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BOLD Coupling between Lesioned and Healthy Brain Is Associated with Glioma Patients’ Recovery
Rafael Romero-Garcia, Michael G. Hart, Richard A. I. Bethlehem, Ayan Mandal, Moataz Assem, Benedicto Crespo-Facorro, Juan Manuel Gorriz, Gladstone Austin Amos Burke, Stephen J. Price, Thomas Santarius, Yaara Erez, John Suckling
Oct 07, 2021
Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, interlocking brain networks that underpin cognition. The aim of this study was to test glioma functional...
The people of the Cambridge Austin friars.
The Austin friars in Cambridge was an important religious institution between the late thirteenth and mid-sixteenth centuries. Excavations have revealed well-dated and contextualised burials associated with the friary, as well...
Published by: Archaeological journal
Parliamentarism
William Selinger’s Parliamentarism: from Burke to Weber aims to redefine our understanding of what it means to live in a free state. It displaces the concept of “democracy” as a (supposedly) central concern for a range...
Anna Plassart
Aug 19, 2022
Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.
Non-Hodgkin lymphoma (NHL) is the third most common malignancy diagnosed in children. The vast majority of paediatric NHL are either Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL), anaplastic large cell lymphoma...
Prevention of radiotherapy-induced neurocognitive dysfunction in survivors of paediatric brain tumours
Neurocognitive dysfunction is the leading cause of reduced quality of life in long-term survivors of paediatric brain tumours. Radiotherapy is one of the main contributors to neurocognitive sequelae. Current approaches for...
Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
Arginase has therapeutic potential as a cytotoxic agent in some cancers, but this is unclear for precursor B acute lymphoblastic leukaemia (pre-B ALL), the commonest form of childhood leukaemia. We compared arginase cytotoxicity...
From bench to bedside
Children's Oncology Group European Inter-Group for Childhood non-Hodgkin Lymphoma anaplastic large cell lymphoma Anaplastic Lymphoma Kinase anaplastic lymphoma kinase inhibitors Anaplastic Lymphoma Kinase Biomarkers Tumor Child Combined Modality Therapy Disease Management Humans Lymphoma Large-Cell Anaplastic Molecular Targeted Therapy Prognosis Protein Kinase Inhibitors Translational Research Biomedical Treatment Outcome
Vinblastine monotherapy induction prior to radiotherapy for patients with intracranial germinoma during the COVID-19 pandemic.
Matthew J Murray, Rafael Moleron, Jennifer Adamski, Martin English, GA Amos Burke, Justin Cross, Thankamma Ajithkumar, Sara Stoneham, James C Nicholson
Sep 07, 2021
BACKGROUND: Patients with localized intracranial germinoma have excellent survival. Reducing treatment burden and long-term sequelae is a priority. Intensive inpatient chemotherapy (e.g....
Treatment Options for Paediatric Anaplastic Large Cell Lymphoma (ALCL)
Anaplastic Lymphoma Kinase (ALK)-positive Anaplastic Large Cell Lymphoma (ALCL), remains one of the most curable cancers in the paediatric setting; multi-agent chemotherapy cures approximately 65-90% of patients. Over the last...
Paediatric Burkitt lymphoma patient-derived xenografts capture disease characteristics over time and are a model for therapy.
Sorcha Forde, Jamie D Matthews, Leila Jahangiri, Liam C Lee, Nina Prokoph, Tim IM Malcolm, Olivier T Giger, Natalie Bell, Helen Blair, Aengus O'Marcaigh, Owen Smith, Lukas Kenner, Simon Bomken, Gladstone AA Burke, Suzanne D Turner
Jul 31, 2020
Unrecognised Outbreak
Anna Smielewska, Callum Pearson, Ashley Popay, Iain Roddick, Mark Reacher, Edward Emmott, Jenny He, Rachel Thaxter, Carol Chenery, Ian Goodfellow, Amos Burke, Hamid Jalal
Mar 19, 2019
Background: Human parainfluenza viruses (HPIVs) are significant causes of both upper and lower respiratory tract infections with type 3 (HPIV3) causing the most severe disease in the immunocompromised cohorts. The objective of...
BOLD Coupling between Lesioned and Healthy Brain Is Associated with Glioma Patients' Recovery.
Rafael Romero-Garcia, Michael G Hart, Richard AI Bethlehem, Ayan Mandal, Moataz Assem, Benedicto Crespo-Facorro, Juan Manuel Gorriz, GA Amos Burke, Stephen J Price, Thomas Santarius, Yaara Erez, John Suckling
Oct 05, 2021
Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, interlocking brain networks that underpin cognition. The aim of this study was to test glioma functional...
Memory recovery in relation to default mode network impairment and neurite density during brain tumor treatment.
Clinical utility of vinblastine therapeutic drug monitoring for the treatment of infantile myofibroma patients
Vickyanne Carruthers, Shelby Barnett, Rebecca Rees, Tasnim Arif, Olga Slater, Ramya Ramanujachar, Katie Johnson, Sarah Brown, Catherine Graham, GA Amos Burke, Gareth J Veal
Apr 20, 2022
Infantile myofibroma is a rare, benign tumour of infancy typically managed surgically. In a minority of cases, more aggressive disease is seen and chemotherapy with vinblastine and methotrexate may be used, although evidence for...
What is conservatism? History, ideology and party
Is there a political philosophy of conservatism? A history of the phenomenon written along sceptical lines casts doubt on the existence of a transhistorical doctrine, or even an enduring conservative outlook. The main...
Richard Bourke
Dec 19, 2018
BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL.
Gavin D Garland, Stephen P Ducray, Leila Jahangiri, Perla Pucci, GA Amos Burke, Jack Monahan, Raymond Lai, Olaf Merkel, Ana-Iris Schiefer, Lukas Kenner, Andrew J Bannister, Suzanne D Turner
Jan 07, 2022
Anaplastic large-cell lymphoma (ALCL) is a T-cell malignancy driven in many cases by the product of a chromosomal translocation, nucleophosmin-anaplastic lymphoma kinase (NPM-ALK). NPM-ALK activates a plethora of pathways that...
Clonal hematopoiesis and therapy-related myeloid neoplasms following neuroblastoma treatment.
Tim HH Coorens, Grace Collord, Wanhua Lu, Emily Mitchell, Jannat Ijaz, Thomas Roberts, Thomas RW Oliver, GA Amos Burke, Michael Gattens, Emmy Dickens, Jyoti Nangalia, Marc Tischkowitz, John Anderson, Adam Shlien, Anna L Godfrey, Matthew J Murray, Sam Behjati
Feb 05, 2021
Therapy-related myeloid neoplasms (TMN) constitute one of the most challengingcomplications of cancer treatment.1 Whilst understanding of TMN pathogenesis remains fragmentary, genomic studies in adults have thus far refuted the...
BOLD Coupling between Lesioned and Healthy Brain Is Associated with Glioma Patients' Recovery.
Rafael Romero-Garcia, Michael G Hart, Richard A I Bethlehem, Ayan Mandal, Moataz Assem, Benedicto Crespo-Facorro, Juan Manuel Gorriz, G A Amos Burke, Stephen J Price, Thomas Santarius, Yaara Erez, John Suckling
Nov 22, 2021
Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, interlocking brain networks that underpin cognition. The aim of this study was to test glioma functional...
Published by: Cancers
Rare non-Hodgkin lymphoma of childhood and adolescence
Andishe Attarbaschi, Oussama Abla, Laura Arias Padilla, Auke Beishuizen, GA Amos Burke, Laurence Brugières, Julie Bruneau, Birgit Burkhardt, Emanuele SG d'Amore, Wolfram Klapper, Udo Kontny, Marta Pillon, Mary Taj, Suzanne D Turner, Anne Uyttebroeck, Wilhelm Woessmann, Karin Mellgren
May 04, 2020
Pediatric-type follicular (PTFL), marginal zone (MZL), and peripheral T-cell lymphoma (PTCL) account each for <2% of childhood non-Hodgkin lymphoma. We present clinical and histopathological features of PTFL, MZL, and few...
The NHS England 100,000 Genomes Project
Jamie Trotman, Ruth Armstrong, Helen Firth, Claire Trayers, James Watkins, Kieren Allinson, Thomas S Jacques, James C Nicholson, GA Amos Burke, Genomics England Research Consortium, Sam Behjati, Matthew J Murray, Catherine E Hook, Patrick Tarpey
Jul 14, 2022
Organizing the Online Course
Kathleen A Burke, Ms.
Jan 01, 0001
If you are new to online instruction or are a veteran looking for fresh ideas for designing your online courses, this presentation will demonstrate user-friendly design for online courses, including course menu links...
Redundancy Orientation communications discussion organization Arts and Humanities Education Higher Education and Teaching Scholarship of Teaching and Learning
Published by: Winthrop University
Anti-ALK Antibodies in Patients with ALK-Positive Malignancies Not Expressing NPM-ALK.
The Role of social workers in Welfare-to-Work programs
Welfare-to-work is an important arena for understanding the changing nature of social policy and practice in Australia, the UK, Hong Kong, and the United States. This article discusses some key policy and practice issues...
The Role of social workers in Welfare-to-Work programs
Welfare-to-work is an important arena for understanding the changing nature of social policy and practice in Australia, the UK, Hong Kong, and the United States. This article discusses some key policy and practice issues...
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