Distal lung epithelial progenitor cell function declines with age.
Julie K Watson,
Philip Sanders,
Rebecca Dunmore,
Guglielmo Rosignoli,
Yvon Julé,
Emma L Rawlins,
Tomas Mustelin,
Richard May,
Deborah Clarke,
Donna K Finch
Jul 07, 2020
Tissue stem cell exhaustion is a key hallmark of aging, and in this study, we characterised its manifestation in the distal lung. We compared the lungs of 3- and 22-month old mice. We examined the gross morphological changes in...