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Results: 311
Tumors Widely Express Hundreds of Embryonic Germline Genes.
Jan Willem Bruggeman, Naoko Irie, Paul Lodder, Ans MM van Pelt, Jan Koster, Geert Hamer
Dec 22, 2020
We have recently described a class of 756 genes that are widely expressed in cancers, but are normally restricted to adult germ cells, referred to as germ cell cancer genes (GC genes). We hypothesized that carcinogenesis...
Ten false beliefs in neurocritical care.
In acute brain injury, the need for specific expertise on central nervous pathophysiology is evident. However, even when the primary reason for ICU admission is extracranial, the brain may be affected too, through inadequate...
Methods for studying naturally occurring human pain and their analogues
Methods for investigating human pain have been developed over the last 100 years. Typically, researchers focus on people with clinical pain, or on healthy participants undergoing laboratory-controlled pain-induction techniques...
The efficacy of attentional distraction and sensory monitoring in chronic pain patients
Attentional strategies, such as distraction and sensory monitoring, are often offered to reduce pain and pain-related distress. However, evidence for their efficacy in chronic pain patients is equivocal. We report a...
The efficacy of attentional distraction and sensory monitoring in chronic pain patients
Attentional strategies, such as distraction and sensory monitoring, are often offered to reduce pain and pain-related distress. However, evidence for their efficacy in chronic pain patients is equivocal. We report a...
The experience of cognitive intrusion of pain
Nina Attridge, Geert Crombez, Dimitri Van Ryckeghem, Edmund Keogh, Christopher Eccleston
Oct 31, 2015
Patients with chronic pain often report their cognition to be impaired by pain, and this observation has been supported by numerous studies measuring the effects of pain on cognitive task performance. Furthermore, cognitive...
The experience of cognitive intrusion of pain
Nina Attridge, Geert Crombez, Dimitri Van Ryckeghem, Edmund Keogh, Christopher Eccleston
Oct 31, 2015
Patients with chronic pain often report their cognition to be impaired by pain, and this observation has been supported by numerous studies measuring the effects of pain on cognitive task performance. Furthermore, cognitive...
Methods for studying naturally occurring human pain and their analogues
Methods for investigating human pain have been developed over the last 100 years. Typically, researchers focus on people with clinical pain, or on healthy participants undergoing laboratory-controlled pain-induction techniques...
A deep learning approach to bilingual lexicon induction in the biomedical domain.
BACKGROUND: Bilingual lexicon induction (BLI) is an important task in the biomedical domain as translation resources are usually available for general language usage, but are often lacking in domain-specific settings. In this...
Choosing Estimands in Clinical Trials
Bohdana Ratitch, James Bell, Craig Mallinckrodt, Jonathan W Bartlett, Niti Goel, Geert Molenberghs, Michael O'Kelly, Pritibha Singh, Ilya Lipkovich
Mar 01, 2020
The National Research Council (NRC) Expert Panel Report on Prevention and Treatment of Missing Data in Clinical Trials highlighted the need for clearly defining objectives and estimands. That report sparked considerable...
Visualising the pressure-time burden of elevated intracranial pressure after severe traumatic brain injury
Joseph Donnelly, Fabian Güiza, Bart Depreitere, Geert Meyfroidt, Marek Czosnyka, Peter Smielewski
Mar 10, 2021
Atomic-to-molecular gas phase transition triggered by the radio jet in Centaurus A
NGC 5128 (Centaurus A) is one of the best example to study AGN-feedback in the local Universe. At 13.5 kpc from the galaxy, optical filaments with recent star formation are lying along the radio-jet direction. We used the...
Atomic-to-molecular gas phase transition triggered by the radio jet in Centaurus A
NGC 5128 (Centaurus A) is one of the best example to study AGN-feedback in the local Universe. At 13.5 kpc from the galaxy, optical filaments with recent star formation are lying along the radio-jet direction. We used the...
Ethylene Receptors, CTRs and EIN2 Target Protein Identification and Quantification Through Parallel Reaction Monitoring During Tomato Fruit Ripening.
Clara I Mata, Bertrand Fabre, Harriet T Parsons, Maarten LATM Hertog, Geert Van Raemdonck, Geert Baggerman, Bram Van de Poel, Kathryn S Lilley, Bart M Nicolaï
Feb 07, 2019
Ethylene, the plant ripening hormone of climacteric fruit, is perceived by ethylene receptors which is the first step in the complex ethylene signal transduction pathway. Much progress has been made in elucidating the mechanism...
Choosing Estimands in Clinical Trials
Bohdana Ratitch, James Bell, Craig Mallinckrodt, Jonathan W Bartlett, Niti Goel, Geert Molenberghs, Michael O'Kelly, Pritibha Singh, Ilya Lipkovich
Mar 01, 2020
The National Research Council (NRC) Expert Panel Report on Prevention and Treatment of Missing Data in Clinical Trials highlighted the need for clearly defining objectives and estimands. That report sparked considerable...
MUSE discovers perpendicular arcs in the inner filament of Cen A
Evidence of AGN interaction with the IGM is observed in some galaxies and many cool core clusters. Radio jets are suspected to dig large cavities into the surrounding gas. In most cases, very large optical filaments are seen...
Continuously tuneable critical current in superconductor-ferromagnet multilayers
Peter Curran, Jangyong Kim, Nathan Satchell, James Witt, Gavin Burnell, Machiel Geert Flokstra, Steve Lee, Simon Bending
Jun 27, 2017
We demonstrate that the critical current of superconducting Nb/Ni multilayers can be continuously tuned by up to a factor of three during magnetization reversal of the Ni films under an applied in-plane magnetic field. Our...
Abundancy of polymorphic CGG repeats in the human genome suggest a broad involvement in neurological disease.
Dale J Annear, Geert Vandeweyer, Ellen Elinck, Alba Sanchis-Juan, Courtney E French, Lucy Raymond, R Frank Kooy
Jan 28, 2021
Alleles Computational Biology Genetic Association Studies Genetic Predisposition to Disease Genome Human Genomic Instability Humans Microsatellite Instability Molecular Sequence Annotation Nervous System Diseases Neurodevelopmental Disorders Polymorphism Genetic Trinucleotide Repeat Expansion Trinucleotide Repeats
Continuously tuneable critical current in superconductor-ferromagnet multilayers
Peter Curran, Jangyong Kim, Nathan Satchell, James Witt, Gavin Burnell, Machiel Geert Flokstra, Steve Lee, Simon Bending
Jun 27, 2017
We demonstrate that the critical current of superconducting Nb/Ni multilayers can be continuously tuned by up to a factor of three during magnetization reversal of the Ni films under an applied in-plane magnetic field. Our...
Change in device-measured physical activity assessed in childhood and adolescence in relation to depressive symptoms
Aim: Evidence for a link between physical activity and mental health in young people is hampered by methodological shortcomings. Using repeat assessments of device-measured physical activity, we examined the association of...
MUSE discovers perpendicular arcs in the inner filament of Cen A
Evidence of AGN interaction with the IGM is observed in some galaxies and many cool core clusters. Radio jets are suspected to dig large cavities into the surrounding gas. In most cases, very large optical filaments are seen...
Change in device-measured physical activity assessed in childhood and adolescence in relation to depressive symptoms
State-of-the-art imaging for glioma surgery
Abstract: Diffuse gliomas are infiltrative primary brain tumors with a poor prognosis despite multimodal treatment. Maximum safe resection is recommended whenever feasible. The extent of resection (EOR) is positively correlated...
State-of-the-art imaging for glioma surgery.
Diffuse gliomas are infiltrative primary brain tumors with a poor prognosis despite multimodal treatment. Maximum safe resection is recommended whenever feasible. The extent of resection (EOR) is positively correlated with...
Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin
Steve Stegen, Ingrid Stockmans, Karen Moermans, Bernard Theinpont, Patrick H Maxwell, Peter Carmeliet, Geert Carmeliet
Oct 04, 2018
Acetylation Adaptor Proteins Signal Transducing Animals Bone Density Carbazoles Cell Line Coculture Techniques Disease Models Animal Epigenesis Genetic Female Glycoproteins Heterocyclic Compounds 4 or More Rings Humans Hypoxia-Inducible Factor 1 alpha Subunit Hypoxia-Inducible Factor-Proline Dioxygenases Intercellular Signaling Peptides and Proteins Male Mice Inbred C57BL Mice Transgenic Osteocytes Osteogenesis Osteoporosis Oxygen Primary Cell Culture Promoter Regions Genetic Sirtuin 1 Wnt Signaling Pathway
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