it is...
A parametric model to identify hydrodynamic bearing wear at a single rotating speed
For dynamic systems, fault detection and diagnosis involve the observation of vibration signals. Faults associated with hydrodynamic bearings are one of the most common causes of forced shutdowns in rotating machinery. If it is...
Biogeography of worm lizards (Amphisbaenia) driven by end-Cretaceous mass extinction
Worm lizards (Amphisbaenia) are burrowing squamates that live as subterranean predators. Their underground existence should limit dispersal, yet they are widespread throughout the Americas, Europe and Africa. This pattern was...
A transitional snake from the Late Cretaceous period of North America
Snakes are the most diverse group of lizards, but their origins and early evolution remain poorly understood owing to a lack of transitional forms. Several major issues remain outstanding, such as whether snakes originated in a...
Biogeography of worm lizards (Amphisbaenia) driven by end-Cretaceous mass extinction
Worm lizards (Amphisbaenia) are burrowing squamates that live as subterranean predators. Their underground existence should limit dispersal, yet they are widespread throughout the Americas, Europe and Africa. This pattern was...
The history of climate and society
Abstract Recent decades have seen the rapid expansion of scholarship that identifies societal responses to past climatic fluctuations. This fast-changing scholarship, which was recently...
Early Evolution of Modern Birds Structured by Global Forest Collapse at the End-Cretaceous Mass Extinction
Daniel Field, Antoine Bercovici, Jacob S Berv, Regan Dunn, David Fastovsky, Tyler R. Lyson, Vivi Vajda, Jacques Gauthier
Jun 04, 2018
The fossil record and recent molecular phylogenies support an extraordinary early-Cenozoic radiation of crown birds (Neornithes) after the Cretaceous-Paleogene (K-Pg) mass extinction [1–3]. However, questions remain regarding...
Early Evolution of Modern Birds Structured by Global Forest Collapse at the End-Cretaceous Mass Extinction
Daniel Field, Antoine Bercovici, Jacob S Berv, Regan Dunn, David Fastovsky, Tyler R. Lyson, Vivi Vajda, Jacques Gauthier
Jun 04, 2018
The fossil record and recent molecular phylogenies support an extraordinary early-Cenozoic radiation of crown birds (Neornithes) after the Cretaceous-Paleogene (K-Pg) mass extinction [1–3]. However, questions remain regarding...
Mapping the Impact of Consumer Online Service Experience on Online Impulse Buying Behaviour
Managers of e-commerce platforms and online retail stores have noticed a connection between the consumer online service experience (COSE) and the inclination to engage in online impulse buying behaviour (OIBB). Previous research...
Published by: IGI Global Scientific Publishing
Seasonal drivers of understorey temperature buffering in temperate deciduous forests across Europe.
Florian Zellweger, David Coomes, Jonathan Lenoir, Leen Depauw, Sybryn L Maes, Monika Wulf, Keith J Kirby, Jörg Brunet, Martin Kopecký, František Máliš, Wolfgang Schmidt, Steffi Heinrichs, Jan den Ouden, Bogdan Jaroszewicz, Gauthier Buyse, Fabien Spicher, Kris Verheyen, Pieter De Frenne
Jan 29, 2020
Aim:Forest understorey microclimates are often buffered against extreme heat or cold, with important implications for the organisms living in these environments. We quantified seasonal effects of understorey microclimate...
Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments.
Nicholas P Gauthier, Boumediene Soufi, William E Walkowicz, Virginia A Pedicord, Konstantinos J Mavrakis, Boris Macek, David Y Gin, Chris Sander, Martin L Miller
Jan 24, 2018
We report a technique to selectively and continuously label the proteomes of individual cell types in coculture, named cell type-specific labeling using amino acid precursors (CTAP). Through transgenic expression of exogenous...
Circulating PCSK9 is associated with liver biomarkers and hepatic steatosis.
Martine Paquette, Dany Gauthier, Ann Chamberland, Annik Prat, Emanuella De Lucia Rolfe, Jon J Rasmussen, Lydia Kaduka, Nabil G Seidah, Sophie Bernard, Dirk L Christensen, Alexis Baass
Jan 17, 2020
BACKGROUND: In parallel to the increasing prevalence of metabolic syndrome, the prevalence of hepatic steatosis has also increased dramatically worldwide. Hepatic steatosis is a major risk factor of hepatic cirrhosis...
Clinical and biomarker trajectories in sporadic Alzheimer's disease
Hui-Fu Wang, Xue-Ning Shen, Jie-Qiong Li, John Suckling, Chen-Chen Tan, Yan-Jiang Wang, Lei Feng, Can Zhang, Lan Tan, Qiang Dong, Jacques Touchon, Serge Gauthier, Jin-Tai Yu, Alzheimer's Disease Neuroimaging Initiative
Sep 01, 2020
Introduction: Amyloid beta (Aβ) deposition was identified to precede tau pathology and neurodegeneration in familial Alzheimer's disease (AD). But the divergence between sporadic and familial AD limits the extension of these...
Seasonal drivers of understorey temperature buffering in temperate deciduous forests across Europe.
Structural basis for potency differences between GDF8 and GDF11.
Ryan G Walker, Magdalena Czepnik, Erich J Goebel, Jason C McCoy, Ana Vujic, Miook Cho, Juhyun Oh, Senem Aykul, Kelly L Walton, Gauthier Schang, Daniel J Bernard, Andrew P Hinck, Craig A Harrison, Erik Martinez-Hackert, Amy J Wagers, Richard T Lee, Thomas B Thompson
Oct 16, 2020
BACKGROUND: Growth/differentiation factor 8 (GDF8) and GDF11 are two highly similar members of the transforming growth factor β (TGFβ) family. While GDF8 has been recognized as a negative regulator of muscle growth and...
Ligands myostatin Receptor structure Transforming growth factor β (TGFβ) Amino Acid Sequence Animals Bone Morphogenetic Proteins Cells Cultured Crystallography X-Ray Follistatin Genes Reporter Growth Differentiation Factors Humans Injections Intravenous Ligands Luciferases Mice Models Molecular Myoblasts Myocardium myostatin Phosphorylation Protein Binding Protein Serine-Threonine Kinases Receptor Transforming Growth Factor-beta Type I Receptors Transforming Growth Factor beta Sequence Alignment Signal Transduction Smad Proteins Structural Homology Protein Structure-Activity Relationship
Perturbation biology
Evan J Molinelli, Anil Korkut, Weiqing Wang, Martin L Miller, Nicholas P Gauthier, Xiaohong Jing, Poorvi Kaushik, Qin He, Gordon Mills, David B Solit, Christine A Pratilas, Martin Weigt, Alfredo Braunstein, Andrea Pagnani, Riccardo Zecchina, Chris Sander
Mar 23, 2018
We present a powerful experimental-computational technology for inferring network models that predict the response of cells to perturbations, and that may be useful in the design of combinatorial therapy against cancer. The...
Physical principles of membrane remodelling during cell mechanoadaptation.
Anita Joanna Kosmalska, Laura Casares, Alberto Elosegui-Artola, Joseph Jose Thottacherry, Roberto Moreno-Vicente, Víctor González-Tarragó, Miguel Ángel Del Pozo, Satyajit Mayor, Marino Arroyo, Daniel Navajas, Xavier Trepat, Nils C Gauthier, Pere Roca-Cusachs
Jan 06, 2020
Biological processes in any physiological environment involve changes in cell shape, which must be accommodated by their physical envelope--the bilayer membrane. However, the fundamental biophysical principles by which the cell...
Validation of a new fully automated software for 2D digital mammographic breast density evaluation in predicting breast cancer risk
Paolo Giorgi Rossi, Olivera Djuric, Valerie Hélin, Susan Astley, Paola Mantellini, Andrea Nitrosi, Elaine F. Harkness, Emilien Gauthier, Donella Puliti, Corinne Balleyguier, Camille Baron, Fiona J. Gilbert, André Grivegnée, Pierpaolo Pattacini, Stefan Michiels, Suzette Delaloge
Oct 06, 2021
Abstract: We compared accuracy for breast cancer (BC) risk stratification of a new fully automated system (DenSeeMammo—DSM) for breast density (BD) assessment to a non-inferiority threshold based on radiologists’ visual...
Validation of a new fully automated software for 2D digital mammographic breast density evaluation in predicting breast cancer risk.
Paolo Giorgi Rossi, Olivera Djuric, Valerie Hélin, Susan Astley, Paola Mantellini, Andrea Nitrosi, Elaine F Harkness, Emilien Gauthier, Donella Puliti, Corinne Balleyguier, Camille Baron, Fiona J Gilbert, André Grivegnée, Pierpaolo Pattacini, Stefan Michiels, Suzette Delaloge
Oct 15, 2021
We compared accuracy for breast cancer (BC) risk stratification of a new fully automated system (DenSeeMammo-DSM) for breast density (BD) assessment to a non-inferiority threshold based on radiologists' visual assessment. Pooled...
Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration.
Joseph HR Hetmanski, Henry de Belly, Ignacio Busnelli, Thomas Waring, Roshna V Nair, Vanesa Sokleva, Oana Dobre, Angus Cameron, Nils Gauthier, Christophe Lamaze, Joe Swift, Aránzazu Del Campo, Tobias Starborg, Tobias Zech, Jacky G Goetz, Ewa K Paluch, Jean-Marc Schwartz, Patrick T Caswell
Jul 02, 2020
In development, wound healing, and cancer metastasis, vertebrate cells move through 3D interstitial matrix, responding to chemical and physical guidance cues. Protrusion at the cell front has been extensively studied, but the...
RhoGTPase Caveolae cell invasion cell migration Cytoskeleton durotaxis Extracellular Matrix membrane tension Actin Cytoskeleton Actins Animals Caveolae Cell Line Tumor Cell Membrane Cell Movement Cell Polarity Cell Surface Extensions Cytoskeleton Cytosol Extracellular Matrix Humans Mice Protein Kinase C Pseudopodia Rats Signal Transduction rho-Associated Kinases rhoA GTP-Binding Protein
|
|< |
< |
1 |