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Results: 36
A qualitative study of online mental health information seeking behaviour by those with psychosis.
Golnar Aref-Adib, Puffin O'Hanlon, Kate Fullarton, Nicola Morant, Andrew Sommerlad, Sonia Johnson, David Osborn
Sep 29, 2016
BACKGROUND: The Internet and mobile technology are changing the way people learn about and manage their illnesses. Little is known about online mental health information seeking behaviour by people with psychosis. This paper...
Caudwell Xtreme Everest
Konstadina Griva, Jan Stygall, Mark H Wilson, Daniel Martin, Denny Levett, Kay Mitchell, Monty Mythen, Hugh E Montgomery, Mike P Grocott, Golnar Aref-Adib, Mark Edsell, Tracie Plant, Chris Imray, Debbie Cooke, Jane Harrington, Maryam Khosravi, Stanton P Newman, Caudwell Xtreme Everest Research Group
Feb 22, 2019
BACKGROUND: The neuropsychological consequences of exposure to environmental hypobaric hypoxia (EHH) remain unclear. We thus investigated them in a large group of healthy volunteers who trekked to Mount Everest base camp (5,300...
The Interdependence of Family Stability and Environment
This policy brief presents the policy implications on the complex interplay between family stability and environmental sustainability. It analyzes both factors as both influencing and being influenced by each...
The Interdependence of Family Stability and Environment
This policy brief presents the policy implications on the complex interplay between family stability and environmental sustainability. It analyzes both factors as both influencing and being influenced by each...
Critical review of family well-being and cohesion indexes
The absence of measurable indicators for family well-being poses significant challenges in the Arab context. Without a standardized framework for assessment, it becomes difficult to identify areas of concern and allocate...
Vinculin recruitment to α-catenin halts the differentiation and maturation of enterocyte progenitors to maintain homeostasis of the Drosophila intestine.
Mechanisms communicating changes in tissue stiffness and size are particularly relevant in the intestine because it is subject to constant mechanical stresses caused by peristalsis of its variable content. Using the Drosophila...
Critical review of family well-being and cohesion indexes
The absence of measurable indicators for family well-being poses significant challenges in the Arab context. Without a standardized framework for assessment, it becomes difficult to identify areas of concern and allocate...
Social Protection Reforms in the Mena Region
The COVID-19 crisis revealed a significant gap in access to public services and highlighted significant issues with regards to government responsiveness to the immediate consequences of the pandemic. In the Middle East and North...
Published by: EU
The State of Urbanization, Demographic Changes, and Family Dynamics in Africa
Rapid urbanization and population growth in Africa, coupled with the complex interplay between changing demographics, have resulted in significant implications for families. Using secondary sources, this desk review explores...
Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila.
Drosophila Hippo signaling JNK signaling adenomatous polyposis coli (APC) Apoptosis Cancer cell competition Cell Death intestinal adenomas posterior midgut Tumor Microenvironment Adenoma Animals Carcinogenesis Cell Proliferation Cell Transformation Neoplastic Disease Models Animal Drosophila melanogaster Humans Intestinal Neoplasms Signal Transduction
Vinculin recruitment to α-catenin halts the differentiation and maturation of enterocyte progenitors to maintain homeostasis of the Drosophila intestine
RESEARCH ARTICLE developmental biology Stem Cells and Regenerative Medicine Vinculin intestinal homeostasis DIFFERENTIATION stem cell Mechanotransduction D. melanogaster
Published by: eLife Sciences Publications, Ltd
Social Protection Reforms in the Mena Region
The COVID-19 crisis revealed a significant gap in access to public services and highlighted significant issues with regards to government responsiveness to the immediate consequences of the pandemic. In the Middle East and North...
Published by: EU
The State of Urbanization, Demographic Changes, and Family Dynamics in Africa
Rapid urbanization and population growth in Africa, coupled with the complex interplay between changing demographics, have resulted in significant implications for families. Using secondary sources, this desk review explores...
A multilayer circuit architecture for the generation of distinct locomotor behaviors in Drosophila.
Animals generate diverse motor behaviors, yet how the same motor neurons (MNs) generate two distinct or antagonistic behaviors remains an open question. Here, we characterize Drosophila larval muscle activity patterns and...
MDN brain descending neurons coordinately activate backward and inhibit forward locomotion.
Arnaldo Carreira-Rosario, Aref Arzan Zarin, Matthew Q Clark, Laurina Manning, Richard D Fetter, Albert Cardona, Chris Q Doe
Nov 22, 2018
Command-like descending neurons can induce many behaviors, such as backward locomotion, escape, feeding, courtship, egg-laying, or grooming (we define 'command-like neuron' as a neuron whose activation elicits or 'commands' a...
A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS.
Brandon Mark, Sen-Lin Lai, Aref Arzan Zarin, Laurina Manning, Heather Q Pollington, Ashok Litwin-Kumar, Albert Cardona, James W Truman, Chris Q Doe
Jun 11, 2021
The mechanisms specifying neuronal diversity are well characterized, yet it remains unclear how or if these mechanisms regulate neural circuit assembly. To address this, we mapped the developmental origin of 160 interneurons...
Utility of 5-ALA for resection of CNS tumours other than high-grade gliomas
Georgios Solomou, Aref-Ali Gharooni, Waqqas Patel, Conor S Gillespie, Melissa Gough, Ashwin Venkatesh, Michael TC Poon, Victoria Wykes, Stephen John Price, Michael D Jenkinson, Colin Watts, Puneet Plaha
Jul 27, 2022
INTRODUCTION: 5-aminolevulinic acid (5-ALA) is a proagent developed for fluorescent-guided surgery for high-grade glioma patients associated with a significant increase in resection conferring survival. 5-ALA was shown to...
Location, number and factors associated with cerebral microbleeds in an Italian-British cohort of CADASIL patients.
Serena Nannucci, Valentina Rinnoci, Giovanni Pracucci, Andrew D MacKinnon, Francesca Pescini, Poneh Adib-Samii, Silvia Bianchi, Maria Teresa Dotti, Antonio Federico, Domenico Inzitari, Hugh S Markus, Leonardo Pantoni
Apr 12, 2018
BACKGROUND AND PURPOSE: The frequency, clinical correlates, and risk factors of cerebral microbleeds (CMB) in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) are still poorly...
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.
Daniel E Martin-Herranz, Erfan Aref-Eshghi, Marc Jan Bonder, Thomas M Stubbs, Sanaa Choufani, Rosanna Weksberg, Oliver Stegle, Bekim Sadikovic, Wolf Reik, Janet M Thornton
Aug 13, 2020
BACKGROUND: Epigenetic clocks are mathematical models that predict the biological age of an individual using DNA methylation data and have emerged in the last few years as the most accurate biomarkers of the aging process....
aging Biological age DNA Methylation Developmental disorder Epigenetic clock epigenetics H3K36 methylation Methylation entropy NSD1 Sotos syndrome Adult aging Biological Clocks CpG Islands DNA Methylation Entropy Epigenesis Genetic Genetic Testing Genome Human Histone-Lysine N-Methyltransferase Histones Humans Infant Lysine Models Genetic Sotos Syndrome
Common NOTCH3 Variants and Cerebral Small-Vessel Disease.
Even-Skipped(+) Interneurons Are Core Components of a Sensorimotor Circuit that Maintains Left-Right Symmetric Muscle Contraction Amplitude.
The Relative Merits of Posterior Surgical Treatments for Multi-Level Degenerative Cervical Myelopathy Remain Uncertain
Xiaoyu Yang, Aref-Ali Gharooni, Rana S. Dhillon, Edward Goacher, Edward W. Dyson, Oliver Mowforth, Alexandru Budu, Guy Wynne-Jones, Jibin Francis, Rikin Trivedi, Marcel Ivanov, Sashin Ahuja, Kia Rezajooi, Andreas K. Demetriades, David Choi, Antony H. Bateman, Nasir Quraishi, Vishal Kumar, Manjul Tripathi, Sandeep Mohindra, Erlick A. Pereira, Giles Critchley, Michael G. Fehlings, Peter J. A. Hutchinson, Benjamin M. Davies, Mark R. N. Kotter
Aug 26, 2021
Objectives: To assess the reporting of study design and characteristics in multi-level degenerative cervical myelopathy (DCM) treated by posterior surgical approaches, and perform a comparison of clinical and radiographic...
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