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Lysosome positioning and mTOR activity in Lowe syndrome.
Lowe syndrome is a rare, developmental disorder caused by mutations in the phosphatase, OCRL. A study in this issue of EMBO Reports shows that OCRL is required for microtubule nucleation and that mutations in this protein lead...
Heteroclinic travelling waves for the lattice sine-Gordon equation with linear pair interaction
The existence of travelling heteroclinic waves for the sine-Gordon lattice is proved for a linear interaction of neighbouring atoms. The asymptotic states are chosen such that the action functional is finite. The proof relies on...
Sine-Gordon on a wormhole
In an attempt to understand the soliton resolution conjecture, we consider
the Sine-Gordon equation on a spherically symmetric wormhole spacetime. We show
that within each topological sector (indexed by a positive integer degree...
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.
Maria Giovanna De Leo, Leopoldo Staiano, Mariella Vicinanza, Alessandro Luciani, Annamaria Carissimo, Margherita Mutarelli, Antonella Di Campli, Elena Polishchuk, Giuseppe Di Tullio, Valentina Morra, Elena Levtchenko, Francesca Oltrabella, Tobias Starborg, Michele Santoro, Diego di Bernardo, Olivier Devuyst, Martin Lowe, Diego L Medina, Andrea Ballabio, Maria Antonietta De Matteis
Sep 03, 2019
Phosphoinositides (PtdIns) control fundamental cell processes, and inherited defects of PtdIns kinases or phosphatases cause severe human diseases, including Lowe syndrome due to mutations in OCRL, which encodes a PtdIns(4,5)P2...
Sine-Gordon on a wormhole
Abstract: In an attempt to understand the soliton resolution conjecture, we consider the sine-Gordon equation on a spherically symmetric wormhole spacetime. We show that within each topological sector (indexed by a positive...
Sine-Gordon on a wormhole
Abstract: In an attempt to understand the soliton resolution conjecture, we consider the sine-Gordon equation on a spherically symmetric wormhole spacetime. We show that within each topological sector (indexed by a positive...
Travelling wave solutions for the discrete sine-Gordon equation with nonlinear pair interaction
The focus of study is the nonlinear discrete sine-Gordon equation, where the nonlinearity refers to a nonlinear interaction of neighbouring atoms. The existence of travelling heteroclinic, homoclinic and periodic waves is shown....
The Merry Wives of Windsor
Daniel Gordon
Jan 01, 0001
The Merry Wives of Windsor A story of LUST, GREED, and DIRTY LAUNDRYBy William Shakespeare, adapted by Daniel Gordon.
Shakespeare's The Merry Wives of Windsor uses more prose than any of his other plays, for indeed, these...
William Shakespeare Shakespeare Carolina Acting Dramatic Literature, Criticism and Theory Literature in English, British Isles Performance Studies
Published by: Winthrop University
Heteroclinic travelling waves for the lattice sine-Gordon equation with linear pair interaction
The existence of travelling heteroclinic waves for the sine-Gordon lattice is proved for a linear interaction of neighbouring atoms. The asymptotic states are chosen such that the action functional is finite. The proof relies on...
Log‐Sobolev Inequality for the Continuum Sine‐Gordon Model
We derive a multiscale generalisation of the Bakry‐Émery criterion for a measure to satisfy a log‐Sobolev inequality. Our criterion relies on the control of an associated PDE well‐known in renormalisation theory: the Polchinski...
Travelling wave solutions for the discrete sine-Gordon equation with nonlinear pair interaction
The focus of study is the nonlinear discrete sine-Gordon equation, where the nonlinearity refers to a nonlinear interaction of neighbouring atoms. The existence of travelling heteroclinic, homoclinic and periodic waves is shown....
First do no harm
Timo Kivimaki
Dec 01, 2015
A recent revelation by President and Nobel Peace Prize laureate Martti Ahtisaari suggests that the large scale destruction of Syria could perhaps have been avoided by diplomacy. However, the negotiated solution was not accepted...
First do no harm
Timo Kivimaki
Dec 01, 2015
A recent revelation by President and Nobel Peace Prize laureate Martti Ahtisaari suggests that the large scale destruction of Syria could perhaps have been avoided by diplomacy. However, the negotiated solution was not accepted...
What Do Academic Library Deans Do?
Mark Y. Herring
Jan 01, 0001
A recent discussion apropos of nothing set me to a thought-experiment: what is it deans of library services (or, as it often the case when I'm introduced, deans of library sciences) do? If one were to write up a short list of...
Published by: Winthrop University
Tarsila do Amaral
Sofia Gotti
Feb 18, 2020
Tarsila do Amaral: Inventing Modern Art in Brazil sets out to confront "the issues of race, class, and gender in Brazil . . . as well as larger matters of nationalism and internationalism, primitivism and colonial history and...
Nuclear and Plasma Membrane Properties of Macrophage Heterokaryons and Hybrids
Siamon Gordon
Jan 01, 0001
Mouse peritoneal macrophages, which do not synthesize DNA in vitro, were fused with a strain of mouse melanoma cells which proliferates rapidly in vitro. The plasma membrane of the macrophage has specific receptors which enable...
Published by: Rockefeller University
Considering planned change anew
Large Group Interventions, methods for involving “the whole system” in a change process, are important contemporary planned organizational change approaches. They are well known to practitioners but unfamiliar to many...
Central Missouri State Professor to Chair Modern Languages Department
Winthrop University
Jan 01, 0001
On Aug. 1, Kenneth Gordon will replace Sarah Stallings as chair of the Department of Modern Languages. Gordon, a professor at Central Missouri State University, will teach in the Netherlands in May.
Published by: Winthrop University
Considering planned change anew
Large Group Interventions, methods for involving “the whole system” in a change process, are important contemporary planned organizational change approaches. They are well known to practitioners but unfamiliar to many...
Why do People Blame Others?
According to Amanda Watson when the situation is "someone else's fault", then there's little reason to do anything further about it, let alone seek to understand the role that one's own behaviour, feelings or assumptions might...
Published by: Department of History, University of Karachi
Chicago Symphony Orchestra Percussionist Holds Concert April 6
Winthrop University
Jan 01, 0001
The Winthrop Percussion and Marimba Ensembles will play a concert with percussionist Gordon Peters on April 6. Peters has performed with the Chicago Symphony Orchestra for 42 years.
Published by: Winthrop University
The Law of Double Consonants in Inuktitut
In this article we examine a number of properties having to do with Schneider's Law in Inuktitut, also referred to as the Law of Double Consonants. This phonological rule simplifies a consonant cluster from two to one when there...
Published by: Atlantic Provinces Linguistic Association
The Law of Double Consonants in Inuktitut
In this article we examine a number of properties having to do with Schneider's Law in Inuktitut, also referred to as the Law of Double Consonants. This phonological rule simplifies a consonant cluster from two to one when there...
Published by: Atlantic Provinces Linguistic Association
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