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Results: 65
Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study.
WildLab
Neural mechanisms of face perception are predominantly studied in well-controlled experimental settings that involve random stimulus sequences and fixed eye positions. Although powerful, the employed paradigms are far from what...
Numerical Modeling of a Church Nave Wall Subjected to Differential Settlements:
Anastasios Drougkas, Els Verstrynge, Pepijn Szekér, Gert Heirman, Leidy Bejarano-Urrego, Giorgia Giardina, Koen Van Balen
Jan 01, 0001
Historic masonry structures are particularly sensitive to differential soil settlements. These settlements may be caused by deformable soil, shallow or inadequate foundation, structural additions in the building and changes in...
Mapping Local Perceptions for the Planning of Cultural Landscapes
Local perceptions in the definition of cultural landscapes have been on the radar of the scientific community for a long time, but very few studies have focused on integrating this information into heritage and planning...
Published by: IGI Global Scientific Publishing
Numerical Modeling of a Church Nave Wall Subjected to Differential Settlements:
Anastasios Drougkas, Els Verstrynge, Pepijn Szekér, Gert Heirman, Leidy Bejarano-Urrego, Giorgia Giardina, Koen Van Balen
Jan 01, 0001
Historic masonry structures are particularly sensitive to differential soil settlements. These settlements may be caused by deformable soil, shallow or inadequate foundation, structural additions in the building and changes in...
A critical survey of average distances between catalytic carboxyl groups in glycoside hydrolases
Ndumiso N. Mhlongo, Adam A. Skelton, Gert Kruger, Mahmoud E. S. Soliman, Ian H. Williams
Sep 01, 2014
Published X-ray crystallographic structures for glycoside hydrolases (GHs) from 39 different families are surveyed according to some rigorous selection criteria, and the distances separating 208 pairs of catalytic carboxyl...
A critical survey of average distances between catalytic carboxyl groups in glycoside hydrolases
Ndumiso N. Mhlongo, Adam A. Skelton, Gert Kruger, Mahmoud E. S. Soliman, Ian H. Williams
Sep 01, 2014
Published X-ray crystallographic structures for glycoside hydrolases (GHs) from 39 different families are surveyed according to some rigorous selection criteria, and the distances separating 208 pairs of catalytic carboxyl...
The composition and functional protein subsystems of the human nasal microbiome in granulomatosis with polyangiitis
Josef Wagner, Ewan M Harrison, Marcos Martinez Del Pero, Beth Blane, Gert Mayer, Johannes Leierer, Seerapani Gopaluni, Mark A Holmes, Julian Parkhill, Sharon J Peacock, David RW Jayne, Andreas Kronbichler
Oct 31, 2019
ANCA GPA Metagenomics Microbiome Staphylococcus Vasculitis rRNA sequencing Adolescent Adult Aged Aged 80 and over Case-Control Studies Cohort Studies Cross-Sectional Studies Female Granulomatosis with polyangiitis Humans Male Metagenome Microbiota Middle Aged Nose Pilot Projects Staphylococcal Infections Staphylococcus Young Adult
The composition and functional protein subsystems of the human nasal microbiome in granulomatosis with polyangiitis
Josef Wagner, Ewan M. Harrison, Marcos Martinez Del Pero, Beth Blane, Gert Mayer, Johannes Leierer, Seerapani Gopaluni, Mark A. Holmes, Julian Parkhill, Sharon J. Peacock, David R. W. Jayne, Andreas Kronbichler
Oct 21, 2020
Abstract: Background: Ear, nose and throat involvement in granulomatosis with polyangiitis (GPA) is frequently the initial disease manifestation. Previous investigations have observed a higher prevalence of Staphylococcus aureus...
Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies.
Stephen M Kissler, Joseph R Fauver, Christina Mack, Scott W Olesen, Caroline Tai, Kristin Y Shiue, Chaney C Kalinich, Sarah Jednak, Isabel M Ott, Chantal BF Vogels, Jay Wohlgemuth, James Weisberger, John DiFiori, Deverick J Anderson, Jimmie Mancell, David D Ho, Nathan D Grubaugh, Yonatan H Grad
Sep 14, 2021
SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and can be followed by low-level persistent viral RNA shedding. The dynamics of viral RNA concentration, particularly in the early stages of...
Antibody mediated neutralization of myelin associated EphrinB3 accelerates CNS remyelination
Core outcome set measurement for future clinical trials in acute myeloid leukemia
Katharina M Lang, Kathryn L Harrison, Paula R Williamson, Brian JP Huntly, Gert Ossenkoppele, Jan Geissler, Tamàs Bereczky, Jesús M Hernández-Rivas, Hélène Chevrou-Séverac, Rory Goodbody, Renate Schulze-Rath, Lars Bullinger
Jul 03, 2020
BACKGROUND: Acute myeloid leukemia (AML) is the most common acute leukemia in adults and has an unacceptably low cure rate. In recent years, a number of new treatment strategies and compounds were developed for the treatment of...
Calling on a million minds for community annotation in WikiProteins.
Barend Mons, Michael Ashburner, Christine Chichester, Erik van Mulligen, Marc Weeber, Johan den Dunnen, Gert-Jan van Ommen, Mark Musen, Matthew Cockerill, Henning Hermjakob, Albert Mons, Abel Packer, Roberto Pacheco, Suzanna Lewis, Alfred Berkeley, William Melton, Nickolas Barris, Jimmy Wales, Gerard Meijssen, Erik Moeller, Peter Jan Roes, Katy Borner, Amos Bairoch
Jun 17, 2011
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus
WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming.
Core outcome set measurement for future clinical trials in acute myeloid leukemia
Katharina M. Lang, Kathryn L. Harrison, Paula R. Williamson, Brian J. P. Huntly, Gert Ossenkoppele, Jan Geissler, Tamàs Bereczky, Jesús M. Hernández-Rivas, Hélène Chevrou-Séverac, Rory Goodbody, Renate Schulze-Rath, Lars Bullinger
May 27, 2021
Abstract: Background: Acute myeloid leukemia (AML) is the most common acute leukemia in adults and has an unacceptably low cure rate. In recent years, a number of new treatment strategies and compounds were developed for the...
A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis
Trang Hieu Nguyen, Louis Thiers, Alex Van Moerkercke, Yuechen Bai, Patricia Fernández-Calvo, Max Minne, Thomas Depuydt, Maite Colinas, Kevin Verstaen, Gert Van Isterdael, Hans Wilhelm Nützmann, Anne Osbourn, Yvan Saeys, Bert De Rybel, Klaas Vandepoele, Andrés Ritter, Alain Goossens
Jun 01, 2023
Plant specialized metabolites modulate developmental and ecological functions and comprise many therapeutic and other high-value compounds. However, the mechanisms determining their cell-specific expression remain unknown....
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use
Jonathan Scott, Loredana Trevi, Hannah McNeil, Tom Ewen, Phil Mawson, David McDonald, Andrew Filby, Ranjit Lall, Katie Booth, Gert Boschman, Vesna Melkebeek, Gavin Perkins, Ronan McMullan, Daniel F McAuley, Iain J McCullagh, Timothy Walsh, Anthony Rostron, Manu Shankar-Hari, Paul Dark, A John Simpson, Andrew Conway Morris, Thomas P Hellyer
Feb 09, 2023
INTRODUCTION: Sepsis is characterised by a dysregulated immune response to infection, with exaggerated pro-inflammatory and anti-inflammatory responses. A predominant immunosuppressive profile affecting both innate and adaptive...
Core outcome set measurement for future clinical trials in acute myeloid leukemia
Katharina M. Lang, Kathryn L. Harrison, Paula R. Williamson, Brian J. P. Huntly, Gert Ossenkoppele, Jan Geissler, Tamàs Bereczky, Jesús M. Hernández-Rivas, Hélène Chevrou-Séverac, Rory Goodbody, Renate Schulze-Rath, Lars Bullinger
Jun 06, 2020
Abstract: Background: Acute myeloid leukemia (AML) is the most common acute leukemia in adults and has an unacceptably low cure rate. In recent years, a number of new treatment strategies and compounds were developed for the...
A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis
Trang Hieu Nguyen, Louis Thiers, Alex Van Moerkercke, Yuechen Bai, Patricia Fernández-Calvo, Max Minne, Thomas Depuydt, Maite Colinas, Kevin Verstaen, Gert Van Isterdael, Hans Wilhelm Nützmann, Anne Osbourn, Yvan Saeys, Bert De Rybel, Klaas Vandepoele, Andrés Ritter, Alain Goossens
Jun 01, 2023
Plant specialized metabolites modulate developmental and ecological functions and comprise many therapeutic and other high-value compounds. However, the mechanisms determining their cell-specific expression remain unknown....
Probabilistic identification of cerebellar cortical neurones across species.
Gert Van Dijck, Marc M Van Hulle, Shane A Heiney, Pablo M Blazquez, Hui Meng, Dora E Angelaki, Alexander Arenz, Troy W Margrie, Abteen Mostofi, Steve Edgley, Fredrik Bengtsson, Carl-Fredrik Ekerot, Henrik Jörntell, Jeffrey W Dalley, Tahl Holtzman
Jan 11, 2021
Despite our fine-grain anatomical knowledge of the cerebellar cortex, electrophysiological studies of circuit information processing over the last fifty years have been hampered by the difficulty of reliably assigning signals to...
Plant development. Arabidopsis NAC45/86 direct sieve element morphogenesis culminating in enucleation.
Kaori Miyashima Furuta, Shri Ram Yadav, Satu Lehesranta, Ilya Belevich, Shunsuke Miyashima, Jung-Ok Heo, Anne Vatén, Ove Lindgren, Bert De Rybel, Gert Van Isterdael, Panu Somervuo, Raffael Lichtenberger, Raquel Rocha, Siripong Thitamadee, Sari Tähtiharju, Petri Auvinen, Tom Beeckman, Eija Jokitalo, Ykä Helariutta
Nov 04, 2019
Photoassimilates such as sugars are transported through phloem sieve element cells in plants. Adapted for effective transport, sieve elements develop as enucleated living cells. We used electron microscope imaging and...
What is influencing the phenotype of the common homozygous polymerase-γ mutation p.Ala467Thr?
Vivienne CM Neeve, David C Samuels, Laurence A Bindoff, Bianca van den Bosch, Gert Van Goethem, Hubert Smeets, Anne Lombès, Claude Jardel, Michio Hirano, Salvatore DiMauro, Maaike De Vries, Jan Smeitink, Bart W Smits, Ireneus FM de Coo, Carsten Saft, Thomas Klopstock, Bianca-Cortina Keiling, Birgit Czermin, Angela Abicht, Hanns Lochmüller, Gavin Hudson, Grainne G Gorman, Doug M Turnbull, Robert W Taylor, Elke Holinski-Feder, Patrick F Chinnery, Rita Horvath
Mar 07, 2019
Polymerase-γ (POLG) is a major human disease gene and may account for up to 25% of all mitochondrial diseases in the UK and in Italy. To date, >150 different pathogenic mutations have been described in POLG. Some mutations...
Adolescent Adult Age of Onset Alanine Child Cohort Studies DNA Mutational Analysis DNA Polymerase gamma DNA-Directed DNA Polymerase Diffuse Cerebral Sclerosis of Schilder Europe Family Health Female Genetic Predisposition to Disease Homozygote Humans Male Middle Aged Mitochondrial Diseases Muscle Skeletal Mutation Ophthalmoplegia Chronic Progressive External Statistics as Topic statistics Nonparametric Threonine Young Adult
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