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Convergence of interaction-driven evolutions of dislocations with Wasserstein dissipation and slip-plane confinement
We consider systems of n parallel edge dislocations in a single slip system, represented by points in a two-dimensional domain; the elastic medium is modelled as a continuum. We formulate the energy of this system in terms of...
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Convergence of interaction-driven evolutions of dislocations with Wasserstein dissipation and slip-plane confinement
We consider systems of n parallel edge dislocations in a single slip system, represented by points in a two-dimensional domain; the elastic medium is modelled as a continuum. We formulate the energy of this system in terms of...
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The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway.
The unfolded protein response (UPR) is a highly conserved protein quality control mechanism, activated in response to Endoplasmic Reticulum (ER) stress. Signalling is mediated through three branches, PERK, IRE1, and ATF6...
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Tool wear classification using time series imaging and deep learning
Abstract: Tool condition monitoring (TCM) has become essential to achieve high-quality machining as well as cost-effective production. Identification of the cutting tool state during machining before it reaches its failure stage...
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Tensile Strength of Artificially Cemented Sandstone Generated via Microbially Induced Carbonate Precipitation
Artificially bio-cemented sands treated with microbially induced calcite precipitation are weakly cemented rocks representing intermediate materials between locked and carbonate sands. Variations in cementation significantly...
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The equilibrium measure for a nonlocal dislocation energy

In this paper we characterize the equilibrium measure for a nonlocal and anisotropic weighted energy describing the interaction of positive dislocations in the plane. We prove that the minimum value of the energy is attained...

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Prions
Neurodegenerative diseases are characterized by the aggregation of misfolded proteins in the brain. Among these disorders are the prion diseases, which are transmissible, and in which the misfolded proteins ("prions") are also...
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Tool wear classification using time series imaging and deep learning
Tool condition monitoring (TCM) has become essential to achieve high-quality machining as well as cost-effective production. Identification of the cutting tool state during machining before it reaches its failure stage is...
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Reply: Trazodone to change the risk of neurodegeneration
We were interested to read the authors’ comments our recent paper in Brain (Halliday et al., 2017). We agree that carefully designed phase II and phase III trials would be needed to test the efficacy of trazodone as a treatment...
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Multilayer modelling of the human transcriptome and biological mechanisms of complex diseases and traits.
Here, we performed a comprehensive intra-tissue and inter-tissue multilayer network analysis of the human transcriptome. We generated an atlas of communities in gene co-expression networks in 49 tissues (GTEx v8), evaluated...
Multilayer modelling of the human transcriptome and biological mechanisms of complex diseases and traits.
Here, we performed a comprehensive intra-tissue and inter-tissue multilayer network analysis of the human transcriptome. We generated an atlas of communities in gene co-expression networks in 49 tissues (GTEx v8), evaluated...
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Splenial white matter integrity is associated with memory impairments in posterior cortical atrophy.
Posterior cortical atrophy is an atypical form of Alzheimer's disease characterized by visuospatial impairments and predominant tissue loss in the posterior parieto-occipital and temporo-occipital cortex. Whilst episodic memory...
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The equilibrium measure for a nonlocal dislocation energy

In this paper we characterize the equilibrium measure for a nonlocal and anisotropic weighted energy describing the interaction of positive dislocations in the plane. We prove that the minimum value of the energy is attained...

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Physiologically based modelling of the antiplatelet effect of aspirin
A computational approach involving mathematical modeling and in silico experiments was used to characterize the determinants of extent and duration of platelet cyclooxygenase (COX)-1 inhibition by aspirin and design precision...
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