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Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.
Claudio Mauro, Joanne Smith, Danilo Cucchi, David Coe, Hongmei Fu, Fabrizia Bonacina, Andrea Baragetti, Gaia Cermenati, Donatella Caruso, Nico Mitro, Alberico L Catapano, Enrico Ammirati, Maria P Longhi, Klaus Okkenhaug, Giuseppe D Norata, Federica M Marelli-Berg
Jun 27, 2018
Low-grade systemic inflammation associated to obesity leads to cardiovascular complications, caused partly by infiltration of adipose and vascular tissue by effector T cells. The signals leading to T cell differentiation and...
Akt CD4 T lymphocyte DIFFERENTIATION effector memory High-fat diet Inflammation obesity palmitate saturated fatty acid Adiposity Animals Antigen Presentation CD4-Positive T-Lymphocytes Cell Differentiation Cell Movement Dendritic Cells Diet High-Fat Fatty Acids Female Humans Immunologic Memory Inflammation Lymphocyte Activation Lymphoid Tissue Male Mice Inbred C57BL obesity Oxidation-Reduction Phenotype Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Receptors CXCR3 Signal Transduction Stress Physiological
Abdominal versus perineal approach for external rectal prolapse
Gianluca Pellino, Giacomo Fuschillo, Costantinos Simillis, Lucio Selvaggi, Giuseppe Signoriello, Danilo Vinci, Christos Kontovounisios, Francesco Selvaggi, Guido Sciaudone
May 09, 2022
BACKGROUND: External rectal prolapse (ERP) is a debilitating condition in which surgery plays an important role. The aim of this study was to evaluate the outcomes of abdominal approaches (AA) and perineal approaches (PA) to...
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.
Madhav Kishore, Kenneth CP Cheung, Hongmei Fu, Fabrizia Bonacina, Guosu Wang, David Coe, Eleanor J Ward, Alessandra Colamatteo, Maryam Jangani, Andrea Baragetti, Giuseppe Matarese, David M Smith, Robert Haas, Claudio Mauro, David C Wraith, Klaus Okkenhaug, Alberico L Catapano, Veronica De Rosa, Giuseppe D Norata, Federica M Marelli-Berg
Jan 24, 2018
Migration of activated regulatory T (Treg) cells to inflamed tissue is crucial for their immune-modulatory function. While metabolic reprogramming during Treg cell differentiation has been extensively studied, the bioenergetics...
CD28 CTLA-4 Glycolysis mTOR metabolism Migration regulatory T cells Adaptor Proteins Signal Transducing Animals CD28 Antigens CTLA-4 Antigen Cells Cultured glucokinase Glycolysis Humans Mechanistic Target of Rapamycin Complex 1 Mechanistic Target of Rapamycin Complex 2 Mice Mice Inbred Strains Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt T-Lymphocytes Regulatory
Regularization of Inverse Problems
Variational regularization methods are commonly used to approximate solutions of inverse problems. In recent years, model-based variational regularization methods have often been replaced with data-driven ones such as the...
An Interpretative View on Innovation Acceptance for Bitcoin and Blockchain Phenomena
The research, in its general lines, tends to open an interpretative perspective on the fact that the bitcoin and blockchain (BTC-BC) phenomenon could be defined primarily through the social learning lens, and in that case would...
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
Fish consumption and frying of fish in relation to type 2 diabetes incidence
Alice Wallin, Daniela Di Giuseppe, Nicola Orsini, Agneta Åkesson, Nita G Forouhi, Alicja Wolk
Jan 13, 2016
cohort study fish Fried foods Methyl mercury Polychlorinated biphenyls Type 2 diabetes Aged Animals Cohort Studies Cooking Diabetes mellitus Type 2 Diet Healthy Diet High-Fat Fishes Follow-Up Studies Food Contamination Humans Incidence Male Methylmercury Compounds Middle Aged Patient Compliance Polychlorinated Biphenyls Proportional Hazards Models Prospective Studies Registries seafood Shellfish Sweden Water Pollutants
An Analysis of Route Duration Times in Vehicular Networks Considering Influential Factors
Vehicular ad hoc networks (VANETs) are part of intelligent transportation systems (ITS) and their main objective is to provide communication between vehicles. As self-organizing and configuring networks, with decentralized...
Published by: IGI Global Scientific Publishing
Regularization of Inverse Problems
Variational regularization methods are commonly used to approximate solutions of inverse problems. In recent years, model-based variational regularization methods have often been replaced with data-driven ones such as the...
Wavelet pressure reactivity index
Xiuyun Liu, Marek Czosnyka, Joseph Donnelly, Danilo Cardim, Manuel Cabeleira, Peter J Hutchinson, Xiao Hu, Peter Smielewski, Ken Brady
Nov 21, 2018
KEY POINTS: The brain is vulnerable to damage from too little or too much blood flow. A physiological mechanism termed cerebral autoregulation (CA) exists to maintain stable blood flow even if cerebral perfusion pressure (CPP)...
Efficient Syntheses of Biobased Terephthalic Acid, p-Toluic Acid, and p-Methylacetophenone via One-Pot Catalytic Aerobic Oxidation of Monoterpene Derived Bio-p-cymene.
An efficient elevated-pressure catalytic oxidative process (2.5 mol % Co(NO3)2, 2.5 mol % MnBr2, air (30 bar), 125 °C, acetic acid, 6 h) has been developed to oxidize p-cymene into crystalline white terephthalic acid (TA) in...
The Lantern Vol. 73, No. 1, Fall 2005
Daniel Sergeant, Nathan Dawley, Katy Diana, Klaus Yoder, Brad Schutts, Trevor Strunk, Joshua Solomon, Patrick Roesle, Thomas Richter, Jennifer Mingolello, Nathan Dawley, Tori Wynne, Tracey Ferdinand, Natalie Rokaski, Katherine Jones, Elsa Budzowski, Brett Celinski, Ashley Higgins
Jan 01, 0001
Newspaper Clippings Found on the Wall of Giuseppe Luchenzo's Home When it was Raided by Police All the Time in the World The Man Who Would Win Souffle Suit A Day in the Mind Context Felicity / Awareness ...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Cerebrovascular assessment of patients undergoing shoulder surgery in beach chair position using a multiparameter transcranial Doppler approach.
Danilo Cardim, Chiara Robba, Basil Matta, Graham Tytherleigh-Strong, Niel Kang, Bernhard Schmidt, Joseph Donnelly, Leanne Calviello, Peter Smielewski, Marek Czosnyka
Nov 22, 2018
Beach chair position cerebral autoregulation Non-invasive intracranial pressure Transcranial Doppler Adolescent Adult Aged Aged 80 and over Anesthesia Arterial Pressure Blood Flow Velocity Brain Brain Ischemia Cerebrovascular Circulation Female Hemodynamics Humans Male Middle Aged Monitoring Physiologic Oxygen Patient Positioning Propofol risk Shoulder Sitting Position Ultrasonography Doppler Ultrasonography Doppler Transcranial Young Adult
Transcranial Doppler-derived indices of cerebrovascular haemodynamics are independent of depth and angle of insonation.
Michael Heckelmann, Ganeshwaran Shivapathasundram, Danilo Cardim, Peter Smielewski, Marek Czosnyka, Rita Gaio, Mark MP Sheridan, Matthias Jaeger
Nov 24, 2020
Continuous measurement of cerebral blood flow velocity (CBFV) of the middle cerebral artery (MCA) using transcranial Doppler (TCD) and arterial blood pressure (ABP) monitoring enables assessment of cerebrovascular haemodynamics....
cerebral autoregulation Mean index Monitoring Transcranial Doppler Ultrasonography Adult Aged Aged 80 and over Algorithms Blood Flow Velocity Cerebrovascular Circulation Female Hemodynamics Homeostasis Humans Image Interpretation Computer-Assisted Male Middle Aged Middle Cerebral Artery Ultrasonography Doppler Transcranial
Photodegradation and ecotoxicology of acyclovir in water under UV254 and UV 254/H2O2 processes
Danilo Russo, Antonietta Siciliano, Marco Guida, Emilia Galdiero, Angela Amoresano, Roberto Andreozzi, Nuno Reis, Gianluca Li Puma, Raffaele Marotta
Oct 01, 2017
The photochemical and ecotoxicological fate of acyclovir (ACY) through UV254 direct photolysis and in the presence of hydroxyl radicals (UV254/H2O2 process) were investigated in a microcapillary film (MCF) array photoreactor...
Nitrogen and chlorophyll status determination in durum wheat as influenced by fertilization and soil management
Marco Fiorentini, Stefano Zenobi, Elisabetta Giorgini, Danilo Basili, Carla Conti, Chiara Pro, Elga Monaci, Roberto Orsini
Jan 20, 2020
Handheld chlorophyll meters as Soil Plant Analysis Development (SPAD) have proven to be useful tools for rapid, no-destructive assessment of chlorophyll and nitrogen status in various crops. This method is used to diagnose the...
Efficient Syntheses of Biobased Terephthalic Acid, p-Toluic Acid and p-Methylacetophenone via One-Pot Catalytic Aerobic Oxidation of Monoterpene Derived bio-p-Cymene
An efficient elevated-pressure catalytic oxidative process (2.5 mol % Co(NO3)2, 2.5 mol % MnBr2, air (30 bar), 125 °C, acetic acid, 6 h) has been developed to oxidize p-cymene into crystalline white terephthalic acid (TA) in...
Bio- p-cymene Bio- p-methylacetophenone Bio- p-toluic acid Bio-terephthalic acid Catalytic aerobic oxidation Terpene biorefinery /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Transcranial Doppler Non-invasive Assessment of Intracranial Pressure, Autoregulation of Cerebral Blood Flow and Critical Closing Pressure during Orthotopic Liver Transplant.
Danilo Cardim, Chiara Robba, Eric Schmidt, Bernhard Schmidt, Joseph Donnelly, John Klinck, Marek Czosnyka
Apr 16, 2019
Transcranial Doppler (TCD) ultrasonography allows continuous non-invasive monitoring of cerebral blood flow velocity in a variety of clinical conditions. Recently, signal processing of TCD signals has provided several...
Cerebral oedema cerebral perfusion pressure Liver Failure Neuromonitoring Transcranial Doppler Aged Cerebrovascular Circulation Female Homeostasis Humans Intracranial Pressure Liver Transplantation Male Middle Aged Middle Cerebral Artery Monitoring Intraoperative Retrospective Studies Ultrasonography Doppler Transcranial
Determining the cost-effectiveness requirements of an exoskeleton preventing second hip fractures using value of information
Abstract: Background: Falls may lead to hip fractures, which have a detrimental effect on the prognosis of patients as well as a considerable impact on healthcare expenditures. Since a secondary hip fracture (SHF) may lead to...
Non-invasive Monitoring of Intracranial Pressure Using Transcranial Doppler Ultrasonography
Danilo Cardim, C Robba, M Bohdanowicz, J Donnelly, B Cabella, X Liu, M Cabeleira, P Smielewski, B Schmidt, M Czosnyka
Feb 19, 2016
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